Latent pathway activation and increased pathway capacity enable Escherichia coli adaptation to loss of key metabolic enzymes

Journal of Biological Chemistry

Volumn 281, Issue 12, 2006, Pages 8024-8033

  Fong, Stephen S ^c   Nanchen, Annik ^a   Palsson, Bernhard O ^b   Sauer, Uwe ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Virginia Commonwealth University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIODIVERSITY; ENZYMES; METABOLISM; RNA;

BIOLOGICAL SYSTEMS; METABOLIC FLUXES; TRICARBOXYLIC ACID;

ESCHERICHIA COLI;

BACTERIAL ENZYME; MESSENGER RNA; BACTERIAL PROTEIN; CARBON; ESCHERICHIA COLI PROTEIN; GLYCEROL; LEUO PROTEIN, E COLI; METHIONINE REPRESSOR PROTEIN, BACTERIA; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ADAPTATION; ARTICLE; BACTERIAL METABOLISM; BACTERIUM MUTANT; CITRIC ACID CYCLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DYNAMICS; ENZYME ACTIVATION; ESCHERICHIA COLI; EVOLUTION; GENE DELETION; INTRACELLULAR SPACE; LATENT PERIOD; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA TRANSCRIPTION; ANIMAL; BACTERIAL PHENOMENA AND FUNCTIONS; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMISTRY; DNA MICROARRAY; GENETIC TRANSCRIPTION; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; METABOLISM; MOLECULAR EVOLUTION; MOUSE; MOUSE MUTANT; MUTATION; PHYSIOLOGY; PROTEIN SYNTHESIS;

ESCHERICHIA COLI;

ANIMALS; BACTERIAL PHYSIOLOGY; BACTERIAL PROTEINS; CARBON; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EVOLUTION; EVOLUTION, MOLECULAR; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE DELETION; GLYCEROL; MASS SPECTROMETRY; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, GENETIC; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PROTEIN BIOSYNTHESIS; REPRESSOR PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 33646362289     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510016200     Document Type: Article

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