메뉴 건너뛰기




Volumn 211, Issue , 2006, Pages 104-118

The rationale for the IL-2-independent generation of the self-renewing central memory CD8+ T cells

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR;

EID: 33745112262     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2006.00390.x     Document Type: Review
Times cited : (25)

References (55)
  • 1
    • 0035854521 scopus 로고    scopus 로고
    • Arrested differentiation, the self-renewing memory lymphocyte, and vaccination
    • Fearon DT Manders P Wagner SD. Arrested differentiation, the self-renewing memory lymphocyte, and vaccination. Science 2001 293: 248 250.
    • (2001) Science , vol.293 , pp. 248-250
    • Fearon, D.T.1    Manders, P.2    Wagner, S.D.3
  • 2
    • 21644453108 scopus 로고    scopus 로고
    • Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination
    • Wherry EJ Blattman JN Ahmed R. Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. J Virol 2005 79: 8960 8968.
    • (2005) J Virol , vol.79 , pp. 8960-8968
    • Wherry, E.J.1    Blattman, J.N.2    Ahmed, R.3
  • 3
    • 85047692244 scopus 로고    scopus 로고
    • Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
    • Sevilla N McGavern DB Teng C Kunz S Oldstone MB. Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion. J Clin Invest 2004 113: 737 745.
    • (2004) J Clin Invest , vol.113 , pp. 737-745
    • Sevilla, N.1    McGavern, D.B.2    Teng, C.3    Kunz, S.4    Oldstone, M.B.5
  • 4
    • 0037442113 scopus 로고    scopus 로고
    • Memory inflation: Continuous accumulation of antiviral CD8+ T cells over time
    • Karrer U, et al. Memory inflation: continuous accumulation of antiviral CD8+ T cells over time. J Immunol 2003 170: 2022 2029.
    • (2003) J Immunol , vol.170 , pp. 2022-2029
    • Karrer, U.1
  • 5
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F Lenig D Forster R Lipp M Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999 401: 708 712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 6
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt RL Khoruts A Merica R Zell T Jenkins MK. Visualizing the generation of memory CD4 T cells in the whole body. Nature 2001 410: 101 105.
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 7
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust D Vezys V Marzo AL Lefrancois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001 291: 2413 2417.
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 9
    • 0036839358 scopus 로고    scopus 로고
    • Lymphotoxin-alpha-deficient mice make delayed, but effective, T and B cell responses to influenza
    • Lund FE, et al. Lymphotoxin-alpha-deficient mice make delayed, but effective, T and B cell responses to influenza. J Immunol 2002 169: 5236 5243.
    • (2002) J Immunol , vol.169 , pp. 5236-5243
    • Lund, F.E.1
  • 10
    • 4644330206 scopus 로고    scopus 로고
    • Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity
    • Moyron-Quiroz JE, et al. Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat Med 2004 10: 927 934.
    • (2004) Nat Med , vol.10 , pp. 927-934
    • Moyron-Quiroz, J.E.1
  • 11
    • 0034613152 scopus 로고    scopus 로고
    • Dynamics of T lymphocyte responses: Intermediates, effectors, and memory cells
    • Lanzavecchia A Sallusto F. Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 2000 290: 92 97.
    • (2000) Science , vol.290 , pp. 92-97
    • Lanzavecchia, A.1    Sallusto, F.2
  • 12
    • 20244375369 scopus 로고    scopus 로고
    • Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes
    • Manjunath N, et al. Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. J Clin Invest 2001 108: 871 878.
    • (2001) J Clin Invest , vol.108 , pp. 871-878
    • Manjunath, N.1
  • 13
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8 T cell subsets
    • Wherry EJ, et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol 2003 4: 225 234.
    • (2003) Nat Immunol , vol.4 , pp. 225-234
    • Wherry, E.J.1
  • 14
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM Tan JT Wherry EJ Konieczny BT Surh CD Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 2003 4: 1191 1198.
    • (2003) Nat Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 15
    • 8644219870 scopus 로고    scopus 로고
    • Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice
    • Pellegrini M Bouillet P Robati M Belz GT Davey GM Strasser A. Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice. J Exp Med 2004 200: 1189 1195.
    • (2004) J Exp Med , vol.200 , pp. 1189-1195
    • Pellegrini, M.1    Bouillet, P.2    Robati, M.3    Belz, G.T.4    Davey, G.M.5    Strasser, A.6
  • 17
    • 5344280456 scopus 로고    scopus 로고
    • MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation
    • Fujita N, et al. MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell 2004 119: 75 86.
    • (2004) Cell , vol.119 , pp. 75-86
    • Fujita, N.1
  • 18
    • 2442700374 scopus 로고    scopus 로고
    • Cutting edge: Effector memory CD8+ T cells play a prominent role in recall responses to secondary viral infection in the lung
    • Roberts AD Woodland DL. Cutting edge: effector memory CD8+ T cells play a prominent role in recall responses to secondary viral infection in the lung. J Immunol 2004 172: 6533 6537.
    • (2004) J Immunol , vol.172 , pp. 6533-6537
    • Roberts, A.D.1    Woodland, D.L.2
  • 19
    • 22344434167 scopus 로고    scopus 로고
    • Differential contributions of central and effector memory T cells to recall responses
    • Roberts AD Ely KH Woodland DL. Differential contributions of central and effector memory T cells to recall responses. J Exp Med 2005 202: 123 133.
    • (2005) J Exp Med , vol.202 , pp. 123-133
    • Roberts, A.D.1    Ely, K.H.2    Woodland, D.L.3
  • 20
    • 25444461647 scopus 로고    scopus 로고
    • Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L
    • Bachmann MF Wolint P Schwarz K Jager P Oxenius A. Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L. J Immunol 2005 175: 4686 4696.
    • (2005) J Immunol , vol.175 , pp. 4686-4696
    • Bachmann, M.F.1    Wolint, P.2    Schwarz, K.3    Jager, P.4    Oxenius, A.5
  • 21
    • 14244259568 scopus 로고    scopus 로고
    • Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo
    • Bouneaud C Garcia Z Kourilsky P Pannetier C. Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo. J Exp Med 2005 201: 579 590.
    • (2005) J Exp Med , vol.201 , pp. 579-590
    • Bouneaud, C.1    Garcia, Z.2    Kourilsky, P.3    Pannetier, C.4
  • 22
    • 0037017383 scopus 로고    scopus 로고
    • Differential T cell function and fate in lymph node and nonlymphoid tissues
    • Harris NL Watt V Ronchese F Le Gros G. Differential T cell function and fate in lymph node and nonlymphoid tissues. J Exp Med 2002 195: 317 326.
    • (2002) J Exp Med , vol.195 , pp. 317-326
    • Harris, N.L.1    Watt, V.2    Ronchese, F.3    Le Gros, G.4
  • 24
    • 15244348992 scopus 로고    scopus 로고
    • Complex memory T-cell phenotypes revealed by coexpression of CD62L and CCR7
    • Unsoeld H Pircher H. Complex memory T-cell phenotypes revealed by coexpression of CD62L and CCR7. J Virol 2005 79: 4510 4513.
    • (2005) J Virol , vol.79 , pp. 4510-4513
    • Unsoeld, H.1    Pircher, H.2
  • 25
    • 2142815852 scopus 로고    scopus 로고
    • Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: Correlation of cytokine profile and TCR avidity
    • La Gruta NL Turner SJ Doherty PC. Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity. J Immunol 2004 172: 5553 5560.
    • (2004) J Immunol , vol.172 , pp. 5553-5560
    • La Gruta, N.L.1    Turner, S.J.2    Doherty, P.C.3
  • 26
    • 1842681952 scopus 로고    scopus 로고
    • Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets
    • Huster KM, et al. Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. Proc Natl Acad Sci USA 2004 101: 5610 5615.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 5610-5615
    • Huster, K.M.1
  • 27
    • 0034684672 scopus 로고    scopus 로고
    • Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6
    • Reljic R Wagner SD Peakman LJ Fearon DT. Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6. J Exp Med 2000 192: 1841 1848.
    • (2000) J Exp Med , vol.192 , pp. 1841-1848
    • Reljic, R.1    Wagner, S.D.2    Peakman, L.J.3    Fearon, D.T.4
  • 28
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • Shaffer AL Yu X He Y Boldrick J Chan EP Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 2000 13: 199 212.
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1    Yu, X.2    He, Y.3    Boldrick, J.4    Chan, E.P.5    Staudt, L.M.6
  • 29
    • 0036078187 scopus 로고    scopus 로고
    • Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells
    • Ichii H, et al. Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells. Nat Immunol 2002 3: 558 563.
    • (2002) Nat Immunol , vol.3 , pp. 558-563
    • Ichii, H.1
  • 30
    • 3142779955 scopus 로고    scopus 로고
    • Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells
    • Ichii H Sakamoto A Kuroda Y Tokuhisa T. Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells. J Immunol 2004 173: 883 891.
    • (2004) J Immunol , vol.173 , pp. 883-891
    • Ichii, H.1    Sakamoto, A.2    Kuroda, Y.3    Tokuhisa, T.4
  • 31
    • 21144449046 scopus 로고    scopus 로고
    • BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes
    • Manders PM, et al. BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proc Natl Acad Sci USA 2005 102: 7418 7425.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7418-7425
    • Manders, P.M.1
  • 32
    • 0035169598 scopus 로고    scopus 로고
    • BCL-6 protein is expressed in precursor T-cell lymphoblastic lymphoma and in prenatal and postnatal thymus
    • Hyjek E Chadburn A Liu YF Cesarman E Knowles DM. BCL-6 protein is expressed in precursor T-cell lymphoblastic lymphoma and in prenatal and postnatal thymus. Blood 2001 97: 270 276.
    • (2001) Blood , vol.97 , pp. 270-276
    • Hyjek, E.1    Chadburn, A.2    Liu, Y.F.3    Cesarman, E.4    Knowles, D.M.5
  • 33
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Dent AL Shaffer AL Yu X Allman D Staudt LM. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 1997 276: 589 592.
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 34
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
    • Ye BH, et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet 1997 16: 161 170.
    • (1997) Nat Genet , vol.16 , pp. 161-170
    • Ye, B.H.1
  • 35
    • 0030763072 scopus 로고    scopus 로고
    • Disruption of the Bcl6 gene results in an impaired germinal center formation
    • Fukuda T, et al. Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med 1997 186: 439 448.
    • (1997) J Exp Med , vol.186 , pp. 439-448
    • Fukuda, T.1
  • 36
    • 0034278508 scopus 로고    scopus 로고
    • BCL-6 regulates chemokine gene transcription in macrophages
    • Toney LM, et al. BCL-6 regulates chemokine gene transcription in macrophages. Nat Immunol 2000 1: 214 220.
    • (2000) Nat Immunol , vol.1 , pp. 214-220
    • Toney, L.M.1
  • 37
    • 0031595261 scopus 로고    scopus 로고
    • BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor
    • Okabe S, et al. BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor. Mol Cell Biol 1998 18: 4235 4244.
    • (1998) Mol Cell Biol , vol.18 , pp. 4235-4244
    • Okabe, S.1
  • 38
    • 13544262333 scopus 로고    scopus 로고
    • BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production
    • Yu RY, et al. BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production. Blood 2005 105: 1777 1784.
    • (2005) Blood , vol.105 , pp. 1777-1784
    • Yu, R.Y.1
  • 39
    • 0032827421 scopus 로고    scopus 로고
    • Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: Specific regulation of iepsilon transcription and immunoglobulin e switching
    • Harris MB, et al. Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching. Mol Cell Biol 1999 19: 7264 7275.
    • (1999) Mol Cell Biol , vol.19 , pp. 7264-7275
    • Harris, M.B.1
  • 41
    • 0029025841 scopus 로고
    • Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4
    • Bachmann MF, et al. Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4. J Virol 1995 69: 4842 4846.
    • (1995) J Virol , vol.69 , pp. 4842-4846
    • Bachmann, M.F.1
  • 42
    • 0028843720 scopus 로고
    • Endogenous IL-2 contributes to T cell expansion and IFN-gamma production during lymphocytic choriomeningitis virus infection
    • Cousens LP Orange JS Biron CA. Endogenous IL-2 contributes to T cell expansion and IFN-gamma production during lymphocytic choriomeningitis virus infection. J Immunol 1995 155: 5690 5699.
    • (1995) J Immunol , vol.155 , pp. 5690-5699
    • Cousens, L.P.1    Orange, J.S.2    Biron, C.A.3
  • 43
    • 0028142358 scopus 로고
    • Thymic selection and peptide-induced activation of T cell receptor-transgenic CD8 T cells in interleukin-2-deficient mice
    • Kramer S Mamalaki C Horak I Schimpl A Kioussis D Hung T. Thymic selection and peptide-induced activation of T cell receptor-transgenic CD8 T cells in interleukin-2-deficient mice. Eur J Immunol 1994 24: 2317 2322.
    • (1994) Eur J Immunol , vol.24 , pp. 2317-2322
    • Kramer, S.1    Mamalaki, C.2    Horak, I.3    Schimpl, A.4    Kioussis, D.5    Hung, T.6
  • 44
    • 0036604208 scopus 로고    scopus 로고
    • Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses
    • D'Souza WN Schluns KS Masopust D Lefrancois L. Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses. J Immunol 2002 168: 5566 5572.
    • (2002) J Immunol , vol.168 , pp. 5566-5572
    • D'Souza, W.N.1    Schluns, K.S.2    Masopust, D.3    Lefrancois, L.4
  • 45
    • 0345447666 scopus 로고    scopus 로고
    • IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion
    • D'Souza WN Lefrancois L. IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion. J Immunol 2003 171: 5727 5735.
    • (2003) J Immunol , vol.171 , pp. 5727-5735
    • D'Souza, W.N.1    Lefrancois, L.2
  • 46
    • 0037093844 scopus 로고    scopus 로고
    • Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
    • Schluns KS Williams K Ma A Zheng XX Lefrancois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 2002 168: 4827 4831.
    • (2002) J Immunol , vol.168 , pp. 4827-4831
    • Schluns, K.S.1    Williams, K.2    Ma, A.3    Zheng, X.X.4    Lefrancois, L.5
  • 47
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
    • Becker TC, et al. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002 195: 1541 1548.
    • (2002) J Exp Med , vol.195 , pp. 1541-1548
    • Becker, T.C.1
  • 48
    • 0037222183 scopus 로고    scopus 로고
    • Efficient induction of primary and secondary T cell-dependent immune responses in vivo in the absence of functional IL-2 and IL-15 receptors
    • Yu A, et al. Efficient induction of primary and secondary T cell-dependent immune responses in vivo in the absence of functional IL-2 and IL-15 receptors. J Immunol 2003 170: 236 242.
    • (2003) J Immunol , vol.170 , pp. 236-242
    • Yu, A.1
  • 49
    • 0019507147 scopus 로고
    • Monoclonal antibody directed against interleukin 2. I. Inhibition of T lymphocyte mitogenesis and the in vitro differentiation of alloreactive cytolytic T cells
    • Gillis S Gillis AE Henney CS. Monoclonal antibody directed against interleukin 2. I. Inhibition of T lymphocyte mitogenesis and the in vitro differentiation of alloreactive cytolytic T cells. J Exp Med 1981 154: 983 988.
    • (1981) J Exp Med , vol.154 , pp. 983-988
    • Gillis, S.1    Gillis, A.E.2    Henney, C.S.3
  • 50
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS Kieper WC Jameson SC Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000 1: 426 432.
    • (2000) Nat Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 51
    • 8544234990 scopus 로고    scopus 로고
    • Recent developments in the transcriptional regulation of cytolytic effector cells
    • Glimcher LH Townsend MJ Sullivan BM Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol 2004 4: 900 911.
    • (2004) Nat Rev Immunol , vol.4 , pp. 900-911
    • Glimcher, L.H.1    Townsend, M.J.2    Sullivan, B.M.3    Lord, G.M.4
  • 52
    • 0242410712 scopus 로고    scopus 로고
    • Control of effector CD8+ T cell function by the transcription factor Eomesodermin
    • Pearce EL, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science 2003 302: 1041 1043.
    • (2003) Science , vol.302 , pp. 1041-1043
    • Pearce, E.L.1
  • 53
    • 30044440799 scopus 로고    scopus 로고
    • Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
    • Intlekofer AM, et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol 2005 6: 1236 1244.
    • (2005) Nat Immunol , vol.6 , pp. 1236-1244
    • Intlekofer, A.M.1
  • 54
    • 0037037568 scopus 로고    scopus 로고
    • Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8+ T cells
    • Judge AD Zhang X Fujii H Surh CD Sprent J. Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8+ T cells. J Exp Med 2002 196: 935 946.
    • (2002) J Exp Med , vol.196 , pp. 935-946
    • Judge, A.D.1    Zhang, X.2    Fujii, H.3    Surh, C.D.4    Sprent, J.5
  • 55
    • 0037124362 scopus 로고    scopus 로고
    • Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells
    • Goldrath AW, et al. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J Exp Med 2002 195: 1515 1522.
    • (2002) J Exp Med , vol.195 , pp. 1515-1522
    • Goldrath, A.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.