Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes

Hepatology

Volumn 33, Issue 4, 2001, Pages 776-782

  Rippin, S J ^a   Hagenbuch, B ^a   Meier, P J ^a   Stieger, B ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; BILE SALT EXPORT PUMP; CARRIER PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; SODIUM ION; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; BASOLATERAL MEMBRANE; BILE SECRETION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHOLESTASIS; CONTROLLED STUDY; IN VITRO STUDY; INTRAHEPATIC BILE DUCT; LIVER CELL CULTURE; LIVER SINUSOID; MALE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; RNA STABILITY; RNA TRANSCRIPTION;

EID: 0035088560     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2001.23433     Document Type: Article

References (44)

1. The secretory function of the liver: New aspects of hepatobiliary transport
2. Hepatic transport of bile salts
3. Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver
4. The sister of p-glycoprotein represents the canalicular bile salt export pump of mammalian liver
5. Hepatobiliary secretion of organic compounds: Molecular mechanisms of membrane transport
6. Molecular pathogenesis of cholestasis
7. +/bile acid cotransporter in extrahepatic cholestasis
8. Ethinyl estradiol cholestasis involves alterations in expression of liver sinusoidal transporters
9. +-independent organic anion transporting polypeptide (oatp-1) in rats with bile duct ligation
10. The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
11. Expression of the bile salt export pump is maintained after chronic cholestasis in the rat
12. Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver
13. Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats
14. Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells
15. Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
16. Glutathione S-conjugate transport in hepatocytes entering the cell cycle is preserved by a switch in expression from the apical MRP2 to the basolateral MRP1 transporting protein
17. Alterations of bile acid and bumetanide uptake during culturing of rat hepatocytes
18. +-taurocholate cotransport and its encoding mRNA in primary cultures of rat hepatocytes
19. High-yield preparation of isolated rat liver parenchymal cells. A biochemical and fine structural study
20. Identification and characterization of a basolateral dicarboxylate/cholate antiport system in rat hepatocytes
21. Polarized amino acid transport by an epithelial cell line of renal origin (LLC-PK1). The apical systems
22. Measurement of protein using bicinchoninic acid
23. A simple, rapid, and sensitive DNA assay procedure
24. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
25. +/bile acid cotransport system
26. +-independent organic anion transporter
27. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
28. Functional expression of the rat liver canalicular isoform of the multidrug resistance-associated protein
29. Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver
30. Hepatocellular transport of bile acids. Evidence for distinct subcellular localizations of electrogenic and ATP-dependent taurocholate transport in rat hepatocytes
31. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
32. A domain-specific marker for the hepatocyte plasma membrane: Localization of leucine aminopeptidase to the bile canalicular membrane
33. +/taurocholate cotransporting polypeptide in rat liver
34. Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells
35. Transport function and hepatocellular localization of Mrp6 in rat liver
36. Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes
37. Molecular regulation of hepatocellular transport systems in cholestasis
38. Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes
39. Regulation of bile salt export pump mRNA levels by dexamethasone and osmolarity in cultured rat heptocytes
40. Partial maintenance of taurocholate uptake by adult rat hepatocytes cultured in a collagen sandwich configuration
41. Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration
42. Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (r1st-1) in rat liver
43. Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonparenchymal cells
44. Liver stem cells: A two compartment system