-
1
-
-
4344600507
-
Hepcidin in iron metabolism
-
Ganz T. Hepcidin in iron metabolism. Curr Opin Hematol 11 (2004) 251-254
-
(2004)
Curr Opin Hematol
, vol.11
, pp. 251-254
-
-
Ganz, T.1
-
2
-
-
2042546096
-
Balancing acts: molecular control of mammalian iron metabolism
-
Hentze M.W., Muckenthaler M.U., and Andrews N.C. Balancing acts: molecular control of mammalian iron metabolism. Cell 117 (2004) 285-297
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
3
-
-
14644407428
-
Advances in understanding the molecular basis for the regulation of dietary iron absorption
-
Fleming R.E. Advances in understanding the molecular basis for the regulation of dietary iron absorption. Curr Opin Gastroenterol 21 (2005) 201-206
-
(2005)
Curr Opin Gastroenterol
, vol.21
, pp. 201-206
-
-
Fleming, R.E.1
-
4
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E., Tuttle M.S., Powelson J., Vaughn M.B., Donovan A., Ward D.M., et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306 (2004) 2090-2093
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
-
5
-
-
21144435281
-
The molecular basis of ferroportin-linked hemochromatosis
-
De Domenico I., Ward D.M., Nemeth E., Vaughn M.B., Musci G., Ganz T., et al. The molecular basis of ferroportin-linked hemochromatosis. Proc Natl Acad Sci USA 102 (2005) 8955-8960
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8955-8960
-
-
De Domenico, I.1
Ward, D.M.2
Nemeth, E.3
Vaughn, M.B.4
Musci, G.5
Ganz, T.6
-
6
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G., Chauvet C., Viatte L., Danan J.L., Bigard X., Devaux I., et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 110 (2002) 1037-1044
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
Danan, J.L.4
Bigard, X.5
Devaux, I.6
-
7
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C., Ilyin G., Courselaud B., Leroyer P., Turlin B., Brissot P., et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 276 (2001) 7811-7819
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
Leroyer, P.4
Turlin, B.5
Brissot, P.6
-
8
-
-
13844307889
-
Regulation of hepcidin transcription by interleukin-1 and interleukin-6
-
Lee P., Peng H., Gelbart T., Wang L., and Beutler E. Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc Natl Acad Sci USA 102 (2005) 1906-1910
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1906-1910
-
-
Lee, P.1
Peng, H.2
Gelbart, T.3
Wang, L.4
Beutler, E.5
-
9
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E., Rivera S., Gabayan V., Keller C., Taudorf S., Pedersen B.K., et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113 (2004) 1271-1276
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
Keller, C.4
Taudorf, S.5
Pedersen, B.K.6
-
10
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A., Papanikolaou G., Politou M., Alberti F., Girelli D., Christakis J., et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 33 (2003) 21-22
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
Alberti, F.4
Girelli, D.5
Christakis, J.6
-
11
-
-
2542560427
-
Hereditary hemochromatosis-a new look at an old disease
-
Pietrangelo A. Hereditary hemochromatosis-a new look at an old disease. N Engl J Med 350 (2004) 2383-2397
-
(2004)
N Engl J Med
, vol.350
, pp. 2383-2397
-
-
Pietrangelo, A.1
-
12
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle K.R., Frazer D.M., Wilkins S.J., Dixon J.L., Purdie D.M., Crawford D.H., et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 361 (2003) 669-673
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
Dixon, J.L.4
Purdie, D.M.5
Crawford, D.H.6
-
13
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E., Roetto A., Garozzo G., Ganz T., and Camaschella C. Hepcidin is decreased in TFR2 hemochromatosis. Blood 105 (2005) 1803-1806
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
Ganz, T.4
Camaschella, C.5
-
14
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G., Samuels M.E., Ludwig E.H., MacDonald M.L., Franchini P.L., Dube M.P., et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 36 (2004) 77-82
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
MacDonald, M.L.4
Franchini, P.L.5
Dube, M.P.6
-
15
-
-
0037564038
-
Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to serum transferrin saturation and non-transferrin-bound iron
-
Gehrke S.G., Kulaksiz H., Herrmann T., Riedel H.D., Bents K., Veltkamp C., et al. Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to serum transferrin saturation and non-transferrin-bound iron. Blood 102 (2003) 371-376
-
(2003)
Blood
, vol.102
, pp. 371-376
-
-
Gehrke, S.G.1
Kulaksiz, H.2
Herrmann, T.3
Riedel, H.D.4
Bents, K.5
Veltkamp, C.6
-
16
-
-
19544386871
-
Hepcidin in iron overload disorders
-
Papanikolaou G., Tzilianos M., Christakis J.I., Bogdanos D., Tsimirika K., MacFarlane J., et al. Hepcidin in iron overload disorders. Blood 105 (2005) 4103-4105
-
(2005)
Blood
, vol.105
, pp. 4103-4105
-
-
Papanikolaou, G.1
Tzilianos, M.2
Christakis, J.I.3
Bogdanos, D.4
Tsimirika, K.5
MacFarlane, J.6
-
17
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G., Bennoun M., Devaux I., Beaumont C., Grandchamp B., Kahn A., et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 98 (2001) 8780-8785
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
Beaumont, C.4
Grandchamp, B.5
Kahn, A.6
-
18
-
-
0038312385
-
Decreased liver hepcidin expression in the hfe knockout mouse
-
Ahmad K.A., Ahmann J.R., Migas M.C., Waheed A., Britton R.S., Bacon B.R., et al. Decreased liver hepcidin expression in the hfe knockout mouse. Blood Cells Mol Dis 29 (2002) 361-366
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 361-366
-
-
Ahmad, K.A.1
Ahmann, J.R.2
Migas, M.C.3
Waheed, A.4
Britton, R.S.5
Bacon, B.R.6
-
19
-
-
0037509928
-
Regulatory defects in liver and intestine implicate abnormal hepcidin and cybrd1 expression in mouse hemochromatosis
-
Muckenthaler M., Roy C.N., Custodio A.O., Minana B., DeGraaf J., Montross L.K., et al. Regulatory defects in liver and intestine implicate abnormal hepcidin and cybrd1 expression in mouse hemochromatosis. Nat Genet 34 (2003) 102-107
-
(2003)
Nat Genet
, vol.34
, pp. 102-107
-
-
Muckenthaler, M.1
Roy, C.N.2
Custodio, A.O.3
Minana, B.4
DeGraaf, J.5
Montross, L.K.6
-
20
-
-
19944427107
-
Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis
-
Kawabata H., Fleming R.E., Gui D., Moon S.Y., Saitoh T., O'Kelly J., et al. Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis. Blood 105 (2005) 376-381
-
(2005)
Blood
, vol.105
, pp. 376-381
-
-
Kawabata, H.1
Fleming, R.E.2
Gui, D.3
Moon, S.Y.4
Saitoh, T.5
O'Kelly, J.6
-
21
-
-
21044434748
-
First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin
-
Wallace D.F., Summerville L., Lusby P.E., and Subramaniam V.N. First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin. Gut 54 (2005) 980-986
-
(2005)
Gut
, vol.54
, pp. 980-986
-
-
Wallace, D.F.1
Summerville, L.2
Lusby, P.E.3
Subramaniam, V.N.4
-
22
-
-
23644460325
-
A mouse model of juvenile hemochromatosis
-
Huang F.W., Pinkus J.L., Pinkus G.S., Fleming M.D., and Andrews N.C. A mouse model of juvenile hemochromatosis. J Clin Invest 115 (2005) 2187-2191
-
(2005)
J Clin Invest
, vol.115
, pp. 2187-2191
-
-
Huang, F.W.1
Pinkus, J.L.2
Pinkus, G.S.3
Fleming, M.D.4
Andrews, N.C.5
-
23
-
-
23644444316
-
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
-
Niederkofler V., Salie R., and Arber S. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J Clin Invest 115 (2005) 2180-2186
-
(2005)
J Clin Invest
, vol.115
, pp. 2180-2186
-
-
Niederkofler, V.1
Salie, R.2
Arber, S.3
-
24
-
-
0346433908
-
Decreased hepcidin mRNA expression in thalassemic mice
-
Adamsky K., Weizer O., Amariglio N., Breda L., Harmelin A., Rivella S., et al. Decreased hepcidin mRNA expression in thalassemic mice. Br J Haematol 124 (2004) 123-124
-
(2004)
Br J Haematol
, vol.124
, pp. 123-124
-
-
Adamsky, K.1
Weizer, O.2
Amariglio, N.3
Breda, L.4
Harmelin, A.5
Rivella, S.6
-
25
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas G., Bennoun M., Porteu A., Mativet S., Beaumont C., Grandchamp B., et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA 99 (2002) 4596-4601
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Porteu, A.3
Mativet, S.4
Beaumont, C.5
Grandchamp, B.6
-
26
-
-
14644436419
-
Anemia of inflammation: the hepcidin link
-
Roy C.N., and Andrews N.C. Anemia of inflammation: the hepcidin link. Curr Opin Hematol 12 (2005) 107-111
-
(2005)
Curr Opin Hematol
, vol.12
, pp. 107-111
-
-
Roy, C.N.1
Andrews, N.C.2
-
27
-
-
14744278436
-
Anemia of chronic disease
-
Weiss G., and Goodnough L.T. Anemia of chronic disease. N Engl J Med 352 (2005) 1011-1023
-
(2005)
N Engl J Med
, vol.352
, pp. 1011-1023
-
-
Weiss, G.1
Goodnough, L.T.2
-
28
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
Donovan A., Lima C.A., Pinkus J.L., Pinkus G.S., Zon L.I., Robine S., et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab 1 (2005) 191-200
-
(2005)
Cell Metab
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
Pinkus, G.S.4
Zon, L.I.5
Robine, S.6
-
29
-
-
13444252281
-
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
-
Knutson M.D., Oukka M., Koss L.M., Aydemir F., and Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci USA 102 (2005) 1324-1328
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1324-1328
-
-
Knutson, M.D.1
Oukka, M.2
Koss, L.M.3
Aydemir, F.4
Wessling-Resnick, M.5
-
30
-
-
0024802647
-
Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers
-
Hallaway P.E., Eaton J.W., Panter S.S., and Hedlund B.E. Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers. Proc Natl Acad Sci USA 86 (1989) 10108-10112
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 10108-10112
-
-
Hallaway, P.E.1
Eaton, J.W.2
Panter, S.S.3
Hedlund, B.E.4
-
31
-
-
0035827697
-
2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts
-
2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. J Biol Chem 276 (2001) 19738-19745
-
(2001)
J Biol Chem
, vol.276
, pp. 19738-19745
-
-
Caltagirone, A.1
Weiss, G.2
Pantopoulos, K.3
-
32
-
-
27144467097
-
Altered body iron distribution and microcytosis in mice deficient for iron regulatory protein 2 (IRP2)
-
Galy B., Ferring D., Minana B., Bell O., Janser H.G., Muckenthaler M., et al. Altered body iron distribution and microcytosis in mice deficient for iron regulatory protein 2 (IRP2). Blood 106 (2005) 2580-2589
-
(2005)
Blood
, vol.106
, pp. 2580-2589
-
-
Galy, B.1
Ferring, D.2
Minana, B.3
Bell, O.4
Janser, H.G.5
Muckenthaler, M.6
-
33
-
-
0038662619
-
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
-
Nemeth E., Valore E.V., Territo M., Schiller G., Lichtenstein A., and Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 101 (2003) 2461-2463
-
(2003)
Blood
, vol.101
, pp. 2461-2463
-
-
Nemeth, E.1
Valore, E.V.2
Territo, M.3
Schiller, G.4
Lichtenstein, A.5
Ganz, T.6
-
34
-
-
1842608845
-
Iron metabolism and the IRE/IRP regulatory system: an update
-
Pantopoulos K. Iron metabolism and the IRE/IRP regulatory system: an update. Ann NY Acad Sci 1012 (2004) 1-13
-
(2004)
Ann NY Acad Sci
, vol.1012
, pp. 1-13
-
-
Pantopoulos, K.1
-
35
-
-
28444488323
-
-
Delaby C, Pilard N, Goncalves AS, Beaumont C, Canonne-Hergaux F. The presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and downregulated by hepcidin. Blood 2005; 106:3979-3984.
-
-
-
-
36
-
-
0030608152
-
The ferritins: molecular properties, iron storage function and cellular regulation
-
Harrison P.M., and Arosio P. The ferritins: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta 1275 (1996) 161-203
-
(1996)
Biochim Biophys Acta
, vol.1275
, pp. 161-203
-
-
Harrison, P.M.1
Arosio, P.2
|