Telomerase activity, telomere length, and DNA ploidy in prostatic intraepithelial neoplasia (PIN)

Journal of Urology

Volumn 160, Issue 4, 1998, Pages 1533-1539

  Koeneman, Kenneth S ^a   Pan, Chong Xian ^b   Jin, Jia Kuan ^b   Pyle III, Joseph M ^b   Flanigan, Robert C ^b   Shankey, T Vincent ^b   Diaz, Manuel O ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b NONE

Author keywords

DNA ploidy; Prostatic intraepithelial neoplasia; Telomerase; Telomere length

Indexed keywords

DNA; TELOMERASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DNA CONTENT; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MALE; PLOIDY; POLYMERASE CHAIN REACTION; PRECANCER; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE CARCINOMA; RESTRICTION FRAGMENT; SOUTHERN BLOTTING; TELOMERE;

EID: 0032322451     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)62608-9     Document Type: Article

References (30)

1. Bostwick, D. G., Pacelli, A. and Lopez-Beltram, A.: Molecular biology of prostatic intraepithelial neoplasia. Prostate, 29:117, 1996.
2. Haggman, M. J., Macoska, J. A., Wojno, K. J. and Oesterling, J. E.: The relationship between prostatic intraepithelial neoplasia and prostate cancer: critical issues. J. Urol., 158: 12, 1997.
3. Greider, C. W. and Blackburn, E. H.: The terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell, 51: 887, 1987.
4. Ezzell, C.: The telomerase - cancer connection: will exceptions make a new rule? J. NIH Res., 7: 41, 1995.
5. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L. and Shay, J. W., Specific association of human telomerase activity with immortalized cells and cancer. Science, 266: 2011, 1994.
6. Karp, J. E., Chiarodo, A., Brawley, O. and Kelloff, G. J.: Prostate cancer prevention: investigational approaches and opportunities. Cancer Res., 56: 5547, 1996.
7. Lin, Y., Uemura, H., Fujinami, K., Hosaka, M., Hurada, M. and Kubota, Y.: Telomerase activity in primary prostate cancer. J. Urol., 157: 1161, 1997.
8. Sommerfield, H., Meeker, A. K., Piatyszek, M. A., Bova, G. S., Shag, J. W. and Coffey, D. S.: Telomerase activity: a prevalent marker of malignant human prostate tissue. Cancer Res., 56: 218, 1996.
9. Tribukait, B.: DNA flow cytometry in carcinoma of the prostate for diagnosis, prognosis and study of tumor biology. Acta Oncol., 30: 187, 1991.
10. Shankey, T. V., Jin, J. K., Dougherty, S., Flanigan, R. C., Grahamn, S. and Pyle, J. M.: DNA ploidy and proliferation heterogeneity in human prostatic cancers. Cytometry, 21: 30, 1995.
11. Shankey, T. V., Kallioniemi, O-P., Koslowski, J. M., Lieber, M. M, Mayall, B. H., Miller, G. and Smith, G. J.: Consensus review of the clinical utility of DNA content cytometry in prostate cancer. Cytometry, 14: 497, 1993.
12. Petein, M., Michael, P. and van Velthoven, R.: Morphonuclear relationship between prostatic intraepithelial neoplasia and cancers as assessed by digital cell image analysis. Am. J. Clin. Pathol., 96: 628, 1991.
13. Weinberg, D. S. and Weidner, N.: Concordance of DNA content between prostatic intraepithelial neoplasia and concomitant invasive carcinoma. Arch. Pathol. Lab. Med., 117: 1132, 1993.
14. Bobbo, M., Dytch, H. E., Alenghat, E., Bartels, P. H. and Weid, G. L.: DNA ploidy profiles as prognostic indicators in CIN lesions. Am. J. Clin. Pathol., 92: 261, 1989.
15. Davidson, D., Bostwick, D. G., Qian, J., Wollan, P. C., Oesterling, J. E., Rudders, R. A., Siroky, M. and Stilmant, M.: Prostatic intrepithelial neoplasia is a risk factor for adenocarcinoma: predictive accuracy in needle biopsies. J. Urol., 154: 1295, 1995.
16. Bostwick, D. G., Amin, M. B., Dundore, P., Marsh, W. and Schultz, D. S.: Architectural patterns of high-grade prostatic intraepithelial neoplasia. Hum. Pathol., 24: 298, 1993.
17. Nagle, R. B., Brawer, M. K., Kittelson, J. and Clark, V.: Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma. Am. J. Pathol., 138: 119, 1991.
18. Zhuang, Z., Bertheau, P., Emmert - Buck, M. R., Liotta, L. A., Guarra, J., Linehan, W. M. and Lubensky, I. A.: A microdissection technique for archival DNA analysis of specific cell populations in lesions< 1 mm in size. Am. J. Pathol., 146: 620, 1995.
19. Wright, W. E., Shay, J. W. and Piatyszek, M. A.: Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity. Nucleic Acids Res., 23: 3794, 1995.
20. Piatyszek, M. A., Kim, N. W., Wienrich, S. C., Hiyam, K., Wright, W. E. and Shay, J. W.: Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci., 17: 1, 1995.
21. Hiyama, E., Yokoyama, T., Tatsumoto, N., Hiyam, K., Inamura, Y., Murakami, Y., Kodama, T., Piatyszek, M. A., Shay, J. W. and Matsura, Y., Telomerase activity in gastric cancer. Cancer Res., 55: 3258, 1995.
22. Dong, J., Isaacs, W. B. and Isaacs, J. T., Molecular advances in prostate cancers. Curr. Opin. Oncol., 9: 101, 1997.
23. Sakr, W. A., Haas, G. P., Cassin, B. F., Pontes, J. E. and Crissman, J. D.: The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients. J. Urol., 150: 379, 1993.
24. Shay, J. W. and Bacchett, S.: A survey of telomerase activity in human cancer. Eur. J. Cancer, 33: 787, 1997.
25. Engelhardt, M., Albanell, J., Drullinsky, P., Han, W., Guillem, J., Scher, H. I., Reuter, V. and Moore, M.: Relative contribution of normal and neoplastic cells determines telomerase activity, and telomere length in primary cancers of the prostate, colon and sarcoma. Clin. Cancer Res., 3: 1849, 1997.
26. Hiyama, E., Gollahon, L., Kataoka, T., Kuroi, K., Yokoyama, T., Gazdar, A. F., Hiyama, K., Piatyszek, M. A. and Shay, J. W.: Telomerase activity in human breast tumors. J. Natl. Cancer Inst., 88: 116, 1996.
27. Lin, Y., Miyamato, H., Fujinami, K., Uemura, H., Hosaka, M., Iwasaki, Y. and Kubota, Y.: Telomerase activity in human bladder cancer. Clin. Cancer Res., 2: 929, 1996.
28. Counter C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B. and Bachetti, S.: Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J., 11: 1929, 1992.
29. Blasco, M. A., Lee, H. W., Handie, M. P., Samper, J., Lansdorp, P. M., DePinho, R. A. and Greider, C. W.: Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell, 91: 25, 1997.
30. Kim, N. M.: Clinical implications of telomerase in cancer. Eur. J. Cancer, 33: 781, 1997.