Advances in the vascular pathophysiology of ischemic stroke

Thrombosis Research

Volumn 98, Issue 3, 2000, Pages 73-81

  Del Zoppo, Gregory J ^a   Hallenbeck, John M ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Astrocyte; Cerebral ischemia; Endothelial cell; Inflammation; Microvessel; Stroke

Indexed keywords

CYTOKINE; INTEGRIN; MATRIX METALLOPROTEINASE; VASCULOTROPIN;

ARTICLE; ASTROCYTE; AUTOREGULATION; BLOOD BRAIN BARRIER; BLOOD VESSEL REACTIVITY; BRAIN BLOOD FLOW; BRAIN CAPILLARY; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; BRAIN MICROCIRCULATION; CELL INTERACTION; CELL MEMBRANE PERMEABILITY; CEREBROVASCULAR ACCIDENT; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; HUMAN; LEUKOCYTE ADHERENCE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECANALIZATION;

EID: 0034192486     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0049-3848(00)00218-8     Document Type: Article

References (67)

1. Zülch K.-J. The Cerebral Infarct. Pathology, Pathogenesis, and Computed Tomography:1985;Springer-Verlag, Heidelberg. p. 23-9.
2. Bär T., Wolff J.R. The formation of capillary basement membranes during internal vascularization of the rat's cerebral cortex. Z Zellforsch. 133:1972;231-248.
3. Bär T. The vascular system of the cerebral cortex. Adv Anat Embryol Cell Biol. 59(I-VI):1980;1-62.
4. Fenstermacher J., Nakata H., Tajima A., Lin S.Z., Otsuka T., Acuff V., Wei L., Bereczki D. Functional variations in parenchymal microvascular systems within the brain. Magn Reson Med. 19:1991;217-220.
5. rd ed:1991;Oxford University Press, New York. p. 352-3.
6. Bernstein J.J., Getz R., Jefferson M., Kelemen M. Astrocytes secrete basal lamina after hemisection of rat spinal cord. Brain Res. 327:1985;135-141.
7. Kusaka H., Hirano A., Bornstein M.B., Raine C.S. Basal lamina formation by astrocytes in organotypic cultures of mouse spinal cord tissue. J Neuropathol Exp Neurol. 44:1985;295-303.
8. Nagano N., Aoyagi M., Hirakawa K. Extracellular matrix modulates the proliferation of rat astrocytes in serum-free culture. Glia. 8:1993;71-76.
9. Janzer R.C., Raff M.C. Astrocytes induce blood-brain barrier properties in endothelial cells (letter). Nature. 325:1987;353-355.
10. Tagami M., Yamagata K., Fujino H., Kubota A., Nara Y., Yamori Y. Morphological differentiation of endothelial cells co-cultured with astrocytes on type-I or type-IV collagen. Cell Tissue Res. 268:1992;225-232.
11. Webersinke G., Bauer H., Amberger A., Zach O., Bauer H.C. Comparison of gene expression of extracellular matrix molecules in brain microvascular endothelial cells and astrocytes. Biochem Biophys Res Commun. 189:1992;877-884.
12. Hallenbeck J.M., Kochanek P.M. Inflammatory responses in cerebral ischemia. role of leukocytes Ginsberg M.D., Bogousslavsky J. Cerebrovascular Disease. Pathophysiology, Diagnosis and Management:1998;489-506 Blackwell Science, Inc, Malden, MA.
13. Hallenbeck J.M., Dutka A.J., Kochanek P.M., Siren A., Pezeshkpour G.H., Feuerstein G.Z. Stroke risk factors prepare rat brainstem tissues for modified local Schwartzman reaction. Stroke. 19:1988;863-869.
14. Risau W., Wolburg H. Development of the blood-brain barrier. TINS. 13:1990;174-178.
15. Okada Y., Copeland B.R., Fitridge R., Koziol J.A., del Zoppo G.J. Fibrin contributes to microvascular obstructions and parenchymal changes during early focal cerebral ischemia and reperfusion. Stroke. 25:1994;1847-1854.
16. 4 during focal cerebral ischemia/reperfusion. Stroke. 28:1997;858-865.
17. Hamann C.F., Okada Y., Fitridge R., del Zoppo G.J. Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. Stroke. 26:1995;2120-2126.
18. Hamann G.F., Okada Y., del Zoppo G.J. Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion. J Cereb Blood Flow Metab. 16:1996;1373-1378.
19. Takahashi S., Cook M., Jehle J., Kennedy C., Sokoloff L. Preservation of autoregulatory cerebral vasodilator responses to hypotension after inhibition of nitric oxide synthesis. Brain Res. 678:1995;21-28.
20. Faraci F. Regulation of the cerebral circulation by endothelium. Pharmacol Ther. 56:1992;1-22.
21. Macrae I.M., Robinson M.J., Graham D.I., Reid J.L., McCulloch J. Endothelin-1-induced reductions in cerebral blood flow. Dose dependency, time course and neuropathological consequences J Cereb Blood Flow Metab. 13:1993;276-284.
22. Nag S., Robertson D.M. Gross pathologic anatomic. Wood J.H. Cerebral Blood Flow. 1987;59-74 McGraw-Hill, New York.
23. del Zoppo G.J., Poeck K., Pessin M.S., Wolpert S.M., Furlan A.J., Ferbert A., Alberts M.J., Zivin J.A., Wechsler L., Busse O.et al. Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann Neurol. 32:1992;78-86.
24. del Zoppo G.J., Higashida R.T., Furlan A.J., Pessin M.S., Rowley H.A., Gent M. Proact. A phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke Stroke. 29:1998;4-11.
25. Fieschi C., Argentino C., Lenzi G.L., Sacchetti M.L., Toni D., Bozzao L. Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours. J Neurol Sci. 91:1989;311-321.
26. Solis O.J., Roberson G.R., Taveras J.M., Mohr J., Pessin M.S. Cerebral angiography in acute cerebral infarction. Revist Interam Radiol. 2:1977;19-25.
27. Fieschi C., Bozzao L. Transient embolic occlusion of the middle cerebral and internal carotid arteries in cerebral apoplexy. J Neurol Neurosurg Psychiatry. 32:1969;236-240.
28. Irino T., Taneda M., Minami T. Angiographic manifestations in post-recanalized cerebral infarction. Neurology. 27:1977;471-475.
29. Mori E., Yoneda Y., Tabuchi M., Yoshida T., Ohkawa S., Ohsumi Y., Kitano K., Tsutsumi A., Yamadori A. Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke. Neurology. 42:1992;976-982.
30. Yamaguchi T. Intravenous tissue plasminogen activator in acute thromboembolic stroke. a placebo-controlled, double-blind trial del Zoppo G.J., Mori E., Hacke W. Thrombolytic Therapy in Acute Ischemic Stroke II. 1993;59-65 Springer-Verlag, Heidelberg.
31. Fisher C.M., Adams R.D. Observations on brain embolism with special reference to the mechanism of hemorrhagic infarction. J Neuropathol Exp Neurol. 10:1951;92-94.
32. Okada Y., Yamaguchi T., Minematsu K., Miyashita T., Sawada T., Sadoshima S., Fujishima M., Omae T. Hemorrhagic transformation in cerebral embolism. Stroke. 20:1989;598-603.
33. Hornig C.R., Dorndorf W., Agnoli A.L. Hemorrhagic cerebral infarction. a prospective study Stroke. 17:1986;179-185.
34. Meyer JS, Gilroy J, Barnhart ME, Johnson JF. Therapeutic thrombolysis in cerebral thromboembolism: randomized evaluation of intravenous streptokinase. In: Millikan CH, Siekert RG, Whisnant JP, editors. Cerebral Vascular Diseases, Fourth Princeton Conference. New York: Grune and Stratton; 1965. p. 200-13.
35. Babikian V.L., Kase C.S., Pessin M.S., Norrving B., Gorelick P.B. Intracerebral hemorrhage in stroke patients anticoagulated with heparin. Stroke. 29:1989;1500-1503.
36. Koller R.L. Recurrent embolic cerebral infarction and anticoagulation. Neurology. 32:1982;283-285.
37. del Zoppo G.J., Ferbert A., Otis S., Bruckmann H., Hacke W., Zyroff J., Harker L.A., Zeumer H. Local intra-arterial fibrinolytic therapy in acute carotid territory stroke. A pilot study. Stroke. 19:1988;307-313.
38. Mori E., Tabuchi M., Yoshida T., Yamadori A. Intracarotid urokinase with thromboembolic occlusion of the middle cerebral artery. Stroke. 19:1988;802-812.
39. Ogata J., Yutani C., Imakita M., Ishibashi-Ueda H., Saku Y., Minematsu K., Sawada T., Yamaguchi T. Hemorrhagic infarct of the brain without a reopening of the occluded arteries in cardioembolic stroke. Stroke. 20:1989;876-883.
40. Rosenberg G.A., Dencoff J.E., McGuire P.G., Liotta L.A., Stetler-Stevenson W.G. Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain. Lab Invest. 71:1994;417-422.
41. Heo J., Lucero J., Abumiya T., Koziol J., Copeland B., del Zoppo G. Matrix metalloproteinases increase very early during experimental focal ischemia. J Cereb Blood Flow Metab. 19:1999;624-633.
42. Gaetani P., Rodriguez y Baena R., Tartara F., Messina A.L., Tancioni F., Schiavo R., Grazioli V. Metalloproteases and intracranial vascular lesions. Neurol Res. 21(4):1999;385-390.
43. Carmeliet P., Moons L., Lijnen R., Baes M., Lemaitre V., Tipping P., Drew A., Eeckhout Y., Shapiro S., Lupu F., Collen D. Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation. Nature Genetics. 17(4):1997;439-444.
44. Tamarina N.A., McMillan W.D., Shively V.P., Pearce W.H. Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta. Surgery. 122(2):1997;264-271.
45. Risau W., Hallmann R., Albrecht U., Henke-Fahle S. Brain astrocytes induce the expression of an early cell surface marker for blood-brain barrier specific endothelium. EMBO J. 5:1986;3179-3183.
46. Thomas W.S., Mori E., Copeland B.R., Yu J.-Q., Morrissey J.H., del Zoppo G.J. Tissue factor contributes to microvascular defects following cerebral ischemia. Stroke. 24:1993;847-853.
47. Okada Y., Copeland B.R., Mori E., Tung M.-M., Thomas W.S., del Zoppo G.J. P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion. Stroke. 25:1994;202-211.
48. Haring H.-P., Berg E.L., Tsurushita N., Tagaya M., del Zoppo G.J. E-selectin appears in non-ischemic tissue during experimental focal cerebral ischemia. Stroke. 27:1996;1386-1392.
49. Garcia J.H., Liu K.F., Yoshida Y., Lian J., Chen S., del Zoppo G.J. Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). Am J Pathol. 144:1994;188-199.
50. Sirén A.L., Heldman E., Doron D., Lysko P.G., Yue T.L., Liu Y., Feuerstein G., Hallenbeck J.M. Release of proinflammatory and prothrombotic mediators in the brain and peripheral circulation in spontaneously hypertensive and normotensive Wistar-Kyoto rats. Stroke. 23:1992;1643-1651.
51. Dawson D.A., Furuya K., Gotoh J., Yasuaki N., Hallenbeck J.M. Cerebral hemodynamics and ischemic tolerance. lipopolysaccharide-induced resistance to focal cerebral ischemia is not due to changes in severity of the initial ischemic insult, but is associated with preservation of microvascular perfusion J Cereb Blood Flow Metab. 19:1999;616-623.
52. Symon L. Pathological regulation in cerebral ischemia. Wood J.A. Cerebral Blood Flow. 1987;413-424 McGraw-Hill Book Company, New York.
53. Lenzi G.L., Frackowiak R.S.J., Jones T. Cerebral oxygen metabolism and blood flow in human cerebral ischemic infarction. J Cereb Blood Flow Metab. 2:1982;321-335.
54. Weiss H.R., Buchweitz E.L., Murtha T.J., Auletta M. Quantitative regional determinatin of morphometric indices of the total and perfused capillary network in the rat brain. Circ Res. 51:1982;494-503.
55. Symon L. Regional vascular reactivity in the middle cerebral arterial distribution. an experimental study in baboons J Neurosurg. 33:1970;532-541.
56. Moncada S., Radomski M.W., Palmer R.M.J. Endothelium-derived relaxing factor. identification as nitric oxide and role in the control of vascular tone and platelet function Biochem Pharmacol. 37:1988;2495-2501.
57. Huang Z., Huang P.L., Ma J., Meng W., Ayata C., Fishman M.C., Moskowitz M.A. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb Blood Flow Metab. 16:1996;981-987.
58. Huang Z., Huang P.L., Panahian N., Dalkara T., Fishman M.C., Moskowitz M.A. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 265:1994;1883-1885.
59. Tagaya M., Liu K.F., Copeland B., Seiffert D., Engler R., Garcia J.H., del Zoppo G.J. DNA scission following focal brain ischemia. temporal differences in two species Stroke. 28:1997;1245-1254.
60. 3 during focal cerebral ischemia. J Cereb Blood Flow Metab. 19:1999;1038-1050.
61. 3 is expressed in selected microvessels following focal cerebral ischemia. Am J Pathol. 149:1996;37-44.
62. del Zoppo G.J., Schmid-Schönbein G.W., Mori E., Copeland B.R., Chang C.-M. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke. 22:1991;1276-1283.
63. Garcia J.H., Kamijyo Y. Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates. J Neuropathol Exp Neurol. 33:1974;408-421.
64. st ed:1987;75-91 McGraw-Hill, New York.
65. Garcia J.H., Liu K.-F., Lian J., Xu J. Astrocytic and microvascular responses to the occlusion of a middle cerebral artery (Wistar rat). J Neuropathol Exp Neurol. 52:1993;288.
66. del Zoppo G.J., Copeland B.R., Harker L.A., Waltz T.A., Zyroff J., Hanson S.R., Battenberg E. Experimental acute thrombotic stroke in baboons. Stroke. 17:1986;1254-1265.
67. st. 1983;169-182 Raven Press, New York.