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Volumn 15, Issue 8, 2001, Pages 546-550
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High-throughput analysis in drug discovery: Application of liquid chromatography/ion-trap mass spectrometry for simultaneous cassette analysis of α-1a antagonists and their metabolites in mouse plasma
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Author keywords
[No Author keywords available]
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Indexed keywords
BIOMOLECULES;
DRUG PRODUCTS;
LIQUID CHROMATOGRAPHY;
MAMMALS;
MASS SPECTROMETRY;
SCREENING;
'CURRENT;
CASSETTE ANALYSIS;
DRUG DISCOVERY APPLICATIONS;
HIGH-THROUGHPUT ANALYSIS;
IN-VITRO;
IN-VIVO;
LIQUID CHROMATOGRAPHY-ION TRAP MASS SPECTROMETRY;
MICE PLASMA;
PLASMA SAMPLES;
VITRO EXPERIMENTS;
METABOLITES;
ADRENERGIC ALPHA ANTAGONISTS;
ALPHA 1 ADRENERGIC RECEPTOR;
ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT;
ALPHA 1A ADRENERGIC RECEPTOR;
ALPHA 1A ADRENERGIC RECEPTOR ANTAGONIST;
ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT;
GI 198579;
GI 228035;
GI 230016;
GI 231818;
GI 239270;
RECEPTORS, ADRENERGIC, ALPHA 1;
UNCLASSIFIED DRUG;
ANIMAL;
ANIMAL CELL;
ANIMAL TISSUE;
ARTICLE;
CELL FRACTIONATION;
DEMETHYLATION;
DOSE RESPONSE;
DRUG METABOLISM;
DRUG SCREENING;
DRUG STABILITY;
DRUG STRUCTURE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYDROXYLATION;
LIQUID CHROMATOGRAPHY;
LIVER;
MALE;
MASS SPECTROMETRY;
MOUSE;
NONHUMAN;
QUANTITATIVE DIAGNOSIS;
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EID: 0035032944
PISSN: 09514198
EISSN: None
Source Type: Journal
DOI: 10.1002/rcm.266 Document Type: Article |
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Times cited : (24)
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References (16)
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