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Volumn 327, Issue 7407, 2003, Pages 143-147

Science, medicine, and the future: Cirrhosis: New research provides a basis for rational and targeted treatments

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTIOXIDANT; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN RECEPTOR ANTAGONIST; ENZYME INHIBITOR; GAMMA INTERFERON; GLIOTOXIN; INTERLEUKIN 10; METALLOPROTEINASE; MONOCLONAL ANTIBODY; NERVE GROWTH FACTOR; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PLATELET DERIVED GROWTH FACTOR; RELAXIN; SCATTER FACTOR; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; BIOLOGICAL MARKER; MATRIX METALLOPROTEINASE;

EID: 0038455747     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (166)

References (26)
  • 2
    • 0036116213 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis (NASH): Where are we now and where are we going?
    • Day CP. Non-alcoholic steatohepatitis (NASH): where are we now and where are we going? Gut 2002;50:585-8.
    • (2002) Gut , vol.50 , pp. 585-588
    • Day, C.P.1
  • 3
    • 0038452275 scopus 로고    scopus 로고
    • National Center for Chronic Disease Prevention and Health Promotion. US Obesity Trends 1985 to 2000. www.cdc.gov/nccdphp/dnpa/obesity/trend/maps/index.htm (accessed 1 Jul 2003).
    • US Obesity Trends 1985 to 2000
  • 4
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis: Mechanisms and treatment strategies
    • Friedman SL. The cellular basis of hepatic fibrosis: mechanisms and treatment strategies. N Engl J Med 1993;328:1828-35.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 5
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-50.
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 6
    • 0001520008 scopus 로고
    • Hepatic lipocytes: The principal collagen-producing cells of normal rat liver
    • Friedman SL, Roll FJ, Boyles J, Bissell DM. Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci USA 1985;82:8681-5.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8681-8685
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3    Bissell, D.M.4
  • 7
    • 0025000652 scopus 로고
    • Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
    • Maher JJ, McGuire RF. Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest 1990;86:1641-8.
    • (1990) J Clin Invest , vol.86 , pp. 1641-1648
    • Maher, J.J.1    McGuire, R.F.2
  • 8
    • 0031972755 scopus 로고    scopus 로고
    • Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells
    • Wang SC, Ohata M, Schrum L, Rippe RA, Tsukamoto H. Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells. J Biol Chem 1998;273:302-8.
    • (1998) J Biol Chem , vol.273 , pp. 302-308
    • Wang, S.C.1    Ohata, M.2    Schrum, L.3    Rippe, R.A.4    Tsukamoto, H.5
  • 10
    • 0034022483 scopus 로고    scopus 로고
    • Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: A pilot trial of interferon nonresponders
    • Nelson DR, Lauwers GY, Lau JY, Davis GL. Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: a pilot trial of interferon nonresponders. Gastroenterology 2000;118:655-60.
    • (2000) Gastroenterology , vol.118 , pp. 655-660
    • Nelson, D.R.1    Lauwers, G.Y.2    Lau, J.Y.3    Davis, G.L.4
  • 11
    • 0037386110 scopus 로고    scopus 로고
    • Anti-tumour necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis
    • Tilg H, Jalan R, Kaser A, Davies NA, Offner FA, Hodges SJ, et al. Anti-tumour necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis. J Hepatol 2003;38:419-25.
    • (2003) J Hepatol , vol.38 , pp. 419-425
    • Tilg, H.1    Jalan, R.2    Kaser, A.3    Davies, N.A.4    Offner, F.A.5    Hodges, S.J.6
  • 12
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med 1994;10:1286-92.
    • (1994) N Engl J Med , vol.10 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 13
    • 0026778310 scopus 로고
    • Transforming growth factor beta in disease: The dark side of tissue repair
    • Border WA, Ruoslahti E. Transforming growth factor beta in disease: the dark side of tissue repair. J Clin Invest 1992;90:1-7.
    • (1992) J Clin Invest , vol.90 , pp. 1-7
    • Border, W.A.1    Ruoslahti, E.2
  • 14
    • 0026676859 scopus 로고
    • Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease
    • Border WA, Noble NA, Yamamoto T, Harper JR, Yamaguchi Y, Pierschbacher MD, et al. Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature 1992;360:361-4.
    • (1992) Nature , vol.360 , pp. 361-364
    • Border, W.A.1    Noble, N.A.2    Yamamoto, T.3    Harper, J.R.4    Yamaguchi, Y.5    Pierschbacher, M.D.6
  • 15
    • 0033607304 scopus 로고    scopus 로고
    • In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: A potential new therapy for hepatic fibrosis
    • George J, Roulot D, Koteliansky VE, Bissell DM. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci USA 1999;96:12719-24.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12719-12724
    • George, J.1    Roulot, D.2    Koteliansky, V.E.3    Bissell, D.M.4
  • 16
    • 0034809804 scopus 로고    scopus 로고
    • Hepatic stellate cells as a target for the treatment of liver fibrosis
    • Bataller R, Brenner D. Hepatic stellate cells as a target for the treatment of liver fibrosis. Seminars in Liver Disease 2001;21:437-51.
    • (2001) Seminars in Liver Disease , vol.21 , pp. 437-451
    • Bataller, R.1    Brenner, D.2
  • 17
    • 0034814405 scopus 로고    scopus 로고
    • Extracellular matrix degradation and the role of hepatic stellate cells
    • Benyon RC, Arthur MJP. Extracellular matrix degradation and the role of hepatic stellate cells. Seminars in Liver Disease 2001;21:373-84.
    • (2001) Seminars in Liver Disease , vol.21 , pp. 373-384
    • Benyon, R.C.1    Arthur, M.J.P.2
  • 18
    • 0030030039 scopus 로고    scopus 로고
    • Expression of tissue inhibitor of metalloproteinases-1 and -2 is increased in fibrotic human liver
    • Benyon RC, Iredale JP, Goddard S, Winwood PJ, Arthur MJP. Expression of tissue inhibitor of metalloproteinases-1 and -2 is increased in fibrotic human liver. Gastroenterology 1996;110:821-31.
    • (1996) Gastroenterology , vol.110 , pp. 821-831
    • Benyon, R.C.1    Iredale, J.P.2    Goddard, S.3    Winwood, P.J.4    Arthur, M.J.P.5
  • 19
    • 0032146551 scopus 로고    scopus 로고
    • Mechanisms of spontaneous resolution of rat liver fibrosis: Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inbibitors
    • Iredale JP, Benyon RC, Pickering J, McCullen M, Northrop M, Pawley S, et al. Mechanisms of spontaneous resolution of rat liver fibrosis: hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inbibitors. J Clin Invest 1998;102:538-49.
    • (1998) J Clin Invest , vol.102 , pp. 538-549
    • Iredale, J.P.1    Benyon, R.C.2    Pickering, J.3    McCullen, M.4    Northrop, M.5    Pawley, S.6
  • 20
    • 0035742752 scopus 로고    scopus 로고
    • Decreasing fibrogenesis: An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B
    • Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burkhardt E, et al. Decreasing fibrogenesis: an immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B. J Hepatol 2001;35:749-55.
    • (2001) J Hepatol , vol.35 , pp. 749-755
    • Kweon, Y.O.1    Goodman, Z.D.2    Dienstag, J.L.3    Schiff, E.R.4    Brown, N.A.5    Burkhardt, E.6
  • 21
    • 0036242165 scopus 로고    scopus 로고
    • Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
    • Poynard T, McHutchison J, Manns M, Trepo C, Lindsay K, Goodman Z, et al. Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 2002;122:1303-13.
    • (2002) Gastroenterology , vol.122 , pp. 1303-1313
    • Poynard, T.1    McHutchison, J.2    Manns, M.3    Trepo, C.4    Lindsay, K.5    Goodman, Z.6
  • 22
    • 0034830886 scopus 로고    scopus 로고
    • Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
    • Wright MC, Issa R, Smart DE, Trim N, Murray GI, Primrose JN, et al. Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 2001;121:685-98.
    • (2001) Gastroenterology , vol.121 , pp. 685-698
    • Wright, M.C.1    Issa, R.2    Smart, D.E.3    Trim, N.4    Murray, G.I.5    Primrose, J.N.6
  • 23
    • 0037308337 scopus 로고    scopus 로고
    • Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat
    • Imuro Y, Nishio T, Morimoto T, Nitta T, Stefanovic B, Choi SK, et al Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat. Gastroenterology 2003;124:445-58.
    • (2003) Gastroenterology , vol.124 , pp. 445-458
    • Imuro, Y.1    Nishio, T.2    Morimoto, T.3    Nitta, T.4    Stefanovic, B.5    Choi, S.K.6
  • 24
    • 0034804406 scopus 로고    scopus 로고
    • Hepatic blood flow regulation by stellate cells in normal and injured liver
    • Rockey DC. Hepatic blood flow regulation by stellate cells in normal and injured liver. Seminars in Liver Disease 2002;21:337-49.
    • (2002) Seminars in Liver Disease , vol.21 , pp. 337-349
    • Rockey, D.C.1
  • 25
    • 0001090295 scopus 로고    scopus 로고
    • Automated assays of serum markers of liver fibrosis predict histological hepatic fibrosis
    • Rosenberg W, Burt A, Becka M, Voelker M, Arthur MJE Automated assays of serum markers of liver fibrosis predict histological hepatic fibrosis. Hepatology 2000;32:183A.
    • (2000) Hepatology , vol.32
    • Rosenberg, W.1    Burt, A.2    Becka, M.3    Voelker, M.4    Arthur, M.J.E.5
  • 26
    • 0012235679 scopus 로고    scopus 로고
    • Reversing hepatic fibrosis
    • Friedman SL, Arthur MJP. Reversing hepatic fibrosis. Sci Med 2002;8:194-205.
    • (2002) Sci Med , vol.8 , pp. 194-205
    • Friedman, S.L.1    Arthur, M.J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.