Mechanism of acetaminophen-induced hepatotoxicity: Covalent binding versus oxidative stress

Chemical Research in Toxicology

Volumn 9, Issue 3, 1996, Pages 580-585

  Gibson, Jennifer D ^a   Pumford, Neil R ^a   Samokyszyn, Victor M ^a   Hinson, Jack A ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALDEHYDE; BOVINE SERUM ALBUMIN; FERROUS SULFATE; PARACETAMOL; TERT BUTYL HYDROPEROXIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COVALENT BOND; IMMUNOBLOTTING; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANALGESICS, NON-NARCOTIC; ANIMALS; BLOTTING, WESTERN; GLUTATHIONE; LIVER; MALE; MICE; OXIDATIVE STRESS; PROTEIN BINDING; REACTIVE OXYGEN SPECIES;

ANIMALIA; BOVINAE;

EID: 0029961590     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950153d     Document Type: Article

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