In silico modelling of the interaction of flavonoids with human P-glycoprotein nucleotide-binding domain

European Journal of Medicinal Chemistry

Volumn 41, Issue 3, 2006, Pages 285-295

  Badhan, Raj ^a   Penny, Jeffrey ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

ABCB1; Flavonoid; Homology modelling; Nucleotide binding domain

Indexed keywords

ABC TRANSPORTER; AMINO ACID; BENZYL DERIVATIVE; CARBONYL DERIVATIVE; DOCKING PROTEIN; FLAVONOID; GLYCOPROTEIN P; HYDROCARBON; HYDROXYL GROUP; LYSINE; MULTIDRUG RESISTANCE PROTEIN 1; NUCLEOTIDE BINDING PROTEIN; PRENYLAMINE; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TYROSINE; UNCLASSIFIED DRUG; DNA BINDING PROTEIN;

ARTICLE; BINDING AFFINITY; COMPUTER MODEL; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STATISTICAL MODEL; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; DNA-BINDING PROTEINS; FLAVONOIDS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; P-GLYCOPROTEIN; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT;

EID: 33645972931     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.11.012     Document Type: Article

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