Mammalian expression of full-length bovine aggrecan and link protein: Formation of recombinant proteoglycan aggregates and analysis of proteolytic cleavage by ADAMTS-4 and MMP-13

Biochimica et Biophysica Acta - General Subjects

Volumn 1760, Issue 3, 2006, Pages 472-486

  Miwa, Hazuki E ^a   Gerken, Thomas A ^a   Huynh, Tru D ^a   Flory, David M ^a   Hering, Thomas M ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ADAMTS 4; Aggrecan; Aggrecanase; Aggrecanolysis; Link protein; MMP 13; Proteoglycan aggregate

Indexed keywords

AGGRECAN; CHONDROITIN ABC LYASE; CHONDROITIN SULFATE; COLLAGENASE 3; GLYCOSAMINOGLYCAN; HYALURONIC ACID; LINK PROTEIN; METALLOPROTEINASE; MONOMER; PROTEIN P40; PROTEIN P68; PROTEOGLYCAN; RECOMBINANT PROTEIN; SERINE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN COS7; CONTROLLED STUDY; COW; GEL FILTRATION CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION;

ADAM PROTEINS; AGGRECANS; AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, GEL; COLLAGENASES; COS CELLS; EXTRACELLULAR MATRIX PROTEINS; GLYCOSAMINOGLYCANS; HUMANS; LECTINS, C-TYPE; MATRIX METALLOPROTEINASE 13; PROCOLLAGEN N-ENDOPEPTIDASE; PROTEOCHONDROITIN SULFATES; RECOMBINANT PROTEINS;

ANIMALIA; BOVINAE; MAMMALIA;

EID: 33644912865     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2005.12.003     Document Type: Article

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