메뉴 건너뛰기




Volumn 312, Issue 1-2, 2003, Pages 27-40

A HANDful of questions: The molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors

Author keywords

Basic helix loop helix proteins; Embryonic development; Heart and neural crest derivatives (HAND) factors; Transcription

Indexed keywords

AMINO ACID; HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; HAND2 PROTEIN, HUMAN; HAND2 PROTEIN, ZEBRAFISH; HELIX LOOP HELIX PROTEIN, EHAND; HELIX-LOOP-HELIX PROTEIN, EHAND; ZEBRAFISH PROTEIN;

EID: 0141764868     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(03)00669-3     Document Type: Review
Times cited : (93)

References (64)
  • 1
    • 0036912349 scopus 로고    scopus 로고
    • Tooth-type specific expression of dhand/HAND2: Possible involvement in murine lower incisor morphogenesis
    • Abe M., Tamamura Y., Yamagishi H., et al. Tooth-type specific expression of dhand/HAND2: possible involvement in murine lower incisor morphogenesis. Cell Tissue Res. 310:2002;201-212.
    • (2002) Cell Tissue Res. , vol.310 , pp. 201-212
    • Abe, M.1    Tamamura, Y.2    Yamagishi, H.3
  • 2
    • 0034234675 scopus 로고    scopus 로고
    • Conservation of sequence and expression of xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development
    • Angelo S., Lohr J., Lee K.H., Ticho B.S., Breitbart R.E., Hill S., Yost H.J., Srivastava D. Conservation of sequence and expression of xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development. Mech. Dev. 95:2000;231-237.
    • (2000) Mech. Dev. , vol.95 , pp. 231-237
    • Angelo, S.1    Lohr, J.2    Lee, K.H.3    Ticho, B.S.4    Breitbart, R.E.5    Hill, S.6    Yost, H.J.7    Srivastava, D.8
  • 3
    • 13044287363 scopus 로고    scopus 로고
    • Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations
    • Basson C.T., Huang T., Lin R.C., et al. Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations. Proc. Natl. Acad. Sci. USA. 96:1999;2919-2924.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2919-2924
    • Basson, C.T.1    Huang, T.2    Lin, R.C.3
  • 4
    • 0028575413 scopus 로고
    • An intermolecular disulfide bond stabilizes E2A homodimers and is required for DNA binding at physiological temperatures
    • Benezra R. An intermolecular disulfide bond stabilizes E2A homodimers and is required for DNA binding at physiological temperatures. Cell. 79:1994;1057-1067.
    • (1994) Cell , vol.79 , pp. 1057-1067
    • Benezra, R.1
  • 6
    • 0034650311 scopus 로고    scopus 로고
    • Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand
    • Bruneau B.G., Bao Z.Z., Tanaka M., et al. Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand. Dev. Biol. 217:2000;266-277.
    • (2000) Dev. Biol. , vol.217 , pp. 266-277
    • Bruneau, B.G.1    Bao, Z.Z.2    Tanaka, M.3
  • 7
    • 0031964117 scopus 로고    scopus 로고
    • Expression profile of gli family members and shh in normal and mutant mouse limb development
    • Buscher D., Ruther U. Expression profile of gli family members and shh in normal and mutant mouse limb development. Dev. Dynamics. 211:1998;88-96.
    • (1998) Dev. Dynamics , vol.211 , pp. 88-96
    • Buscher, D.1    Ruther, U.2
  • 8
    • 0034846639 scopus 로고    scopus 로고
    • Dimerization partners determine the activity of the Twist bHLH protein during Drosophila mesoderm development
    • Castanon I., Von stetina S., Kass J., Baylies M.K. Dimerization partners determine the activity of the Twist bHLH protein during Drosophila mesoderm development. Development. 128:2001;3145-3159.
    • (2001) Development , vol.128 , pp. 3145-3159
    • Castanon, I.1    Von Stetina, S.2    Kass, J.3    Baylies, M.K.4
  • 9
    • 0037012509 scopus 로고    scopus 로고
    • A twist in fate: Evolutionary comparison of twist structure and function
    • Castanon I., Baylies M.K. A twist in fate: evolutionary comparison of twist structure and function. Gene. 287:2002;11-22.
    • (2002) Gene , vol.287 , pp. 11-22
    • Castanon, I.1    Baylies, M.K.2
  • 10
    • 0035889235 scopus 로고    scopus 로고
    • Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer
    • Charite J., McFadden D.G., Merlo G., et al. Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer. Genes Dev. 15:2001;3039-3049.
    • (2001) Genes Dev. , vol.15 , pp. 3039-3049
    • Charite, J.1    McFadden, D.G.2    Merlo, G.3
  • 11
    • 0034043442 scopus 로고    scopus 로고
    • The bHLH factor dHAND controls sonic hedgehog expression and establishment of the zone of polarizing activity during limb development
    • Charite J., Mcfadden D.G., Olson E.N. The bHLH factor dHAND controls sonic hedgehog expression and establishment of the zone of polarizing activity during limb development. Development. 127:2000;2461-2470.
    • (2000) Development , vol.127 , pp. 2461-2470
    • Charite, J.1    Mcfadden, D.G.2    Olson, E.N.3
  • 12
    • 0032848185 scopus 로고    scopus 로고
    • Combinatorial gene regulation by eukaryotic transcription factors
    • Chen L. Combinatorial gene regulation by eukaryotic transcription factors. Curr. Opin. Struct. Biol. 9:1999;48-55.
    • (1999) Curr. Opin. Struct. Biol. , vol.9 , pp. 48-55
    • Chen, L.1
  • 13
    • 0034500793 scopus 로고    scopus 로고
    • Genetic insights into trophoblast differentiation and placental morphogenesis
    • Cross J.C. Genetic insights into trophoblast differentiation and placental morphogenesis. Semin. Cell Dev. Biol. 11:2000;105-113.
    • (2000) Semin. Cell Dev. Biol. , vol.11 , pp. 105-113
    • Cross, J.C.1
  • 14
    • 0029046701 scopus 로고
    • Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development
    • Cross J.C., Flannery M.L., Blanar M.A., et al. Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development. Development. 121:1995;2513-2523.
    • (1995) Development , vol.121 , pp. 2513-2523
    • Cross, J.C.1    Flannery, M.L.2    Blanar, M.A.3
  • 15
    • 0029142976 scopus 로고
    • Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development
    • Cserjesi P., Brown D., Lyons G.E., Olson E.N. Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. Dev. Biol. 170:1995;664-678.
    • (1995) Dev. Biol. , vol.170 , pp. 664-678
    • Cserjesi, P.1    Brown, D.2    Lyons, G.E.3    Olson, E.N.4
  • 16
    • 0037066685 scopus 로고    scopus 로고
    • The basic helix-loop-helix factor HAND2 functions as a transcriptional activator by binding to E-boxes as a heterodimer
    • Dai Y.S., Cserjesi P. The basic helix-loop-helix factor HAND2 functions as a transcriptional activator by binding to E-boxes as a heterodimer. J. Biol. Chem. 277:2002;12604-12612.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12604-12612
    • Dai, Y.S.1    Cserjesi, P.2
  • 17
    • 0037025326 scopus 로고    scopus 로고
    • The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism
    • Dai Y.S., Cserjesi P., Markham B.E., Molkentin J.D. The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism. J. Biol. Chem. 277:2002;24390-24398.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24390-24398
    • Dai, Y.S.1    Cserjesi, P.2    Markham, B.E.3    Molkentin, J.D.4
  • 18
    • 0034130648 scopus 로고    scopus 로고
    • Role of dHAND in the anterior-posterior polarization of the limb bud: Implications for the sonic hedgehog pathway
    • Fernandez-Teran M., Piedra M.E., Kathiriya I.S., Srivastava D., Rodriguez-Rey J.C., Ros M.A. Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the sonic hedgehog pathway. Development. 127:2000;2133-2142.
    • (2000) Development , vol.127 , pp. 2133-2142
    • Fernandez-Teran, M.1    Piedra, M.E.2    Kathiriya, I.S.3    Srivastava, D.4    Rodriguez-Rey, J.C.5    Ros, M.A.6
  • 19
    • 0036194171 scopus 로고    scopus 로고
    • Transcription factors in cardiogenesis: The combinations that may unlock the mysteries of the heart
    • Firulli A.B., Thattaliyath B.D. Transcription factors in cardiogenesis: The combinations that may unlock the mysteries of the heart. Inter. Rev. Cytol. 214:2002;1-62.
    • (2002) Inter. Rev. Cytol. , vol.214 , pp. 1-62
    • Firulli, A.B.1    Thattaliyath, B.D.2
  • 20
    • 0031882143 scopus 로고    scopus 로고
    • Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
    • Firulli A.B., McFadden D.G., Lin Q., Srivastava D., Olson E.N. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat. Genet. 18:1998;266-270.
    • (1998) Nat. Genet. , vol.18 , pp. 266-270
    • Firulli, A.B.1    McFadden, D.G.2    Lin, Q.3    Srivastava, D.4    Olson, E.N.5
  • 21
    • 0034721779 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function
    • Firulli B.A., Hadzic D.B., McDaid J.R., Firulli A.B. The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function. J. Biol. Chem. 275:2000;33567-33573.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33567-33573
    • Firulli, B.A.1    Hadzic, D.B.2    McDaid, J.R.3    Firulli, A.B.4
  • 22
    • 0029018708 scopus 로고
    • Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system
    • Hollenberg S.M., Sternglanz R., Cheng P.F., Weintraub H. Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell Biol. 15:1995;3813-3822.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3813-3822
    • Hollenberg, S.M.1    Sternglanz, R.2    Cheng, P.F.3    Weintraub, H.4
  • 23
    • 0033230089 scopus 로고    scopus 로고
    • Expression of HAND gene products may be sufficient for the differentiation of avian neural crest-derived cells into catecholaminergic neurons in culture
    • Howard M., Foster D.N., Cserjesi P. Expression of HAND gene products may be sufficient for the differentiation of avian neural crest-derived cells into catecholaminergic neurons in culture. Dev. Biol. 215:1999;62-77.
    • (1999) Dev. Biol. , vol.215 , pp. 62-77
    • Howard, M.1    Foster, D.N.2    Cserjesi, P.3
  • 24
    • 0033792535 scopus 로고    scopus 로고
    • The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification
    • Howard M.J., Stanke M., Schneider C., Wu X., Rohrer H. The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification. Development. 127:2000;4073-4081.
    • (2000) Development , vol.127 , pp. 4073-4081
    • Howard, M.J.1    Stanke, M.2    Schneider, C.3    Wu, X.4    Rohrer, H.5
  • 25
    • 0032509432 scopus 로고    scopus 로고
    • Molecular cloning of the human Hand1 gene/cDNA and its tissue restricted expression in cytotrophoblastic cells and heart
    • Knöfler M., Meinhardt G., Vasicek R., Husslein P., Egarter C. Molecular cloning of the human Hand1 gene/cDNA and its tissue restricted expression in cytotrophoblastic cells and heart. Gene. 224:1998;77-86.
    • (1998) Gene , vol.224 , pp. 77-86
    • Knöfler, M.1    Meinhardt, G.2    Vasicek, R.3    Husslein, P.4    Egarter, C.5
  • 26
    • 0036471197 scopus 로고    scopus 로고
    • Human Hand1 basic helix-loop-helix (bHLH) protein: Extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains
    • Knöfler M., Meinhardt G., Bauer S., Loregger T., Vasicek R., Bloor D.J., Kimber S.J., Husslein P. Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains. Biochem. J. 361:2002;641-651.
    • (2002) Biochem. J. , vol.361 , pp. 641-651
    • Knöfler, M.1    Meinhardt, G.2    Bauer, S.3    Loregger, T.4    Vasicek, R.5    Bloor, D.J.6    Kimber, S.J.7    Husslein, P.8
  • 27
    • 0036941646 scopus 로고    scopus 로고
    • The highly conserved cardiogenic bHLH factor HAND is specifically expressed in circular visceral muscle progenitor cells and in all cell types of the dorsal vessel during Drosophila embryogenesis
    • Kölsch V., Pauluat A. The highly conserved cardiogenic bHLH factor HAND is specifically expressed in circular visceral muscle progenitor cells and in all cell types of the dorsal vessel during Drosophila embryogenesis. Dev. Gen. Evol. 212:2002;473-485.
    • (2002) Dev. Gen. Evol. , vol.212 , pp. 473-485
    • Kölsch, V.1    Pauluat, A.2
  • 29
    • 0035001937 scopus 로고    scopus 로고
    • The Basic Helix-loop-helix Protein Family: Comparative Genomics and Phylogenetic Analysis
    • Ledent V., Vervoort M. The Basic Helix-loop-helix Protein Family: Comparative Genomics and Phylogenetic Analysis. Genome Res. 11:2001;754-770.
    • (2001) Genome Res. , vol.11 , pp. 754-770
    • Ledent, V.1    Vervoort, M.2
  • 30
    • 0033553425 scopus 로고    scopus 로고
    • Combinatorial Interactions regulate cardiac expression of the murine adenylosuccinate synthetase 1 gene
    • Lewis A.L., Xia Y., Datta S.K., McMillin J., Kellems R.E. Combinatorial Interactions regulate cardiac expression of the murine adenylosuccinate synthetase 1 gene. J. Biol. Chem. 274:1999;14188-14197.
    • (1999) J. Biol. Chem. , vol.274 , pp. 14188-14197
    • Lewis, A.L.1    Xia, Y.2    Datta, S.K.3    McMillin, J.4    Kellems, R.E.5
  • 31
    • 0026756149 scopus 로고
    • Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins
    • Li L., Heller-Harrison R., Czech M., Olson E.N. Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins. Mol. Cell Biol. 12:1992;4478-4485.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 4478-4485
    • Li, L.1    Heller-Harrison, R.2    Czech, M.3    Olson, E.N.4
  • 32
    • 0027049533 scopus 로고
    • FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains
    • Li L., Zhou J., James G., Heller-Harrison R., Czech M.P., Olson E.N. FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains. Cell. 71:1992;1181-1194.
    • (1992) Cell , vol.71 , pp. 1181-1194
    • Li, L.1    Zhou, J.2    James, G.3    Heller-Harrison, R.4    Czech, M.P.5    Olson, E.N.6
  • 33
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
    • Lyons I., Parsons L.M., Hartley L., Li R., Andrews J.E., Robb L., Harvey R.P. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev. 9:1995;1654-1666.
    • (1995) Genes Dev. , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5    Robb, L.6    Harvey, R.P.7
  • 34
    • 0033534719 scopus 로고    scopus 로고
    • Two isoforms of protein disulfide isomerase alter the dimerization status of E2A proteins by a redox mechanism
    • Markus M., Benezra R. Two isoforms of protein disulfide isomerase alter the dimerization status of E2A proteins by a redox mechanism. J. Biol. Chem. 274:1999;1040-1049.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1040-1049
    • Markus, M.1    Benezra, R.2
  • 35
    • 0033980393 scopus 로고    scopus 로고
    • Helix-loop-helix Proteins: Regulators of Transcription in Eucaryotic Organisms
    • Massari M.E., Murre C. Helix-loop-helix Proteins: Regulators of Transcription in Eucaryotic Organisms. Mol. Cell. Biol. 20:2000;429-440.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 429-440
    • Massari, M.E.1    Murre, C.2
  • 36
    • 0034523355 scopus 로고    scopus 로고
    • A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart
    • McFadden D.G., Charite J., Richardson J.A., Srivastava D., Firulli A.B., Olson E.N. A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart. Development. 127:2000;5331-5341.
    • (2000) Development , vol.127 , pp. 5331-5341
    • McFadden, D.G.1    Charite, J.2    Richardson, J.A.3    Srivastava, D.4    Firulli, A.B.5    Olson, E.N.6
  • 37
    • 0036340168 scopus 로고    scopus 로고
    • Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding
    • McFadden D.G., McAnally J., Richardson J.A., Charite' J., Olson E.N. Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding. Development. 129:2002;3077-3088.
    • (2002) Development , vol.129 , pp. 3077-3088
    • McFadden, D.G.1    McAnally, J.2    Richardson, J.A.3    Charite, J.4    Olson, E.N.5
  • 38
    • 0033832162 scopus 로고    scopus 로고
    • Sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development
    • Miller C.T., Schilling T.F., Lee K., Parker J., Kimmel C.B. sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development. Development. 127:2000;3815-3828.
    • (2000) Development , vol.127 , pp. 3815-3828
    • Miller, C.T.1    Schilling, T.F.2    Lee, K.3    Parker, J.4    Kimmel, C.B.5
  • 40
    • 0034641745 scopus 로고    scopus 로고
    • A genomewide survey of basic helix-loop-helix factors in Drosophila
    • Moore A.W., Barbel S., Jan L.Y., Jan Y.N. A genomewide survey of basic helix-loop-helix factors in Drosophila. Proc. Nat. Acad. Sci. USA. 97:2000;10436-10441.
    • (2000) Proc. Nat. Acad. Sci. USA , vol.97 , pp. 10436-10441
    • Moore, A.W.1    Barbel, S.2    Jan, L.Y.3    Jan, Y.N.4
  • 42
    • 0030043669 scopus 로고    scopus 로고
    • Molecular pathways controlling heart development
    • Olson E.N., Srivastava D. Molecular pathways controlling heart development. Science. 272:1996;671-676.
    • (1996) Science , vol.272 , pp. 671-676
    • Olson, E.N.1    Srivastava, D.2
  • 43
    • 0036369030 scopus 로고    scopus 로고
    • Twist functions in mouse development
    • O'Rourke M.P., Tam P.P. Twist functions in mouse development. Int. J. Dev. Biol. 46:2002;401-413.
    • (2002) Int. J. Dev. Biol. , vol.46 , pp. 401-413
    • O'Rourke, M.P.1    Tam, P.P.2
  • 44
    • 0036059099 scopus 로고    scopus 로고
    • Twist plays an essential role in FGF and SHH signal transduction during mouse limb development
    • O'Rourke M.P., Soo K., Behringer R.R., Hui C., Tam P.P.L. Twist plays an essential role in FGF and SHH signal transduction during mouse limb development. Dev. Biol. 248:2002;143-156.
    • (2002) Dev. Biol. , vol.248 , pp. 143-156
    • O'Rourke, M.P.1    Soo, K.2    Behringer, R.R.3    Hui, C.4    Tam, P.P.L.5
  • 45
    • 0033642275 scopus 로고    scopus 로고
    • Trophoblast Differentiation: An in Vitro model for trophoblast giant cell development
    • R.S. Tuan, & C.W. Lo. Totowa, NJ: Humana Press
    • Peters T.J., Chapman B.M., Soares M.J. Trophoblast Differentiation: An in Vitro model for trophoblast giant cell development. Tuan R.S., Lo C.W. Developmental Biology Protocols. 2000;301-311 Humana Press, Totowa, NJ.
    • (2000) Developmental Biology Protocols , pp. 301-311
    • Peters, T.J.1    Chapman, B.M.2    Soares, M.J.3
  • 46
    • 0034967571 scopus 로고    scopus 로고
    • New members of the Drosophila Myc transcription factor subfamily revealed by a genome-wide examination for basic helix-loop-helix genes
    • Peyrefitte S., Kahn D., Haenlin M. New members of the Drosophila Myc transcription factor subfamily revealed by a genome-wide examination for basic helix-loop-helix genes. Mech. Dev. 104:2001;99-104.
    • (2001) Mech. Dev. , vol.104 , pp. 99-104
    • Peyrefitte, S.1    Kahn, D.2    Haenlin, M.3
  • 47
    • 0031882249 scopus 로고    scopus 로고
    • The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
    • Riley P., Anson-Cartwright L., Cross J.C. The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis. Nat. Genet. 18:1998;271-275.
    • (1998) Nat. Genet. , vol.18 , pp. 271-275
    • Riley, P.1    Anson-Cartwright, L.2    Cross, J.C.3
  • 49
    • 0033970935 scopus 로고    scopus 로고
    • The HAND1 basic helix-loop-helix transcription factor regulates trophobblast differentiation via multiple mechanisms
    • Scott I.C., Anson-Cartwright L., RIiley P., Reda D., Cross J.C. The HAND1 basic helix-loop-helix transcription factor regulates trophobblast differentiation via multiple mechanisms. Mol. Cell. Biol. 20:2000;530-541.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 530-541
    • Scott, I.C.1    Anson-Cartwright, L.2    Riiley, P.3    Reda, D.4    Cross, J.C.5
  • 50
    • 0032007716 scopus 로고    scopus 로고
    • Xenopus eHAND: A marker for the developing cardiovascular system of the embryo that is regulated by bone morphogenetic proteins
    • Sparrow D.B., Kotecha S., Towers N., Mohun T.J. Xenopus eHAND: a marker for the developing cardiovascular system of the embryo that is regulated by bone morphogenetic proteins. Mech. Dev. 71:1998;151-163.
    • (1998) Mech. Dev. , vol.71 , pp. 151-163
    • Sparrow, D.B.1    Kotecha, S.2    Towers, N.3    Mohun, T.J.4
  • 51
    • 0029549692 scopus 로고
    • A subclass of bHLH proteins required for cardiac morphogenesis
    • Srivastava D., Cserjesi P., Olson E.N. A subclass of bHLH proteins required for cardiac morphogenesis. Science. 270:1995;1995-1999.
    • (1995) Science , vol.270 , pp. 1995-1999
    • Srivastava, D.1    Cserjesi, P.2    Olson, E.N.3
  • 52
    • 0030903857 scopus 로고    scopus 로고
    • Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
    • Srivastava D., Thomas T., Lin Q., Kirby M.L., Brown D., Olson E.N. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 16:1997;154-160.
    • (1997) Nat. Genet. , vol.16 , pp. 154-160
    • Srivastava, D.1    Thomas, T.2    Lin, Q.3    Kirby, M.L.4    Brown, D.5    Olson, E.N.6
  • 53
    • 0036773644 scopus 로고    scopus 로고
    • The Basic-Helix-loop-helix Transcription Factor HAND2 Directly Regulates Transcription of the Atrial Naturetic Peptide Gene
    • Thattaliyath B.D., B A., F., Firulli A.B. The Basic-Helix-loop-helix Transcription Factor HAND2 Directly Regulates Transcription of the Atrial Naturetic Peptide Gene. J. Mol. Cell. Cardiol. 34:2002;1325-1344.
    • (2002) J. Mol. Cell. Cardiol. , vol.34 , pp. 1325-1344
    • Thattaliyath, B.D.B.A.F.1    Firulli, A.B.2
  • 55
    • 0031695316 scopus 로고    scopus 로고
    • A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme
    • Thomas T., Kurihara H., Yamagishi H., Kurihara Y., Yazaki Y., Olson E.N., Srivastava D. A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development. 125:1998;3005-3014.
    • (1998) Development , vol.125 , pp. 3005-3014
    • Thomas, T.1    Kurihara, H.2    Yamagishi, H.3    Kurihara, Y.4    Yazaki, Y.5    Olson, E.N.6    Srivastava, D.7
  • 56
    • 0037413704 scopus 로고    scopus 로고
    • Expression of the human Hand1 gene in trophoblastic cells is transcriptionally regulated by activating and repressing specificity protein (Sp)-elements
    • Vasicek R., Meinhardt G., Haidweger E., Rotheneder H., Husslein P., Knöfler M. Expression of the human Hand1 gene in trophoblastic cells is transcriptionally regulated by activating and repressing specificity protein (Sp)-elements. Gene. 302:2003;115-127.
    • (2003) Gene , vol.302 , pp. 115-127
    • Vasicek, R.1    Meinhardt, G.2    Haidweger, E.3    Rotheneder, H.4    Husslein, P.5    Knöfler, M.6
  • 58
    • 0036424135 scopus 로고    scopus 로고
    • Transcripts encoding HAND genes are differentially expressed and regulated by BMP4 and GDNF in developing avian gut
    • Wu X., Howard M.J. Transcripts encoding HAND genes are differentially expressed and regulated by BMP4 and GDNF in developing avian gut. Gene Expression. 10:2002;279-293.
    • (2002) Gene Expression , vol.10 , pp. 279-293
    • Wu, X.1    Howard, M.J.2
  • 60
    • 0033968447 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor, dHAND, is required for vascular development
    • Yamagishi H., Olson E.N., Srivastava D. The basic helix-loop-helix transcription factor, dHAND, is required for vascular development. J. Clin. Invest. 105:2000;261-270.
    • (2000) J. Clin. Invest. , vol.105 , pp. 261-270
    • Yamagishi, H.1    Olson, E.N.2    Srivastava, D.3
  • 61
    • 0035891429 scopus 로고    scopus 로고
    • The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation
    • Yamagishi H., Yamsgishi C., Nakagawa O., Harvey R.P., Olson E.N., Srivastava D. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev. Biol. 239:2001;190-203.
    • (2001) Dev. Biol. , vol.239 , pp. 190-203
    • Yamagishi, H.1    Yamsgishi, C.2    Nakagawa, O.3    Harvey, R.P.4    Olson, E.N.5    Srivastava, D.6
  • 62
    • 0037349438 scopus 로고    scopus 로고
    • Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development
    • Yanagisawa H., Clouthier D.E., Richardson J.A., Charite J., Olson E.N. Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development. Development. 130:2003;1069-1078.
    • (2003) Development , vol.130 , pp. 1069-1078
    • Yanagisawa, H.1    Clouthier, D.E.2    Richardson, J.A.3    Charite, J.4    Olson, E.N.5
  • 63
    • 0033947661 scopus 로고    scopus 로고
    • The bHLH transcription factor HAND2 plays parallel roles in zebrafish heart and pectoral fin development
    • Yelon D., Ticho B., Halpern M.E., Ruvinsky I., Ho R.K., Silver L.M., Stainier D.Y.R. The bHLH transcription factor HAND2 plays parallel roles in zebrafish heart and pectoral fin development. Development. 127:2000;2573-2582.
    • (2000) Development , vol.127 , pp. 2573-2582
    • Yelon, D.1    Ticho, B.2    Halpern, M.E.3    Ruvinsky, I.4    Ho, R.K.5    Silver, L.M.6    Stainier, D.Y.R.7
  • 64
    • 0036011241 scopus 로고    scopus 로고
    • Mouse twist is required for fibroblast growth factor-mediated epithelial-mesenchmal signaling can cell survival during limb morphogensis
    • Zuniga A., Quillet R., Perrin-Schmitt F., Zeller R. Mouse twist is required for fibroblast growth factor-mediated epithelial-mesenchmal signaling can cell survival during limb morphogensis. Mech. Dev. 114:2002;51-59.
    • (2002) Mech. Dev. , vol.114 , pp. 51-59
    • Zuniga, A.1    Quillet, R.2    Perrin-Schmitt, F.3    Zeller, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.