Tau Paired Helical Filaments from Alzheimer's Disease Brain and Assembled in Vitro Are Based on β-Structure in the Core Domain

Biochemistry

Volumn 43, Issue 6, 2004, Pages 1694-1703

  Barghorn, Stefan ^a   Davies, Peter ^b   Mandelkow, Eckhard ^a  

^a M Planck U Struct Molec Biol   (Germany)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BRAIN; DISEASES; ELECTRON MICROSCOPY; IMMUNOLOGY; PURIFICATION; SOLUBILITY; SPECTROSCOPIC ANALYSIS;

HELICAL STRUCTURES; REASSEMBLED FIBERS;

BIOCHEMISTRY;

TAU PROTEIN;

ALPHA HELIX; ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN TISSUE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SPECTROSCOPY; TAUOPATHY;

ALZHEIMER DISEASE; AMYLOID; BLOTTING, WESTERN; BRAIN CHEMISTRY; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; NEUROFIBRILLARY TANGLES; NEUROFILAMENT PROTEINS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TAU PROTEINS;

EID: 1042288284     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0357006     Document Type: Article

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