-
3
-
-
0034332342
-
Who gets alcoholic liver disease: Nature or nurture?
-
Day CP: Who gets alcoholic liver disease: nature or nurture? J R Coll Physicians Lond 2000;34:557-562.
-
(2000)
J R Coll Physicians Lond
, vol.34
, pp. 557-562
-
-
Day, C.P.1
-
4
-
-
0030296956
-
Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis
-
Reeves HL, Burt AD, Wood S, Day CP: Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis. J Hepatol 1996;25:677-683.
-
(1996)
J Hepatol
, vol.25
, pp. 677-683
-
-
Reeves, H.L.1
Burt, A.D.2
Wood, S.3
Day, C.P.4
-
5
-
-
0021826574
-
Perivenular fibrosis as precursor lesion of cirrhosis
-
Worner TM, Lieber CS: Perivenular fibrosis as precursor lesion of cirrhosis. JAMA 1985;254:627-630.
-
(1985)
JAMA
, vol.254
, pp. 627-630
-
-
Worner, T.M.1
Lieber, C.S.2
-
7
-
-
0023025701
-
Histologic spectrum of alcoholic liver disease
-
MacSween RN, Burt AD: Histologic spectrum of alcoholic liver disease. Semin Liver Dis 1986;6:221-232.
-
(1986)
Semin Liver Dis
, vol.6
, pp. 221-232
-
-
MacSween, R.N.1
Burt, A.D.2
-
8
-
-
0021173477
-
Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis
-
Sorensen TI, Orholm M, Bentsen KD, Hoybye G, Eghoje K, Christoffersen P: Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis. Lancet 1984;ii:241-244.
-
(1984)
Lancet
, vol.2
, pp. 241-244
-
-
Sorensen, T.I.1
Orholm, M.2
Bentsen, K.D.3
Hoybye, G.4
Eghoje, K.5
Christoffersen, P.6
-
9
-
-
0029165057
-
Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
-
Teli MR, Day CP, Burt AD, Bennett MK, James OF: Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet 1995;346:987-990.
-
(1995)
Lancet
, vol.346
, pp. 987-990
-
-
Teli, M.R.1
Day, C.P.2
Burt, A.D.3
Bennett, M.K.4
James, O.F.5
-
10
-
-
0034605495
-
The continuing epidemic of obesity in the United States
-
Mokdad AH, Serdula MK, Dietz WH, Bowman BA, Marks JS, Koplan JP: The continuing epidemic of obesity in the United States. JAMA 2000;284:1650-1651.
-
(2000)
JAMA
, vol.284
, pp. 1650-1651
-
-
Mokdad, A.H.1
Serdula, M.K.2
Dietz, W.H.3
Bowman, B.A.4
Marks, J.S.5
Koplan, J.P.6
-
11
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P: Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
12
-
-
0033982172
-
Prevalence of and risk factors for hepatic steatosis in northern Italy
-
Bellentani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, Cristanini G, Tiribelli C: Prevalence of and risk factors for hepatic steatosis in northern Italy. Ann Intern Med 2000;132:112-117.
-
(2000)
Ann Intern Med
, vol.132
, pp. 112-117
-
-
Bellentani, S.1
Saccoccio, G.2
Masutti, F.3
Croce, L.S.4
Brandi, G.5
Sasso, F.6
Cristanini, G.7
Tiribelli, C.8
-
13
-
-
0036185832
-
Risk factors of fibrosis in alcohol-induced liver disease
-
Raynard B, Balian A, Fallik D, Capron F, Bedossa P, Chaput JC, Naveau S: Risk factors of fibrosis in alcohol-induced liver disease. Hepatology 2002;35: 635-638.
-
(2002)
Hepatology
, vol.35
, pp. 635-638
-
-
Raynard, B.1
Balian, A.2
Fallik, D.3
Capron, F.4
Bedossa, P.5
Chaput, J.C.6
Naveau, S.7
-
14
-
-
0031012322
-
Excess weight risk factor for alcoholic liver disease
-
Naveau S, Giraud V, Borotto E, Aubert A, Capron F, Chaput JC: Excess weight risk factor for alcoholic liver disease. Hepatology 1997;25:108-111.
-
(1997)
Hepatology
, vol.25
, pp. 108-111
-
-
Naveau, S.1
Giraud, V.2
Borotto, E.3
Aubert, A.4
Capron, F.5
Chaput, J.C.6
-
15
-
-
2342419920
-
Long term prognosis of fatty liver: Risk of chronic liver disease and death
-
Dam-Larsen S, Franzmann M, Andersen IB, Christoffersen P, Jensen LB, Sorensen TI, Becker U, Bendtsen F: Long term prognosis of fatty liver: risk of chronic liver disease and death. Gut 2004;53:750-755.
-
(2004)
Gut
, vol.53
, pp. 750-755
-
-
Dam-Larsen, S.1
Franzmann, M.2
Andersen, I.B.3
Christoffersen, P.4
Jensen, L.B.5
Sorensen, T.I.6
Becker, U.7
Bendtsen, F.8
-
16
-
-
0015166045
-
Natural history of alcoholic hepatitis. II. The long-term prognosis
-
Alexander JF, Lischner MW, Galambos JT: Natural history of alcoholic hepatitis. II. The long-term prognosis. Am J Gastroenterol 1971;56:515-525.
-
(1971)
Am J Gastroenterol
, vol.56
, pp. 515-525
-
-
Alexander, J.F.1
Lischner, M.W.2
Galambos, J.T.3
-
17
-
-
0023813855
-
Factors determining cirrhosis in alcoholic liver disease
-
Bird GL, Williams R: Factors determining cirrhosis in alcoholic liver disease. Mol Aspects Med 1988;10:97-105.
-
(1988)
Mol Aspects Med
, vol.10
, pp. 97-105
-
-
Bird, G.L.1
Williams, R.2
-
18
-
-
0030998305
-
Alcoholic liver disease: Natural history
-
Diehl AM: Alcoholic liver disease: natural history. Liver Transpl Surg 1997;3:206-211.
-
(1997)
Liver Transpl Surg
, vol.3
, pp. 206-211
-
-
Diehl, A.M.1
-
19
-
-
0029941556
-
Survival and prognostic factors in patients with severe alcoholic hepatitis treated with prednisolone
-
Mathurin P, Duchatelle V, Ramond MJ, Degott C, Bedossa P, Erlinger S, Benhamou JP, Chaput JC, Rueff B, Poynard T: Survival and prognostic factors in patients with severe alcoholic hepatitis treated with prednisolone. Gastroenterology 1996;110:1847-1853.
-
(1996)
Gastroenterology
, vol.110
, pp. 1847-1853
-
-
Mathurin, P.1
Duchatelle, V.2
Ramond, M.J.3
Degott, C.4
Bedossa, P.5
Erlinger, S.6
Benhamou, J.P.7
Chaput, J.C.8
Rueff, B.9
Poynard, T.10
-
20
-
-
0015461834
-
Alcoholic hepatitis: Its therapy and prognosis
-
Galambos JT: Alcoholic hepatitis: its therapy and prognosis. Prog Liver Dis 1972;4:567-588.
-
(1972)
Prog Liver Dis
, vol.4
, pp. 567-588
-
-
Galambos, J.T.1
-
21
-
-
0022657973
-
Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage
-
Pares A, Caballeria J, Bruguera M, Torres M, Rodes J: Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage. J Hepatol 1986;2:33-42.
-
(1986)
J Hepatol
, vol.2
, pp. 33-42
-
-
Pares, A.1
Caballeria, J.2
Bruguera, M.3
Torres, M.4
Rodes, J.5
-
22
-
-
0028678058
-
The prognosis and outcome of alcoholic liver disease
-
Morgan MY: The prognosis and outcome of alcoholic liver disease. Alcohol Alcohol Suppl 1994;2:335-343.
-
(1994)
Alcohol Alcohol Suppl
, vol.2
, pp. 335-343
-
-
Morgan, M.Y.1
-
23
-
-
0033003299
-
Evaluation of efficacy of liver transplantation in alcoholic cirrhosis using matched and simulated controls: 5-Year survival
-
Multi-centre group
-
Poynard T, Naveau S, Doffoel M, Boudjema K, Vanlemmens C, Mantion G, Messner M, Launois B, Samuel D, Cherqui D, Pageaux G, Bernard PH, Calmus Y, Zarski JP, Miguet JP, Chaput JC: Evaluation of efficacy of liver transplantation in alcoholic cirrhosis using matched and simulated controls: 5-year survival. Multi-centre group. J Hepatol 1999;30:1130-1137.
-
(1999)
J Hepatol
, vol.30
, pp. 1130-1137
-
-
Poynard, T.1
Naveau, S.2
Doffoel, M.3
Boudjema, K.4
Vanlemmens, C.5
Mantion, G.6
Messner, M.7
Launois, B.8
Samuel, D.9
Cherqui, D.10
Pageaux, G.11
Bernard, P.H.12
Calmus, Y.13
Zarski, J.P.14
Miguet, J.P.15
Chaput, J.C.16
-
24
-
-
23844453758
-
Liver transplantation in alcoholic patients
-
Burra P, Lucey MR: Liver transplantation in alcoholic patients. Transpl Int 2005;18:491-498.
-
(2005)
Transpl Int
, vol.18
, pp. 491-498
-
-
Burra, P.1
Lucey, M.R.2
-
25
-
-
0023757265
-
Orthotopic liver transplantation for alcoholic cirrhosis
-
Starzl TE, Van Thiel D, Tzakis AG, Iwatsuki S, Todo S, Marsh JW, Koneru B, Staschak S, Stieber A, Gordon RD: Orthotopic liver transplantation for alcoholic cirrhosis. JAMA 1988;260:2542-2544.
-
(1988)
JAMA
, vol.260
, pp. 2542-2544
-
-
Starzl, T.E.1
Van Thiel, D.2
Tzakis, A.G.3
Iwatsuki, S.4
Todo, S.5
Marsh, J.W.6
Koneru, B.7
Staschak, S.8
Stieber, A.9
Gordon, R.D.10
-
26
-
-
0026606625
-
Selection for and outcome of liver transplantation in alcoholic liver disease
-
Lucey MR, Merion RM, Henley KS, Campbell DA Jr, Turcotte JG, Nostrant TT, Blow FC, Beresford TP: Selection for and outcome of liver transplantation in alcoholic liver disease. Gastroenterology 1992;102:1736-1741.
-
(1992)
Gastroenterology
, vol.102
, pp. 1736-1741
-
-
Lucey, M.R.1
Merion, R.M.2
Henley, K.S.3
Campbell Jr., D.A.4
Turcotte, J.G.5
Nostrant, T.T.6
Blow, F.C.7
Beresford, T.P.8
-
27
-
-
0021294880
-
National Institutes of Health Consensus Development Conference Statement: Liver transplantation - June 20-23, 1983
-
National Institutes of Health Consensus Development Conference Statement: liver transplantation - June 20-23, 1983. Hepatology 1984;4(suppl):107S-110S.
-
(1984)
Hepatology
, vol.4
, Issue.SUPPL.
-
-
-
28
-
-
16544381987
-
Liver transplantation for alcoholic liver disease
-
Anantharaju A, Van Thiel DH: Liver transplantation for alcoholic liver disease. Alcohol Res Health 2003;27:257-268.
-
(2003)
Alcohol Res Health
, vol.27
, pp. 257-268
-
-
Anantharaju, A.1
Van Thiel, D.H.2
-
29
-
-
0000156898
-
Effects of prolonged ethanol intake: Production of fatty liver despite adequate diets
-
Lieber CS, Jones DP, Decarli LM: Effects of prolonged ethanol intake: production of fatty liver despite adequate diets. J Clin Invest 1965;44:1009-1021.
-
(1965)
J Clin Invest
, vol.44
, pp. 1009-1021
-
-
Lieber, C.S.1
Jones, D.P.2
Decarli, L.M.3
-
30
-
-
0019796717
-
Attenuation of the ethanol-induced hepatic redox change after chronic alcohol consumption in baboons: Metabolic consequences in vivo and in vitro
-
Salaspuro MP, Shaw S, Jayatilleke E, Ross WA, Lieber CS: Attenuation of the ethanol-induced hepatic redox change after chronic alcohol consumption in baboons: metabolic consequences in vivo and in vitro. Hepatology 1981;1:33-38.
-
(1981)
Hepatology
, vol.1
, pp. 33-38
-
-
Salaspuro, M.P.1
Shaw, S.2
Jayatilleke, E.3
Ross, W.A.4
Lieber, C.S.5
-
31
-
-
9644290860
-
The role of AMP-activated protein kinase in the action of ethanol in the liver
-
You M, Matsumoto M, Pacold CM, Cho WK, Crabb DW: The role of AMP-activated protein kinase in the action of ethanol in the liver. Gastroenterology 2004;127:1798-1808.
-
(2004)
Gastroenterology
, vol.127
, pp. 1798-1808
-
-
You, M.1
Matsumoto, M.2
Pacold, C.M.3
Cho, W.K.4
Crabb, D.W.5
-
32
-
-
0037047284
-
Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
-
You M, Fischer M, Deeg MA, Crabb DW: Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J Biol Chem 2002;277:29342-29347.
-
(2002)
J Biol Chem
, vol.277
, pp. 29342-29347
-
-
You, M.1
Fischer, M.2
Deeg, M.A.3
Crabb, D.W.4
-
33
-
-
0032491614
-
Peroxisome proliferator-activated receptor alpha-isofbrm deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
-
Costet P, Legendre C, More J, Edgar A, Galtier P, Pineau T: Peroxisome proliferator-activated receptor alpha-isofbrm deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem 1998;273:29577-29585.
-
(1998)
J Biol Chem
, vol.273
, pp. 29577-29585
-
-
Costet, P.1
Legendre, C.2
More, J.3
Edgar, A.4
Galtier, P.5
Pineau, T.6
-
34
-
-
0042847330
-
Peroxisome proliferator-activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice
-
Fischer M, You M, Matsumoto M, Crabb DW: Peroxisome proliferator- activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice. J Biol Chem 2003;278:27997-28004.
-
(2003)
J Biol Chem
, vol.278
, pp. 27997-28004
-
-
Fischer, M.1
You, M.2
Matsumoto, M.3
Crabb, D.W.4
-
35
-
-
0031947715
-
Steatohepatitis: A tale of two 'hits'?
-
Day CP, James OF: Steatohepatitis: a tale of two 'hits'? Gastroenterology 1998;114:842-845.
-
(1998)
Gastroenterology
, vol.114
, pp. 842-845
-
-
Day, C.P.1
James, O.F.2
-
36
-
-
0033565109
-
Mechanisms of alcohol-induced hepatotoxicity: Studies in rats
-
Thurman RG, Bradford BU, Iimuro Y, Frankenberg MV, Knecht KT, Connor HD, Adachi Y, Wall C, Arteel GE, Raleigh JA, Forman DT, Mason RP: Mechanisms of alcohol-induced hepatotoxicity: studies in rats. Front Biosci 1999;4:e42-e46.
-
(1999)
Front Biosci
, vol.4
-
-
Thurman, R.G.1
Bradford, B.U.2
Iimuro, Y.3
Frankenberg, M.V.4
Knecht, K.T.5
Connor, H.D.6
Adachi, Y.7
Wall, C.8
Arteel, G.E.9
Raleigh, J.A.10
Forman, D.T.11
Mason, R.P.12
-
37
-
-
0026078067
-
Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: Reevaluation with an improved chromogenic assay
-
Fukui H, Brauner B, Bode JC, Bode C: Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. J Hepatol 1991;12:162-169.
-
(1991)
J Hepatol
, vol.12
, pp. 162-169
-
-
Fukui, H.1
Brauner, B.2
Bode, J.C.3
Bode, C.4
-
38
-
-
0032185432
-
II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin
-
Thurman RG: II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am J Physiol 1998;275:G605-G611.
-
(1998)
Am J Physiol
, vol.275
-
-
Thurman, R.G.1
-
39
-
-
0028796860
-
Antibiotics prevent liver injury in rats following long-term exposure to ethanol
-
Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG: Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995;108:218-224.
-
(1995)
Gastroenterology
, vol.108
, pp. 218-224
-
-
Adachi, Y.1
Moore, L.E.2
Bradford, B.U.3
Gao, W.4
Thurman, R.G.5
-
40
-
-
0028220726
-
Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease)
-
Nanji AA, Khettry U, Sadrzadeh SM: Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease). Proc Soc Exp Biol Med 1994;205:243-247.
-
(1994)
Proc Soc Exp Biol Med
, vol.205
, pp. 243-247
-
-
Nanji, A.A.1
Khettry, U.2
Sadrzadeh, S.M.3
-
41
-
-
0037087374
-
Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice
-
Uesugi T, Froh M, Arteel GE, Bradford BU, Wheeler MD, Gabele E, Isayama F, Thurman RG: Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice. J Immunol 2002;168:2963-2969.
-
(2002)
J Immunol
, vol.168
, pp. 2963-2969
-
-
Uesugi, T.1
Froh, M.2
Arteel, G.E.3
Bradford, B.U.4
Wheeler, M.D.5
Gabele, E.6
Isayama, F.7
Thurman, R.G.8
-
42
-
-
0035313376
-
Reduced early alcohol-induced liver injury in CD14-deficient mice
-
Yin M, Bradford BU, Wheeler MD, Uesugi T, Froh M, Goyert SM, Thurman RG: Reduced early alcohol-induced liver injury in CD14-deficient mice. J Immunol 2001;166:4737-4742.
-
(2001)
J Immunol
, vol.166
, pp. 4737-4742
-
-
Yin, M.1
Bradford, B.U.2
Wheeler, M.D.3
Uesugi, T.4
Froh, M.5
Goyert, S.M.6
Thurman, R.G.7
-
43
-
-
0034950477
-
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
-
Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG: Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 2001;34:101-108.
-
(2001)
Hepatology
, vol.34
, pp. 101-108
-
-
Uesugi, T.1
Froh, M.2
Arteel, G.E.3
Bradford, B.U.4
Thurman, R.G.5
-
45
-
-
0024587645
-
Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
-
McClain CJ, Cohen DA: Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 1989;9:349-351.
-
(1989)
Hepatology
, vol.9
, pp. 349-351
-
-
McClain, C.J.1
Cohen, D.A.2
-
46
-
-
0030716183
-
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
-
Iimuro Y, Gallucci RM, Luster MI, Kono H, Thurman RG: Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997;26:1530-1537.
-
(1997)
Hepatology
, vol.26
, pp. 1530-1537
-
-
Iimuro, Y.1
Gallucci, R.M.2
Luster, M.I.3
Kono, H.4
Thurman, R.G.5
-
47
-
-
0032835529
-
Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice
-
Yin M, Wheeler MD, Kono H, Bradford BU, Gallucci RM, Luster MI, Thurman RG: Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology 1999;117:942-952.
-
(1999)
Gastroenterology
, vol.117
, pp. 942-952
-
-
Yin, M.1
Wheeler, M.D.2
Kono, H.3
Bradford, B.U.4
Gallucci, R.M.5
Luster, M.I.6
Thurman, R.G.7
-
48
-
-
0036307759
-
Thalidomide prevents alcoholic liver injury in rats through suppression of Kupffer cell sensitization and TNF-alpha production
-
Enomoto N, Takei Y, Hirose M, Ikejima K, Miwa H, Kitamura T, Sato N: Thalidomide prevents alcoholic liver injury in rats through suppression of Kupffer cell sensitization and TNF-alpha production. Gastroenterology 2002;123:291-300.
-
(2002)
Gastroenterology
, vol.123
, pp. 291-300
-
-
Enomoto, N.1
Takei, Y.2
Hirose, M.3
Ikejima, K.4
Miwa, H.5
Kitamura, T.6
Sato, N.7
-
49
-
-
0025363385
-
Increased plasma tumor necrosis factor in severe alcoholic hepatitis
-
Bird GL, Sheron N, Goka AK, Alexander GJ, Williams RS: Increased plasma tumor necrosis factor in severe alcoholic hepatitis. Ann Intern Med 1990;112:917-920.
-
(1990)
Ann Intern Med
, vol.112
, pp. 917-920
-
-
Bird, G.L.1
Sheron, N.2
Goka, A.K.3
Alexander, G.J.4
Williams, R.S.5
-
50
-
-
0025278936
-
Plasma tumor necrosis factor alpha predicts decreased long-term survival in severe alcoholic hepatitis
-
Felver ME, Mezey E, McGuire M, Mitchell MC, Herlong HF, Veech GA, Veech RL: Plasma tumor necrosis factor alpha predicts decreased long-term survival in severe alcoholic hepatitis. Alcohol Clin Exp Res 1990;14:255-259.
-
(1990)
Alcohol Clin Exp Res
, vol.14
, pp. 255-259
-
-
Felver, M.E.1
Mezey, E.2
McGuire, M.3
Mitchell, M.C.4
Herlong, H.F.5
Veech, G.A.6
Veech, R.L.7
-
51
-
-
0034465251
-
Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: A double-blind, placebo-controlled trial
-
Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O: Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology 2000;119:1637-1648.
-
(2000)
Gastroenterology
, vol.119
, pp. 1637-1648
-
-
Akriviadis, E.1
Botla, R.2
Briggs, W.3
Han, S.4
Reynolds, T.5
Shakil, O.6
-
52
-
-
0037386110
-
Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis
-
Tilg H, Jalan R, Kaser A, Davies NA, Offner FA, Hodges SJ, Ludwiczek O, Shawcross D, Zoller H, Alisa A, Mookerjee RP, Graziadei I, Datz C, Trauner M, Schuppan D, Obrist P, Vogel W, Williams R: Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis. J Hepatol 2003;38:419-425.
-
(2003)
J Hepatol
, vol.38
, pp. 419-425
-
-
Tilg, H.1
Jalan, R.2
Kaser, A.3
Davies, N.A.4
Offner, F.A.5
Hodges, S.J.6
Ludwiczek, O.7
Shawcross, D.8
Zoller, H.9
Alisa, A.10
Mookerjee, R.P.11
Graziadei, I.12
Datz, C.13
Trauner, M.14
Schuppan, D.15
Obrist, P.16
Vogel, W.17
Williams, R.18
-
53
-
-
2342502025
-
A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis
-
Naveau S, Chollet-Martin S, Dharancy S, Mathurin P, Jouet P, Piquet MA, Davion T, Oberti F, Broet P, Emilie D: A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis. Hepatology 2004;39:1390-1397.
-
(2004)
Hepatology
, vol.39
, pp. 1390-1397
-
-
Naveau, S.1
Chollet-Martin, S.2
Dharancy, S.3
Mathurin, P.4
Jouet, P.5
Piquet, M.A.6
Davion, T.7
Oberti, F.8
Broet, P.9
Emilie, D.10
-
54
-
-
16544383147
-
Alcohol, oxidative stress, and free radical damage
-
Wu D, Cederbaum AI: Alcohol, oxidative stress, and free radical damage. Alcohol Res Health 2003;27:277-284.
-
(2003)
Alcohol Res Health
, vol.27
, pp. 277-284
-
-
Wu, D.1
Cederbaum, A.I.2
-
55
-
-
0037087202
-
Role of mitochondria in alcoholic liver injury
-
Adachi M, Ishii H: Role of mitochondria in alcoholic liver injury. Free Radic Biol Med 2002;32:487-491.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 487-491
-
-
Adachi, M.1
Ishii, H.2
-
56
-
-
1342323673
-
Oxidative stress, toxicology, and pharmacology of CYP2E1
-
Caro AA, Cederbaum AI: Oxidative stress, toxicology, and pharmacology of CYP2E1. Annu Rev Pharmacol Toxicol 2004;44:27-42.
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 27-42
-
-
Caro, A.A.1
Cederbaum, A.I.2
-
57
-
-
0037371816
-
Oxidants and antioxidants in alcohol-induced liver disease
-
Arteel GE: Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003;124:778-790.
-
(2003)
Gastroenterology
, vol.124
, pp. 778-790
-
-
Arteel, G.E.1
-
58
-
-
0033802236
-
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease
-
Kono H, Rusyn I, Yin M, Gabele E, Yamashina S, Dikalova A, Kadiiska MB, Connor HD, Mason RP, Segal BH, Bradford BU, Holland SM, Thurman RG: NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest 2000;106:867-872.
-
(2000)
J Clin Invest
, vol.106
, pp. 867-872
-
-
Kono, H.1
Rusyn, I.2
Yin, M.3
Gabele, E.4
Yamashina, S.5
Dikalova, A.6
Kadiiska, M.B.7
Connor, H.D.8
Mason, R.P.9
Segal, B.H.10
Bradford, B.U.11
Holland, S.M.12
Thurman, R.G.13
-
59
-
-
10744232492
-
Inducible nitric oxide synthase is required in alcohol-induced liver injury: Studies with knockout mice
-
McKim SE, Gabele E, Isayama F, Lambert JC, Tucker LM, Wheeler MD, Connor HD, Mason RP, Doll MA, Hein DW, Arteel GE: Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice. Gastroenterology 2003;125:1834-1844.
-
(2003)
Gastroenterology
, vol.125
, pp. 1834-1844
-
-
McKim, S.E.1
Gabele, E.2
Isayama, F.3
Lambert, J.C.4
Tucker, L.M.5
Wheeler, M.D.6
Connor, H.D.7
Mason, R.P.8
Doll, M.A.9
Hein, D.W.10
Arteel, G.E.11
-
60
-
-
0029125812
-
Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease
-
Niemela O, Parkkila S, Yla-Herttuala S, Villanueva J, Ruebner B, Halsted CH: Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease. Hepatology 1995;22:1208-1214.
-
(1995)
Hepatology
, vol.22
, pp. 1208-1214
-
-
Niemela, O.1
Parkkila, S.2
Yla-Herttuala, S.3
Villanueva, J.4
Ruebner, B.5
Halsted, C.H.6
-
61
-
-
0031011220
-
In situ detection of lipid peroxidation by-products in chronic liver diseases
-
Paradis V, Kollinger M, Fabre M, Holstege A, Poynard T, Bedossa P: In situ detection of lipid peroxidation by-products in chronic liver diseases. Hepatology 1997;26:135-142.
-
(1997)
Hepatology
, vol.26
, pp. 135-142
-
-
Paradis, V.1
Kollinger, M.2
Fabre, M.3
Holstege, A.4
Poynard, T.5
Bedossa, P.6
-
62
-
-
0025806044
-
Immunohistochemical demonstration of acetaldehyde-modified epitopes in human liver after alcohol consumption
-
Niemela O, Juvonen T, Parkkila S: Immunohistochemical demonstration of acetaldehyde-modified epitopes in human liver after alcohol consumption. J Clin Invest 1991;87:1367-1374.
-
(1991)
J Clin Invest
, vol.87
, pp. 1367-1374
-
-
Niemela, O.1
Juvonen, T.2
Parkkila, S.3
-
63
-
-
0028125857
-
Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: Localization and association with progression of liver fibrosis
-
Holstege A, Bedossa P, Poynard T, Kollinger M, Chaput JC, Houglum K, Chojkier M: Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: localization and association with progression of liver fibrosis. Hepatology 1994;19:367-374.
-
(1994)
Hepatology
, vol.19
, pp. 367-374
-
-
Holstege, A.1
Bedossa, P.2
Poynard, T.3
Kollinger, M.4
Chaput, J.C.5
Houglum, K.6
Chojkier, M.7
-
64
-
-
0010562619
-
Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts
-
USA
-
Israel Y, Hurwitz E, Niemela O, Arnon R: Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts. Proc Natl Acad Sci USA 1986;83:7923-7927.
-
(1986)
Proc Natl Acad Sci
, vol.83
, pp. 7923-7927
-
-
Israel, Y.1
Hurwitz, E.2
Niemela, O.3
Arnon, R.4
-
65
-
-
20644453966
-
Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: Relationship to liver disease severity and alcohol consumption
-
Viitala K, Israel Y, Blake JE, Niemela O: Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption. Hepatology 1997;25:1418-1424.
-
(1997)
Hepatology
, vol.25
, pp. 1418-1424
-
-
Viitala, K.1
Israel, Y.2
Blake, J.E.3
Niemela, O.4
-
66
-
-
0033861032
-
Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers
-
Viitala K, Makkonen K, Israel Y, Lehtimaki T, Jaakkola O, Koivula T, Blake JE, Niemela O: Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers. Alcohol Clin Exp Res 2000;24:1103-1109.
-
(2000)
Alcohol Clin Exp Res
, vol.24
, pp. 1103-1109
-
-
Viitala, K.1
Makkonen, K.2
Israel, Y.3
Lehtimaki, T.4
Jaakkola, O.5
Koivula, T.6
Blake, J.E.7
Niemela, O.8
-
67
-
-
0347334429
-
Obesity, adiponectin and vascular inflammatory disease
-
Ouchi N, Kihara S, Funahashi T, Matsuzawa Y, Walsh K: Obesity, adiponectin and vascular inflammatory disease. Curr Opin Lipidol 2003;14:561-566.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 561-566
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
Matsuzawa, Y.4
Walsh, K.5
-
69
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
-
Maeda N, Shimomura I, Kishida K, Nishizawa H, Matsuda M, Nagaretani H, Furuyama N, Kondo H, Takahashi M, Arita Y, Komuro R, Ouchi N, Kihara S, Tochino Y, Okutomi K, Horie M, Takeda S, Aoyama T, Funahashi T, Matsuzawa Y: Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 2002;8:731-737.
-
(2002)
Nat Med
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
Nishizawa, H.4
Matsuda, M.5
Nagaretani, H.6
Furuyama, N.7
Kondo, H.8
Takahashi, M.9
Arita, Y.10
Komuro, R.11
Ouchi, N.12
Kihara, S.13
Tochino, Y.14
Okutomi, K.15
Horie, M.16
Takeda, S.17
Aoyama, T.18
Funahashi, T.19
Matsuzawa, Y.20
more..
-
70
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ: The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003;112:91-100.
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
71
-
-
0033853732
-
Fibrogenesis. I. New insights into hepatic stellate cell activation: The simple becomes complex
-
Eng FJ, Friedman SL: Fibrogenesis. I. New insights into hepatic stellate cell activation: the simple becomes complex. Am J Physiol Gastrointest Liver Physiol 2000;279:G7-G11.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Eng, F.J.1
Friedman, S.L.2
-
74
-
-
0034956559
-
The role of Smad3 in mediating mouse hepatic stellate cell activation
-
Schnabl B, Kweon YO, Frederick JP, Wang XF, Rippe RA, Brenner DA: The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology 2001;34:89-100.
-
(2001)
Hepatology
, vol.34
, pp. 89-100
-
-
Schnabl, B.1
Kweon, Y.O.2
Frederick, J.P.3
Wang, X.F.4
Rippe, R.A.5
Brenner, D.A.6
-
75
-
-
0032835657
-
CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
-
Nieto N, Friedman SL, Greenwel P, Cederbaum AI: CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. Hepatology 1999;30:987-996.
-
(1999)
Hepatology
, vol.30
, pp. 987-996
-
-
Nieto, N.1
Friedman, S.L.2
Greenwel, P.3
Cederbaum, A.I.4
-
76
-
-
0035145392
-
Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cells
-
Svegliati-Baroni G, Saccomanno S, van Goor H, Jansen P, Benedetti A, Moshage H: Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cells. Liver 2001;21:1-12.
-
(2001)
Liver
, vol.21
, pp. 1-12
-
-
Svegliati-Baroni, G.1
Saccomanno, S.2
Van Goor, H.3
Jansen, P.4
Benedetti, A.5
Moshage, H.6
-
77
-
-
0029026661
-
Cytokines and cellular crosstalk involved in the activation of fat-storing cells
-
Gressner AM: Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J Hepatol 1995;22(suppl):28-36.
-
(1995)
J Hepatol
, vol.22
, Issue.SUPPL.
, pp. 28-36
-
-
Gressner, A.M.1
-
78
-
-
0032836925
-
Activation of rat hepatic stellate cells leads to loss of glutathione S-transferases and their enzymatic activity against products of oxidative stress
-
Whalen R, Rockey DC, Friedman SL, Boyer TD: Activation of rat hepatic stellate cells leads to loss of glutathione S-transferases and their enzymatic activity against products of oxidative stress. Hepatology 1999;30:927-933.
-
(1999)
Hepatology
, vol.30
, pp. 927-933
-
-
Whalen, R.1
Rockey, D.C.2
Friedman, S.L.3
Boyer, T.D.4
-
79
-
-
12644298684
-
Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide
-
Casini A, Ceni E, Salzano R, Biondi P, Parola M, Galli A, Foschi M, Caligiuri A, Pinzani M, Surrenti C: Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide. Hepatology 1997;25:361-367.
-
(1997)
Hepatology
, vol.25
, pp. 361-367
-
-
Casini, A.1
Ceni, E.2
Salzano, R.3
Biondi, P.4
Parola, M.5
Galli, A.6
Foschi, M.7
Caligiuri, A.8
Pinzani, M.9
Surrenti, C.10
-
80
-
-
0025485813
-
Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes
-
Moshage H, Casini A, Lieber CS: Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes. Hepatology 1990;12:511-518.
-
(1990)
Hepatology
, vol.12
, pp. 511-518
-
-
Moshage, H.1
Casini, A.2
Lieber, C.S.3
-
81
-
-
0025752432
-
Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism
-
Casini A, Cunningham M, Rojkind M, Lieber CS: Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 1991;13:758-765.
-
(1991)
Hepatology
, vol.13
, pp. 758-765
-
-
Casini, A.1
Cunningham, M.2
Rojkind, M.3
Lieber, C.S.4
-
82
-
-
0023637142
-
Acetaldehyde increases collagen gene transcription in cultured human fibroblasts
-
Brenner DA, Chojkier M: Acetaldehyde increases collagen gene transcription in cultured human fibroblasts. J Biol Chem 1987;262:17690-17695.
-
(1987)
J Biol Chem
, vol.262
, pp. 17690-17695
-
-
Brenner, D.A.1
Chojkier, M.2
|