메뉴 건너뛰기




Volumn 40, Issue 10, 2003, Pages 773-780

Effect of the peroxisome proliferates activated receptor-γ gene Pro12Ala variant on body mass index: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ALANINE; CELL RECEPTOR; PROLINE; TRANSCRIPTION FACTOR;

EID: 0142209179     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (190)

References (44)
  • 1
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000;405:421-4.
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 3
    • 0032189782 scopus 로고    scopus 로고
    • Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
    • Ristow M, Muller-Wieland D, Pfeiffer A, Krone W, Kahn CR. Obesity associated with a mutation in a genetic regulator of adipocyte differentiation: N Engl J Med 1998;339:953-9.
    • (1998) N Engl J Med , vol.339 , pp. 953-959
    • Ristow, M.1    Muller-Wieland, D.2    Pfeiffer, A.3    Krone, W.4    Kahn, C.R.5
  • 8
    • 0036071296 scopus 로고    scopus 로고
    • Testing for population subdivision and association in four case-control studies
    • Ardlie KG, Lunetta KL, Seielstad M. Testing for population subdivision and association in four case-control studies. Am J Hum Genet 2002;71:304-11.
    • (2002) Am J Hum Genet , vol.71 , pp. 304-311
    • Ardlie, K.G.1    Lunetta, K.L.2    Seielstad, M.3
  • 9
    • 0345164399 scopus 로고    scopus 로고
    • Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: Identification of a Pro12Ala PPAR gamma 2 missense mutation
    • Yen CJ, Beamer BA, Negri C, Silver K, Brown KA, Yarnall DP, Burns DK, Roth J, Shuldiner AR. Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation. Biochem Biophys Res Commun 1997;241:270-24.
    • (1997) Biochem Biophys Res Commun , vol.241 , pp. 270-324
    • Yen, C.J.1    Beamer, B.A.2    Negri, C.3    Silver, K.4    Brown, K.A.5    Yarnall, D.P.6    Burns, D.K.7    Roth, J.8    Shuldiner, A.R.9
  • 10
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, Laakso M, Fujimoto W, Auwerx J. A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 1998;20:284-7.
    • (1998) Nat Genet , vol.20 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3    Pihlajamaki, J.4    Mykkanen, L.5    Kuusisto, J.6    Laakso, M.7    Fujimoto, W.8    Auwerx, J.9
  • 12
    • 0031667127 scopus 로고    scopus 로고
    • Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations
    • Beamer BA, Yen CJ, Andersen RE, Muller D, Elahi D, Cheskin LJ, Andres R, Roth J, Shuldiner AR. Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations. Diabetes 1998;47:1806-8.
    • (1998) Diabetes , vol.47 , pp. 1806-1808
    • Beamer, B.A.1    Yen, C.J.2    Andersen, R.E.3    Muller, D.4    Elahi, D.5    Cheskin, L.J.6    Andres, R.7    Roth, J.8    Shuldiner, A.R.9
  • 13
    • 0032781890 scopus 로고    scopus 로고
    • Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): Divergent modulating effects on body mass index in obese and lean Caucasian men
    • Ek J, Urhammer SA, Sorensen TI, Andersen T, Auwerx J, Pedersen O. Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men. Diabetologia 1999,42:892-5.
    • (1999) Diabetologia , vol.42 , pp. 892-895
    • Ek, J.1    Urhammer, S.A.2    Sorensen, T.I.3    Andersen, T.4    Auwerx, J.5    Pedersen, O.6
  • 14
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 15
  • 17
    • 0033060302 scopus 로고    scopus 로고
    • Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes
    • Vaccaro O, Mancini FP, Ruffa G, Sabatino L, Colantuoni V, Riccardi G. Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes. Diabetes 1999;48:1466-8.
    • (1999) Diabetes , vol.48 , pp. 1466-1468
    • Vaccaro, O.1    Mancini, F.P.2    Ruffa, G.3    Sabatino, L.4    Colantuoni, V.5    Riccardi, G.6
  • 18
    • 0033582258 scopus 로고    scopus 로고
    • Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus
    • Ringel J, Engeli S, Distler A, Sharma AM. Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus. Biochem Biophys Res Commun 1999;254:450-3.
    • (1999) Biochem Biophys Res Commun , vol.254 , pp. 450-453
    • Ringel, J.1    Engeli, S.2    Distler, A.3    Sharma, A.M.4
  • 22
    • 0033787614 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma 2 Pro12Ala gene variant is strongly associated with larger body mass in the Taiwanese
    • Lei HH, Chen MH, Yang WS, Chiu MC, Chen MC, Tai TY, Chuang LM. Peroxisome proliferator-activated receptor gamma 2 Pro12Ala gene variant is strongly associated with larger body mass in the Taiwanese. Metabolism 2000;49:1267-70.
    • (2000) Metabolism , vol.49 , pp. 1267-1270
    • Lei, H.H.1    Chen, M.H.2    Yang, W.S.3    Chiu, M.C.4    Chen, M.C.5    Tai, T.Y.6    Chuang, L.M.7
  • 23
    • 0001491179 scopus 로고    scopus 로고
    • Impact of the peroxisome proliferator activated receptor gamma2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus
    • Meirhaeghe A, Fajas L, Helbecque N, Cottel D, Auwerx J, Deeb SS, Amouyel P. Impact of the peroxisome proliferator activated receptor gamma2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus. Int J Obes Relat Metab Disord 2000;24:195-9.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. 195-199
    • Meirhaeghe, A.1    Fajas, L.2    Helbecque, N.3    Cottel, D.4    Auwerx, J.5    Deeb, S.S.6    Amouyel, P.7
  • 24
    • 0034186496 scopus 로고    scopus 로고
    • Significance of Pro12Ala mutation in peroxisome proliferator-activated receptor-gamma2 in Korean diabetic and obese subjects
    • Oh EY, Min KM, Chung JH, Min YK, Lee MS, Kim KW, Lee MK. Significance of Pro12Ala mutation in peroxisome proliferator-activated receptor-gamma2 in Korean diabetic and obese subjects. J Clin Endocrinol Metab 2000;85:1801-4.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1801-1804
    • Oh, E.Y.1    Min, K.M.2    Chung, J.H.3    Min, Y.K.4    Lee, M.S.5    Kim, K.W.6    Lee, M.K.7
  • 25
    • 0033866105 scopus 로고    scopus 로고
    • The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma2 gene is not associated with postprandial responses to glucose or fat tolerance tests in young healthy subjects: The European Atherosclerosis Research Study II
    • Poirier O, Nicaud V, Combien F, Tiret L. The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma2 gene is not associated with postprandial responses to glucose or fat tolerance tests in young healthy subjects: the European Atherosclerosis Research Study II. J Mol Med 2000;78:346-51.
    • (2000) J Mol Med , vol.78 , pp. 346-351
    • Poirier, O.1    Nicaud, V.2    Combien, F.3    Tiret, L.4
  • 26
    • 0035163768 scopus 로고    scopus 로고
    • Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: A SAPPHIRe study
    • Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.
    • Chuang LM, Hsiung CA, Chen YD, Ho LT, Sheu WH, Pei D, Nakatsuka CH, Cox D, Pratt RE, Lei HH, Tai TY. Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance. J Mol Med 2001;79:656-64.
    • (2001) J Mol Med , vol.79 , pp. 656-664
    • Chuang, L.M.1    Hsiung, C.A.2    Chen, Y.D.3    Ho, L.T.4    Sheu, W.H.5    Pei, D.6    Nakatsuka, C.H.7    Cox, D.8    Pratt, R.E.9    Lei, H.H.10    Tai, T.Y.11
  • 27
    • 17944362462 scopus 로고    scopus 로고
    • Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant Caucasians
    • Ek J, Andersen G, Urhammer SA, Hansen L, Carstensen B, Borch-Johnsen K, Drivsholm T, Berglund L, Hansen T, Lithell H, Pedersen O. Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant Caucasians. Diabetologia 2001;44:1170-6.
    • (2001) Diabetologia , vol.44 , pp. 1170-1176
    • Ek, J.1    Andersen, G.2    Urhammer, S.A.3    Hansen, L.4    Carstensen, B.5    Borch-Johnsen, K.6    Drivsholm, T.7    Berglund, L.8    Hansen, T.9    Lithell, H.10    Pedersen, O.11
  • 29
    • 0034945883 scopus 로고    scopus 로고
    • Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long- Term weight change in Finnish non-diabetic subjects
    • Lindi V, Sivenius K, Niskanen L, Laakso M, Uusitupa MI. Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long- term weight change in Finnish non-diabetic subjects. Diabetologia 2001;44:925-6.
    • (2001) Diabetologia , vol.44 , pp. 925-926
    • Lindi, V.1    Sivenius, K.2    Niskanen, L.3    Laakso, M.4    Uusitupa, M.I.5
  • 31
    • 0034974186 scopus 로고    scopus 로고
    • Frequency and significance of Pro12Ala and Pro115Gln polymorphism in gene for peroxisome proliferation-activated receptor-gamma regarding metabolic parameters in a Caucasian cohort
    • Schaffler A, Barth N, Schmitz G, Zietz B, Palitzsch KD, Scholmerich J. Frequency and significance of Pro12Ala and Pro115Gln polymorphism in gene for peroxisome proliferation-activated receptor-gamma regarding metabolic parameters in a Caucasian cohort. Endocrine 2001;14:369-73.
    • (2001) Endocrine , vol.14 , pp. 369-373
    • Schaffler, A.1    Barth, N.2    Schmitz, G.3    Zietz, B.4    Palitzsch, K.D.5    Scholmerich, J.6
  • 32
    • 0035062772 scopus 로고    scopus 로고
    • A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidoemia in obesity
    • Swarbrick MM, Chapman CM, McQuillan BM, Hung J, Thompson PL, Beilby JP. A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidoemia in obesity. Eur J Endocrinol 2001;144:277-82.
    • (2001) Eur J Endocrinol , vol.144 , pp. 277-282
    • Swarbrick, M.M.1    Chapman, C.M.2    McQuillan, B.M.3    Hung, J.4    Thompson, P.L.5    Beilby, J.P.6
  • 35
    • 0036314819 scopus 로고    scopus 로고
    • The proline 12 alanine substitution in the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower lipoprotein lipase activity in vivo
    • Schneider J, Kreuzer J, Hamann A, Nawroth PP, Dugi KA. The proline 12 alanine substitution in the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower lipoprotein lipase activity in vivo. Diabetes 2002;51:867-70.
    • (2002) Diabetes , vol.51 , pp. 867-870
    • Schneider, J.1    Kreuzer, J.2    Hamann, A.3    Nawroth, P.P.4    Dugi, K.A.5
  • 36
    • 0036162822 scopus 로고    scopus 로고
    • Reduced lipolysis as possible cause for greater weight gain in subjects with the Pro12Ala polymorphism in PPARgamma2?
    • Stumvoll M, Haring H. Reduced lipolysis as possible cause for greater weight gain in subjects with the Pro12Ala polymorphism in PPARgamma2? Diabetologia 2002,45:152-3.
    • (2002) Diabetologia , vol.45 , pp. 152-153
    • Stumvoll, M.1    Haring, H.2
  • 37
    • 0036169343 scopus 로고    scopus 로고
    • Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity
    • Stumvoll M, Stefan N, Fritsche A, Madaus A, Tschritter O, Koch M, Machicao F, Haring H. Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity. J Mol Med 2002;80:33-8.
    • (2002) J Mol Med , vol.80 , pp. 33-38
    • Stumvoll, M.1    Stefan, N.2    Fritsche, A.3    Madaus, A.4    Tschritter, O.5    Koch, M.6    Machicao, F.7    Haring, H.8
  • 41
    • 0034175511 scopus 로고    scopus 로고
    • An evaluation of homogeneity tests in meta-analyses in pain using simulations of individual patient data
    • Gavaghan DJ, Moore RA, McQuay HJ. An evaluation of homogeneity tests in meta-analyses in pain using simulations of individual patient data. Pain 2000;85:415-24.
    • (2000) Pain , vol.85 , pp. 415-424
    • Gavaghan, D.J.1    Moore, R.A.2    McQuay, H.J.3
  • 42
    • 4243353569 scopus 로고    scopus 로고
    • Comment: Studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort - Homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome
    • Frederiksen I, Brodbaek K, Fenger M, Jorgensen T, Borch-Johnsen K, Modsbad S, Urhammer SA. Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome. J Clin Endocrinol Metab 2002;87:3989-92.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3989-3992
    • Frederiksen, I.1    Brodbaek, K.2    Fenger, M.3    Jorgensen, T.4    Borch-Johnsen, K.5    Modsbad, S.6    Urhammer, S.A.7
  • 43
    • 0030977450 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin ond glucocorticoids
    • Vidal-Puig AJ, Considine RV, Jimenez-Linan M, Wermon A, Pories WJ, Caro JF, Flier JS. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin ond glucocorticoids. J Clin Invest 1997;99:2416-22.
    • (1997) J Clin Invest , vol.99 , pp. 2416-2422
    • Vidal-Puig, A.J.1    Considine, R.V.2    Jimenez-Linan, M.3    Wermon, A.4    Pories, W.J.5    Caro, J.F.6    Flier, J.S.7
  • 44
    • 0030877565 scopus 로고    scopus 로고
    • Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgomma1 and -2 isoforms and influence of insulin
    • Werman A, Hollenberg A, Solanes G, Bjorbaek C, Vidal-Puig AJ, Flier JS. Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgomma1 and -2 isoforms and influence of insulin. J Biol Chem 1997;272:20230-5.
    • (1997) J Biol Chem , vol.272 , pp. 20230-20235
    • Werman, A.1    Hollenberg, A.2    Solanes, G.3    Bjorbaek, C.4    Vidal-Puig, A.J.5    Flier, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.