Spontaneous development of autoimmune arthritis due to genetic anomaly of T cell signal transduction: Part 1

Seminars in Immunology

Volumn 18, Issue 4, 2006, Pages 199-206

  Sakaguchi, Shimon ^a,b   Sakaguchi, Noriko ^a,b   Yoshitomi, Hiroyuki ^a,b   Hata, Hiroshi ^a,b   Takahashi, Takeshi ^a,b   Nomura, Takashi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Animal model; Autoimmune arthritis; Regulatory T cell; Rheumatoid arthritis; T cell selection; ZAP 70

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; PROTEIN KINASE ZAP 70;

ARTHRITIS; AUTOIMMUNE ARTHRITIS; AUTOIMMUNE DISEASE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL MATURATION; CELL SELECTION; DISEASE MODEL; ENVIRONMENTAL FACTOR; EXPERIMENTAL MOUSE; GENE MUTATION; GENETIC DISORDER; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HOMOZYGOTE; HUMAN; IMMUNOPATHOLOGY; IMMUNOREGULATION; INNATE IMMUNITY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MICROORGANISM; NONHUMAN; PATHOGENESIS; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS;

ANIMALS; ARTHRITIS, RHEUMATOID; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 33745156509     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2006.03.007     Document Type: Review

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