Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages

Genes and Development

Volumn 10, Issue 23, 1996, Pages 2993-3002

  Beiman, Merav ^a   Shilo, Ben Zion ^a   Volk, Talila ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

cell migration; Drosophila; FGF receptor; heart; mesoderm; muscles

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LINEAGE; CELL MIGRATION; CELL SPREADING; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; MESODERM; MORPHOGENESIS; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALIA;

EID: 0029845996     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.23.2993     Document Type: Article

References (42)

1. Amaya, E., T.J. Musci, and M.W. Kirschner. 1991. Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66: 257-270.
2. Azpiazu, N. and M. Frasch. 1993. tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes & Dev. 7: 1325-1340.
3. Bate, M. 1990. The embryonic development of larval muscles in Drosophila. Development 110: 791-804.
4. Bate, M. and E. Rushton. 1993. Myogenesis and muscle patterning in Drosophila. C.R. Acad. Sci. III 316: 1047-1061.
5. Baylies, M.K., A. Martinez-Arias, and M. Bate. 1995. wingless is required for the formation of a subset of muscle founder cells during Drosophila embryogenesis. Development 121: 3829-3837.
6. Beer, J., G. Technau, and J. Campos-Ortega. 1987. Lineage analysis of transplanted individual cells in embryos of Drosophila melanogaster. IV. Commitment and proliferative capabilities of individual mesodermal cells. Roux's Arch. Dev. Biol. 196: 222-230.
7. Bellen, H.J., H. Vaessin, E. Bier, A. Kolodkin, D. D'Evelyn, S. Kooyer, and Y.N. Jan. 1992. The Drosophila couch potato gene: An essential gene required for normal adult behavior. Genetics 131: 365-375.
8. Boulay, J.L., C. Dennefeld, and A. Alberga. 1987. The Drosophila developmental gene snail encodes a protein with nucleic acid binding fingers. Nature 330: 395-398.
9. Bour, B.A., M.A. O'Brien, W.L. Lockwood, E.S. Goldstein, R. Bodmer, P.H. Taghert, S.M. Abmayr, and H.T. Nguyen. 1995. Drosophila MEF2, a transcription factor that is essential for myogenesis. Genes & Dev. 9: 730-741.
10. Brand, A.H. and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
11. Corbin, V., A.M. Michelson, S.M. Abmayr, V. Neel, E. Alcamo, T. Maniatis, and M.W. Young. 1991. A role for the Droso- phila neurogenic genes in mesoderm differentiation. Cell 67: 311-323.
12. Deng, C.-X., A. Wynshaw-Boris, M.M. Shen, C. Daugherty, D.M. Ornitz, and P. Leder. 1994. Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes & Dev. 8: 3045-3057.
13. DeVore, D.L., H.R. Horovitz, and M.J. Stern. 1995. An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites. Cell 83: 611-620.
14. Frasch, M. 1995. Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. Nature 374: 464-467.
15. Frommer, G., G. Vorbruggen, G. Pasca, H. Jackle, and T. Volk. 1996. Epidermal egr-like zinc finger protein of Drosophila participates in myotube guidance. EMBO J. 15: 1642-1649.
16. Glazer, L. and B.-Z. Shilo. 1991. The Drosophila FGF receptor homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension. Genes & Dev. 5: 697-705.
17. Hoshizaki, D.K., T. Blackburn, C. Price, M. Ghosh, K. Miles, M. Ragucci, and R. Sweis. 1994. Embryonic fat-cell lineage in Drosophila melanogaster. Development 120: 2489-2499.
18. Ip, Y.T., R.E. Park, D. Kosman, K. Yazdanbakhsh, and M. Levine. 1992. dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo. Genes & Dev. 6: 1518-1530.
19. Isaacs, H.V., M.E. Pownall, and J.M. Slack. 1994. eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13: 4469-4481.
20. Ito, M., T. Matsui, T. Taniguchi, and K. Chihara. 1994. Alternative splicing generates two distinct transcripts for the Drosophila melanogaster fibroblast growth factor receptor homolog. Gene 139: 215-218.
21. Jiang, J., D. Kosman, Y.T. Ip, and M. Levine. 1991. The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes & Dev. 5: 1881-1891.
22. Klämbt, C., L. Glazer, and B.-Z. Shilo. 1992. breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cellls. Genes & Dev. 6: 1668-1678.
23. Lawrence, P.A., R. Bodmer, and J.P. Vincent. 1995. Segmental patterning of heart precursors in Drosophila. Development 121: 4303-4308.
24. Leptin, M. 1991. twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes & Dev. 5: 1568-1576.
25. Lilly, B., S. Galewsky, A.B. Firulli, R.A. Schulz, and E.N. Olson. 1994. D-MEF2: A MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proc. Natl. Acad. Sci. 91: 5662-5666.
26. Murphy, A.M., T. Lee, C.M. Andrews, B-Z. Shilo, and D.J. Montell. 1995. The breathless FGF receptor homolog, a downstream target of Drosophila C/EBP in the developmental control of cell migration. Development 121: 2255-2263.
27. Murre, C., P.S. McCaw, and D. Baltimore. 1989. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD and myc proteins. Cell 56: 777-783.
28. Nambu, J.R., R.G. Franks, S. Hu, and S.T. Crews. 1990. The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells. Cell 63: 63-75.
29. Park, M.Y., X.S. Wu, K. Golden, J.D. Axelrod, and R. Bodmer. 1996. The wingless signaling pathway is directly involved in Drosophila heart development. Dev. Biol. 177: 104-116.
30. Patel, N.H., P.M. Snow, and C.S. Goodman. 1987. Characterization and cloning of fasciclin III: A glycoprotein expressed on a subset of neurons and axon pathways in Drosophila. Cell 48: 975-988.
31. Rao, Y., H. Vaessin, L.Y. Jan, and Y.N. Jan. 1991. Neuroectoderm in Drosophila embryos is dependent on the mesoderm for positioning but not for formation. Genes & Dev. 5: 1577-1588.
32. Reichman-Fried, M. and B-Z. Shilo. 1995. Breathless, a Drosophila FGF receptor homolog, is required for the onset of tracheal cell migration and tracheole formation. Mech. Dev. 52: 265-273.
33. Reichman-Fried, M., B. Dickson, E. Hafen, and B-Z. Shilo. 1994. Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Genes & Dev. 8: 428-439.
34. Robinson, M.L., L.A. MacMillan-Crow, J.A. Thompson, and P.A. Overbeek. 1995. Expression of a truncated FGF receptor results in defective lens development in transgenic mice. Development 121: 3959-3967.
35. Shishido, E., S.-I. Higashijima, Y. Emori, and K. Saigo. 1993. Two FGF-receptor homologs of Drosophila: One is expressed in mesodermal primordium in early embryos. Development 117: 751-761.
36. St. Johnston, D. and C. Nüsslein-Volhard. 1992. The origin of pattern and polarity in the Drosophila embryo. Cell 68: 201-219.
37. Staehling-Hampton, K., F.M. Hoffmann, M.K. Baylies, E. Rushton, and M. Bate. 1994. dpp induces mesodermal gene expression in Drosophila. Nature 372: 783-786.
38. Thisse, B., C. Stoetzel, T.C. Gorostiza, and S.F. Perrin. 1988. Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos. EMBO J. 7: 2175-2183.
39. Volk, T. and K. VijayRaghavan. 1994. A central role for epidermal segment border cells in the induction of muscle patterning in the Drosophila embryo. Development 120: 59-70.
40. Yamaguchi, T.P., K. Harpal, M. Henkemeyer, and J. Rossant. 1994. fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes & Dev. 8: 3032-3044.
41. Yarnitzky, T. and T. Volk. 1995. Laminin is required for heart, somatic muscles, and gut development in the Drosophila embryo. Dev. Biol. 169: 609-618.
42. Zaffran, S., M. Astier, D. Gratecos, A. Guillen, and M. Sémériva. 1995. Cellular interactions during heart morphogenesis in the Drosophila embryo. Biol. Cell 84: 13-24.