Isoform-specific Phosphorylation of Metabotropic Glutamate Receptor 5 by Protein Kinase C (PKC) Blocks Ca2+ Oscillation and Oscillatory Translocation of Ca2+-dependent PKC

Journal of Biological Chemistry

Volumn 279, Issue 3, 2004, Pages 2254-2261

  Uchino, Motoi ^a,b   Sakai, Norio ^a   Kashiwagi, Kaori ^a   Shirai, Yasuhito ^a   Shinohara, Yoshiaki ^c   Hirose, Kenzo ^d   Iino, Masamitsu ^d   Yamamura, Takehira ^b   Saito, Naoaki ^a,e  

^a KOBE UNIVERSITY   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

OSCILLATIONS; PROTEINS; SUBSTRATES;

CYCLICAL TRANSLOCATIONS; PLASMA MEMBRANES;

BIOCHEMISTRY;

ALANINE; ASPARTIC ACID; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE; MARCKS PROTEIN; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR 5A; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN KINASE C GAMMA; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CALCIUM SIGNALING; CELL MEMBRANE; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION;

CALCIUM SIGNALING; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; PROTEIN TRANSPORT; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, SMALL INTERFERING;

EID: 0345826019     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309894200     Document Type: Article

References (38)

1. Nakanishi, S., and Masu, M. (1994) Annu. Rev. Biophys. Biomol. Struct. 23, 319-348
2. Hollmann, M., and Heinemann, S. (1994) Annu Rev. Neurosci. 17, 31-108
3. Nishizuka, Y. (1984) Nature 308, 693-698
4. Berridge, M. J., and Irvine, R. F. (1984) Nature 312, 315-321
5. Kawabata, S., Kohara, A., Tsutsumi, R., Itahana, H., Hayashibe, S., Yamaguchi, T., and Okada, M. (1998) J. Biol. Chem. 273, 17381-17385
6. Kawabata, S., Tsutsumi, R., Kohara, A., Yamaguchi, T., Nakanishi, S., and Okada, M. (1996) Nature 383, 89-92
7. Nash, M. S., Schell, M. J., Atkinson, P. J., Johnston, N. R., Nahorski, S. R., and Challiss, R. A. (2002) J. Biol. Chem. 277, 35947-35960
8. Dale, L. B., Babwah, A. V., Bhattacharya, M., Kelvin, D. J., and Ferguson, S. S. (2001) J. Biol. Chem. 276, 35900-35908
9. Babwah, A. V., Dale, L. B., and Ferguson, S. S. G. (2003) J. Biol. Chem. 278, 5419-5426
10. Nishizuka, Y. (1988) Nature 334, 661-665
11. Nishizuka, Y. (1992) Science 258, 607-614
12. Osada, S., Mizuno, K., Saido, T. C., Suzuki, K., Kuroki, T., and Ohno, S. (1992) Mol. Cell. Biol. 12, 3930-3938
13. Ono, Y., Fujii, T., Ogita, K., Kikkawa, U., Igarashi, K., and Nishizuka, Y. (1988) J. Biol. Chem. 263, 6927-6932
14. Nishizuka, Y. (1995) FASEB J. 9, 484-496
15. Oancea, E., Teruel, M., Quest, A., and Meyer, T. (1998) J. Cell Biol. 140, 485-498
16. Sakai, N., Sasaki, K., Ikegaki N., Shirai, Y., and Saito, N. (1997) J. Cell Biol. 139, 1465-1476
17. Shirai, Y., Kashiwagi, K., Yagi, K., Sakai, N., and Saito, N. (1998) J. Cell Biol. 143, 511-521
18. Ohmori, S., Shirai, Y., Sakai, N., Fujii, M., Konishi, H., Kikkawa, U., and Saito, N. (1998) Mol. Cell. Biol. 18, 5263-5271
19. Kajimoto, T., Ohmori, S., Shirai, Y., Sakai, N., and Saito, N. (2001) Mol. Cell. Biol. 21, 1769-1783
20. Kashiwagi, K., Shirai, Y., Kuriyama, M., Sakai, N., and Saito, N. (2002) J. Biol. Chem. 277, 18037-18045
21. Ohmori, S., Sakai, N., Shirai, Y., Yamamoto, H., Miyamoto, E., Shimizu, N., and Saito, N. (2000) J. Biol. Chem. 275, 26449-26457
22. Hirose, K., Kadowaki, S., Tanabe, M., Takeshima, H., and Iino, M. (1999) Science 284, 1527-1530
23. Nakahara, K., Okada, M., and Nakanishi, S. (1997) J. Neurochem 69, 1467-1475
24. Irie, N., Sakai, N., Ueyama, T., Kajimoto, T., Shirai, Y., and Saito, N. (2002) Biochem. Biophys. Res. Commun. 298, 738-743
25. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001) Nature 411, 494-498
26. Ono, Y., Fujii, T., Igarashi, K., Kuno, T., Tanaka, C., Kikkawa, U., and Nishizuka, Y. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 4868-4871
27. Nishizuka, Y. (1986) Science 233, 305-312
28. Hajnoczky, G., Robb-Gaspers, L. D., Seitz, M. B., and Thomas, A. P. (1995) Cell 82, 41-424
29. Dolmetsch, R. E., Xu, K., and Lewis, R. S. (1998) Nature 392, 933-936
30. Gu, X., and Spitzer, N. C. (1995) Nature 375, 784-787
31. Codazzi, F., Teruel, M. N., and Meyer, T. (2001) Curr. Biol. 11, 1089-1097
32. Shirai, Y., Kashiwagi, K., Sakai, N., and Saito, N. (2000) J. Cell Sci. 113, 1335-1343
33. Oancea, E., and Meyer, T. (1998) Cell 95, 307-318
34. Aderem, A. A., Albert, K. A., Keum, M. M., Wang, J. K., Greengard, P., and Cohn, Z. A. (1988) Nature 332, 362-364
35. Aderem, A. (1992) Cell 71, 713-716
36. Blackshear, P. J. (1993) J. Biol. Chem. 268, 1501-1504
37. George, D., and Blackshear, P. (1992) J. Biol. Chem. 267, 24879-24885
38. Kligman, D., and Patel, J. (1986) J. Neurochem. 47, 298-303