Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis

Neurochemistry International

Volumn 46, Issue 3, 2005, Pages 227-234

  Sala, Gessica ^a   Beretta, Simone ^a   Ceresa, Chiara ^a,e   Mattavelli, Laura ^a,e   Zoia, Chiara ^a   Tremolizzo, Lucio ^a,e   Ferri, Alberto ^b,c   Carrì, Maria Teresa ^b,d   Ferrarese, Carlo ^a,e,f  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b Ctro Neurbio Sperim Mondino T   (Italy)

^c CNR Consiglio Nazionale delle Ricerche   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

^e SAN GERARDO HOSPITAL   (Italy)

^f SCIENTIFIC INSTITUTE   (Italy)

Author keywords

Amyotrophic lateral sclerosis; Antioxidants; Copper zinc superoxide dismutase; Excitotoxicity; Glutamate uptake; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMATE TRANSPORTER; ISOPROTEIN; MESSENGER RNA;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL LINE; CELL MUTANT; CONTROLLED STUDY; GENE MUTATION; GENETIC TRANSFECTION; GLIA CELL; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INTERMETHOD COMPARISON; NERVE CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SENSITIVITY ANALYSIS; WILD TYPE;

AMINO ACID TRANSPORT SYSTEM X-AG; AMYOTROPHIC LATERAL SCLEROSIS; ANTIOXIDANTS; BIOLOGICAL TRANSPORT, ACTIVE; BRAIN NEOPLASMS; CELL LINE, TUMOR; ELECTROPHORESIS, AGAR GEL; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; HUMANS; KINETICS; MUTATION; NEUROBLASTOMA; OXIDANTS; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM; SUPEROXIDE DISMUTASE; SYMPORTERS;

EID: 12744268071     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2004.10.002     Document Type: Article

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