메뉴 건너뛰기




Volumn 24, Issue 2 SPEC. ISS., 2006, Pages 141-151

Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model

Author keywords

Docetaxel; Gene therapy; Oligonucleotide; Prostate cancer; Telomerase; Telomerase inhibition

Indexed keywords

ANDROGEN; ANTISENSE OLIGODEOXYNUCLEOTIDE; DOCETAXEL; EOSIN; GRN 163; HEMATOXYLIN; ISIS 125628; ISIS 24691; OLIGONUCLEOTIDE; PROSTATE SPECIFIC ANTIGEN; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 33644762771     PISSN: 10781439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.urolonc.2005.11.003     Document Type: Conference Paper
Times cited : (13)

References (74)
  • 1
    • 0344622606 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • L. Hayfick, P.S. Moorhead The limited in vitro lifetime of human diploid cell strains Exp Cell Res 25 1961 585 621
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayfick, L.1    Moorhead, P.S.2
  • 2
    • 0015515155 scopus 로고
    • Origin of concatemeric T7 DNA
    • J.D. Watson Origin of concatemeric T7 DNA Nat New Biol 239 1972 197 201
    • (1972) Nat New Biol , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 3
    • 0015844590 scopus 로고
    • A theory of marginotomy: The incomplete copying of template margin in enzymatic synthesis of polynucleotides and the biological significance of the phenomenon
    • A.M. Olovnikov A theory of marginotomy The incomplete copying of template margin in enzymatic synthesis of polynucleotides and the biological significance of the phenomenon J Theor Biol 41 1973 181 190
    • (1973) J Theor Biol , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 4
    • 0034733606 scopus 로고    scopus 로고
    • Telomere shortening is proportional to the size of the G-rich telomeric 3′-overhang
    • K.E. Huffman, S.D. Levene, V.M. Tesmer Telomere shortening is proportional to the size of the G-rich telomeric 3′-overhang J Biol Chem 275 2000 19719 19722
    • (2000) J Biol Chem , vol.275 , pp. 19719-19722
    • Huffman, K.E.1    Levene, S.D.2    Tesmer, V.M.3
  • 5
    • 0025279931 scopus 로고
    • Telomeres shorten during aging of human fibroblasts
    • C.B. Harley, A.B. Futcher, C.W. Greider Telomeres shorten during aging of human fibroblasts Nature 345 1990 458 460
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 6
    • 0025143252 scopus 로고
    • Telomere reduction in human colorectal carcinoma and with aging
    • N.D. Hastie, M. Dempster, M.G. Dunlop Telomere reduction in human colorectal carcinoma and with aging Nature 346 1990 866 868
    • (1990) Nature , vol.346 , pp. 866-868
    • Hastie, N.D.1    Dempster, M.2    Dunlop, M.G.3
  • 8
    • 0013462065 scopus 로고
    • A highly conserved repetitive DNA sequence, (TTAGGG)n, present at telomeres of human chromosomes
    • R.K. Moyzis, J.D. Buckingham, L.S. Cram A highly conserved repetitive DNA sequence, (TTAGGG)n, present at telomeres of human chromosomes Proc Natl Acad Sci USA 85 1988 6622 6626
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6622-6626
    • Moyzis, R.K.1    Buckingham, J.D.2    Cram, L.S.3
  • 9
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • V.L. Makarov, Y. Hirose, J.P. Langmore Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening Cell 88 1997 657 666
    • (1997) Cell , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 10
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • B. Van Steensel, A. Smogorzewska, T. de Lange TRF2 protects human telomeres from end-to-end fusions Cell 92 1998 401 413
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 11
    • 0033553536 scopus 로고    scopus 로고
    • Mammalian telomeres end in a large duplex loop
    • J.D. Griffith, L. Comeau, S. Rosenfield Mammalian telomeres end in a large duplex loop Cell 97 1999 503 514
    • (1999) Cell , vol.97 , pp. 503-514
    • Griffith, J.D.1    Comeau, L.2    Rosenfield, S.3
  • 13
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • C.J. Sherr, F. McCormick The RB and p53 pathways in cancer Cancer Cell 2 2002 103 112
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 14
    • 0037102234 scopus 로고    scopus 로고
    • Different telomere damage signaling pathways in human and mouse cells
    • A. Smogorzewska, T. de Lange Different telomere damage signaling pathways in human and mouse cells EMBO J 21 2002 4338 4348
    • (2002) EMBO J , vol.21 , pp. 4338-4348
    • Smogorzewska, A.1    De Lange, T.2
  • 15
    • 0036782884 scopus 로고    scopus 로고
    • Telomerase: A target for cancer therapeutics
    • J.W. Shay, W.E. Wright Telomerase A target for cancer therapeutics Cancer Cell 2 2002 257 265
    • (2002) Cancer Cell , vol.2 , pp. 257-265
    • Shay, J.W.1    Wright, W.E.2
  • 16
    • 0023034140 scopus 로고
    • Variability at the telomeres of the human X/Y pseudoautosomal region
    • H.J. Cooke, B.A. Smith Variability at the telomeres of the human X/Y pseudoautosomal region Cold Spring Harb Symp Quant Biol 51 1986 213 219
    • (1986) Cold Spring Harb Symp Quant Biol , vol.51 , pp. 213-219
    • Cooke, H.J.1    Smith, B.A.2
  • 17
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • C.B. Harley Telomere loss Mitotic clock or genetic time bomb? Mutat Res 256 1991 271 282
    • (1991) Mutat Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 18
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • N.W. Kim, M.A. Pietyszek, K.R. Prowse Specific association of human telomerase activity with immortal cells and cancer Science 266 1994 2011 2020
    • (1994) Science , vol.266 , pp. 2011-2020
    • Kim, N.W.1    Pietyszek, M.A.2    Prowse, K.R.3
  • 19
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • J.W. Shay, S. Bacchetti A survey of telomerase activity in human cancer Eur J Cancer 5 1997 787 791
    • (1997) Eur J Cancer , vol.5 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 20
    • 0029096515 scopus 로고
    • The RNA component of human telomerase
    • J. Feng, W.D. Funk, S.-S. Wang The RNA component of human telomerase Science 269 1995 1236 1241
    • (1995) Science , vol.269 , pp. 1236-1241
    • Feng, J.1    Funk, W.D.2    Wang, S.-S.3
  • 21
    • 0030819894 scopus 로고    scopus 로고
    • Telomerase catalytic subunit homologs from fission yeast and human
    • T.M. Nakamura, G.B. Morin, K.B. Chapman Telomerase catalytic subunit homologs from fission yeast and human Science 277 1997 955 959
    • (1997) Science , vol.277 , pp. 955-959
    • Nakamura, T.M.1    Morin, G.B.2    Chapman, K.B.3
  • 22
    • 0030745448 scopus 로고    scopus 로고
    • HEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
    • M. Meyerson, C.M. Counter, E.N. Eaton hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization Cell 90 1997 785 795
    • (1997) Cell , vol.90 , pp. 785-795
    • Meyerson, M.1    Counter, C.M.2    Eaton, E.N.3
  • 23
    • 0030668722 scopus 로고    scopus 로고
    • Human telomerase contains evolutionarily conserved catalytic and structural subunits
    • L. Harrington, T. McPhail, V. Mar Human telomerase contains evolutionarily conserved catalytic and structural subunits Genes Dev 11 1997 3109 3115
    • (1997) Genes Dev , vol.11 , pp. 3109-3115
    • Harrington, L.1    McPhail, T.2    Mar, V.3
  • 24
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • A.G. Bodnar, M. Ouellette, M. Frolkis Extension of life-span by introduction of telomerase into normal human cells Science 279 1998 349 352
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1    Ouellette, M.2    Frolkis, M.3
  • 25
    • 0032924343 scopus 로고    scopus 로고
    • Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
    • C.P. Morales, S.E. Holt, M. Ouellette Absence of cancer-associated changes in human fibroblasts immortalized with telomerase Nat Genet 21 1999 115 118
    • (1999) Nat Genet , vol.21 , pp. 115-118
    • Morales, C.P.1    Holt, S.E.2    Ouellette, M.3
  • 26
    • 0037148328 scopus 로고    scopus 로고
    • Telomerase is not an oncogene
    • C.B. Harley Telomerase is not an oncogene Oncogene 21 2002 494 502
    • (2002) Oncogene , vol.21 , pp. 494-502
    • Harley, C.B.1
  • 27
    • 0033614998 scopus 로고    scopus 로고
    • Creation of human tumour cells with defined genetic elements
    • W.C. Hahn, C.M. Counter, A.S. Lundberg Creation of human tumour cells with defined genetic elements Nature 400 1999 464 468
    • (1999) Nature , vol.400 , pp. 464-468
    • Hahn, W.C.1    Counter, C.M.2    Lundberg, A.S.3
  • 28
    • 0033455559 scopus 로고    scopus 로고
    • Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
    • B.S. Herbert, A.E. Pitts, S.I. Baker Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death Proc Natl Acad Sci USA 96 1999 14276 14281
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14276-14281
    • Herbert, B.S.1    Pitts, A.E.2    Baker, S.I.3
  • 29
    • 0033568462 scopus 로고    scopus 로고
    • Telomere shortening and apoptosis in telomerase-inhibited human tumour cells
    • X.L. Zhang, V. Mar, W. Zhou Telomere shortening and apoptosis in telomerase-inhibited human tumour cells Genes Dev 13 1999 2388 2399
    • (1999) Genes Dev , vol.13 , pp. 2388-2399
    • Zhang, X.L.1    Mar, V.2    Zhou, W.3
  • 30
    • 0027956728 scopus 로고
    • Telomerase activity in vivo in human malignant hematopoietic cells
    • P. Nilsson, C. Mehle, K. Remes Telomerase activity in vivo in human malignant hematopoietic cells Oncogene 9 1994 3043 3048
    • (1994) Oncogene , vol.9 , pp. 3043-3048
    • Nilsson, P.1    Mehle, C.2    Remes, K.3
  • 32
    • 0028827339 scopus 로고
    • Telomerase activity in human brain tumors
    • L.A. Langford, M.A. Piatyszek, R. Xu Telomerase activity in human brain tumors Lancet 346 1995 1267 1268
    • (1995) Lancet , vol.346 , pp. 1267-1268
    • Langford, L.A.1    Piatyszek, M.A.2    Xu, R.3
  • 33
    • 0028201293 scopus 로고
    • Activation of telomerase in human tumor
    • T. de Lange Activation of telomerase in human tumor Proc Natl Acad Sci USA 91 1994 2882 2885
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2882-2885
    • De Lange, T.1
  • 34
    • 0031021828 scopus 로고    scopus 로고
    • Telomerase activity in primary prostate cancer
    • Y. Lin, H. Uemura, K. Fujinami Telomerase activity in primary prostate cancer J Urol 157 1997 1161 1165
    • (1997) J Urol , vol.157 , pp. 1161-1165
    • Lin, Y.1    Uemura, H.2    Fujinami, K.3
  • 35
    • 0031836027 scopus 로고    scopus 로고
    • Detection of telomerase activity in prostate needle-biopsy samples
    • Y. Lin, H. Uemura, K. Fujinami Detection of telomerase activity in prostate needle-biopsy samples Prostate 36 1998 121 128
    • (1998) Prostate , vol.36 , pp. 121-128
    • Lin, Y.1    Uemura, H.2    Fujinami, K.3
  • 36
    • 0032519561 scopus 로고    scopus 로고
    • Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium
    • W. Zhang, L.R. Kapusta, J.M. Slingerland Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium Cancer Res 58 1998 619 622
    • (1998) Cancer Res , vol.58 , pp. 619-622
    • Zhang, W.1    Kapusta, L.R.2    Slingerland, J.M.3
  • 37
    • 0031443668 scopus 로고    scopus 로고
    • Telomerase activity in human benign prostate tissue and prostatic adenocarcinomas
    • B.V. Kallakury, V.S. Bhaskar, T.P. Brien Telomerase activity in human benign prostate tissue and prostatic adenocarcinomas Diagn Mol Pathol 6 1997 192 198
    • (1997) Diagn Mol Pathol , vol.6 , pp. 192-198
    • Kallakury, B.V.1    Bhaskar, V.S.2    Brien, T.P.3
  • 38
    • 0030838267 scopus 로고    scopus 로고
    • Detection of telomerase activity in prostate cancer by needle biopsy
    • C. Takahashi, I. Miyagawa, S. Kumano Detection of telomerase activity in prostate cancer by needle biopsy Eur Urol 32 1997 494 498
    • (1997) Eur Urol , vol.32 , pp. 494-498
    • Takahashi, C.1    Miyagawa, I.2    Kumano, S.3
  • 39
    • 0030061426 scopus 로고    scopus 로고
    • Telomerase activity: A prevalent marker of malignant human prostate tissue
    • H.J. Sommerfeld, A.K. Meeker, M.A. Piatyszek Telomerase activity A prevalent marker of malignant human prostate tissue Cancer Res 56 1996 218 222
    • (1996) Cancer Res , vol.56 , pp. 218-222
    • Sommerfeld, H.J.1    Meeker, A.K.2    Piatyszek, M.A.3
  • 40
    • 0032829439 scopus 로고    scopus 로고
    • Focal intratumoral heterogeneity for telomerase activity in human prostate cancer
    • B. Wullich, V. Rohde, B. Oehlenschlager Focal intratumoral heterogeneity for telomerase activity in human prostate cancer J Urol 161 1999 1997 2001
    • (1999) J Urol , vol.161 , pp. 1997-2001
    • Wullich, B.1    Rohde, V.2    Oehlenschlager, B.3
  • 41
    • 0032322451 scopus 로고    scopus 로고
    • Telomerase activity, telomere length and DNA ploidy in prostatic intraepithelial neoplasia (PIN)
    • K. Koenenman, C.X. Pan, J.K. Jin Telomerase activity, telomere length and DNA ploidy in prostatic intraepithelial neoplasia (PIN) J Urol 160 1998 1533 1539
    • (1998) J Urol , vol.160 , pp. 1533-1539
    • Koenenman, K.1    Pan, C.X.2    Jin, J.K.3
  • 42
    • 4243937106 scopus 로고    scopus 로고
    • A highly selective telomerase inhibitor limiting human cancer cell proliferation
    • K. Damm, U. Hemmann, P. Garin-Chesa A highly selective telomerase inhibitor limiting human cancer cell proliferation EMBO J 20 2001 6958 6968
    • (2001) EMBO J , vol.20 , pp. 6958-6968
    • Damm, K.1    Hemmann, U.2    Garin-Chesa, P.3
  • 43
    • 12344288452 scopus 로고    scopus 로고
    • Mechanism-based combination telomerase inhibition therapy
    • J.W. Shay, W.E. Wright Mechanism-based combination telomerase inhibition therapy Cancer Cell 7 2005 1 2
    • (2005) Cancer Cell , vol.7 , pp. 1-2
    • Shay, J.W.1    Wright, W.E.2
  • 44
    • 0036362266 scopus 로고    scopus 로고
    • Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
    • N.R. Forsyth, W.E. Wright, J.W. Shay Telomerase and differentiation in multicellular organisms Turn it off, turn it on, and turn it off again Differentiation 69 2002 188 197
    • (2002) Differentiation , vol.69 , pp. 188-197
    • Forsyth, N.R.1    Wright, W.E.2    Shay, J.W.3
  • 45
    • 0035874515 scopus 로고    scopus 로고
    • The relative quiescence of hematopoietic stem cells in nonhuman primates
    • N. Mahmud, S.M. Devine, K.P. Weller The relative quiescence of hematopoietic stem cells in nonhuman primates Blood 97 2001 3061 3068
    • (2001) Blood , vol.97 , pp. 3061-3068
    • Mahmud, N.1    Devine, S.M.2    Weller, K.P.3
  • 46
    • 0034933876 scopus 로고    scopus 로고
    • A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
    • M.M. Kim, M.A. Rivera, I.L. Botchkina A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation Proc Natl Acad Sci USA 98 2001 7982 7987
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7982-7987
    • Kim, M.M.1    Rivera, M.A.2    Botchkina, I.L.3
  • 47
    • 0034904662 scopus 로고    scopus 로고
    • FADD gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter to restrict induction of apoptosis to tumors in vitro and in vivo
    • S. Koga, S. Hirohata, Y. Kondo FADD gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter to restrict induction of apoptosis to tumors in vitro and in vivo Anticancer Res 21 2001 1937 1943
    • (2001) Anticancer Res , vol.21 , pp. 1937-1943
    • Koga, S.1    Hirohata, S.2    Kondo, Y.3
  • 48
    • 0036166825 scopus 로고    scopus 로고
    • HTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity
    • J. Gu, M. Andreff, J.A. Roth hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity Gene Ther 9 2002 30 37
    • (2002) Gene Ther , vol.9 , pp. 30-37
    • Gu, J.1    Andreff, M.2    Roth, J.A.3
  • 49
    • 0037148344 scopus 로고    scopus 로고
    • Telomerase as a universal tumor-associated antigen for cancer immunotherapy
    • R.H. Vonderheide Telomerase as a universal tumor-associated antigen for cancer immunotherapy Oncogene 21 2002 674 679
    • (2002) Oncogene , vol.21 , pp. 674-679
    • Vonderheide, R.H.1
  • 50
    • 0037442701 scopus 로고    scopus 로고
    • Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo
    • I. Naasani, F. Oh-Hashi, T. Oh-Hara Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo Cancer Res 63 2003 824 830
    • (2003) Cancer Res , vol.63 , pp. 824-830
    • Naasani, I.1    Oh-Hashi, F.2    Oh-Hara, T.3
  • 51
    • 0030786928 scopus 로고    scopus 로고
    • Inhibition of human telomerase by a G-quadruplex-interactive compound
    • D. Sun, B. Thompson, B.E. Cathers Inhibition of human telomerase by a G-quadruplex-interactive compound J Med Chem 40 1997 2113 2116
    • (1997) J Med Chem , vol.40 , pp. 2113-2116
    • Sun, D.1    Thompson, B.2    Cathers, B.E.3
  • 52
    • 0029655485 scopus 로고    scopus 로고
    • Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
    • C. Strahl, E.H. Blackburn Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines Mol Cell Biol 16 1996 53 65
    • (1996) Mol Cell Biol , vol.16 , pp. 53-65
    • Strahl, C.1    Blackburn, E.H.2
  • 53
    • 0032403264 scopus 로고    scopus 로고
    • Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells
    • Y. Yokoyama, T. Takahashi, A. Shinohara Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells Cancer Res 58 1998 5406 5410
    • (1998) Cancer Res , vol.58 , pp. 5406-5410
    • Yokoyama, Y.1    Takahashi, T.2    Shinohara, A.3
  • 54
    • 0037148329 scopus 로고    scopus 로고
    • Telomerase inhibition, oligonucleotides, and clinical trials
    • D.R. Corey Telomerase inhibition, oligonucleotides, and clinical trials Oncogene 21 2002 631 637
    • (2002) Oncogene , vol.21 , pp. 631-637
    • Corey, D.R.1
  • 55
    • 0037148567 scopus 로고    scopus 로고
    • Oligonucleotide N3′-P5′ phosphoramidates as efficient telomerase inhibitors
    • B.S. Herbert, K. Pongracz, J.W. Shay Oligonucleotide N3′-P5′ phosphoramidates as efficient telomerase inhibitors Oncogene 21 2002 638 642
    • (2002) Oncogene , vol.21 , pp. 638-642
    • Herbert, B.S.1    Pongracz, K.2    Shay, J.W.3
  • 56
    • 0032724911 scopus 로고    scopus 로고
    • Novel mechanisms for antisense-mediated regulation of gene expression
    • B.F. Baker, B.P. Monia Novel mechanisms for antisense-mediated regulation of gene expression Biochim Biophys Acta 1489 1999 3 18
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 3-18
    • Baker, B.F.1    Monia, B.P.2
  • 57
    • 0036846993 scopus 로고    scopus 로고
    • Antisense therapy for cancer: The time of truth
    • B. Jansen, U. Zangemeister-Wittke Antisense therapy for cancer the time of truth Lancet Oncol 3 2002 672 682
    • (2002) Lancet Oncol , vol.3 , pp. 672-682
    • Jansen, B.1    Zangemeister-Wittke, U.2
  • 58
    • 0033792733 scopus 로고    scopus 로고
    • Telomerase: An unusual target for cytotoxic agents
    • D.R. Corey Telomerase An unusual target for cytotoxic agents Chem Res Toxicol 13 2000 957 960
    • (2000) Chem Res Toxicol , vol.13 , pp. 957-960
    • Corey, D.R.1
  • 59
    • 0034780950 scopus 로고    scopus 로고
    • Drug properties of second-generation antisense oligonucleotides: How do they measure up to their predecessors?
    • R.S. Geary, R.Z. Yu, A.A. Levin Drug properties of second-generation antisense oligonucleotides How do they measure up to their predecessors? Curr Opin Investig Drugs 2 2001 1444 1449
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 1444-1449
    • Geary, R.S.1    Yu, R.Z.2    Levin, A.A.3
  • 60
    • 0141842659 scopus 로고    scopus 로고
    • Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells
    • Z. Chen, K. Koeneman, D.R. Corey Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells Cancer Res 63 2003 5917 5925
    • (2003) Cancer Res , vol.63 , pp. 5917-5925
    • Chen, Z.1    Koeneman, K.2    Corey, D.R.3
  • 61
    • 0023651145 scopus 로고
    • Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides
    • H. Inoue, Y. Hayase, A. Imura Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides Nucleic Acids Res 15 1987 6131 6148
    • (1987) Nucleic Acids Res , vol.15 , pp. 6131-6148
    • Inoue, H.1    Hayase, Y.2    Imura, A.3
  • 62
    • 0027168725 scopus 로고
    • Evaluation of 2′ modified oligonucleotides containing deoxy gaps as antisense inhibitors of gene expression
    • B.P. Monia, E.A. Lesnik, C. Gonzalez Evaluation of 2′ modified oligonucleotides containing deoxy gaps as antisense inhibitors of gene expression J Biol Chem 268 1993 14514 14522
    • (1993) J Biol Chem , vol.268 , pp. 14514-14522
    • Monia, B.P.1    Lesnik, E.A.2    Gonzalez, C.3
  • 63
    • 0033555551 scopus 로고    scopus 로고
    • Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression
    • R.A. McKay, L.J. Miraglia, L.L. Cummins Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression J Biol Chem 274 1999 1715 1722
    • (1999) J Biol Chem , vol.274 , pp. 1715-1722
    • McKay, R.A.1    Miraglia, L.J.2    Cummins, L.L.3
  • 64
    • 0031010177 scopus 로고    scopus 로고
    • 2′-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells
    • B.F. Baker, S.S. Lot, T.P. Condon 2′-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells J Biol Chem 272 1997 11994 12000
    • (1997) J Biol Chem , vol.272 , pp. 11994-12000
    • Baker, B.F.1    Lot, S.S.2    Condon, T.P.3
  • 65
    • 0033965192 scopus 로고    scopus 로고
    • Chemically modified oligonucleotides exhibit decreased immune stimulation in mice
    • S.P. Henry, K. Stecker, D. Brooks Chemically modified oligonucleotides exhibit decreased immune stimulation in mice J Pharmacol Exp Ther 292 2000 468 479
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 468-479
    • Henry, S.P.1    Stecker, K.2    Brooks, D.3
  • 66
    • 0031005761 scopus 로고    scopus 로고
    • Phase II trial of docetaxel in-patients with advanced or metastatic transitional-cell carcinoma
    • J.A. McCaffrey, S. Hilton, M. Mazumdar Phase II trial of docetaxel in-patients with advanced or metastatic transitional-cell carcinoma J Clin Oncol 15 1997 1853 1857
    • (1997) J Clin Oncol , vol.15 , pp. 1853-1857
    • McCaffrey, J.A.1    Hilton, S.2    Mazumdar, M.3
  • 67
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • D.P. Petrylak, C.M. Tangen, M.H. Hussain Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer N Engl J Med 351 2004 1513 1520
    • (2004) N Engl J Med , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.3
  • 68
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • I.F. Tannock, R. de Wit, W.R. Berry Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer N Engl J Med 351 2004 1502 1512
    • (2004) N Engl J Med , vol.351 , pp. 1502-1512
    • Tannock, I.F.1    De Wit, R.2    Berry, W.R.3
  • 69
    • 0242607821 scopus 로고    scopus 로고
    • New targets for therapy in prostate cancer: Modulation of stromal-epithelial interactions
    • L.W. Chung, C.L. Hsieh, A. Law New targets for therapy in prostate cancer Modulation of stromal-epithelial interactions Urology 62 2003 44 54
    • (2003) Urology , vol.62 , pp. 44-54
    • Chung, L.W.1    Hsieh, C.L.2    Law, A.3
  • 70
    • 0024383451 scopus 로고
    • Assessment of in vitro lymphokine activated killer (LAK) cell activity against renal cancer cell lines and its suppression by serum factor using crystal violet assay
    • H. Kanamaru, O. Yoshida Assessment of in vitro lymphokine activated killer (LAK) cell activity against renal cancer cell lines and its suppression by serum factor using crystal violet assay Urol Res 17 1989 259 264
    • (1989) Urol Res , vol.17 , pp. 259-264
    • Kanamaru, H.1    Yoshida, O.2
  • 71
    • 0034616215 scopus 로고    scopus 로고
    • Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
    • M.M. Ouellette, M. Liao, B. Herbert Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase J Biol Chem 275 2000 10072 10076
    • (2000) J Biol Chem , vol.275 , pp. 10072-10076
    • Ouellette, M.M.1    Liao, M.2    Herbert, B.3
  • 72
    • 0036136852 scopus 로고    scopus 로고
    • Enhanced transgene expression in androgen independent prostate cancer gene therapy by taxane chemotherapeutic agents
    • Y. Li, T. Okegawa, D.P. Lombardi Enhanced transgene expression in androgen independent prostate cancer gene therapy by taxane chemotherapeutic agents J Urol 167 2002 339 346
    • (2002) J Urol , vol.167 , pp. 339-346
    • Li, Y.1    Okegawa, T.2    Lombardi, D.P.3
  • 73
    • 0037442425 scopus 로고    scopus 로고
    • Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells
    • X. Zhang, A.S. Multani, J.H. Zhou Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells Cancer Res 63 2003 760 765
    • (2003) Cancer Res , vol.63 , pp. 760-765
    • Zhang, X.1    Multani, A.S.2    Zhou, J.H.3
  • 74
    • 21244502260 scopus 로고    scopus 로고
    • Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA
    • S. Li, J. Crothers, C.M. Haqq Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA J Biol Chem 280 2005 23709 23717
    • (2005) J Biol Chem , vol.280 , pp. 23709-23717
    • Li, S.1    Crothers, J.2    Haqq, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.