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Volumn 38, Issue 2, 1998, Pages 89-102

Angiogenic factors in diabetic ocular disease: Mechanisms of today, therapies for tomorrow

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; ADENOSINE; ANGIOGENESIS INHIBITOR; ANGIOGENIN; ANGIOPOIETIN 1; ANGIOPOIETIN 2; BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; FIBRIN; GROWTH FACTOR; GROWTH HORMONE; INTEGRIN; PLASMINOGEN ACTIVATOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 0031867565     PISSN: 00208167     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004397-199803820-00007     Document Type: Review
Times cited : (26)

References (87)
  • 1
    • 0030806436 scopus 로고    scopus 로고
    • Angiogenesis: New aspects relating to its initiation and control
    • Norrby K. Angiogenesis: new aspects relating to its initiation and control. APMIS 1997;105:417-437
    • (1997) APMIS , vol.105 , pp. 417-437
    • Norrby, K.1
  • 2
    • 0022648938 scopus 로고
    • How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture
    • Folkman J. How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture. Cancer Res 1986;46:467-473
    • (1986) Cancer Res , vol.46 , pp. 467-473
    • Folkman, J.1
  • 3
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-1186
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 4
    • 0024426525 scopus 로고
    • Angiogenic properties of normal and psoriatic skin associated with epidermis, not dermis
    • Mahlotra R, Stenn KS, Fernandez LA, Braverman IM. Angiogenic properties of normal and psoriatic skin associated with epidermis, not dermis. Lab Invest 1989;61:162-165
    • (1989) Lab Invest , vol.61 , pp. 162-165
    • Mahlotra, R.1    Stenn, K.S.2    Fernandez, L.A.3    Braverman, I.M.4
  • 6
    • 0002451749 scopus 로고
    • Vision disorders in diabetes. National Diabetes Data Group
    • (NIH publ. no. 85-1468). Bethesda, MD: US Department of Health and Human Services
    • Klein R, Klein BEK. Vision disorders in diabetes. In: National Diabetes Data Group. Diabetes in America: Diabetes Data Compiled 1984. (NIH publ. no. 85-1468). Bethesda, MD: US Department of Health and Human Services 1985:1-2
    • (1985) Diabetes in America: Diabetes Data Compiled 1984 , pp. 1-2
    • Klein, R.1    Klein, B.E.K.2
  • 7
    • 0026339086 scopus 로고
    • Detecting and treating retinopathy in patients with type 1 diabetes mellitus
    • Javitt JC, Aiello LP, Bassi LJ, et al. Detecting and treating retinopathy in patients with type 1 diabetes mellitus. Ophthalmology 1991;98:1565-1574
    • (1991) Ophthalmology , vol.98 , pp. 1565-1574
    • Javitt, J.C.1    Aiello, L.P.2    Bassi, L.J.3
  • 8
    • 0028074463 scopus 로고
    • Preventive eye care in people with diabetes is cost saving to the federal government
    • Javitt JC, Aiello LP, Chiang YP, et al. Preventive eye care in people with diabetes is cost saving to the federal government. Diabetes Care 1994;17:909-917
    • (1994) Diabetes Care , vol.17 , pp. 909-917
    • Javitt, J.C.1    Aiello, L.P.2    Chiang, Y.P.3
  • 9
    • 0028896755 scopus 로고
    • The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XV. The long-term incidence of macular edema
    • Klein R, et al. The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XV. The long-term incidence of macular edema. Ophthalmology 1995;102:7-16
    • (1995) Ophthalmology , vol.102 , pp. 7-16
    • Klein, R.1
  • 10
    • 0024497878 scopus 로고
    • Cost effectiveness of current approaches to the control of retinopathy in Type 1 diabetics
    • Javitt JC, Canner JK, Sommer A. Cost effectiveness of current approaches to the control of retinopathy in Type 1 diabetics. Ophthalmology 1989;96:255-264
    • (1989) Ophthalmology , vol.96 , pp. 255-264
    • Javitt, J.C.1    Canner, J.K.2    Sommer, A.3
  • 11
    • 0021136256 scopus 로고
    • The Wisconsin Epidemiologic Study of Diabetic Retinopathy: II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years
    • Klein R, Klein BE, Moss SE, et al. The Wisconsin Epidemiologic Study of Diabetic Retinopathy: II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol 1984;102:520-526
    • (1984) Arch Ophthalmol , vol.102 , pp. 520-526
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3
  • 12
    • 0345512093 scopus 로고
    • Photocoagulation of proliferative diabetic retinopathy [Diabetic Retinopathy Study rep No. 2
    • Diabetic Retinopathy Study Group Photocoagulation of proliferative diabetic retinopathy [Diabetic Retinopathy Study rep No. 2. Ophthalmology 1978;85:82
    • (1978) Ophthalmology , vol.85 , pp. 82
  • 13
    • 0025892104 scopus 로고
    • Early photocoagulation for diabetic retinopathy [ETDRS rep. no. 9]
    • Early Treatment Diabetic Retinopathy Study Group. Early photocoagulation for diabetic retinopathy [ETDRS rep. no. 9]. Ophthalmology 1991;98:766-785
    • (1991) Ophthalmology , vol.98 , pp. 766-785
  • 14
    • 0000230096 scopus 로고    scopus 로고
    • The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal disease
    • Michaelson IC. The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal disease. Trans Ophthalmol Soc UK 1998;68:137-180
    • (1998) Trans Ophthalmol Soc UK , vol.68 , pp. 137-180
    • Michaelson, I.C.1
  • 15
    • 0003100257 scopus 로고
    • Retinal vascularization in health and disease
    • Ashton N. Retinal vascularization in health and disease. Am J Ophthalmol 1957;44:7-24
    • (1957) Am J Ophthalmol , vol.44 , pp. 7-24
    • Ashton, N.1
  • 16
    • 0029121235 scopus 로고
    • Angiogenesis: Mechanistic insights, neovascular diseases, and therapeutic prospects
    • Battegay EJ. Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects. Mol Med 1995;73:333-346
    • (1995) Mol Med , vol.73 , pp. 333-346
    • Battegay, E.J.1
  • 17
    • 0024339705 scopus 로고
    • The heparin binding (fibroblast) growth factor family of proteins
    • Burgess WH, Maciag T. The heparin binding (fibroblast) growth factor family of proteins. Ann Rev Biochem 1989;58:575-606
    • (1989) Ann Rev Biochem , vol.58 , pp. 575-606
    • Burgess, W.H.1    Maciag, T.2
  • 18
    • 0005911475 scopus 로고
    • Endothelial cell-derived basic fibroblast growth factor: Synthesis and deposition into subendothelial extracellular matrix
    • Vlodavsky I, Folkman J, Sullivan R, et al. Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix. Proc Natl Acad Sci USA 1987;84(8):2292-2296
    • (1987) Proc Natl Acad Sci USA , vol.84 , Issue.8 , pp. 2292-2296
    • Vlodavsky, I.1    Folkman, J.2    Sullivan, R.3
  • 19
    • 0026687865 scopus 로고
    • Basic fibroblast growth factor (bFGF) immunolocalization in the rodent outer retina demonstrated with an anti-rodent bFGF antibody
    • Gao H, Hollyfield JG. Basic fibroblast growth factor (bFGF) immunolocalization in the rodent outer retina demonstrated with an anti-rodent bFGF antibody. Brain Res 1992;585:355-360
    • (1992) Brain Res , vol.585 , pp. 355-360
    • Gao, H.1    Hollyfield, J.G.2
  • 20
    • 2442549663 scopus 로고
    • Basic fibroblast growth factor induces angiogenesis in vitro
    • Montesano R, Vassali JD, Baird A, et al. Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci USA 1986;83:7297-7301
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7297-7301
    • Montesano, R.1    Vassali, J.D.2    Baird, A.3
  • 21
    • 0022382632 scopus 로고
    • Angiogenesis is stimulated by a tumor-derived endothelial cell growth factor
    • Shing Y, Folkman J, Haudenschild C, et al. Angiogenesis is stimulated by a tumor-derived endothelial cell growth factor. J Cell Biochem 1985;29:275-287
    • (1985) J Cell Biochem , vol.29 , pp. 275-287
    • Shing, Y.1    Folkman, J.2    Haudenschild, C.3
  • 22
    • 0022457546 scopus 로고
    • Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast a growth factor
    • Abraham JA, Mergia A, Whang JL, et al. Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast a growth factor. Science 1986;233:545-548
    • (1986) Science , vol.233 , pp. 545-548
    • Abraham, J.A.1    Mergia, A.2    Whang, J.L.3
  • 23
    • 0025913891 scopus 로고
    • Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma
    • Kandel J, Bossy-Wetzel E, Radvany F, et al. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell 1991;66: 1095-1104
    • (1991) Cell , vol.66 , pp. 1095-1104
    • Kandel, J.1    Bossy-Wetzel, E.2    Radvany, F.3
  • 24
    • 0024352333 scopus 로고
    • Growth factors are released by mechanically wounded endothelial cells
    • McNeil PL, Muthukrishman L, Warder E, D'Amore PA. Growth factors are released by mechanically wounded endothelial cells. J Cell Biol 1989;109(2):811-822
    • (1989) J Cell Biol , vol.109 , Issue.2 , pp. 811-822
    • McNeil, P.L.1    Muthukrishman, L.2    Warder, E.3    D'Amore, P.A.4
  • 25
    • 0025294817 scopus 로고
    • Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy
    • Sivalingam A, Kenney J, Brown GC, et al. Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol 1990;108:869-872
    • (1990) Arch Ophthalmol , vol.108 , pp. 869-872
    • Sivalingam, A.1    Kenney, J.2    Brown, G.C.3
  • 26
    • 0027053487 scopus 로고
    • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    • Pepper M, Ferrara N, Orci L, Montesano R. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Comm 1992;189:824-831
    • (1992) Biochem Biophys Res Comm , vol.189 , pp. 824-831
    • Pepper, M.1    Ferrara, N.2    Orci, L.3    Montesano, R.4
  • 27
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219:983-985
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3
  • 28
    • 0024801035 scopus 로고
    • Vascular permeability factor, an endothelial cell mitogen related to PDGF
    • Keck PJ, Hauser SD, Krivi G. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989;246:1309-1312
    • (1989) Science , vol.246 , pp. 1309-1312
    • Keck, P.J.1    Hauser, S.D.2    Krivi, G.3
  • 29
    • 0024818355 scopus 로고
    • Vascular Permeability factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kunang WJ. Vascular Permeability factor is a secreted angiogenic mitogen. Science 1989;246:1306-1309
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kunang, W.J.3
  • 30
    • 15644366961 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective Beta isoform-selective inhibitor
    • Aiello LP, Bursell SE, Clermont A, et al. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective Beta isoform-selective inhibitor. Diabetes 1997;46:1473-1480
    • (1997) Diabetes , vol.46 , pp. 1473-1480
    • Aiello, L.P.1    Bursell, S.E.2    Clermont, A.3
  • 31
    • 0028883260 scopus 로고
    • Comparative analysis of vascular endothelial growth factor (VEGF) receptors on retinal and aortic microvascular endothelial cells
    • Thieme H, Aiello LP, Takagi H, et al. Comparative analysis of vascular endothelial growth factor (VEGF) receptors on retinal and aortic microvascular endothelial cells. Diabetes 1994;44:98-103
    • (1994) Diabetes , vol.44 , pp. 98-103
    • Thieme, H.1    Aiello, L.P.2    Takagi, H.3
  • 32
    • 0028826101 scopus 로고
    • Hypoxic regulation of vascular endothelial growth factor in retinal cells
    • Aiello LP, Northrup JM, Keyt BA, et al. Hypoxic regulation of vascular endothelial growth factor in retinal cells. Arch Ophthalmol 1995;113(12):1538-1544
    • (1995) Arch Ophthalmol , vol.113 , Issue.12 , pp. 1538-1544
    • Aiello, L.P.1    Northrup, J.M.2    Keyt, B.A.3
  • 33
    • 0028786651 scopus 로고
    • Inhibition of vascular endothelial growth factor suppresses retinal neovascularization in vivo
    • Aiello LP, Pierce EA, Foley ED, et al. Inhibition of vascular endothelial growth factor suppresses retinal neovascularization in vivo. Proc Natl Acad Sci USA 1995;92(23):10457-10461
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.23 , pp. 10457-10461
    • Aiello, L.P.1    Pierce, E.A.2    Foley, E.D.3
  • 34
    • 0030013610 scopus 로고    scopus 로고
    • Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy
    • Robinson GS, Pierce EA, Rook SL, et al. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy. Proc Natl Acad Sci USA 1996; 93:4851-4856
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4851-4856
    • Robinson, G.S.1    Pierce, E.A.2    Rook, S.L.3
  • 35
    • 0030067257 scopus 로고    scopus 로고
    • Inhibition of VEGF prevent ocular neovascularization in a non-human primate
    • Adamis A, et al. Inhibition of VEGF prevent ocular neovascularization in a non-human primate. Arch Ophthalmol 1996;114:66-71
    • (1996) Arch Ophthalmol , vol.114 , pp. 66-71
    • Adamis, A.1
  • 36
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal diseases
    • Aiello LP, Avery RL, Arrigg OG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal diseases. N Engl J Med 1994;331: 1480-1487
    • (1994) N Engl J Med , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, O.G.3
  • 37
    • 0029739621 scopus 로고    scopus 로고
    • Localization of VEGF in human retina and choroid
    • Lutty GA, McLeod DS, Merges C, et al. Localization of VEGF in human retina and choroid. Arch Ophthalmol 1996;114:971-977
    • (1996) Arch Ophthalmol , vol.114 , pp. 971-977
    • Lutty, G.A.1    McLeod, D.S.2    Merges, C.3
  • 38
    • 0031018867 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathy
    • Amin RH, Frank RN, Kennedy A, et al. Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 1997;38:36-47
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 36-47
    • Amin, R.H.1    Frank, R.N.2    Kennedy, A.3
  • 39
    • 0030770396 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and severity of nonproliferative diabetic retinopathy (NPDR) mediate retinal hemodynamics in vivo: A potential role for VEGF in the progression of nonproliferative diabetic retinopathy
    • Clermont A, Aiello LP, Mori F, et al. Vascular endothelial growth factor (VEGF) and severity of nonproliferative diabetic retinopathy (NPDR) mediate retinal hemodynamics in vivo: A potential role for VEGF in the progression of nonproliferative diabetic retinopathy. Am J Ophthalmol 1997;124:433-446
    • (1997) Am J Ophthalmol , vol.124 , pp. 433-446
    • Clermont, A.1    Aiello, L.P.2    Mori, F.3
  • 40
    • 0028879632 scopus 로고
    • Blood-ocular barrier breakdown in eyes with ocular melanoma. A potential role for vascular endothelial growth factor/vascular permeability factor
    • Vinores SA, Kuchle M, Mahlow J, et al. Blood-ocular barrier breakdown in eyes with ocular melanoma. A potential role for vascular endothelial growth factor/vascular permeability factor. Am J Pathol 1995;147:1289-1297
    • (1995) Am J Pathol , vol.147 , pp. 1289-1297
    • Vinores, S.A.1    Kuchle, M.2    Mahlow, J.3
  • 41
    • 0029879849 scopus 로고    scopus 로고
    • Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes
    • Lopez PF, Sippy BD, Lambert HM, et al. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Invest Opthalmol Vis Sci 1996;37:855-868
    • (1996) Invest Opthalmol Vis Sci , vol.37 , pp. 855-868
    • Lopez, P.F.1    Sippy, B.D.2    Lambert, H.M.3
  • 42
    • 2642709170 scopus 로고    scopus 로고
    • Characterization of vascular endothelial growth factor's effect on the activation of phospholipase Cγ protein kinase C pathways and endothelial cell growth
    • Pu X, Aiello LP, Jiang ZY, et al. Characterization of vascular endothelial growth factor's effect on the activation of phospholipase Cγ protein kinase C pathways and endothelial cell growth. J Clin Invest 1996;98:2018-326
    • (1996) J Clin Invest , vol.98 , pp. 2018-2326
    • Pu, X.1    Aiello, L.P.2    Jiang, Z.Y.3
  • 43
    • 13344293711 scopus 로고    scopus 로고
    • Amelioration of vascular dysfunction in diabetic rats by an oral PKC β inhibitor
    • Ishii H, et al. Amelioration of vascular dysfunction in diabetic rats by an oral PKC β inhibitor. Science 1996;272:728-731
    • (1996) Science , vol.272 , pp. 728-731
    • Ishii, H.1
  • 44
    • 85047503908 scopus 로고
    • The houssay phenomenon in man: Recovery from retinopathy in a case of diabetes with Simmonds' disease
    • Poulsen JE. The houssay phenomenon in man: recovery from retinopathy in a case of diabetes with Simmonds' disease. Diabetes 1958;2:7-12
    • (1958) Diabetes , vol.2 , pp. 7-12
    • Poulsen, J.E.1
  • 45
    • 0013882121 scopus 로고
    • Diabetes and anterior pituitary insufficiency: Final course and postmortem study of a diabetic patient with Sheehan's syndrome
    • Poulsen JE. Diabetes and anterior pituitary insufficiency: final course and postmortem study of a diabetic patient with Sheehan's syndrome. Diabetes 1966;15:73-77
    • (1966) Diabetes , vol.15 , pp. 73-77
    • Poulsen, J.E.1
  • 46
    • 0017704479 scopus 로고
    • Prolonged follow-up in diabetic retinopathy treated by sectioning the pituitary stalk
    • Zimmerman BR, Molnar GD. Prolonged follow-up in diabetic retinopathy treated by sectioning the pituitary stalk. Mayo Clin Proc 1977;52:233-237
    • (1977) Mayo Clin Proc , vol.52 , pp. 233-237
    • Zimmerman, B.R.1    Molnar, G.D.2
  • 47
    • 0018104186 scopus 로고
    • Metabolic and clinical studies in growth hormone deficient dwarfs: A ten year follow-up
    • Merimee TJ. Metabolic and clinical studies in growth hormone deficient dwarfs: a ten year follow-up. N Engl J Med 1978;298:1217-1222
    • (1978) N Engl J Med , vol.298 , pp. 1217-1222
    • Merimee, T.J.1
  • 48
    • 0017337542 scopus 로고
    • Retinopathy and plasma growth hormone levels in idiopathic hemochromatosis with diabetes
    • Passa R, Rousselie F, Gauville C, Canivet J. Retinopathy and plasma growth hormone levels in idiopathic hemochromatosis with diabetes. Diabetes 1977;26:113-120
    • (1977) Diabetes , vol.26 , pp. 113-120
    • Passa, R.1    Rousselie, F.2    Gauville, C.3    Canivet, J.4
  • 49
    • 0021349457 scopus 로고
    • Growth hormone and endothelial function during exercise in diabetics with and without retinopathy
    • Sundkvist G, Almer L, Pandolfi M. Growth hormone and endothelial function during exercise in diabetics with and without retinopathy. Acta Med Scand 1984;215:55-61
    • (1984) Acta Med Scand , vol.215 , pp. 55-61
    • Sundkvist, G.1    Almer, L.2    Pandolfi, M.3
  • 50
    • 0020550445 scopus 로고
    • Insulin-like growth factors: Studies in diabetics with and with retinopathy
    • Merimee TJ, Zapf J, Groesch ER. Insulin-like growth factors: studies in diabetics with and with retinopathy. N Engl J Med 1983;309:527-530
    • (1983) N Engl J Med , vol.309 , pp. 527-530
    • Merimee, T.J.1    Zapf, J.2    Groesch, E.R.3
  • 51
    • 0026343661 scopus 로고
    • Association of elevated IGF-1 levels with increased retinopathy in late-onset diabetes
    • Dills DG, Moss SE, Klein R, Klein BE. Association of elevated IGF-1 levels with increased retinopathy in late-onset diabetes. Diabetes 1991;40:1724-1730
    • (1991) Diabetes , vol.40 , pp. 1724-1730
    • Dills, D.G.1    Moss, S.E.2    Klein, R.3    Klein, B.E.4
  • 52
    • 0022539028 scopus 로고
    • Insulin-like growth factors in vitreous: Studies in controls and diabetics with neovascularization
    • Grant MB, Russel B, Fitgerald C, Merimee TJ. Insulin-like growth factors in vitreous: studies in controls and diabetics with neovascularization. Diabetes 1986;35:416-420
    • (1986) Diabetes , vol.35 , pp. 416-420
    • Grant, M.B.1    Russel, B.2    Fitgerald, C.3    Merimee, T.J.4
  • 53
    • 0028944958 scopus 로고
    • Does insulin-like growth factor 1 predict incidence and progression of diabetic retinopathy
    • Wang Q, Dills DG, Klein R, et al. Does insulin-like growth factor 1 predict incidence and progression of diabetic retinopathy. Diabetes 1995;44:161-164
    • (1995) Diabetes , vol.44 , pp. 161-164
    • Wang, Q.1    Dills, D.G.2    Klein, R.3
  • 54
    • 0025366074 scopus 로고
    • Insulin-like growth factor I stimulates prolifertion, migration, and plasminogen activator release by human retinal pigment epithelial cells
    • Grant MB, Guay C, Marsh R. Insulin-like growth factor I stimulates prolifertion, migration, and plasminogen activator release by human retinal pigment epithelial cells. Curr Eye Res 1990;9:323-335
    • (1990) Curr Eye Res , vol.9 , pp. 323-335
    • Grant, M.B.1    Guay, C.2    Marsh, R.3
  • 55
    • 0027433439 scopus 로고
    • Insulin-like growth factor I as an antiangiogenic agent: In vivo and vitro studies
    • Grant MB, Mames RN, Fitgerals C, et al. Insulin-like growth factor I as an antiangiogenic agent: in vivo and vitro studies. Ann NY Acad Sci 1993;692:230-242
    • (1993) Ann NY Acad Sci , vol.692 , pp. 230-242
    • Grant, M.B.1    Mames, R.N.2    Fitgerals, C.3
  • 56
    • 0030863133 scopus 로고    scopus 로고
    • Essential role of growth hormone in ischemia-induced retinal neovascularization
    • Smith LEH, Kopchick JJ, Chen W, et al. Essential role of growth hormone in ischemia-induced retinal neovascularization. Science 1997;276:1706-1709
    • (1997) Science , vol.276 , pp. 1706-1709
    • Smith, L.E.H.1    Kopchick, J.J.2    Chen, W.3
  • 57
    • 0026770377 scopus 로고
    • Integrins: Versality, modulation and signaling in cell adhesion
    • Hynes RO. Integrins: versality, modulation and signaling in cell adhesion. Cell 1992;69: 11-25
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 58
    • 0027459771 scopus 로고
    • Signal transduction from the extracellular matrix
    • Juliano RL, Haskill S. Signal transduction from the extracellular matrix. J Cell Biol 1993; 120:577-585
    • (1993) J Cell Biol , vol.120 , pp. 577-585
    • Juliano, R.L.1    Haskill, S.2
  • 60
    • 0027982162 scopus 로고    scopus 로고
    • Integrins as dynamic regulators of vascular function
    • Luscinskas FW, Lawler J. Integrins as dynamic regulators of vascular function. FASEB J 1996;8:929-938
    • (1996) FASEB J , vol.8 , pp. 929-938
    • Luscinskas, F.W.1    Lawler, J.2
  • 62
    • 0030635917 scopus 로고    scopus 로고
    • vβ5 in angiogenesis
    • Goldberg ID, Rosen EM, eds. Basel: Birkhauser Verlag
    • vβ5 in angiogenesis. In: Goldberg ID, Rosen EM, eds. Regulation of angiogenesis. Basel: Birkhauser Verlag, 1997:361-390
    • (1997) Regulation of Angiogenesis , pp. 361-390
    • Varner, J.A.1
  • 63
    • 0001254182 scopus 로고
    • Integrins: Structure, function and biological properties
    • Cheresh D. Integrins: structure, function and biological properties. Adv Mol Cell Biol 1993;6:225-252
    • (1993) Adv Mol Cell Biol , vol.6 , pp. 225-252
    • Cheresh, D.1
  • 64
    • 0028801218 scopus 로고
    • Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules
    • Miyamoto S, Teramoto H, Coso OA, et al. Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol 1995;131:791-805
    • (1995) J Cell Biol , vol.131 , pp. 791-805
    • Miyamoto, S.1    Teramoto, H.2    Coso, O.A.3
  • 65
    • 0027679403 scopus 로고
    • Integrin cytoplasmic domains: Mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
    • Sastry SK, Horwitz A. Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling. Curr Opin Cell Biol 1993;5:819-832
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 819-832
    • Sastry, S.K.1    Horwitz, A.2
  • 66
    • 0030484702 scopus 로고    scopus 로고
    • Role of integrins in angiogenesis
    • Brooks PC. Role of integrins in angiogenesis. Eur J Cancer 1996;14:2423-2429
    • (1996) Eur J Cancer , vol.14 , pp. 2423-2429
    • Brooks, P.C.1
  • 67
    • 0030117714 scopus 로고    scopus 로고
    • Cellular adhesion molecules: Newly identified mediators of angiogenesis
    • Polverini PJ. Cellular adhesion molecules: newly identified mediators of angiogenesis. Am J Pathol 1996;148:1023-1029
    • (1996) Am J Pathol , vol.148 , pp. 1023-1029
    • Polverini, P.J.1
  • 68
    • 0027008419 scopus 로고
    • Basic FGF and TGF-β differential modulate integrin expression of human microvascular endothelial cells
    • Enenstein J, Walesh NS, Kramer RH. Basic FGF and TGF-β differential modulate integrin expression of human microvascular endothelial cells. Exp Cell Res 1992;203:499-503
    • (1992) Exp Cell Res , vol.203 , pp. 499-503
    • Enenstein, J.1    Walesh, N.S.2    Kramer, R.H.3
  • 69
    • 0026683840 scopus 로고
    • Expression and modulation of vitronectin receptor on human dermal microvascular endothelial cells
    • Swerlick RA, Brown EJ, Xu Y, et al. Expression and modulation of vitronectin receptor on human dermal microvascular endothelial cells. J Invest Dermatol 1992;99:715-722
    • (1992) J Invest Dermatol , vol.99 , pp. 715-722
    • Swerlick, R.A.1    Brown, E.J.2    Xu, Y.3
  • 70
    • 0026586110 scopus 로고
    • Antibodies to β1-integrins cause alterations of aortic vascularization in vivo
    • Drake CJ, Davis LA, Little CD. Antibodies to β1-integrins cause alterations of aortic vascularization in vivo. Dev Dyn 1991;193:83-91
    • (1991) Dev Dyn , vol.193 , pp. 83-91
    • Drake, C.J.1    Davis, L.A.2    Little, C.D.3
  • 71
    • 0028981497 scopus 로고
    • 3, prevents maturation of blood vessels during embryonic neovascularization
    • 3, prevents maturation of blood vessels during embryonic neovascularization. J Cell Sci 1995;108:2655-2661
    • (1995) J Cell Sci , vol.108 , pp. 2655-2661
    • Drake, C.J.1    Cheresh, D.A.2    Little, C.D.3
  • 72
    • 0030809457 scopus 로고    scopus 로고
    • Targeted mutations in integrins and their ligands: Their implications for vascular biology
    • Hynes RO, Bader BL. Targeted mutations in integrins and their ligands: their implications for vascular biology. Thromb Haemost 1997;78:83-87
    • (1997) Thromb Haemost , vol.78 , pp. 83-87
    • Hynes, R.O.1    Bader, B.L.2
  • 73
    • 0030589587 scopus 로고    scopus 로고
    • Targeted mutations in cell adhesion genes: What have we learned from them?
    • Hynes RO. Targeted mutations in cell adhesion genes: what have we learned from them? Dev Biol 1996;180:40-412
    • (1996) Dev Biol , vol.180 , pp. 40-412
    • Hynes, R.O.1
  • 74
    • 0028143758 scopus 로고
    • Confocal microscope analysis of integrin expression on the microvascular and its sprouts in the neonatal foreskin
    • Erenstein J, Kramer RH. Confocal microscope analysis of integrin expression on the microvascular and its sprouts in the neonatal foreskin. J Invest Dermatol 1994;103:381-386
    • (1994) J Invest Dermatol , vol.103 , pp. 381-386
    • Erenstein, J.1    Kramer, R.H.2
  • 76
    • 0028670833 scopus 로고
    • 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994;79:1157-1164
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.P.2    Rosenfeld, M.3
  • 78
    • 0029925079 scopus 로고    scopus 로고
    • Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization
    • Hammes H-P, Brownlee M, Jonczyk A, et al. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Nature Med 1996;5:529-533
    • (1996) Nature Med , vol.5 , pp. 529-533
    • Hammes, H.-P.1    Brownlee, M.2    Jonczyk, A.3
  • 79
    • 0029843947 scopus 로고    scopus 로고
    • Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases
    • Friedlander M, Theesfeld CL, Sugita M, et al. Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases. Proc Natl Acad Sci USA 1996;93: 9764-9769
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9764-9769
    • Friedlander, M.1    Theesfeld, C.L.2    Sugita, M.3
  • 80
    • 0029001244 scopus 로고
    • Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
    • Sato TN, Tozawa Y, Deutsch U, et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995;376:70-74
    • (1995) Nature , vol.376 , pp. 70-74
    • Sato, T.N.1    Tozawa, Y.2    Deutsch, U.3
  • 81
    • 0027368264 scopus 로고
    • Tie-1 and Tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system
    • Sato TN, Qin Y, Kozak CA, Audus KL. Tie-1 and Tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system. Proc Natl Acad Sci USA 1993;90:9355-9358
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9355-9358
    • Sato, T.N.1    Qin, Y.2    Kozak, C.A.3    Audus, K.L.4
  • 82
    • 0027515802 scopus 로고
    • Expression of Tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage
    • Schnurch H, Risau W. Expression of Tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage. Development 1993;119:957-968
    • (1993) Development , vol.119 , pp. 957-968
    • Schnurch, H.1    Risau, W.2
  • 83
    • 0028006242 scopus 로고
    • The mouse tie receptor tyrosine kinase gene: Expression during embryonic angiogenesis
    • Korhonen J, Polvi A, Partanen J, and Alitalo K. The mouse tie receptor tyrosine kinase gene: expression during embryonic angiogenesis. Oncogene 1994;9:395-403
    • (1994) Oncogene , vol.9 , pp. 395-403
    • Korhonen, J.1    Polvi, A.2    Partanen, J.3    Alitalo, K.4
  • 84
    • 0030480322 scopus 로고    scopus 로고
    • Requisite role of Angiopoietin-1, a ligand for the TIE-2 receptor, during embryonic angiogenesis
    • Suri C, Jones PF, Patan S, et al. Requisite role of Angiopoietin-1, a ligand for the TIE-2 receptor, during embryonic angiogenesis. Cell 1996;87:1171-1180
    • (1996) Cell , vol.87 , pp. 1171-1180
    • Suri, C.1    Jones, P.F.2    Patan, S.3
  • 85
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie-2 that disrupts in vivo angiogenesis
    • Maisonpierre PC, Suri C, Jones PJ, et al. Angiopoietin-2, a natural antagonist for Tie-2 that disrupts in vivo angiogenesis. Science 1997;277:55-60
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1    Suri, C.2    Jones, P.J.3
  • 86
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997;277: 48-50
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1


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