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Volumn 184, Issue 1, 2000, Pages 27-36

Effects of pertussis toxin on extracellular signal-regulated kinase activation in hepatocytes by hormones and receptor-independent agents: Evidence suggesting a stimulatory role of G(i) proteins at a level distal to receptor coupling

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; CALCIMYCIN; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PROSTAGLANDIN F2; PROTEIN KINASE C; THAPSIGARGIN; VASOPRESSIN;

EID: 0034036352     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(200007)184:1<27::AID-JCP3>3.0.CO;2-Q     Document Type: Article
Times cited : (28)

References (85)
  • 1
    • 0030743279 scopus 로고    scopus 로고
    • Possible involvement of pertussis toxin-sensitive G protein in hepatocyte growth factor-induced signal transduction in cultured rat hepatocytes: Pertussis toxin treatment inhibits activation of phospholipid signaling, calcium oscillation, and mitogen-activated protein kinase
    • Adachi T, Nakashima S, Saji S, Nakamura T, Nozawa Y. 1997. Possible involvement of pertussis toxin-sensitive G protein in hepatocyte growth factor-induced signal transduction in cultured rat hepatocytes: pertussis toxin treatment inhibits activation of phospholipid signaling, calcium oscillation, and mitogen-activated protein kinase. Hepatology 26:295-300.
    • (1997) Hepatology , vol.26 , pp. 295-300
    • Adachi, T.1    Nakashima, S.2    Saji, S.3    Nakamura, T.4    Nozawa, Y.5
  • 6
    • 0027233448 scopus 로고
    • Signal transduction via the MAP kinases: Proceed at your own RSK
    • Blenis J. 1993. Signal transduction via the MAP kinases: proceed at your own RSK. Proc Natl Acad Sci USA 90:5889-5892.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5889-5892
    • Blenis, J.1
  • 7
    • 0000545827 scopus 로고
    • Regulatory mechanisms in hepatic regeneration
    • Milward-Sadler GH, Wright R, Arthur MJP, editors. London: W.B. Saunders
    • Bucher NLR, Strain AJ. 1992. Regulatory mechanisms in hepatic regeneration. In: Milward-Sadler GH, Wright R, Arthur MJP, editors. Wright's liver and biliary disease. Volume 11. London: W.B. Saunders, p 258-274.
    • (1992) Wright's Liver and Biliary Disease , vol.11 , pp. 258-274
    • Bucher, N.L.R.1    Strain, A.J.2
  • 9
    • 0029778746 scopus 로고    scopus 로고
    • Comparison of the subcellular distribution of G-proteins in hepatocytes in situ and in primary cultures
    • Cadrin M, McFarlane-Anderson N, Harper ME, Gaffield J, Begin-Heick N. 1996. Comparison of the subcellular distribution of G-proteins in hepatocytes in situ and in primary cultures. J Cell Biochem 62:334-341.
    • (1996) J Cell Biochem , vol.62 , pp. 334-341
    • Cadrin, M.1    McFarlane-Anderson, N.2    Harper, M.E.3    Gaffield, J.4    Begin-Heick, N.5
  • 10
    • 0032030621 scopus 로고    scopus 로고
    • Rethinking receptor-G protein-effector interactions
    • Chidiac P. 1998. Rethinking receptor-G protein-effector interactions. Biochem Pharmacol 55:549-556.
    • (1998) Biochem Pharmacol , vol.55 , pp. 549-556
    • Chidiac, P.1
  • 11
    • 0033538338 scopus 로고    scopus 로고
    • Regulation of ras · GTP loading and ras-raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester
    • Chiloeches A, Paterson HF, Marais R, Clerk A, Marshall CJ, Sugden PH. 1999. Regulation of ras · GTP loading and ras-raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester. J Biol Chem 274:19762-19770.
    • (1999) J Biol Chem , vol.274 , pp. 19762-19770
    • Chiloeches, A.1    Paterson, H.F.2    Marais, R.3    Clerk, A.4    Marshall, C.J.5    Sugden, P.H.6
  • 12
    • 0021321478 scopus 로고
    • Changes in hormone responsiveness and cyclic AMP metabolism in rat hepatocytes during primary culture and effects of supplementing the medium with insulin and dexamethasone
    • Christoffersen T, Refsnes M, Brønstad GO, Østby E, Huse J, Haffner F, Sand TE, Hunt NH, Sonne O. 1984. Changes in hormone responsiveness and cyclic AMP metabolism in rat hepatocytes during primary culture and effects of supplementing the medium with insulin and dexamethasone. Eur J Biochem 138:217-226.
    • (1984) Eur J Biochem , vol.138 , pp. 217-226
    • Christoffersen, T.1    Refsnes, M.2    Brønstad, G.O.3    Østby, E.4    Huse, J.5    Haffner, F.6    Sand, T.E.7    Hunt, N.H.8    Sonne, O.9
  • 13
    • 0009638576 scopus 로고    scopus 로고
    • Mechanisms of hepatocyte growth regulation by hormones and growth factors
    • Berry MN, Edwards AM, editors. Dordrecht: Kluwer Academic Publishers, (in press)
    • Christoffersen T, Thoresen GH, Dajani OF, Melien Ø, Guren T, Refsnes M, Sandnes D. 2000. Mechanisms of hepatocyte growth regulation by hormones and growth factors. In: Berry MN, Edwards AM, editors. The Hepatocyte Review. Dordrecht: Kluwer Academic Publishers, (in press).
    • (2000) The Hepatocyte Review
    • Christoffersen, T.1    Thoresen, G.H.2    Dajani, O.F.3    Melien, O.4    Guren, T.5    Refsnes, M.6    Sandnes, D.7
  • 19
    • 0033059888 scopus 로고    scopus 로고
    • Role of diacylglycerol (DAG) in hormonal induction of S phase in hepatocytes: The DAG-dependent protein kinase C pathway is not activated by epidermal growth factor (EGF), but is involved in mediating the enhancement of responsiveness to EGF by vasopressin, angiotensin II, and norepinephrine
    • Dajani OF, Sandnes D, Melien Ø, Rezvani F, Nilssen LS, Thoresen GH, Christoffersen T. 1999. Role of diacylglycerol (DAG) in hormonal induction of S phase in hepatocytes: the DAG-dependent protein kinase C pathway is not activated by epidermal growth factor (EGF), but is involved in mediating the enhancement of responsiveness to EGF by vasopressin, angiotensin II, and norepinephrine. J Cell Physiol 180:203-214.
    • (1999) J Cell Physiol , vol.180 , pp. 203-214
    • Dajani, O.F.1    Sandnes, D.2    Melien, O.3    Rezvani, F.4    Nilssen, L.S.5    Thoresen, G.H.6    Christoffersen, T.7
  • 20
  • 21
    • 0032573386 scopus 로고    scopus 로고
    • Expression of an oncogenic mutant Gαi2 activates Ras in Rat-1 fibroblast cells
    • Edamatsu H, Kaziro Y, Itoh H. 1998. Expression of an oncogenic mutant Gαi2 activates Ras in Rat-1 fibroblast cells. FEBS Lett 440:231-234.
    • (1998) FEBS Lett , vol.440 , pp. 231-234
    • Edamatsu, H.1    Kaziro, Y.2    Itoh, H.3
  • 22
    • 0029936331 scopus 로고    scopus 로고
    • Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins
    • Exton JH. 1996. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36:481-509.
    • (1996) Annu Rev Pharmacol Toxicol , vol.36 , pp. 481-509
    • Exton, J.H.1
  • 23
  • 24
    • 0028176297 scopus 로고
    • cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure M, Voyno-Yasenetskaya TA, Bourne HR. 1994. cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J Biol Chem 269: 7851-7854.
    • (1994) J Biol Chem , vol.269 , pp. 7851-7854
    • Faure, M.1    Voyno-Yasenetskaya, T.A.2    Bourne, H.R.3
  • 25
    • 0027483677 scopus 로고
    • 1-Adrenergic action: Receptor subtypes, signal transduction and regulation
    • 1-Adrenergic action: receptor subtypes, signal transduction and regulation. Cell Signal 5:539-547.
    • (1993) Cell Signal , vol.5 , pp. 539-547
    • Garcia-Sainz, J.A.1
  • 26
    • 85045533874 scopus 로고    scopus 로고
    • Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes
    • Gines P, Xiaomeli L, Brown SES, Nakamura T, Guzelian PS, Heasley LE, Schrier RW, Nemenoff RA. 1996. Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes. Hepatology 23:1167-1173.
    • (1996) Hepatology , vol.23 , pp. 1167-1173
    • Gines, P.1    Xiaomeli, L.2    Brown, S.E.S.3    Nakamura, T.4    Guzelian, P.S.5    Heasley, L.E.6    Schrier, R.W.7    Nemenoff, R.A.8
  • 27
    • 0026640629 scopus 로고
    • MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts
    • Gupta SK, Gallego C, Johnson GL, Heasley LE. 1992. MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts. J Biol Chem 267:7987-7990.
    • (1992) J Biol Chem , vol.267 , pp. 7987-7990
    • Gupta, S.K.1    Gallego, C.2    Johnson, G.L.3    Heasley, L.E.4
  • 30
    • 17344362824 scopus 로고    scopus 로고
    • Cell growth control by G protein-coupled receptors: From signal transduction to signal integration
    • Gutkind JS. 1998. Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17:1331-1342.
    • (1998) Oncogene , vol.17 , pp. 1331-1342
    • Gutkind, J.S.1
  • 31
    • 0025282587 scopus 로고
    • 1-adrenergic receptor subtypes and formation of inositol phosphates in dispersed hepatocytes and renal cells
    • 1-adrenergic receptor subtypes and formation of inositol phosphates in dispersed hepatocytes and renal cells. Mol Pharmacol 37:903-910.
    • (1990) Mol Pharmacol , vol.37 , pp. 903-910
    • Han, C.D.1    Wilson, K.M.2    Minneman, K.P.3
  • 32
    • 0027077976 scopus 로고
    • Epigenetic activation of Gi-2 protein, the product of a putative protooncogene, mediates tumor promotion in vitro
    • Harbers M, Borowski P, Fanick W, Lengyel H, Buck F, Hinsch KD, Hilz H. 1992. Epigenetic activation of Gi-2 protein, the product of a putative protooncogene, mediates tumor promotion in vitro. Carcinogenesis 13:2403-2406.
    • (1992) Carcinogenesis , vol.13 , pp. 2403-2406
    • Harbers, M.1    Borowski, P.2    Fanick, W.3    Lengyel, H.4    Buck, F.5    Hinsch, K.D.6    Hilz, H.7
  • 33
    • 0033538342 scopus 로고    scopus 로고
    • i proteins use a novel βγ- and Ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes
    • i proteins use a novel βγ- and Ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes. J Biol Chem 274:19992-20001.
    • (1999) J Biol Chem , vol.274 , pp. 19992-20001
    • Hedin, K.E.1    Bell, M.P.2    Huntoon, C.J.3    Karnitz, L.M.4    McKean, D.J.5
  • 35
    • 0029988205 scopus 로고    scopus 로고
    • In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein
    • Hermouet S, Aznavoorian S, Spiegel AM. 1996. In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein. Cell Signal 8:159-166.
    • (1996) Cell Signal , vol.8 , pp. 159-166
    • Hermouet, S.1    Aznavoorian, S.2    Spiegel, A.M.3
  • 36
    • 0029134812 scopus 로고
    • α- and β-Adrenoceptors: From the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification
    • Hieble JP, Bondinell WE, Ruffolo RJ. 1995. α- and β-Adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification. J Med Chem 38:3415-3444.
    • (1995) J Med Chem , vol.38 , pp. 3415-3444
    • Hieble, J.P.1    Bondinell, W.E.2    Ruffolo, R.J.3
  • 37
    • 0019404985 scopus 로고
    • Alpha-adrenergic receptors in liver membranes: Delineation with subtype selective radioligands
    • Hoffman BB, Dukes DF, Lefkowitz RJ. 1981. Alpha-adrenergic receptors in liver membranes: delineation with subtype selective radioligands. Life Sci 28:265-272.
    • (1981) Life Sci , vol.28 , pp. 265-272
    • Hoffman, B.B.1    Dukes, D.F.2    Lefkowitz, R.J.3
  • 38
    • 0028868582 scopus 로고
    • 1B-adrenoceptors, pertussis toxin-sensitive G proteins, and protein kinase C
    • 1B-adrenoceptors, pertussis toxin-sensitive G proteins, and protein kinase C. Circulation 92:2259-2265.
    • (1995) Circulation , vol.92 , pp. 2259-2265
    • Hu, K.1    Nattel, S.2
  • 39
    • 0032589074 scopus 로고    scopus 로고
    • 1-adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: Role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase
    • 1-adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase. J Pharmacol Exp Ther 290:28-37.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 28-37
    • Hu, Z.W.1    Shi, X.Y.2    Lin, R.Z.3    Chen, J.4    Hoffman, B.B.5
  • 43
    • 0031900740 scopus 로고    scopus 로고
    • Signal transduction through MAP kinase cascades
    • Lewis TS, Shapiro PS, Ahn NG. 1998. Signal transduction through MAP kinase cascades. Adv Cancer Res 74:49-139.
    • (1998) Adv Cancer Res , vol.74 , pp. 49-139
    • Lewis, T.S.1    Shapiro, P.S.2    Ahn, N.G.3
  • 44
    • 0025800018 scopus 로고
    • The epidermal growth factor receptor is coupled to a pertussis toxin-sensitive guanine nucleotide regulatory protein in rat hepatocytes
    • Liang M, Garrison JC. 1991. The epidermal growth factor receptor is coupled to a pertussis toxin-sensitive guanine nucleotide regulatory protein in rat hepatocytes. J Biol Chem 266:13342-13349.
    • (1991) J Biol Chem , vol.266 , pp. 13342-13349
    • Liang, M.1    Garrison, J.C.2
  • 45
    • 0031959819 scopus 로고    scopus 로고
    • Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi-proteins) in experimental hepatocellular carcinoma
    • McKillop IH, Wu Y, Cahill PA, Sitzmann JV. 1998. Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi-proteins) in experimental hepatocellular carcinoma. J Cell Physiol 175:295-304.
    • (1998) J Cell Physiol , vol.175 , pp. 295-304
    • McKillop, I.H.1    Wu, Y.2    Cahill, P.A.3    Sitzmann, J.V.4
  • 48
    • 0031971122 scopus 로고    scopus 로고
    • 2α in hepatocytes is sustained, and like the effect of epidermal growth factor, mediated through pertussis toxin-sensitive mechanisms
    • 2α in hepatocytes is sustained, and like the effect of epidermal growth factor, mediated through pertussis toxin-sensitive mechanisms. J Cell Physiol 175:348-358.
    • (1998) J Cell Physiol , vol.175 , pp. 348-358
    • Melien, O.1    Thoresen, G.H.2    Sandnes, D.3    Østby, E.4    Christoffersen, T.5
  • 50
    • 0025122144 scopus 로고
    • Liver regeneration: Molecular mechanisms of growth control
    • Michalopoulos GK. 1990. Liver regeneration: molecular mechanisms of growth control. FASEB J 4:176-187.
    • (1990) FASEB J , vol.4 , pp. 176-187
    • Michalopoulos, G.K.1
  • 51
    • 0029861096 scopus 로고    scopus 로고
    • G-protein α subunit Giα2 mediates erythropoietin signal transduction in human erythroid precursors
    • Miller BA, Bell L, Hansen CA, Robishaw JD, Linder ME, Cheung JY. 1996. G-protein α subunit Giα2 mediates erythropoietin signal transduction in human erythroid precursors. J Clin Invest 98:1728-1736.
    • (1996) J Clin Invest , vol.98 , pp. 1728-1736
    • Miller, B.A.1    Bell, L.2    Hansen, C.A.3    Robishaw, J.D.4    Linder, M.E.5    Cheung, J.Y.6
  • 53
    • 0021082206 scopus 로고
    • Studies on the mechanism of inhibition of hepatic cAMP accumulation by vasopressin
    • Morgan NG, Shipp CC, Exton JH. 1983. Studies on the mechanism of inhibition of hepatic cAMP accumulation by vasopressin. FEBS Lett 163:277-281.
    • (1983) FEBS Lett , vol.163 , pp. 277-281
    • Morgan, N.G.1    Shipp, C.C.2    Exton, J.H.3
  • 55
    • 0020526730 scopus 로고
    • Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes
    • Murayama T, Ui M. 1983. Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes. J Biol Chem 258:3319-3326.
    • (1983) J Biol Chem , vol.258 , pp. 3319-3326
    • Murayama, T.1    Ui, M.2
  • 56
    • 0030600131 scopus 로고    scopus 로고
    • Potential roles of heterotrimeric G proteins of the endomembrane system
    • Nürnberg B, Ahnert-Hilger G. 1996. Potential roles of heterotrimeric G proteins of the endomembrane system. FEBS Lett 389:61-65.
    • (1996) FEBS Lett , vol.389 , pp. 61-65
    • Nürnberg, B.1    Ahnert-Hilger, G.2
  • 59
    • 0022273623 scopus 로고
    • i in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes
    • i in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes. J Biol Chem 260:16200-16209.
    • (1985) J Biol Chem , vol.260 , pp. 16200-16209
    • Pobiner, B.F.1    Hewlett, E.L.2    Garrison, J.C.3
  • 60
    • 0028999448 scopus 로고
    • Role of heterotrimeric G-proteins in epidermal growth factor signalling
    • Ramirez I, Tebar F, Grau M, Soley M. 1995. Role of heterotrimeric G-proteins in epidermal growth factor signalling. Cell Signal 7:303-311.
    • (1995) Cell Signal , vol.7 , pp. 303-311
    • Ramirez, I.1    Tebar, F.2    Grau, M.3    Soley, M.4
  • 61
    • 0031001608 scopus 로고    scopus 로고
    • Does subunit dissociation necessarily accompany the activation of all heterotrimeric G proteins?
    • Rebois RV, Warner DR, Basi NS. 1997. Does subunit dissociation necessarily accompany the activation of all heterotrimeric G proteins? Cell Signal 9:141-151.
    • (1997) Cell Signal , vol.9 , pp. 141-151
    • Rebois, R.V.1    Warner, D.R.2    Basi, N.S.3
  • 62
    • 0021056014 scopus 로고
    • Mechanisms for the emergence of catecholamine-sensitive adenylate cyclase and β-adrenergic receptors in cultured hepatocytes. Dependence on protein and RNA synthesis and suppression by isoproterenol
    • Refsnes M, Sandnes D, Melien Ø, Sand TE, Jacobsen S, Christoffersen T. 1983. Mechanisms for the emergence of catecholamine-sensitive adenylate cyclase and β-adrenergic receptors in cultured hepatocytes. Dependence on protein and RNA synthesis and suppression by isoproterenol. FEBS Lett 164:291-298.
    • (1983) FEBS Lett , vol.164 , pp. 291-298
    • Refsnes, M.1    Sandnes, D.2    Melien, O.3    Sand, T.E.4    Jacobsen, S.5    Christoffersen, T.6
  • 64
    • 0030925608 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase in freshly isolated rat hepatocytes by both a calcium- and a protein kinase C-dependent pathway
    • Romanelli A, van de Werve G. 1997. Activation of mitogen-activated protein kinase in freshly isolated rat hepatocytes by both a calcium- and a protein kinase C-dependent pathway. Metabolism 46:548-555.
    • (1997) Metabolism , vol.46 , pp. 548-555
    • Romanelli, A.1    Van De Werve, G.2
  • 67
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen PO, 1976. Preparation of isolated rat liver cells. Methods Cell Biol 13:29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 69
    • 0030610945 scopus 로고    scopus 로고
    • 1A vasopressin antagonist and its use in characterizing receptor/G protein interactions
    • 1A vasopressin antagonist and its use in characterizing receptor/G protein interactions. Mol Pharmacol 51:217-224.
    • (1997) Mol Pharmacol , vol.51 , pp. 217-224
    • Strakova, Z.1    Kumar, A.2    Watson, A.J.3    Soloff, M.S.4
  • 70
    • 0023766145 scopus 로고
    • Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
    • Sturgill TW, Ray LB, Erikson E, Mailer JL. 1988. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334:715-718.
    • (1988) Nature , vol.334 , pp. 715-718
    • Sturgill, T.W.1    Ray, L.B.2    Erikson, E.3    Mailer, J.L.4
  • 71
    • 0030747146 scopus 로고    scopus 로고
    • Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors
    • Sugden PH, Clerk A. 1997. Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors. Cell Signal 9:337-351.
    • (1997) Cell Signal , vol.9 , pp. 337-351
    • Sugden, P.H.1    Clerk, A.2
  • 72
    • 0026669425 scopus 로고
    • A GTP-binding protein in rat liver nuclei serving as the specific substrate of pertussis toxin-catalyzed ADP-ribosylation
    • Takei Y, Kurosu H, Takahashi K, Katada T. 1992. A GTP-binding protein in rat liver nuclei serving as the specific substrate of pertussis toxin-catalyzed ADP-ribosylation. J Biol Chem 267:5085-5089.
    • (1992) J Biol Chem , vol.267 , pp. 5085-5089
    • Takei, Y.1    Kurosu, H.2    Takahashi, K.3    Katada, T.4
  • 73
    • 0028204526 scopus 로고
    • Possible involvement of a pertussis toxin-sensitive GTP-binding protein in protein transport into nuclei isolated from rat liver
    • Takei Y, Takahashi K, Kanaho Y, Katada T. 1994. Possible involvement of a pertussis toxin-sensitive GTP-binding protein in protein transport into nuclei isolated from rat liver. J Biochem (Tokyo) 115:578-583.
    • (1994) J Biochem (Tokyo) , vol.115 , pp. 578-583
    • Takei, Y.1    Takahashi, K.2    Kanaho, Y.3    Katada, T.4
  • 75
    • 0031937366 scopus 로고    scopus 로고
    • Response to transforming growth factor alfa (TGFα) and epidermal growth factor (EGF) in hepatocytes: Lower EGF receptor affinity of TGFa is associated with more sustained activation of p42/p44 mitogen-activated protein kinase and greater efficacy in stimulation of DNA synthesis
    • Thoresen GH, Guren TK, Sandnes D, Peak M, Agius L, Christoffersen T. 1998. Response to transforming growth factor alfa (TGFα) and epidermal growth factor (EGF) in hepatocytes: lower EGF receptor affinity of TGFa is associated with more sustained activation of p42/p44 mitogen-activated protein kinase and greater efficacy in stimulation of DNA synthesis. J Cell Physiol 175:10-18.
    • (1998) J Cell Physiol , vol.175 , pp. 10-18
    • Thoresen, G.H.1    Guren, T.K.2    Sandnes, D.3    Peak, M.4    Agius, L.5    Christoffersen, T.6
  • 76
    • 0025259990 scopus 로고
    • Possible interaction of α1-adrenergic receptor with pertussis-toxin-sensitive guanine-nucleotide-binding regulatory proteins (G proteins) responsible for phospholipase C activation in rat liver plasma membranes
    • Tohkin M, Yagami T, Katada T, Matsubara T. 1990. Possible interaction of α1-adrenergic receptor with pertussis-toxin-sensitive guanine-nucleotide-binding regulatory proteins (G proteins) responsible for phospholipase C activation in rat liver plasma membranes. Eur J Biochem 194:81-87.
    • (1990) Eur J Biochem , vol.194 , pp. 81-87
    • Tohkin, M.1    Yagami, T.2    Katada, T.3    Matsubara, T.4
  • 80
    • 0029664963 scopus 로고    scopus 로고
    • Gα12 and Gα13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells
    • Voyno-Yasenetskaya TA, Faure MP, Ahn NG, Bourne HR. 1996. Gα12 and Gα13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells. J Biol Chem 271:21081-21087.
    • (1996) J Biol Chem , vol.271 , pp. 21081-21087
    • Voyno-Yasenetskaya, T.A.1    Faure, M.P.2    Ahn, N.G.3    Bourne, H.R.4
  • 81
    • 0030091643 scopus 로고    scopus 로고
    • Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins
    • Wickramasinghe NS, Jo H, McDonald JM, Hardy RW. 1996. Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins. Am J Pathol 148:987-995.
    • (1996) Am J Pathol , vol.148 , pp. 987-995
    • Wickramasinghe, N.S.1    Jo, H.2    McDonald, J.M.3    Hardy, R.W.4
  • 82
    • 0029824649 scopus 로고    scopus 로고
    • Pharmacology of pertussis toxin B-oligomer
    • Wong WAS, Rosoff PM. 1996. Pharmacology of pertussis toxin B-oligomer. Can J Physiol Pharmacol 74:559-564.
    • (1996) Can J Physiol Pharmacol , vol.74 , pp. 559-564
    • Wong, W.A.S.1    Rosoff, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.