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Volumn 55, Issue 5, 2005, Pages 245-254

Cardiac developmental biology: From flies to humans

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CSX; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN;

EID: 33646249816     PISSN: 0021521X     EISSN: 0021521X     Source Type: Journal    
DOI: 10.2170/jjphysiol.M94     Document Type: Review
Times cited : (6)

References (94)
  • 1
    • 0027738464 scopus 로고
    • The MyoD family and myogenesis: Redundancy, networks, and thresholds
    • Weintraub H: The MyoD family and myogenesis: redundancy, networks, and thresholds. Cell 75: 1241-1244, 1993
    • (1993) Cell , vol.75 , pp. 1241-1244
    • Weintraub, H.1
  • 2
    • 0025201511 scopus 로고
    • A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila
    • Bodmer R, Jan LY, and Jan YN: A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila. Development 110: 661-669, 1990
    • (1990) Development , vol.110 , pp. 661-669
    • Bodmer, R.1    Jan, L.Y.2    Jan, Y.N.3
  • 3
    • 0027237596 scopus 로고
    • Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
    • Azpiazu N and Frasch M: tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev 7: 1325-1340, 1993
    • (1993) Genes Dev , vol.7 , pp. 1325-1340
    • Azpiazu, N.1    Frasch, M.2
  • 4
    • 0027282774 scopus 로고
    • The gene tinman is required for specification of the heart and visceral muscles in Drosophila
    • Bodmer R: The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118: 719-729, 1993
    • (1993) Development , vol.118 , pp. 719-729
    • Bodmer, R.1
  • 5
    • 0027184211 scopus 로고
    • Csx: A murine homeobox-containing gene specifically expressed in the developing heart
    • USA
    • Komuro I and Izumo S: Csx: a murine homeobox-containing gene specifically expressed in the developing heart. Proc Natl Acad Sci USA 90: 8145-8149, 1993
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 8145-8149
    • Komuro, I.1    Izumo, S.2
  • 6
    • 0027383023 scopus 로고
    • Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
    • Lints TJ, Parsons LM, Hartley L, Lyons I, and Harvey RP: Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119: 419-431, 1993
    • (1993) Development , vol.119 , pp. 419-431
    • Lints, T.J.1    Parsons, L.M.2    Hartley, L.3    Lyons, I.4    Harvey, R.P.5
  • 7
    • 0028294694 scopus 로고
    • XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development
    • Tonissen KF, Drysdale TA, Lints TJ, Harvey RP, and Krieg PA: XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development. Dev Biol 162: 325-328, 1994
    • (1994) Dev Biol , vol.162 , pp. 325-328
    • Tonissen, K.F.1    Drysdale, T.A.2    Lints, T.J.3    Harvey, R.P.4    Krieg, P.A.5
  • 8
    • 0030465318 scopus 로고    scopus 로고
    • Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation
    • Chen JN and Fishman MC: Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122: 3809-3816, 1996
    • (1996) Development , vol.122 , pp. 3809-3816
    • Chen, J.N.1    Fishman, M.C.2
  • 9
    • 0029583152 scopus 로고
    • Induction of avian cardiac myogenesis by anterior endoderm
    • Schultheiss TM, Xydas S, and Lassar AB: Induction of avian cardiac myogenesis by anterior endoderm. Development 121: 4203-4214, 1995
    • (1995) Development , vol.121 , pp. 4203-4214
    • Schultheiss, T.M.1    Xydas, S.2    Lassar, A.B.3
  • 11
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
    • Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, Robb L, and Harvey RP: Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev 9: 1654-1666, 1995
    • (1995) Genes Dev , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5    Robb, L.6    Harvey, R.P.7
  • 12
    • 0032907924 scopus 로고    scopus 로고
    • The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development
    • Tanaka M, Chen Z, Bartunkova S, Yamasaki N, and Izumo S: The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development 126: 1269-1280, 1999
    • (1999) Development , vol.126 , pp. 1269-1280
    • Tanaka, M.1    Chen, Z.2    Bartunkova, S.3    Yamasaki, N.4    Izumo, S.5
  • 13
    • 0031647381 scopus 로고    scopus 로고
    • Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
    • Fu Y, Yan W, Mohun TJ, and Evans SM: Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development 125: 4439-4449, 1998
    • (1998) Development , vol.125 , pp. 4439-4449
    • Fu, Y.1    Yan, W.2    Mohun, T.J.3    Evans, S.M.4
  • 15
    • 0031685432 scopus 로고    scopus 로고
    • Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice
    • Ranganayakulu G, Elliott DA, Harvey RP, and Olson EN: Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice. Development 125: 3037-3048, 1998
    • (1998) Development , vol.125 , pp. 3037-3048
    • Ranganayakulu, G.1    Elliott, D.A.2    Harvey, R.P.3    Olson, E.N.4
  • 16
    • 0034671733 scopus 로고    scopus 로고
    • The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression
    • Molkentin JD: The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem 275: 38949-38952, 2000
    • (2000) J Biol Chem , vol.275 , pp. 38949-38952
    • Molkentin, J.D.1
  • 17
    • 0030996908 scopus 로고    scopus 로고
    • Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
    • Molkentin JD, Lin Q, Duncan SA, and Olson EN: Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev 11: 1061-1072, 1997
    • (1997) Genes Dev , vol.11 , pp. 1061-1072
    • Molkentin, J.D.1    Lin, Q.2    Duncan, S.A.3    Olson, E.N.4
  • 19
    • 0033934480 scopus 로고    scopus 로고
    • Abnormalities of the genitourinary tract in female mice lacking GATA5
    • Molkentin JD, Tymitz KM, Richardson JA, and Olson EN: Abnormalities of the genitourinary tract in female mice lacking GATA5. Mol Cell Biol 20: 5256-5260, 2000
    • (2000) Mol Cell Biol , vol.20 , pp. 5256-5260
    • Molkentin, J.D.1    Tymitz, K.M.2    Richardson, J.A.3    Olson, E.N.4
  • 20
    • 0032533241 scopus 로고    scopus 로고
    • GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo
    • Morrisey EE, Tang Z, Sigrist K, Lu MM, Jiang F, Ip HS, and Parmacek MS: GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev 12: 3579-3590, 1998
    • (1998) Genes Dev , vol.12 , pp. 3579-3590
    • Morrisey, E.E.1    Tang, Z.2    Sigrist, K.3    Lu, M.M.4    Jiang, F.5    Ip, H.S.6    Parmacek, M.S.7
  • 21
    • 0032590183 scopus 로고    scopus 로고
    • The transcription factor GATA6 is essential for early extraembryonic development
    • Koutsourakis M, Langeveld A, Patient R, Beddington R, and Grosveld F: The transcription factor GATA6 is essential for early extraembryonic development. Development 126: 723-732, 1999
    • (1999) Development , vol.126 , pp. 723-732
    • Koutsourakis, M.1    Langeveld, A.2    Patient, R.3    Beddington, R.4    Grosveld, F.5
  • 23
    • 0033398273 scopus 로고    scopus 로고
    • The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila
    • Gajewski K, Fossett N, Molkentin JD, and Schulz RA: The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila. Development 126: 5679-5688, 1999
    • (1999) Development , vol.126 , pp. 5679-5688
    • Gajewski, K.1    Fossett, N.2    Molkentin, J.D.3    Schulz, R.A.4
  • 24
    • 0030799792 scopus 로고    scopus 로고
    • The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
    • Durocher D, Charron F, Warren R, Schwartz RJ, and Nemer M: The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J 16: 5687-5696, 1997
    • (1997) EMBO J , vol.16 , pp. 5687-5696
    • Durocher, D.1    Charron, F.2    Warren, R.3    Schwartz, R.J.4    Nemer, M.5
  • 25
    • 0031815073 scopus 로고    scopus 로고
    • GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: Role for regulating early cardiac gene expression
    • Sepulveda JL, Belaguli N, Nigam V, Chen CY, Nemer M, and Schwartz RJ: GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol Cell Biol 18: 3405-3415, 1998
    • (1998) Mol Cell Biol , vol.18 , pp. 3405-3415
    • Sepulveda, J.L.1    Belaguli, N.2    Nigam, V.3    Chen, C.Y.4    Nemer, M.5    Schwartz, R.J.6
  • 26
    • 0031844382 scopus 로고    scopus 로고
    • The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
    • Lee Y, Shioi T, Kasahara H, Jobe SM, Wiese RJ, Markham BE, and Izumo S: The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol Cell Biol 18: 3120-3129, 1998
    • (1998) Mol Cell Biol , vol.18 , pp. 3120-3129
    • Lee, Y.1    Shioi, T.2    Kasahara, H.3    Jobe, S.M.4    Wiese, R.J.5    Markham, B.E.6    Izumo, S.7
  • 30
    • 0031647382 scopus 로고    scopus 로고
    • A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice
    • Searcy RD, Vincent EB, Liberatore CM, and Yutzey KE: A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice. Development 125: 4461-4470, 1998
    • (1998) Development , vol.125 , pp. 4461-4470
    • Searcy, R.D.1    Vincent, E.B.2    Liberatore, C.M.3    Yutzey, K.E.4
  • 31
    • 0032937224 scopus 로고    scopus 로고
    • Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer
    • Lien CL, Wu C, Mercer B, Webb R, Richardson JA, and Olson EN: Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development 126: 75-84, 1999
    • (1999) Development , vol.126 , pp. 75-84
    • Lien, C.L.1    Wu, C.2    Mercer, B.3    Webb, R.4    Richardson, J.A.5    Olson, E.N.6
  • 32
    • 0034650305 scopus 로고    scopus 로고
    • An Nkx-dependent enhancer regulates cGATA-6 gene expression during early stages of heart development
    • Davis DL, Wessels A, and Burch JB: An Nkx-dependent enhancer regulates cGATA-6 gene expression during early stages of heart development. Dev Biol 217: 310-322, 2000
    • (2000) Dev Biol , vol.217 , pp. 310-322
    • Davis, D.L.1    Wessels, A.2    Burch, J.B.3
  • 33
    • 0034650312 scopus 로고    scopus 로고
    • Direct activation of a GATA6 cardiac enhancer by Nkx2.5: Evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart
    • Molkentin JD, Antos C, Mercer B, Taigen T, Miano JM, and Olson EN: Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart. Dev Biol 217: 301-309, 2000
    • (2000) Dev Biol , vol.217 , pp. 301-309
    • Molkentin, J.D.1    Antos, C.2    Mercer, B.3    Taigen, T.4    Miano, J.M.5    Olson, E.N.6
  • 34
    • 0028087974 scopus 로고
    • D-mef2: A Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis
    • USA
    • Nguyen HT, Bodmer R, Abmayr SM, McDermott JC, and Spoerel NA: D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis. Proc Natl Acad Sci USA 91: 7520-7524, 1994
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 7520-7524
    • Nguyen, H.T.1    Bodmer, R.2    Abmayr, S.M.3    McDermott, J.C.4    Spoerel, N.A.5
  • 35
    • 0028229168 scopus 로고
    • D-MEF2: A MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis
    • USA
    • Lilly B, Galewsky S, Firulli AB, Schulz RA, and Olson EN: D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proc Natl Acad Sci USA 91: 5662-5666, 1994
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 5662-5666
    • Lilly, B.1    Galewsky, S.2    Firulli, A.B.3    Schulz, R.A.4    Olson, E.N.5
  • 36
    • 0031033603 scopus 로고    scopus 로고
    • D-mef2 is a target for Tinman activation during Drosophila heart development
    • Gajewski K, Kim Y, Lee YM, Olson EN, and Schulz RA: D-mef2 is a target for Tinman activation during Drosophila heart development. EMBO J 16: 515-522, 1997
    • (1997) EMBO J , vol.16 , pp. 515-522
    • Gajewski, K.1    Kim, Y.2    Lee, Y.M.3    Olson, E.N.4    Schulz, R.A.5
  • 37
    • 0028917564 scopus 로고
    • Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila
    • Lilly B, Zhao B, Ranganayakulu G, Paterson BM, Schulz RA, and Olson EN: Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila. Science 267: 688-693, 1995
    • (1995) Science , vol.267 , pp. 688-693
    • Lilly, B.1    Zhao, B.2    Ranganayakulu, G.3    Paterson, B.M.4    Schulz, R.A.5    Olson, E.N.6
  • 38
    • 0030911475 scopus 로고    scopus 로고
    • Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C
    • Lin Q, Schwarz J, Bucana C, and Olson EN: Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276: 1404-1407, 1997
    • (1997) Science , vol.276 , pp. 1404-1407
    • Lin, Q.1    Schwarz, J.2    Bucana, C.3    Olson, E.N.4
  • 39
    • 0036851837 scopus 로고    scopus 로고
    • Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
    • Naya FJ, Black BL, Wu H, Bassel-Duby R, Richardson JA, Hill JA, and Olson EN: Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med 8: 1303-1309, 2002
    • (2002) Nat Med , vol.8 , pp. 1303-1309
    • Naya, F.J.1    Black, B.L.2    Wu, H.3    Bassel-Duby, R.4    Richardson, J.A.5    Hill, J.A.6    Olson, E.N.7
  • 41
    • 0037067697 scopus 로고    scopus 로고
    • Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity
    • Sepulveda JL, Vlahopoulos S, Iyer D, Belaguli N, and Schwartz RJ: Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity. J Biol Chem 277: 25775-25782, 2002
    • (2002) J Biol Chem , vol.277 , pp. 25775-25782
    • Sepulveda, J.L.1    Vlahopoulos, S.2    Iyer, D.3    Belaguli, N.4    Schwartz, R.J.5
  • 42
    • 0000634381 scopus 로고    scopus 로고
    • Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription
    • Chen CY and Schwartz RJ: Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription. Mol Cell Biol 16: 6372-6384, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 6372-6384
    • Chen, C.Y.1    Schwartz, R.J.2
  • 45
    • 0035967868 scopus 로고    scopus 로고
    • Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor
    • Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, Small E, Krieg PA, and Olson EN: Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell 105: 851-862, 2001
    • (2001) Cell , vol.105 , pp. 851-862
    • Wang, D.1    Chang, P.S.2    Wang, Z.3    Sutherland, L.4    Richardson, J.A.5    Small, E.6    Krieg, P.A.7    Olson, E.N.8
  • 48
    • 0041422285 scopus 로고    scopus 로고
    • The serum response factor coactivator myocardin is required for vascular smooth muscle development
    • USA
    • Li S, Wang DZ, Wang Z, Richardson JA, and Olson EN: The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci USA 100: 9366-9370, 2003
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 9366-9370
    • Li, S.1    Wang, D.Z.2    Wang, Z.3    Richardson, J.A.4    Olson, E.N.5
  • 50
    • 0141764868 scopus 로고    scopus 로고
    • A HANDful of questions: The molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors
    • Firulli AB: A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors. Gene 312: 27-40, 2003
    • (2003) Gene , vol.312 , pp. 27-40
    • Firulli, A.B.1
  • 51
    • 0030903857 scopus 로고    scopus 로고
    • Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
    • Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, and Olson EN: Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet 16: 154-160, 1997
    • (1997) Nat Genet , vol.16 , pp. 154-160
    • Srivastava, D.1    Thomas, T.2    Lin, Q.3    Kirby, M.L.4    Brown, D.5    Olson, E.N.6
  • 52
    • 0031882143 scopus 로고    scopus 로고
    • Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
    • Firulli AB, McFadden DG, Lin Q, Srivastava D, and Olson EN: Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet 18: 266-270, 1998
    • (1998) Nat Genet , vol.18 , pp. 266-270
    • Firulli, A.B.1    McFadden, D.G.2    Lin, Q.3    Srivastava, D.4    Olson, E.N.5
  • 53
    • 0031882249 scopus 로고    scopus 로고
    • The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
    • Riley P, Anson-Cartwright L, and Cross JC: The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis. Nat Genet 18: 271-275, 1998
    • (1998) Nat Genet , vol.18 , pp. 271-275
    • Riley, P.1    Anson-Cartwright, L.2    Cross, J.C.3
  • 54
    • 0035891429 scopus 로고    scopus 로고
    • The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation
    • Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, and Srivastava D: The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev Biol 239: 190-203, 2001
    • (2001) Dev Biol , vol.239 , pp. 190-203
    • Yamagishi, H.1    Yamagishi, C.2    Nakagawa, O.3    Harvey, R.P.4    Olson, E.N.5    Srivastava, D.6
  • 55
    • 0037025326 scopus 로고    scopus 로고
    • The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism
    • Dai YS, Cserjesi P, Markham BE, and Molkentin JD: The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism. J Biol Chem 277: 24390-24398, 2002
    • (2002) J Biol Chem , vol.277 , pp. 24390-24398
    • Dai, Y.S.1    Cserjesi, P.2    Markham, B.E.3    Molkentin, J.D.4
  • 56
    • 0036773644 scopus 로고    scopus 로고
    • The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene
    • Thattaliyath BD, Firulli BA, and Firulli AB: The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene. J Mol Cell Cardiol 34: 1335-1344, 2002
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1335-1344
    • Thattaliyath, B.D.1    Firulli, B.A.2    Firulli, A.B.3
  • 61
    • 0034931034 scopus 로고    scopus 로고
    • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
    • Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, Nagai R, and Komuro I: Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet 28: 276-280, 2001
    • (2001) Nat Genet , vol.28 , pp. 276-280
    • Hiroi, Y.1    Kudoh, S.2    Monzen, K.3    Ikeda, Y.4    Yazaki, Y.5    Nagai, R.6    Komuro, I.7
  • 62
    • 2442624606 scopus 로고    scopus 로고
    • Differential expression and function of Tbx5 and Tbx20 in cardiac development
    • Plageman TF Jr and Yutzey KE: Differential expression and function of Tbx5 and Tbx20 in cardiac development. J Biol Chem 279: 19026-19034, 2004
    • (2004) J Biol Chem , vol.279 , pp. 19026-19034
    • Plageman Jr., T.F.1    Yutzey, K.E.2
  • 67
    • 0028903248 scopus 로고
    • Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo
    • Frasch M: Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. Nature 374: 464-467, 1995
    • (1995) Nature , vol.374 , pp. 464-467
    • Frasch, M.1
  • 68
    • 0031018002 scopus 로고    scopus 로고
    • A role for bone morphogenetic proteins in the induction of cardiac myogenesis
    • Schultheiss TM, Burch JB, and Lassar AB: A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev 11: 451-462, 1997
    • (1997) Genes Dev , vol.11 , pp. 451-462
    • Schultheiss, T.M.1    Burch, J.B.2    Lassar, A.B.3
  • 71
    • 0029000929 scopus 로고
    • Heart development in Drosophila requires the segment polarity gene wingless
    • Wu X, Golden K, and Bodmer R: Heart development in Drosophila requires the segment polarity gene wingless. Dev Biol 169: 619-628, 1995
    • (1995) Dev Biol , vol.169 , pp. 619-628
    • Wu, X.1    Golden, K.2    Bodmer, R.3
  • 72
    • 0030578428 scopus 로고    scopus 로고
    • The wingless signaling pathway is directly involved in Drosophila heart development
    • Park M, Wu X, Golden K, Axelrod JD, and Bodmer R: The wingless signaling pathway is directly involved in Drosophila heart development. Dev Biol 177: 104-116, 1996
    • (1996) Dev Biol , vol.177 , pp. 104-116
    • Park, M.1    Wu, X.2    Golden, K.3    Axelrod, J.D.4    Bodmer, R.5
  • 73
    • 0035252357 scopus 로고    scopus 로고
    • Inhibition of Wnt activity induces heart formation from posterior mesoderm
    • Marvin MJ, Di Rocco G, Gardiner A, Bush SM, and Lassar AB: Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev 15: 316-327, 2001
    • (2001) Genes Dev , vol.15 , pp. 316-327
    • Marvin, M.J.1    Di Rocco, G.2    Gardiner, A.3    Bush, S.M.4    Lassar, A.B.5
  • 74
    • 0035252105 scopus 로고    scopus 로고
    • Wnt signals from the neural tube block ectopic cardiogenesis
    • Tzahor E and Lassar AB: Wnt signals from the neural tube block ectopic cardiogenesis. Genes Dev 15: 255-260, 2001
    • (2001) Genes Dev , vol.15 , pp. 255-260
    • Tzahor, E.1    Lassar, A.B.2
  • 75
    • 0035252543 scopus 로고    scopus 로고
    • Wnt antagonism initiates cardiogenesis in Xenopus laevis
    • Schneider VA and Mercola M: Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev 15: 304-315, 2001
    • (2001) Genes Dev , vol.15 , pp. 304-315
    • Schneider, V.A.1    Mercola, M.2
  • 76
    • 0037043688 scopus 로고    scopus 로고
    • Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis
    • Pandur P, Lasche M, Eisenberg LM, and Kuhl M: Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 418: 636-641, 2002
    • (2002) Nature , vol.418 , pp. 636-641
    • Pandur, P.1    Lasche, M.2    Eisenberg, L.M.3    Kuhl, M.4
  • 77
    • 0037947766 scopus 로고    scopus 로고
    • A Wnt- and beta -catenin-dependent pathway for mammalian cardiac myogenesis
    • USA
    • Nakamura T, Sano M, Songyang Z, and Schneider MD: A Wnt- and beta -catenin-dependent pathway for mammalian cardiac myogenesis. Proc Natl Acad Sci USA 100: 5834-5839, 2003
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 5834-5839
    • Nakamura, T.1    Sano, M.2    Songyang, Z.3    Schneider, M.D.4
  • 78
    • 22744440212 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling
    • Naito AT, Akazawa H, Takano H, Minamino T, Nagai T, Aburatani H, and Komuro I: Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling. Circ Res 97: 144-151, 2005
    • (2005) Circ Res , vol.97 , pp. 144-151
    • Naito, A.T.1    Akazawa, H.2    Takano, H.3    Minamino, T.4    Nagai, T.5    Aburatani, H.6    Komuro, I.7
  • 79
    • 0029845996 scopus 로고    scopus 로고
    • Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages
    • Beiman M, Shilo BZ, and Volk T: Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. Genes Dev 10: 2993-3002, 1996
    • (1996) Genes Dev , vol.10 , pp. 2993-3002
    • Beiman, M.1    Shilo, B.Z.2    Volk, T.3
  • 80
    • 0029849087 scopus 로고    scopus 로고
    • Heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo
    • Gisselbrecht S, Skeath JB, Doe CQ, and Michelson AM: heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo. Genes Dev 10: 3003-3017, 1996
    • (1996) Genes Dev , vol.10 , pp. 3003-3017
    • Gisselbrecht, S.1    Skeath, J.B.2    Doe, C.Q.3    Michelson, A.M.4
  • 81
    • 0033951035 scopus 로고    scopus 로고
    • Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar)
    • Reifers F, Walsh EC, Leger S, Stainier DY, and Brand M: Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). Development 127: 225-235, 2000
    • (2000) Development , vol.127 , pp. 225-235
    • Reifers, F.1    Walsh, E.C.2    Leger, S.3    Stainier, D.Y.4    Brand, M.5
  • 82
    • 0036333532 scopus 로고    scopus 로고
    • Regulation of avian cardiogenesis by Fgf8 signaling
    • Alsan BH and Schultheiss TM: Regulation of avian cardiogenesis by Fgf8 signaling. Development 129: 1935-1943, 2002
    • (2002) Development , vol.129 , pp. 1935-1943
    • Alsan, B.H.1    Schultheiss, T.M.2
  • 85
    • 0032975539 scopus 로고    scopus 로고
    • Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient
    • Hosoda T, Komuro I, Shiojima I, Hiroi Y, Harada M, Murakawa Y, Hirata Y, and Yazaki Y: Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient. Jpn Circ J 63: 425-426, 1999
    • (1999) Jpn Circ J , vol.63 , pp. 425-426
    • Hosoda, T.1    Komuro, I.2    Shiojima, I.3    Hiroi, Y.4    Harada, M.5    Murakawa, Y.6    Hirata, Y.7    Yazaki, Y.8
  • 86
    • 0035923555 scopus 로고    scopus 로고
    • NKX2.5 mutations in patients with tetralogy of fallot
    • Goldmuntz E, Geiger E, and Benson DW: NKX2.5 mutations in patients with tetralogy of fallot. Circulation 104: 2565-2568, 2001
    • (2001) Circulation , vol.104 , pp. 2565-2568
    • Goldmuntz, E.1    Geiger, E.2    Benson, D.W.3
  • 88
    • 0036848609 scopus 로고    scopus 로고
    • Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD
    • Watanabe Y, Benson DW, Yano S, Akagi T, Yoshino M, and Murray JC: Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD. J Med Genet 39: 807-811, 2002
    • (2002) J Med Genet , vol.39 , pp. 807-811
    • Watanabe, Y.1    Benson, D.W.2    Yano, S.3    Akagi, T.4    Yoshino, M.5    Murray, J.C.6
  • 91
    • 4444298928 scopus 로고    scopus 로고
    • Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease
    • Reamon-Buettner SM, and Borlak J: Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease. J Med Genet 41: 684-690, 2004
    • (2004) J Med Genet , vol.41 , pp. 684-690
    • Reamon-Buettner, S.M.1    Borlak, J.2


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