Regular exercise: An effective means to reduce oxidative stress in old rats

Annals of the New York Academy of Sciences

Volumn 1019, Issue , 2004, Pages 471-474

  Goto, Sataro ^a   Radák, Zsolt ^b   Nyakas, Csaba ^b   Hae, Young Chung ^c   Naito, Hisashi ^d   Takahashi, Ryoya ^a   Nakamoto, Hideko ^a   Abe, Ryoichi ^a  

^a TOHO UNIVERSITY   (Japan)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c Pusan National University   (South Korea)

^d JUNTENDO UNIVERSITY   (Japan)

Author keywords

Damage; Exercise; NF B; Old; Oxidative; Rats; Stress

Indexed keywords

ANTIOXIDANT; BETA 2 ADRENERGIC RECEPTOR; BRAIN PROTEIN; CARBONYL DERIVATIVE; CYCLOOXYGENASE 2; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUTATHIONE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOCORTIN 1; N TERT BUTYL ALPHA PHENYLNITRONE; PROTEIN P50; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

AGING; ASTHMA; BODY WEIGHT; COGNITION; CONFERENCE PAPER; CYTOKINE PRODUCTION; ENZYME ACTIVITY; EXERCISE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HEART MUSCLE OXYGEN CONSUMPTION; HEPATITIS; HORMONE BLOOD LEVEL; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SWIMMING; TRANSCRIPTION INITIATION; TREADMILL; UPREGULATION; WESTERN BLOTTING;

EID: 3242723070     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1297.085     Document Type: Conference Paper

References (11)

1. REZNICK, A.Z., E. WITT, M. MATSUMOTO & L. PACKER. 1992. Vitamin E inhibits protein oxidation in skeletal muscle of resting and exercised rats. Biochem. Biophys. Res. Commun. 189: 801-806.
2. RADÁK, Z., A. NAKAMURA, H. NAKAMOTO, et al. 1998. A period of anaerobic exercise increases the accumulation of reactive carbonyl derivatives in the lungs of rats. Pflüg. Arch. 435: 439-441.
3. RADÁK, Z., T. KANEKO, S. TAHARA, et al. 2001. Regular exercise improves cognitive function and decreases oxidative damage in rat brain. Neurochem. Int. 38: 17-23.
4. CARNEY, J.M., P.E. STARKE-REED, C.N. OLIVER, et al. 1991. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone. Proc. Natl. Acad. Sci. USA 88: 3633-3636.
5. POWERS, S.K., D. CRISWELL, J. LAWLER, et al. 1994. Influence of exercise and fiber type on antioxidant enzyme activity in rat skeletal muscle. Am. J. Physiol. 266: R375-R380.
6. RADÁK, Z., T. KANEKO, S. TAHARA, et al. 1999. The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes. Free Radical Biol. Med. 27: 69-74.
7. RADÁK, Z., H. NAITO, T. KANEKO, et al. 2002. Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflüg. Arch. 445: 273-278.
8. RADÁK, Z., H.Y. CHUNG, H. NAITO, et al. 2004. Age-associated increase in oxidative stress and nuclear factor kappaB activation are attenuated in rat liver by regular exercise. FASAB J. 18: 749-750.
9. CHUNG, H.Y., H.J. KIM, J.W. KIM & B.P. YU. 2001. The inflammation hypothesis of aging: molecular modulation by calorie restriction. Ann. N.Y. Acad. Sci. 928: 327-335.
10. ADCOCK, I.M. 2000. Molecular mechanisms of glucocorticosteroid actions. Pulm. Pharmacol. Ther. 13: 115-126.
11. RAY, A. & K.E. PREFONTAINE. 1994. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 91: 752-756.