Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production

Journal of Neuroimmunology

Volumn 174, Issue 1-2, 2006, Pages 39-51

  Candelario Jalil, Eduardo ^a   Akundi, Ravi S ^a   Bhatia, Harsharan S ^a   Lieb, Klaus ^a   Appel, Kurt ^b   Muñoz, Eduardo ^c   Hüll, Michael ^a   Fiebich, Bernd L ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b VIVACELL BIOTECHNOLOGY GMBH   (Germany)

^c UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

8 Isoprostanes; Alzheimer's disease; Cyclooxygenase 2; Neuroinflammation; NSAIDs; Oxidative stress; Prostaglandin E synthase; Reactive oxygen species; Stroke; Vitamin C

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; 8 ISOPROSTAGLANDIN F2 ALPHA; ACETYLSALICYLIC ACID; ASCORBIC ACID; CYCLOOXYGENASE 2; INDOMETACIN; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MARKER; DRUG INHIBITION; DRUG POTENCY; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NERVE CELL CULTURE; NEUROPROTECTION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROSTAGLANDIN SYNTHESIS INHIBITION;

ANTIOXIDANTS; ASCORBIC ACID; ASPIRIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DINOPROST; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GENE EXPRESSION; HUMANS; INTERLEUKIN-1; NEURAL INHIBITION; NEUROBLASTOMA; NEURONS;

EID: 33646114296     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2006.01.003     Document Type: Article

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