-
1
-
-
0031861905
-
Long-lived plasma cells: A mechanism for maintaining persistent antibody production
-
Slifka MK Ahmed R. Long-lived plasma cells: a mechanism for maintaining persistent antibody production. Curr Opin Immunol 1998 10 252 258.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 252-258
-
-
Slifka, M.K.1
Ahmed, R.2
-
2
-
-
0037818485
-
Gene expression profiling of plasma cells and plasmablasts: Toward a better understanding of the late stages of B-cell differentiation
-
Tarte K Zhan F De Vos J Klein B Shaughnessy J Jr.. Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation. Blood 2003 102 592 600.
-
(2003)
Blood
, vol.102
, pp. 592-600
-
-
Tarte, K.1
Zhan, F.2
De Vos, J.3
Klein, B.4
Shaughnessy Jr., J.5
-
3
-
-
0034573189
-
BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells
-
Piskurich JF Lin KI Lin Y Wang Y Ting JP Calame K. BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nat Immunol 2000 1 526 532.
-
(2000)
Nat Immunol
, vol.1
, pp. 526-532
-
-
Piskurich, J.F.1
Lin, K.I.2
Lin, Y.3
Wang, Y.4
Ting, J.P.5
Calame, K.6
-
5
-
-
18444395232
-
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
-
Shaffer AL et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 2002 17 51 62.
-
(2002)
Immunity
, vol.17
, pp. 51-62
-
-
Shaffer, A.L.1
-
6
-
-
0030950523
-
Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation
-
Lin Y Wong K Calame K. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science 1997 276 596 599.
-
(1997)
Science
, vol.276
, pp. 596-599
-
-
Lin, Y.1
Wong, K.2
Calame, K.3
-
7
-
-
0033680860
-
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
-
Shaffer AL Yu X He Y Boldrick J Chan EP Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 2000 13 199 212.
-
(2000)
Immunity
, vol.13
, pp. 199-212
-
-
Shaffer, A.L.1
Yu, X.2
He, Y.3
Boldrick, J.4
Chan, E.P.5
Staudt, L.M.6
-
8
-
-
10344247666
-
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
-
Phan RT Dalla-Favera R. The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 2004 432 635 639.
-
(2004)
Nature
, vol.432
, pp. 635-639
-
-
Phan, R.T.1
Dalla-Favera, R.2
-
9
-
-
5344280456
-
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation
-
Fujita N et al. MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell 2004 119 75 86.
-
(2004)
Cell
, vol.119
, pp. 75-86
-
-
Fujita, N.1
-
10
-
-
0036272784
-
Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells
-
Lin KI Angelin-Duclos C Kuo TC Calame K. Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol Cell Biol 2002 22 4771 4780.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4771-4780
-
-
Lin, K.I.1
Angelin-Duclos, C.2
Kuo, T.C.3
Calame, K.4
-
11
-
-
0032189224
-
Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer
-
Muto A et al. Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer. EMBO J 1998 17 5734 5743.
-
(1998)
EMBO J
, vol.17
, pp. 5734-5743
-
-
Muto, A.1
-
12
-
-
0029045161
-
Failure of B-cell differentiation in mice lacking the transcription factor EBF
-
Lin H Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 1995 376 263 267.
-
(1995)
Nature
, vol.376
, pp. 263-267
-
-
Lin, H.1
Grosschedl, R.2
-
13
-
-
15444346834
-
Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
-
Mittrucker HW et al. Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 1997 275 540 543.
-
(1997)
Science
, vol.275
, pp. 540-543
-
-
Mittrucker, H.W.1
-
14
-
-
18644372880
-
Differential requirement for OBF-1 during antibody-secreting cell differentiation
-
Corcoran LM et al. Differential requirement for OBF-1 during antibody-secreting cell differentiation. J Exp Med 2005 201 1385 1396.
-
(2005)
J Exp Med
, vol.201
, pp. 1385-1396
-
-
Corcoran, L.M.1
-
15
-
-
0037167847
-
Dec1 and Dec2 are regulators of the mammalian molecular clock
-
Honma S et al. Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature 2002 419 841 844.
-
(2002)
Nature
, vol.419
, pp. 841-844
-
-
Honma, S.1
-
16
-
-
0037103205
-
Generation of polyclonal plasmablasts from peripheral blood B cells: A normal counterpart of malignant plasmablasts
-
Tarte K et al. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood 2002 100 1113 1122.
-
(2002)
Blood
, vol.100
, pp. 1113-1122
-
-
Tarte, K.1
-
17
-
-
1542360757
-
Normal and malignant human plasma cells: Proliferation, differentiation, and expansions in relation to CD45 expression
-
Pellat-Deceunynck C Bataille R. Normal and malignant human plasma cells: proliferation, differentiation, and expansions in relation to CD45 expression. Blood Cells Mol Dis 2004 32 293 301.
-
(2004)
Blood Cells Mol Dis
, vol.32
, pp. 293-301
-
-
Pellat-Deceunynck, C.1
Bataille, R.2
-
18
-
-
20444400843
-
Phenotypic characterization of the human myeloma cell growth fraction
-
Robillard N Pellat-Deceunynck C Bataille R. Phenotypic characterization of the human myeloma cell growth fraction. Blood 2005 105 4845 4848.
-
(2005)
Blood
, vol.105
, pp. 4845-4848
-
-
Robillard, N.1
Pellat-Deceunynck, C.2
Bataille, R.3
-
20
-
-
0032533909
-
Induction of CD45 expression and proliferation in U-266 myeloma cell line by interleukin-6
-
Mahmoud MS Ishikawa H Fujii R Kawano MM. Induction of CD45 expression and proliferation in U-266 myeloma cell line by interleukin-6. Blood 1998 92 3887 3897.
-
(1998)
Blood
, vol.92
, pp. 3887-3897
-
-
Mahmoud, M.S.1
Ishikawa, H.2
Fujii, R.3
Kawano, M.M.4
-
21
-
-
0034161432
-
Purification of human tonsil plasma cells. pre-enrichment step by immunomagnetic selection of CD31 (+) cells
-
Medina F Segundo C Brieva JA. Purification of human tonsil plasma cells. pre-enrichment step by immunomagnetic selection of CD31 (+) cells. Cytometry 2000 39 231 234.
-
(2000)
Cytometry
, vol.39
, pp. 231-234
-
-
Medina, F.1
Segundo, C.2
Brieva, J.A.3
-
22
-
-
79960971480
-
Molecular profiling newly diagnosed multiple myeloma
-
Zhan F et al. Molecular profiling newly diagnosed multiple myeloma. Blood 2001 98 733a.
-
(2001)
Blood
, vol.98
-
-
Zhan, F.1
-
23
-
-
13544251387
-
Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response
-
Odendahl M et al. Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood 2005 105 1614 1621.
-
(2005)
Blood
, vol.105
, pp. 1614-1621
-
-
Odendahl, M.1
-
25
-
-
0033119201
-
The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
-
Ma Q Jones D Springer TA. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 1999 10 463 471.
-
(1999)
Immunity
, vol.10
, pp. 463-471
-
-
Ma, Q.1
Jones, D.2
Springer, T.A.3
-
26
-
-
0035796411
-
A coordinated change in chemokine responsiveness guides plasma cell movements
-
Hargreaves DC et al. A coordinated change in chemokine responsiveness guides plasma cell movements. J Exp Med 2001 194 45 56.
-
(2001)
J Exp Med
, vol.194
, pp. 45-56
-
-
Hargreaves, D.C.1
-
27
-
-
0032797272
-
Chemokines and cell migration in secondary lymphoid organs
-
Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science 1999 286 2098 2102.
-
(1999)
Science
, vol.286
, pp. 2098-2102
-
-
Cyster, J.G.1
-
28
-
-
0035437195
-
Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays
-
De Vos J et al. Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays. Blood 2001 98 771 780.
-
(2001)
Blood
, vol.98
, pp. 771-780
-
-
De Vos, J.1
-
30
-
-
0028328436
-
Impaired immune and acute-phase responses in interleukin-6-deficient mice
-
Kopf M et al. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 1994 368 339 342.
-
(1994)
Nature
, vol.368
, pp. 339-342
-
-
Kopf, M.1
-
31
-
-
0345317621
-
IgG1 plasmacytosis in interleukin 6 transgenic mice
-
Suematsu S et al. IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc Natl Acad Sci USA 1989 86 7547 7551.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7547-7551
-
-
Suematsu, S.1
-
32
-
-
0035869281
-
Interleukin-6 is a growth factor for nonmalignant human plasmablasts
-
Jego G Bataille R Pellat-Deceunynck C. Interleukin-6 is a growth factor for nonmalignant human plasmablasts. Blood 2001 97 1817 1822.
-
(2001)
Blood
, vol.97
, pp. 1817-1822
-
-
Jego, G.1
Bataille, R.2
Pellat-Deceunynck, C.3
-
33
-
-
0141765902
-
New insights into the pathophysiology of multiple myeloma
-
Seidl S Kaufmann H Drach J. New insights into the pathophysiology of multiple myeloma. Lancet Oncol 2003 4 557 564.
-
(2003)
Lancet Oncol
, vol.4
, pp. 557-564
-
-
Seidl, S.1
Kaufmann, H.2
Drach, J.3
-
34
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan CY Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004 20 781 810.
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
35
-
-
0035383761
-
Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand
-
Han JH Choi SJ Kurihara N Koide M Oba Y Roodman GD. Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand. Blood 2001 97 3349 3353.
-
(2001)
Blood
, vol.97
, pp. 3349-3353
-
-
Han, J.H.1
Choi, S.J.2
Kurihara, N.3
Koide, M.4
Oba, Y.5
Roodman, G.D.6
-
36
-
-
0037105582
-
A molecular compendium of genes expressed in multiple myeloma
-
Claudio JO et al. A molecular compendium of genes expressed in multiple myeloma. Blood 2002 100 2175 2186.
-
(2002)
Blood
, vol.100
, pp. 2175-2186
-
-
Claudio, J.O.1
-
37
-
-
23044443492
-
Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
-
Salzer U et al. Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nat Genet 2005 37 820 828.
-
(2005)
Nat Genet
, vol.37
, pp. 820-828
-
-
Salzer, U.1
-
39
-
-
0347285357
-
BCMA is essential for the survival of long-lived bone marrow plasma cells
-
O'Connor BP et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 2004 199 91 98.
-
(2004)
J Exp Med
, vol.199
, pp. 91-98
-
-
O'Connor, B.P.1
-
40
-
-
16844364286
-
The BAFF/APRIL system: Life beyond B lymphocytes
-
Ng LG Mackay CR Mackay F. The BAFF/APRIL system: life beyond B lymphocytes. Mol Immunol 2005 42 763 772.
-
(2005)
Mol Immunol
, vol.42
, pp. 763-772
-
-
Ng, L.G.1
MacKay, C.R.2
MacKay, F.3
-
41
-
-
23044512143
-
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
-
Moreaux J et al. The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature. Blood 2005 106 1021 1030.
-
(2005)
Blood
, vol.106
, pp. 1021-1030
-
-
Moreaux, J.1
-
42
-
-
20844432040
-
Identification of proteoglycans as the APRIL-specific binding partners
-
Ingold K et al. Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med 2005 201 1375 1383.
-
(2005)
J Exp Med
, vol.201
, pp. 1375-1383
-
-
Ingold, K.1
-
43
-
-
0033450858
-
The Mi15 monoclonal antibody (anti-syndecan-1) is a reliable marker for quantifying plasma cells in paraffin-embedded bone marrow biopsy specimens
-
Costes V et al. The Mi15 monoclonal antibody (anti-syndecan-1) is a reliable marker for quantifying plasma cells in paraffin-embedded bone marrow biopsy specimens. Hum Pathol 1999 30 1405 1411.
-
(1999)
Hum Pathol
, vol.30
, pp. 1405-1411
-
-
Costes, V.1
-
44
-
-
0035063860
-
Proximal promoter of the murine syndecan-1 gene is not sufficient for the developmental pattern of syndecan expression in B lineage cells
-
Volpe CP et al. Proximal promoter of the murine syndecan-1 gene is not sufficient for the developmental pattern of syndecan expression in B lineage cells. Am J Hematol 2001 67 20 26.
-
(2001)
Am J Hematol
, vol.67
, pp. 20-26
-
-
Volpe, C.P.1
-
45
-
-
0030742381
-
Large scale and clinical grade purification of syndecan-1+ malignant plasma cells
-
Sun RX et al. Large scale and clinical grade purification of syndecan-1+ malignant plasma cells. J Immunol Methods 1997 205 73 79.
-
(1997)
J Immunol Methods
, vol.205
, pp. 73-79
-
-
Sun, R.X.1
-
46
-
-
0032851160
-
Functions of cell surface heparan sulfate proteoglycans
-
Bernfield M et al. Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem 1999 68 729 777.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 729-777
-
-
Bernfield, M.1
-
47
-
-
0034307372
-
Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins
-
Borset M Hjertner O Yaccoby S Epstein J Sanderson RD. Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins. Blood 2000 96 2528 2536.
-
(2000)
Blood
, vol.96
, pp. 2528-2536
-
-
Borset, M.1
Hjertner, O.2
Yaccoby, S.3
Epstein, J.4
Sanderson, R.D.5
-
48
-
-
0033594411
-
Tyro-3 family receptors are essential regulators of mammalian spermatogenesis
-
Lu Q et al. Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature 1999 398 723 728.
-
(1999)
Nature
, vol.398
, pp. 723-728
-
-
Lu, Q.1
-
49
-
-
0035831454
-
Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts
-
Katagiri M et al. Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts. J Biol Chem 2001 276 7376 7382.
-
(2001)
J Biol Chem
, vol.276
, pp. 7376-7382
-
-
Katagiri, M.1
-
50
-
-
0035854442
-
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
-
Lu Q Lemke G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 2001 293 306 311.
-
(2001)
Science
, vol.293
, pp. 306-311
-
-
Lu, Q.1
Lemke, G.2
-
51
-
-
0035126319
-
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis
-
Angelillo-Scherrer A et al. Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis. Nat Med 2001 7 215 221.
-
(2001)
Nat Med
, vol.7
, pp. 215-221
-
-
Angelillo-Scherrer, A.1
-
52
-
-
0034650987
-
Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway
-
Lan Z et al. Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway. Blood 2000 95 633 638.
-
(2000)
Blood
, vol.95
, pp. 633-638
-
-
Lan, Z.1
-
53
-
-
1642535589
-
Expression of the receptor tyrosine kinase Axl promotes ocular melanoma cell survival
-
van Ginkel PR et al. Expression of the receptor tyrosine kinase Axl promotes ocular melanoma cell survival. Cancer Res 2004 64 128 134.
-
(2004)
Cancer Res
, vol.64
, pp. 128-134
-
-
Van Ginkel, P.R.1
-
54
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H Matsui T Yamamoto A Okada T Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001 107 881 891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
55
-
-
0035913294
-
Plasma cell differentiation requires the transcription factor XBP-1
-
Reimold AM et al. Plasma cell differentiation requires the transcription factor XBP-1. Nature 2001 412 300 307.
-
(2001)
Nature
, vol.412
, pp. 300-307
-
-
Reimold, A.M.1
-
57
-
-
3142658576
-
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
Shaffer AL et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004 21 81 93.
-
(2004)
Immunity
, vol.21
, pp. 81-93
-
-
Shaffer, A.L.1
-
58
-
-
0142059951
-
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
-
Lee AH Iwakoshi NN Glimcher LH. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 2003 23 7448 7459.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7448-7459
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Glimcher, L.H.3
-
59
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak SJ et al. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 2004 18 3066 3077.
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
-
60
-
-
0026786675
-
Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation
-
Bakkus MH Heirman C Van Riet I Van Camp B Thielemans K. Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation. Blood 1992 80 2326 2335.
-
(1992)
Blood
, vol.80
, pp. 2326-2335
-
-
Bakkus, M.H.1
Heirman, C.2
Van Riet, I.3
Van Camp, B.4
Thielemans, K.5
-
62
-
-
0032748385
-
Antitumor activity of thalidomide in refractory multiple myeloma
-
Singhal S et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999 341 1565 1571.
-
(1999)
N Engl J Med
, vol.341
, pp. 1565-1571
-
-
Singhal, S.1
-
63
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson PG et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003 348 2609 2617.
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
-
64
-
-
22044452126
-
Superiority of thalidomide and dexamethasone over vincristine- doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
-
Cavo M et al. Superiority of thalidomide and dexamethasone over vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood 2005 106 35 39.
-
(2005)
Blood
, vol.106
, pp. 35-39
-
-
Cavo, M.1
-
65
-
-
0037148921
-
A long-term study of prognosis in monoclonal gammopathy of undetermined significance
-
Kyle RA et al. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med 2002 346 564 569.
-
(2002)
N Engl J Med
, vol.346
, pp. 564-569
-
-
Kyle, R.A.1
-
66
-
-
10744223381
-
Genetics and cytogenetics of multiple myeloma: A workshop report
-
Fonseca R et al. Genetics and cytogenetics of multiple myeloma: a workshop report. Cancer Res 2004 64 1546 1558.
-
(2004)
Cancer Res
, vol.64
, pp. 1546-1558
-
-
Fonseca, R.1
-
67
-
-
0036796603
-
Molecular aspects of multiple myeloma
-
Pratt G. Molecular aspects of multiple myeloma. Mol Pathol 2002 55 273 283.
-
(2002)
Mol Pathol
, vol.55
, pp. 273-283
-
-
Pratt, G.1
-
69
-
-
0141993685
-
Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid cases
-
Smadja NV et al. Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid cases. Genes Chromosomes Cancer 2003 38 234 239.
-
(2003)
Genes Chromosomes Cancer
, vol.38
, pp. 234-239
-
-
Smadja, N.V.1
-
70
-
-
0141481984
-
The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
-
Fonseca R et al. The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma. Blood 2003 102 2562 2567.
-
(2003)
Blood
, vol.102
, pp. 2562-2567
-
-
Fonseca, R.1
-
71
-
-
13544275899
-
Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma
-
Wuilleme S et al. Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma. Leukemia 2005 19 275 278.
-
(2005)
Leukemia
, vol.19
, pp. 275-278
-
-
Wuilleme, S.1
-
72
-
-
24944584840
-
Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics
-
Cremer FW et al. Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics. Genes Chromosomes Cancer 2005 44 194 203.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 194-203
-
-
Cremer, F.W.1
-
73
-
-
0142151221
-
T(11;14) and t(4;14) translocations correlated with mature lymphoplasmacytoid and immature morphology, respectively, in multiple myeloma
-
Garand R Avet-Loiseau H Accard F Moreau P Harousseau JL Bataille R. t(11;14) and t(4;14) translocations correlated with mature lymphoplasmacytoid and immature morphology, respectively, in multiple myeloma. Leukemia 2003 17 2032 2035.
-
(2003)
Leukemia
, vol.17
, pp. 2032-2035
-
-
Garand, R.1
Avet-Loiseau, H.2
Accard, F.3
Moreau, P.4
Harousseau, J.L.5
Bataille, R.6
-
74
-
-
0036721371
-
Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy
-
Moreau P et al. Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy. Blood 2002 100 1579 1583.
-
(2002)
Blood
, vol.100
, pp. 1579-1583
-
-
Moreau, P.1
-
75
-
-
27144441760
-
Clinical implications of t (11;14(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy
-
Gertz MA et al. Clinical implications of t (11;14(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy. Blood 2005 106 2837 2840.
-
(2005)
Blood
, vol.106
, pp. 2837-2840
-
-
Gertz, M.A.1
-
77
-
-
2542499695
-
Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation
-
Kroger N et al. Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation. Blood 2004 103 4056 4061.
-
(2004)
Blood
, vol.103
, pp. 4056-4061
-
-
Kroger, N.1
-
78
-
-
0032147210
-
Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy
-
Drach J et al. Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy. Blood 1998 92 802 809.
-
(1998)
Blood
, vol.92
, pp. 802-809
-
-
Drach, J.1
-
79
-
-
11144219996
-
P53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation
-
Chang H Qi C Yi QL Reece D Stewart AK. p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation. Blood 2005 105 358 360.
-
(2005)
Blood
, vol.105
, pp. 358-360
-
-
Chang, H.1
Qi, C.2
Yi, Q.L.3
Reece, D.4
Stewart, A.K.5
-
80
-
-
0036493522
-
Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
-
Zhan F et al. Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells. Blood 2002 99 1745 1757.
-
(2002)
Blood
, vol.99
, pp. 1745-1757
-
-
Zhan, F.1
-
81
-
-
0037307238
-
Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development
-
Zhan F Tian E Bumm K Smith R Barlogie B Shaughnessy J Jr.. Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development. Blood 2003 101 1128 1140.
-
(2003)
Blood
, vol.101
, pp. 1128-1140
-
-
Zhan, F.1
Tian, E.2
Bumm, K.3
Smith, R.4
Barlogie, B.5
Shaughnessy Jr., J.6
-
83
-
-
0036014969
-
The enigma of ectopic expression of FGFR3 in multiple myeloma: A critical initiating event or just a target for mutational activation during tumor progression
-
Chesi M Bergsagel PL Kuehl WM. The enigma of ectopic expression of FGFR3 in multiple myeloma: a critical initiating event or just a target for mutational activation during tumor progression. Curr Opin Hematol 2002 9 288 293.
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 288-293
-
-
Chesi, M.1
Bergsagel, P.L.2
Kuehl, W.M.3
-
84
-
-
0037443417
-
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript
-
Santra M Zhan F Tian E Barlogie B Shaughnessy J Jr.. A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript. Blood 2003 101 2374 2376.
-
(2003)
Blood
, vol.101
, pp. 2374-2376
-
-
Santra, M.1
Zhan, F.2
Tian, E.3
Barlogie, B.4
Shaughnessy Jr., J.5
-
86
-
-
33645317151
-
A new molecular classification of multiple myeloma using gene expression profiling and fluorescence in situ hybridisation as predictor for event free survival
-
Hose D et al. A new molecular classification of multiple myeloma using gene expression profiling and fluorescence in situ hybridisation as predictor for event free survival. Blood 2004 104 [abstract 73].
-
(2004)
Blood
, vol.104
-
-
Hose, D.1
-
87
-
-
0038495926
-
Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I. interpretation in the context of global gene expression
-
Shaughnessy J et al. Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I. interpretation in the context of global gene expression. Blood 2003 101 3849 3856.
-
(2003)
Blood
, vol.101
, pp. 3849-3856
-
-
Shaughnessy, J.1
-
88
-
-
33645300432
-
Multiple myeloma: Global expression profiling indicates upregulation of the ribosomal machinery in hyperdiploid clones
-
Cremer FW et al. Multiple myeloma: global expression profiling indicates upregulation of the ribosomal machinery in hyperdiploid clones. Blood 2004 1004 [abstract 1421].
-
(2004)
Blood
, vol.1004
-
-
Cremer, F.W.1
-
90
-
-
0033971174
-
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors
-
Gu ZJ et al. Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors. Leukemia 2000 14 188 197.
-
(2000)
Leukemia
, vol.14
, pp. 188-197
-
-
Gu, Z.J.1
-
91
-
-
0034655957
-
Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma
-
Dankbar B et al. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma. Blood 2000 95 2630 2636.
-
(2000)
Blood
, vol.95
, pp. 2630-2636
-
-
Dankbar, B.1
-
92
-
-
0033134764
-
Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
-
Vacca A et al. Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood 1999 93 3064 3073.
-
(1999)
Blood
, vol.93
, pp. 3064-3073
-
-
Vacca, A.1
-
93
-
-
0027133422
-
Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion
-
Uchiyama H Barut BA Mohrbacher AF Chauhan D Anderson KC. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood 1993 82 3712 3720.
-
(1993)
Blood
, vol.82
, pp. 3712-3720
-
-
Uchiyama, H.1
Barut, B.A.2
Mohrbacher, A.F.3
Chauhan, D.4
Anderson, K.C.5
-
94
-
-
18544367201
-
NF-kappa B as a therapeutic target in multiple myeloma
-
Hideshima T et al. NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem 2002 277 16639 16647.
-
(2002)
J Biol Chem
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
-
95
-
-
1542720384
-
Cancer and the microenvironment: Myeloma-osteoclast interactions as a model
-
Yaccoby S et al. Cancer and the microenvironment: myeloma-osteoclast interactions as a model. Cancer Res 2004 64 2016 2023.
-
(2004)
Cancer Res
, vol.64
, pp. 2016-2023
-
-
Yaccoby, S.1
-
96
-
-
1442285889
-
Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
-
Hurt EM et al. Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma. Cancer Cell 2004 5 191 199.
-
(2004)
Cancer Cell
, vol.5
, pp. 191-199
-
-
Hurt, E.M.1
-
97
-
-
0037464332
-
Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3
-
Vande Broek I Asosingh K Vanderkerken K Straetmans N Van Camp B Van Riet I. Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3. Br J Cancer 2003 88 855 862.
-
(2003)
Br J Cancer
, vol.88
, pp. 855-862
-
-
Vande Broek, I.1
Asosingh, K.2
Vanderkerken, K.3
Straetmans, N.4
Van Camp, B.5
Van Riet, I.6
-
98
-
-
0037105599
-
Role for macrophage inflammatory protein (MIP) -1alpha and MIP-1 beta in the development of osteolytic lesions in multiple myeloma
-
Abe M et al. Role for macrophage inflammatory protein (MIP) -1alpha and MIP-1 beta in the development of osteolytic lesions in multiple myeloma. Blood 2002 100 2195 2202.
-
(2002)
Blood
, vol.100
, pp. 2195-2202
-
-
Abe, M.1
-
100
-
-
2342614186
-
Bone marrow endothelial cells increase the invasiveness of human multiple myeloma cells through upregulation of MMP-9: Evidence for a role of hepatocyte growth factor
-
Vande Broek I et al. Bone marrow endothelial cells increase the invasiveness of human multiple myeloma cells through upregulation of MMP-9: evidence for a role of hepatocyte growth factor. Leukemia 2004 18 976 982.
-
(2004)
Leukemia
, vol.18
, pp. 976-982
-
-
Vande Broek, I.1
-
101
-
-
0042008128
-
Survival and proliferation factors of normal and malignant plasma cells
-
Klein B et al. Survival and proliferation factors of normal and malignant plasma cells. Int J Hematol 2003 78 106 113.
-
(2003)
Int J Hematol
, vol.78
, pp. 106-113
-
-
Klein, B.1
-
102
-
-
0023849455
-
Autocrine generation and essential requirement of BSF-2/IL-6 for human multiple myeloma
-
Kawano M et al. Autocrine generation and essential requirement of BSF-2/IL-6 for human multiple myeloma. Nature 1988 332 83 85.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
-
103
-
-
0024503249
-
Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6
-
Klein B et al. Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6. Blood 1989 73 517 526.
-
(1989)
Blood
, vol.73
, pp. 517-526
-
-
Klein, B.1
-
104
-
-
0025861211
-
In vivo interleukin 6 gene expression in the tumoral environment in multiple myeloma
-
Portier M et al. In vivo interleukin 6 gene expression in the tumoral environment in multiple myeloma. Eur J Immunol 1991 21 1759 1762.
-
(1991)
Eur J Immunol
, vol.21
, pp. 1759-1762
-
-
Portier, M.1
-
105
-
-
33645290993
-
Survival and proliferation factors of human myeloma cells
-
In: *Bergsagel P.L.*Kuehl M..
-
Klein B et al. Survival and proliferation factors of human myeloma cells. In: Bergsagel PL Kuehl M, eds. Recent Advances in the Biology of Multiple Myeloma Totawa NJ: Humana Press 2003.
-
(2003)
Recent Advances in the Biology of Multiple Myeloma
-
-
Klein, B.1
-
106
-
-
1442332300
-
An inhibitor of the EGF receptor family blocks myeloma cell growt h factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis
-
Mahtouk K et al. An inhibitor of the EGF receptor family blocks myeloma cell growt h factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis. Blood 2004 103 1829 1837.
-
(2004)
Blood
, vol.103
, pp. 1829-1837
-
-
Mahtouk, K.1
-
107
-
-
11144355586
-
BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
-
Moreaux J et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 2004 103 3148 3157.
-
(2004)
Blood
, vol.103
, pp. 3148-3157
-
-
Moreaux, J.1
-
108
-
-
0037061757
-
Cooperation between heparin-binding EGF-like growth factor and interleukin-6 in promoting the growth of human myeloma cells
-
Wang YD et al. Cooperation between heparin-binding EGF-like growth factor and interleukin-6 in promoting the growth of human myeloma cells. Oncogene 2002 21 2584 2592.
-
(2002)
Oncogene
, vol.21
, pp. 2584-2592
-
-
Wang, Y.D.1
-
110
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta D Beerli RR Daly JM Hynes NE. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 1997 16 1647 1655.
-
(1997)
EMBO J
, vol.16
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
111
-
-
21144474918
-
Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells
-
Mahtouk K et al. Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells. Oncogene 2005 24 3512 3524.
-
(2005)
Oncogene
, vol.24
, pp. 3512-3524
-
-
Mahtouk, K.1
-
112
-
-
33645292104
-
Identification of intercellular communication signals involved in multiple myeloma with microarrays
-
Klein B et al. Identification of intercellular communication signals involved in multiple myeloma with microarrays. Haematologica/the hematology journal 2005 100.
-
(2005)
Haematologica/the Hematology Journal
, pp. 100
-
-
Klein, B.1
-
113
-
-
0032492879
-
Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells
-
Qiu Y Ravi L Kung HJ. Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells. Nature 1998 393 83 85.
-
(1998)
Nature
, vol.393
, pp. 83-85
-
-
Qiu, Y.1
Ravi, L.2
Kung, H.J.3
-
114
-
-
0035133050
-
Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells
-
Badache A Hynes NE. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells. Cancer Res 2001 61 383 391.
-
(2001)
Cancer Res
, vol.61
, pp. 383-391
-
-
Badache, A.1
Hynes, N.E.2
-
115
-
-
0038798673
-
Atypical expression of ErbB3 in myeloma cells: Cross-talk between ErbB3 and the interferon-alpha signaling complex
-
Walters DK French JD Arendt BK Jelinek DF. Atypical expression of ErbB3 in myeloma cells: cross-talk between ErbB3 and the interferon-alpha signaling complex. Oncogene 2003 22 3598 3607.
-
(2003)
Oncogene
, vol.22
, pp. 3598-3607
-
-
Walters, D.K.1
French, J.D.2
Arendt, B.K.3
Jelinek, D.F.4
-
116
-
-
18744384721
-
Small molecules with EGFR-TK inhibitor activity
-
Albanell J Gascon P. Small molecules with EGFR-TK inhibitor activity. Curr Drug Targets 2005 6 259 274.
-
(2005)
Curr Drug Targets
, vol.6
, pp. 259-274
-
-
Albanell, J.1
Gascon, P.2
-
117
-
-
0942298590
-
Expression of BCMA, TACI, and BAFF-R in multiple myeloma: A mechanism for growth and survival
-
Novak AJ et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 2004 103 689 694.
-
(2004)
Blood
, vol.103
, pp. 689-694
-
-
Novak, A.J.1
-
118
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
Tian E et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 2003 349 2483 2494.
-
(2003)
N Engl J Med
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
-
119
-
-
11144355390
-
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
-
Derksen PW et al. Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci USA 2004 101 6122 6127.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6122-6127
-
-
Derksen, P.W.1
-
120
-
-
18644386513
-
Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays
-
De Vos J et al. Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays. Oncogene 2002 21 6848 6857.
-
(2002)
Oncogene
, vol.21
, pp. 6848-6857
-
-
De Vos, J.1
-
121
-
-
22044435237
-
HB-EGF/HER-1 signaling in bone marrow mesenchymal stem cells: Inducing cell expansion and reversibly preventing multilineage differentiation
-
Krampera M et al. HB-EGF/HER-1 signaling in bone marrow mesenchymal stem cells: inducing cell expansion and reversibly preventing multilineage differentiation. Blood 2005 106 59 66.
-
(2005)
Blood
, vol.106
, pp. 59-66
-
-
Krampera, M.1
-
122
-
-
13544265673
-
Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation
-
Qin L et al. Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation. J Biol Chem 2005 280 3974 3981.
-
(2005)
J Biol Chem
, vol.280
, pp. 3974-3981
-
-
Qin, L.1
|