Migratory properties of naive, effector, and memory CD8+ T cells

Journal of Experimental Medicine

Volumn 194, Issue 7, 2001, Pages 953-966

  Weninger, W ^a   Crowley, M A ^a   Manjunath, N ^a   Von Andrian, U H ^a  

^a CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

Adhesion molecules; Chemokines; Inflammation; Lymph node; Lymphocyte homing

Indexed keywords

CD8 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE; CHEMOKINE RECEPTOR; INTERLEUKIN 15; INTERLEUKIN 2; L SELECTIN;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXIC LYMPHOCYTE; EFFECTOR CELL; FEMALE; INFLAMMATION; LYMPHOCYTE CULTURE; LYMPHOCYTE HOMING; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MALE; MEMORY CELL; MICROSCOPY; MOUSE; NONHUMAN; PERITONITIS; PEYER PATCH; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR BINDING; SPLEEN; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; BLOOD CIRCULATION; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CHEMOTAXIS, LEUKOCYTE; FEMALE; IMMUNOLOGIC MEMORY; INFLAMMATION; INTERLEUKIN-15; INTERLEUKIN-2; LYMPH NODES; LYMPHATIC SYSTEM; MALE; MICE; PEYER'S PATCHES; SPLEEN; T-LYMPHOCYTE SUBSETS;

EID: 0035477154     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.7.953     Document Type: Article

References (63)

1. Lymphocyte homing and homeostasis
2. T-cell function and migration. Two sides of the same coin
3. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
4. Molecular pathways of CTL-mediated cytotoxicity
5. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multi-step paradigm
6. A cell-surface molecule involved in organ-specific homing of lymphocytes
7. Lymphocyte homing and leukocyte rolling and migration are impaired ill L-selectin-deficient mice
8. Molecular mechanisms of lymphocyte homing to peripheral lymph nodes
9. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
10. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization
11. Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice
12. Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice
13. The role of chemokines in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venules
14. The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules
15. A transgenic mouse model to analyze CD8+ effector T cell differentiation in vivo
16. Differentiating between memory and effector CD8 T cells by altered expression of cell surface O-glycans
17. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
18. Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes
19. T and B memory cells
20. Immunological memory and protective immunity: Understanding their relation
21. T cell memory
22. Visualizing the generation of memory CD4 T cells in the whole body
23. Preferential localization of effector memory cells in nonlymphoid tissue
24. Naive and memory T cells show distinct pathways of lymphocyte recirculation
25. T-cell memory: The connection between function, phenotype and migration pathways
26. How organ-specific is the migration of 'naive' and 'memory' T cells?
27. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
28. + memory T cells by opposing cytokines
29. The route of antigen entry determines the requirement for L-selectin during immune responses
30. Intravital microscopy of the peripheral lymph node microcirculation in mice
31. In situ analysis of lymphocyte migration to lymph nodes
32. Following cellular traffic: Methods of labelling lymphocytes and other cells to trace their migration in vivo
33. Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords
34. The role of CCR7 in TH1 and TH2 cell localization and delivery of B cell help in vivo
35. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
36. Chemokines: A new classification system and their role in immunity
37. A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4
38. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes
39. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse
40. Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes
41. The role of chemokine receptors in primary, effector, and memory immune responses
42. Acquisition of selectin binding and peripheral homing properties by CD4+ and CD8+ T cells
43. Migration and function of antigen-primed nonpolarized T lymphocytes in vivo
44. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflammed tissues
45. P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin
46. The migratory behavior of murine CD4 cells of memory phenowpe
47. Th1/Th2 subsets: Distinct differences in homing and chemokine receptor expression?
48. Activation induces rapid and profound alterations in the trafficking of T cells
49. Migration kinetics and final destination of Type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection
50. Differentiation of naive CTL to effector and memory CTL: Correlation of effector function with phenotype and cell division
51. + memory T cell subsets in persistent EBV infection are differentiated by migratory receptor expression
52. Homing of naive and memory T lymphocyte subsets to Peyer's patches, lymphnodes, and spleen
53. Distinct migration patterns of naive and effector CD8 T cells in the spleen: Correlation with CCR7 receptor expression and chemokine reactivity
54. Dendritic cells in the T-cell areas of lymphoid organs
55. Dendritic cells and the control of immunity
56. - dendritic cells cross-prime cytotoxic T cells in vivo
57. Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice
58. Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing
59. + T cells increase during viral infection and migrate to sites of infection
60. Requirement for CD44 in activated T cell extravasation into an inflammatory site
61. The α(1,3) fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis
62. Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation
63. Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels