Loss of endothelium-derived nitric oxide in rabbit aorta by oxidant stress: Restoration by superoxide dismutase mimetics

British Journal of Pharmacology

Volumn 124, Issue 4, 1998, Pages 719-728

  MacKenzie, Andrew ^a   Martin, William ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Endothelium; Nitric oxide; Oxidant stress; Rabbit aorta; Superoxide anion; Superoxide dismutase; Superoxide dismutase mimetics

Indexed keywords

ACETYLCHOLINE; COPPER SULFATE; DIETHYLDITHIOCARBAMIC ACID; HYPOXANTHINE; MANGANESE CHLORIDE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

ANIMAL TISSUE; ARTICLE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; SPIN TRAPPING; THORACIC AORTA;

ACETYLCHOLINE; ANIMALS; AORTA, THORACIC; DITIOCARB; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; HYPOXANTHINE; MALE; METALLOPORPHYRINS; MOLECULAR MIMICRY; MUSCLE RELAXATION; NITRIC OXIDE; OXIDATIVE STRESS; RABBITS; SUPEROXIDE DISMUTASE; XANTHINE;

EID: 0031806185     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701899     Document Type: Article

References (33)

1. AKAIKE, T., YOSHIDA, M., MIYAMOTO, Y., SATO, K., KOHNO, M., SASAMOTO, K., MIYAZAKI, K., UEDA, S. & MAEDA, H. (1993). Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/NO through a radical reaction. Biochemistry, 32, 827-832.
2. 4. J. Inorg. Biochem., 60, 133-148.
3. BEYER, W.F., JR. & FRIDOVICH, I. (1990). Superoxide dismutase mimic prepared from desferrioxamine and manganese dioxide. Methods Enzymol., 186, 242-249.
4. BOULOMIE, A., BAUERSACHS, J., LINZ, W., SCHOLKENS, B.A., WIEMER, G., FLEMING, I. & BUSSE, R. (1997). Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production. Hypertension, 30, 934-941.
5. CHERRY, P.D., OMAR, H.A., FARRELL, K.A., STUART, J.S. & WOLIN, M.S. (1990). Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation. Am. J. Physiol., 259, H1056-H1062.
6. COCCO, D., CALABRESE, L., RIGO, A., ARGESE, E. & ROTILIO, G. (1981). Re-examination of the reaction of diethyldithiocarbamate with the copper of superoxide dismutase. J. Biol. Chem., 256, 8983-8986.
7. DOWNEY, J.M. (1990). Free radicals and their involvement during long-term myocardial ischemia and reperfusion. Ann. Rev. Physiol., 52, 487-504.
8. EWING, J.F. & JANERO, D.R. (1995). Microplate superoxide dismutase assay employing a nonenzymatic superoxide generator. Anal. Biochem., 232, 243-248.
9. FAULKNER, K.M., LIOCHEV, S.I. & FRIDOVICH, I. (1994). Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J. Biol. Chem., 269, 23471-23476.
10. FRIDOVICH, I. (1983). Superoxide radical: an endogenous toxicant. Ann. Rev. Pharmacol. Toxicol., 23, 239-257.
11. GARDNER, P.R., NGUYEN, D.D.H. & WHITE, C.W. (1996). Superoxide scavenging by Mn(II/III) tetrakis (1-methyl-4-pyridyl) porphyrin in mammalian cells. Arch. Biochem. Biophys., 325, 20-28.
12. GRUNFELD, S., HAMILTON, C.A., MESAROS, S., MCCLAIN, S.W., DOMINICZAK, A.F., BOHR, D.F. & MALINSKI, T. (1995). Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension, 26, 854-857.
13. GRYGLEWSKI, R.J., PALMER, R.M.J. & MONCADA, S. (1986). Superoxide union is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature, 320, 454-456.
14. HATTORI, Y. KAWASAKI, H., ABE, K. & KANNO, M. (1991). Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta. Am. J. Physiol., 261, H1086-H1094.
15. HUBER, K.R., SRIDHAR, R. GRIFFITH, E.H. AMMA, E.L. & ROBERTS, J. (1987). Superoxide dismutase-like activities of copper(II) complexes tested in serum. Biochim. Biophys. Acta, 915, 267-276.
16. KAMATA, K. & KOBAYASHI, T. (1996). Changes in superoxide dismutase mRNA expression by streptozotocin-induced diabetes. Br. J. Pharmacol., 119, 583-589.
17. KATZ, S.D. SCHWARZ, M., YUEN, J. & LEJEMTEL, T.H. (1993). Impaired acetylcholine-mediated vasodilation in patients with congestive heart failure: Role of endothelium-derived vasodilating and vasocontricting factors. Circulation. 88, 55-61.
18. KELNER, M.J., BAGNELL, R., HALE, B. & ALEXANDER, N.M. (1989). Inactivation of intracellular copper-zinc superoxide dismutase by copper chelating agents without glutathione depletion and methemoglobin formation. Free Radical Biol. Med., 6, 355-360.
19. LEDENEV, A.N., KONSTANTINOV, A.A., POPOVA, E. & RUUGE, E.K. (1986). A simple assay of the superoxide generation rate with tiron as an ESP-visible radical scavenger. Biochem. Int., 13, 391-396.
20. MACKENZIE, A. & MARTIN, W. (1997). Assessment of superoxide dismutase mimetic compounds in the rabbit aorta. Br. J. Pharmacol., 122, 195P.
21. MACKENZIE, A. & MARTIN, W. (1988). A superoxide dismutase mimetic protects acetylcholine-induced relaxation from oxidant stress in the rabbit aorta. Br. J. Pharmacol., 123, 10P.
22. MOK, J.S.L., PAISLEY, K. & MARTIN, W. (1998). Inhibition of nitrergic neurotransmission in the bovine retractor penis muscle by an oxidant stress: effects of superoxide dismutase mimetics. Br. J. Pharmacol., (in press).
23. MCMURRAY, J., MCLAY, J., CHOPRA, M., BRIDGES, A. & BELCH, J.J.F. (1990). Evidence for enhanced free radical activity in chronic congestive heart failure secondary to coronary artery disease. Am J. Cardiol., 65, 1261-1262.
24. MIAN, K.B. & MARTIN, W. (1995). Differential sensitivity of basal and acetylcholine-stimulated activity of nitric oxide to destruction by superoxide union in rat aorta. Br. J. Pharmacol., 115, 993-1000.
25. MITCHELL, J.B., SAMUNI, A., KRISHNA, M.C., DEGRAFF, W.G., AHN, M.S., SAMUNI, U. & RUSSO, A. (1990). Biologically active metal-independent superoxide dismutase mimics. Biochemistry, 29, 2802-2807.
26. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev., 43, 109-142.
27. MÜGGE, A., ELWELL, J.H., PETERSON, T.E. & HARRISON, D.G. (1991). Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutuse activity. Am. J. Physiol., 260, C219-C225.
28. NAKAZONO, K., WATANABE, N., MATSUNO, K., SASAKI, J., SATO, T. & INOUE, M. (1991). Does superoxide underlie the pathogenesis of hypertension? Proc. Natl. Acad. Sci. U.S.A., 88, 10045-10048.
29. OHARA, Y., PETERSON, T.E. & HARRISON, D.G. (1993). Hypercholesterolemia increases endothelial superoxide union production. J. Clin. Invest., 91, 2546-2551.
30. OMAR, H.A., CHERRY, P.D., MORTELLITI, M.P., BURKE-WOLIN, T. & WOLIN, M.S. (1991). Inhibition of coronary artery superoxide dismutase atenuates endothelium-dependent and-independent nitrovasodilator relaxation. Circ. Res., 69, 601-608.
31. PLANE, F., WIGMORE, S., ANGELINI, G.D. & JEREMY, J.Y. (1997). Effect of copper on nitric oxide synthase and guanylyl cyclase activity in the rat isolated aorta. Br. J. Pharmacol., 121, 345-350.
32. SHARMA, R.C., CRAWFORD, D.W., KRAMSCH, D.M., SEVANIAN, A. & JIAO, Q. (1992). Immunolocalization of native antioxidant scavenger enzymes in early hypertensive and atherosclerotic arteries: Role of oxygen free radicals. Arterioscler. Thromb., 12, 403-415.
33. SORENSON, J.R.J. (1995). Pharmacological activities of copper compounds. In Handbook of Metal Ligand Interactions in Biological Fluids, ed. Berthon, G. pp. 1128-1139. New York: Marcel Dekker Inc.