-
1
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, Gaudet D, Hudson TJ, Daly M, Groop L, and Lander ES. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
Tuomi, T.11
Gaudet, D.12
Hudson, T.J.13
Daly, M.14
Groop, L.15
Lander, E.S.16
-
2
-
-
0002955624
-
Mechanisms of insulin secretion
-
edited by Ashcroft F and Ashcroft S. Oxford, UK: Oxford Univ. Press
-
Ashcroft E and Ashcroft S. Mechanisms of insulin secretion. In: Insulin: Molecular Biology to Pathology, edited by Ashcroft F and Ashcroft S. Oxford, UK: Oxford Univ. Press, 1992, p. 97-150.
-
(1992)
Insulin: Molecular Biology to Pathology
, pp. 97-150
-
-
Ashcroft, E.1
Ashcroft, S.2
-
3
-
-
0033213637
-
PPAR gamma is required for placental, cardiac, and adipose tissue development
-
Barak YNM, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, and Evans RM. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell 4: 585-595, 1999.
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.N.M.1
Ong, E.S.2
Jones, Y.Z.3
Ruiz-Lozano, P.4
Chien, K.R.5
Koder, A.6
Evans, R.M.7
-
4
-
-
0033135836
-
Mitochondrial 16189 variant, thinness at birth, and type-2 diabetes. ALSPAC study team. Avon Longitudinal Study of Pregnancy and Childhood
-
Casteels K, Ong K, Phillips D, Bendall H, Pembrey M, The study team ALSPAC, Poulton J, and Dunger D. Mitochondrial 16189 variant, thinness at birth, and type-2 diabetes. ALSPAC study team. Avon Longitudinal Study of Pregnancy and Childhood. Lancet 353: 1499-1500, 1999.
-
(1999)
Lancet
, vol.353
, pp. 1499-1500
-
-
Casteels, K.1
Ong, K.2
Phillips, D.3
Bendall, H.4
Pembrey, M.5
Poulton, J.6
Dunger, D.7
-
6
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans RM, Barish GD, and Wang YX. PPARs and the complex journey to obesity. Nat Med 10: 355-361, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
7
-
-
0033997281
-
Fetal growth and the physiological control of glucose tolerance in adults: A minimal model analysis
-
Flanagan DE, Moore VM, Godsland IF, Cockington RA, Robinson JS, and Phillips DI. Fetal growth and the physiological control of glucose tolerance in adults: a minimal model analysis. Am J Physiol Endocrinol Metab 278: E700-E706, 2000.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.278
-
-
Flanagan, D.E.1
Moore, V.M.2
Godsland, I.F.3
Cockington, R.A.4
Robinson, J.S.5
Phillips, D.I.6
-
8
-
-
0030020542
-
Maternal nutrition in early and late pregnancy in relation to placental and fetal growth
-
Godfrey K, Robinson S, Barker DJ, Osmond C, and Cox V. Maternal nutrition in early and late pregnancy in relation to placental and fetal growth. BMJ 312: 410-414, 1996.
-
(1996)
BMJ
, vol.312
, pp. 410-414
-
-
Godfrey, K.1
Robinson, S.2
Barker, D.J.3
Osmond, C.4
Cox, V.5
-
9
-
-
0025743129
-
The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight
-
Godfrey KM, Redman CW, Barker DJ, and Osmond C. The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight. Br J Obstet Gynaecol 98: 886-891, 1991.
-
(1991)
Br J Obstet Gynaecol
, vol.98
, pp. 886-891
-
-
Godfrey, K.M.1
Redman, C.W.2
Barker, D.J.3
Osmond, C.4
-
10
-
-
0031859976
-
Mutations in the glucokinase gene of the fetus result in reduced birth weight
-
Hattersley AT, Beards F, Ballantyne E, Appleton M, Harvey R, and Ellard S. Mutations in the glucokinase gene of the fetus result in reduced birth weight. Nat Genet 19: 268-270, 1998.
-
(1998)
Nat Genet
, vol.19
, pp. 268-270
-
-
Hattersley, A.T.1
Beards, F.2
Ballantyne, E.3
Appleton, M.4
Harvey, R.5
Ellard, S.6
-
11
-
-
10844226552
-
No evidence of an association between the mtDNA 16184-93 polyC tract and late onset dementia
-
Keers SM, Gibson AM, Turnbull DM, and Chinnery PF. No evidence of an association between the mtDNA 16184-93 polyC tract and late onset dementia. J Med Genet 41: 957-958, 2004.
-
(2004)
J Med Genet
, vol.41
, pp. 957-958
-
-
Keers, S.M.1
Gibson, A.M.2
Turnbull, D.M.3
Chinnery, P.F.4
-
12
-
-
2442609784
-
Recombination of human mitochondrial DNA
-
Kraytsberg Y, Schwartz M, Brown TA, Ebralidse K, Kunz WS, Clayton DA, Vissing J, and Khrapko K. Recombination of human mitochondrial DNA. Science 304: 981, 2004.
-
(2004)
Science
, vol.304
, pp. 981
-
-
Kraytsberg, Y.1
Schwartz, M.2
Brown, T.A.3
Ebralidse, K.4
Kunz, W.S.5
Clayton, D.A.6
Vissing, J.7
Khrapko, K.8
-
13
-
-
0029848022
-
Placental ratio and intrauterine growth retardation
-
Lao TT and Wong WM. Placental ratio and intrauterine growth retardation. Br J Obstet Gynaecol 103: 924-926, 1996.
-
(1996)
Br J Obstet Gynaecol
, vol.103
, pp. 924-926
-
-
Lao, T.T.1
Wong, W.M.2
-
14
-
-
0038795607
-
Mitochondrial biogenesis: Which part of "NO" do we understand?
-
Leary SC and Shoubridge EA. Mitochondrial biogenesis: which part of "NO" do we understand? Bioessays 25: 538-541, 2003.
-
(2003)
Bioessays
, vol.25
, pp. 538-541
-
-
Leary, S.C.1
Shoubridge, E.A.2
-
15
-
-
0037377395
-
Placental weight and its ratio to birthweight in a Ukrainian city
-
Little RE, Zadorozhnaja TD, Hulchiy OP, Mendel NA, Shkyryak-Nyzhnyk ZA, Chyslovska N, and Gladen BC. Placental weight and its ratio to birthweight in a Ukrainian city. Early Hum Dev 71: 117-127, 2003.
-
(2003)
Early Hum Dev
, vol.71
, pp. 117-127
-
-
Little, R.E.1
Zadorozhnaja, T.D.2
Hulchiy, O.P.3
Mendel, N.A.4
Shkyryak-Nyzhnyk, Z.A.5
Chyslovska, N.6
Gladen, B.C.7
-
16
-
-
0142209179
-
Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: A meta-analysis
-
Masud S and Ye S. Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis. J Med Genet 40: 773-780, 2003.
-
(2003)
J Med Genet
, vol.40
, pp. 773-780
-
-
Masud, S.1
Ye, S.2
-
17
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, and Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
18
-
-
0034119138
-
The perils of portliness: Causes and consequences of visceral adiposity
-
Montague CT and O'Rahilly S. The perils of portliness: causes and consequences of visceral adiposity. Diabetes 49: 883-888, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 883-888
-
-
Montague, C.T.1
O'Rahilly, S.2
-
19
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, and Groop LC. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34: 267-273, 2003.
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
20
-
-
33644678217
-
Fetal and neonatal exposure of mice to zidovudine (AZT) and low protein diet affects glucose homeostasis: Implications for AIDS prevention
-
Morten K, Field P, Ashley N, Williams KA, Harris D, Hartley M, Clark A, and Poulton J. Fetal and neonatal exposure of mice to zidovudine (AZT) and low protein diet affects glucose homeostasis: implications for AIDS prevention. Am J Physiol Endocrinol Metab 289: 1115-1118, 2005.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
, pp. 1115-1118
-
-
Morten, K.1
Field, P.2
Ashley, N.3
Williams, K.A.4
Harris, D.5
Hartley, M.6
Clark, A.7
Poulton, J.8
-
21
-
-
1642508654
-
The 16189 variant of mtDNA in type 2 diabetes: Towards a molecular mechanism
-
Morten K, Jen C, and Poulton J. The 16189 variant of mtDNA in type 2 diabetes: towards a molecular mechanism (Abstract). Diabet Med 20, Suppl 2: 13, 2003.
-
(2003)
Diabet Med
, vol.20
, Issue.2 SUPPL.
, pp. 13
-
-
Morten, K.1
Jen, C.2
Poulton, J.3
-
22
-
-
0023251188
-
Effect of restriction of placental growth on fetal and utero-placental metabolism
-
Owens JA, Falconer J, and Robinson JS. Effect of restriction of placental growth on fetal and utero-placental metabolism. J Dev Physiol 9: 225-238, 1987.
-
(1987)
J Dev Physiol
, vol.9
, pp. 225-238
-
-
Owens, J.A.1
Falconer, J.2
Robinson, J.S.3
-
23
-
-
0042410593
-
Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients
-
Pace CS, Martin AM, Hammond EL, Mamotte CD, Nolan DA, and Mallal SA. Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients. Antivir Ther 8: 323-331, 2003.
-
(2003)
Antivir Ther
, vol.8
, pp. 323-331
-
-
Pace, C.S.1
Martin, A.M.2
Hammond, E.L.3
Mamotte, C.D.4
Nolan, D.A.5
Mallal, S.A.6
-
24
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, and Mandarino LJ. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 100: 8466-8471, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
25
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, and Shulman GI. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300: 1140-1142, 2003.
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
DiPietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
26
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Garcia R, and Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350: 664-671, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
27
-
-
10844253892
-
Correction: No evidence of an association between the T16189C mtDNA variant and late onset dementia (Gibson et al)
-
author reply p. 957-958
-
Poulton J and Das S. Correction: no evidence of an association between the T16189C mtDNA variant and late onset dementia (Gibson et al). J Med Genet 41: 957, 2004 [author reply p. 957-958].
-
(2004)
J Med Genet
, vol.41
, pp. 957
-
-
Poulton, J.1
Das, S.2
-
28
-
-
0037096760
-
Type 2 diabetes is associated with a common mitochondrial variant: Evidence from a population-based case-control study
-
Poulton J, Luan J, Macaulay V, Hennings S, Mitchell J, and Wareham NJ. Type 2 diabetes is associated with a common mitochondrial variant: evidence from a population-based case-control study. Hum Mol Genet 11: 1581-1583, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1581-1583
-
-
Poulton, J.1
Luan, J.2
Macaulay, V.3
Hennings, S.4
Mitchell, J.5
Wareham, N.J.6
-
29
-
-
0029040769
-
Mitochondrial DNA, diabetes and pancreatic pathology in Kearns-Sayre syndrome
-
Poulton J, O'Rahilly S, Morten K, and Clark A. Mitochondrial DNA, diabetes and pancreatic pathology in Kearns-Sayre syndrome. Diabetologia 38: 868-871, 1995.
-
(1995)
Diabetologia
, vol.38
, pp. 868-871
-
-
Poulton, J.1
O'Rahilly, S.2
Morten, K.3
Clark, A.4
-
30
-
-
15644370476
-
A common mitochondrial DNA variant is associated with insulin resistance in adult life
-
Poulton J, Scott-Brown M, Cooper A, Marchington D, and Phillips D. A common mitochondrial DNA variant is associated with insulin resistance in adult life. Diabetologia 41: 54-58, 1998.
-
(1998)
Diabetologia
, vol.41
, pp. 54-58
-
-
Poulton, J.1
Scott-Brown, M.2
Cooper, A.3
Marchington, D.4
Phillips, D.5
-
31
-
-
0026462744
-
Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA
-
Reardon W, Ross RJ, Sweeney MG, Luxon LM, Pembrey ME, Harding AE, and Trembath RC. Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA. Lancet 340: 1376-1379, 1992.
-
(1992)
Lancet
, vol.340
, pp. 1376-1379
-
-
Reardon, W.1
Ross, R.J.2
Sweeney, M.G.3
Luxon, L.M.4
Pembrey, M.E.5
Harding, A.E.6
Trembath, R.C.7
-
32
-
-
0031671129
-
Phylogeography of mitochondrial DNA in western Europe
-
Richards MB, Macaulay VA, Bandelt HJ, and Sykes BC. Phylogeography of mitochondrial DNA in western Europe. Ann Hum Genet 62: 241-260, 1998.
-
(1998)
Ann Hum Genet
, vol.62
, pp. 241-260
-
-
Richards, M.B.1
Macaulay, V.A.2
Bandelt, H.J.3
Sykes, B.C.4
-
33
-
-
0029442618
-
Placental control of fetal growth
-
Robinson J, Chidzanja S, Kind K, Lok F, Owens P, and Owens J. Placental control of fetal growth. Reprod Fertil Dev 7: 333-344, 1995.
-
(1995)
Reprod Fertil Dev
, vol.7
, pp. 333-344
-
-
Robinson, J.1
Chidzanja, S.2
Kind, K.3
Lok, F.4
Owens, P.5
Owens, J.6
-
34
-
-
0033762782
-
Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes
-
Silva JP, Kohler M, Graff C, Oldfors A, Magnuson MA, Berggren PO, and Larsson NG. Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes. Nat Genet 26: 336-340, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 336-340
-
-
Silva, J.P.1
Kohler, M.2
Graff, C.3
Oldfors, A.4
Magnuson, M.A.5
Berggren, P.O.6
Larsson, N.G.7
-
35
-
-
0029966749
-
Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line; MIN6
-
Soejima A, Inoue K, Takai D, Kaneko M, Ishihara H, Oka Y, and Hayashi J. Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line; MIN6. J Biol Chem 271: 26194, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 26194
-
-
Soejima, A.1
Inoue, K.2
Takai, D.3
Kaneko, M.4
Ishihara, H.5
Oka, Y.6
Hayashi, J.7
-
36
-
-
0027477373
-
Mitochondrial gene mutations and diabetes mellitus
-
Sue CM, Holmes-Walker DJ, Morris JG, Boyages SC, Crimmins DS, and Byrne E. Mitochondrial gene mutations and diabetes mellitus [letter]. Lancet 341: 437-438, 1993.
-
(1993)
Lancet
, vol.341
, pp. 437-438
-
-
Sue, C.M.1
Holmes-Walker, D.J.2
Morris, J.G.3
Boyages, S.C.4
Crimmins, D.S.5
Byrne, E.6
-
37
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly YM, Gidlof S, Oldfors A, Wibom R, Tornell J, Jacobs HT, and Larsson NG. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417-423, 2004.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
38
-
-
0034736071
-
Uncoupling protein-1 mRNA expression in lipomas from patients bearing pathogenic mitochondrial DNA mutations
-
Vila MR, Gamez J, Solano A, Playan A, Schwartz S, Santorelli FM, Cervera C, Casali C, Montoya J, and Villarroya F. Uncoupling protein-1 mRNA expression in lipomas from patients bearing pathogenic mitochondrial DNA mutations. Biochem Biophys Res Commun 278: 800-802, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 800-802
-
-
Vila, M.R.1
Gamez, J.2
Solano, A.3
Playan, A.4
Schwartz, S.5
Santorelli, F.M.6
Cervera, C.7
Casali, C.8
Montoya, J.9
Villarroya, F.10
-
39
-
-
0025900541
-
Decreased mitochondrial gene expression in isolated islets of rats injected neonatally with streptozotocin
-
Welsh N, Paabo S, and Welsh M. Decreased mitochondrial gene expression in isolated islets of rats injected neonatally with streptozotocin. Diabetologia 34: 626-631, 1991.
-
(1991)
Diabetologia
, vol.34
, pp. 626-631
-
-
Welsh, N.1
Paabo, S.2
Welsh, M.3
-
40
-
-
20444428352
-
A bidirectional origin of replication maps to the major non-coding region of human mitochondrial DNA
-
Yakusawa T, Yang M, Jacobs H, and Holt I. A bidirectional origin of replication maps to the major non-coding region of human mitochondrial DNA. Mol Cell 18: 651-662, 2005.
-
(2005)
Mol Cell
, vol.18
, pp. 651-662
-
-
Yakusawa, T.1
Yang, M.2
Jacobs, H.3
Holt, I.4
|