HIV-1 infection of langerhans cells in a reconstructed vaginal mucosa

Journal of Infectious Diseases

Volumn 190, Issue 2, 2004, Pages 227-235

  Sivard, Peggy ^a   Berlier, Willy ^a   Picard, Bertrand ^b   Sabido, Odile ^a   Genin, Christian ^a   Misery, Laurent ^a,c,d  

^a UNIVERSITÉ JEAN MONNET   (France)

^b BREST UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^d CHU MORVAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CHEMOKINE; RANTES; RNA DIRECTED DNA POLYMERASE INHIBITOR; STROMAL CELL DERIVED FACTOR 1; VIRUS DNA; ZIDOVUDINE;

ARTICLE; BLOOD CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG INHIBITION; FEMALE; FEMALE GENITAL SYSTEM; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; LANGERHANS CELL; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN SECRETION; T LYMPHOCYTE; UMBILICAL CORD BLOOD; VAGINA MUCOSA; VAGINA RECONSTRUCTION; VIRUS STRAIN;

ANTI-HIV AGENTS; ANTIGENS, CD34; ANTIVIRAL AGENTS; CHEMOKINES, CXC; COCULTURE TECHNIQUES; CULTURE TECHNIQUES; DNA, VIRAL; FEMALE; HEMATOPOIETIC STEM CELLS; HIV-1; HUMANS; LANGERHANS CELLS; LEUKOCYTES, MONONUCLEAR; MUCOUS MEMBRANE; PROVIRUSES; RANTES; RECEPTORS, CCR5; RECEPTORS, CXCR4; RECEPTORS, HIV; VAGINA; ZIDOVUDINE;

EID: 3242689431     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/421704     Document Type: Article

References (60)

1. Fauci AS. The AIDS epidemic - considerations for the 21st century. N Engl J Med 1999; 341:1046-50.
2. Gupta P, Mellors J, Kingsley L, et al. High viral load in semen of human immunodeficiency virus type 1-infected men at all stages of disease and its reduction by therapy with protease and nonnucleoside reverse transcriptase inhibitors. J Virol 1997; 71:6271-5.
3. Kahn JO, Walker BD. Acute human immunodeficiency virus type 1 infection. N Engl J Med 1998; 339:33-9.
4. Royce RA, Sena A, Cates W Jr, Cohen MS. Sexual transmission of HIV. N Engl J Med 1997; 336:1072-8.
5. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392:245-52.
6. de Fraissinette A, Schmitt D, Thivolet J. Langerhans cells of human mucosa. J Dermatol 1989; 16:255-62.
7. Cameron P, Pope M, Granelli-Piperno A, Steinman RM. Dendritic cells and the replication of HIV-1. J Leukoc Biol 1996; 59:158-71.
8. Knight SC, Patterson S. Bone marrow-derived dendritic cells, infection with human immunodeficiency virus, and immunopathology. Annu Rev Immunol 1997; 15:593-615.
9. Miller CJ, Hu J. T cell-tropic simian immunodeficiency virus (SIV) and simian-human immunodeficiency viruses are readily transmitted by vaginal inoculation of rhesus macaques, and Langerhans' cells of the female genital tract are infected with SIV. J Infect Dis 1999; 179(Suppl 3):S413-7.
10. Ayehunie S, Groves RW, Bruzzese AM, Ruprecht RM, Kupper TS, Langhoff E. Acutely infected Langerhans cells are more efficient than T cells in disseminating HIV type 1 to activated T cells following a short cell-cell contact. AIDS Res Hum Retroviruses 1995; 11:877-84.
11. + hematopoietic progenitor cells is primarily determined by their maturation stage. Blood 1999; 93:3866-75.
12. + progenitor-derived dendritic/Langerhans cells at different stages of their differentiation in the presence of GM-CSF/TNF α. Res Virol 1996; 147:89-95.
13. Tchou I, Misery L, Sabido O, et al. Functional HIV CXCR4 coreceptor on human epithelial Langerhans cells and infection by HIV strain X4. J Leukoc Biol 2001; 70:1-9.
14. Zaitseva M, Blauvelt A, Lee S, et al. Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection. Nat Med 1997; 3:1369-75.
15. Zambruno G, Mori L, Marconi A, et al. Detection of HIV-1 in epidermal Langerhans cells of HIV-infected patients using the polymerase chain reaction. J Invest Dermatol 1991; 96:979-82.
16. + T cells. J Exp Med 1995; 182:2045-56.
17. Zambruno G, Giannetti A, Bertazzoni U, Girolomoni G. Langerhans cells and HIV infection. Immunol Today 1995; 16:520-4.
18. Sivard P, Dezutter-Dambuyant C, Kanitakis J, et al. In vitro reconstructed mucosa integrating Langerhans cells. Exp Dermatol 2003; 12:346-55.
19. Rheinwald J, Green H. Serial cultivation of stains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 1975; 6:331-44.
20. + hematopoietic progenitor cells. Blood 1990; 75:2292-8.
21. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF + TNF α. J Exp Med 1996; 184:695-706.
22. + hematopoietic progenitor cells. Blood 1996; 87:2376-85.
23. + hematopoietic progenitor cells. Blood 1996; 87:1292-302.
24. + progenitors. J Leukoc Biol 1999; 66:781-91.
25. + hemopoietic progenitors. J Immunol 1996; 157:1499-507.
26. Strobl H, Bello-Fernandez C, Riedl E, et al. flt3 ligand in cooperation with transforming growth factor-β1 potentiates in vitro development of Langerhans-type dendritic cells and allows single-cell dendritic cell cluster formation under serum-free conditions. Blood 1997; 90:1425-34.
27. Prunieras M, Regnier M, Schlotterer M. New procedure for culturing human epidermal cells on allogenic or xenogenic skin: preparation of recombined grafts. Ann Chir Plast 1979; 24:357-62.
28. Régnier M, Schweizer J, Michel S, Bailly C, Prunieras M. Expression of high molecular weight (67K) keratin in human keratinocytes cultured on dead de-epidermized dermis. Exp Cell Res 1986; 165:63-72.
29. Régnier M, Asselineau D, Lenoir MC. Human epidermis reconstructed on dermal substrates in vitro: an alternative to animals in skin pharmacology. Skin Pharmacol 1990; 3:70-85.
30. Valladeau J, Ravel O, Dezutter-Dambuyant C, et al. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 2000; 12:71-81.
31. Fantini J, Cook DG, Nathanson N, Spitalnik SL, Gonzalez-Scarano F. Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor. Proc Natl Acad Sci USA 1993; 90:2700-4.
32. Chu A, Eisinger M, Lee JS, Takezaki S, Kung PC, Edelson RL. Immunoelectron microscopic identification of Langerhans cells using a new antigenic marker. J Invest Dermatol 1982; 78:177-80.
33. Valladeau J, Ouvert-Frances V, Pin JJ, et al. The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface. Eur J Immunol 1999; 29:2695-704.
34. Valladeau J, Caux C, Lebecque S, Saeland S. Langerin: a new lectin specific for Langerhans cells induces the formation of Birbeck granules [in French]. Pathol Biol (Paris) 2001; 49:454-5.
35. Cocchia D, Michetti F, Donato R. Immunochemical and immunocytochemical localization of S-100 antigen in normal human skin. Nature 1981; 294:85-7.
36. Régnier M, Staquet M-J, Schmitt D, Schmidt R. Integration of Langerhans cells into a pigmented reconstructed human epidermis. J Invest Dermatol 1997; 109:510-2.
37. Hu J, Pope M, Brown C, O'Doherty U, Miller CJ. Immunophenotypic characterization of simian immunodeficiency virus-infected dendritic cells in cervix, vagina, and draining lymph nodes of rhesus monkeys. Lab Invest 1998; 78:435-51.
38. Hu J, Gardner MB, Miller CJ. Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells. J Virol 2000; 74:6087-95.
39. Kawamura T, Cohen SS, Borris DL, et al. Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants. J Exp Med 2000; 192:1491-500.
40. Canque B, Rosenzwajg M, Camus S, et al. The effect of in vitro human immunodeficiency virus infection on dendritic-cell differentiation and function. Blood 1996; 88:4215-28.
41. Blauvelt A, Glushakova S, Margolis LB. HIV-infected human Langerhans cells transmit infection to human lymphoid tissue ex vivo. AIDS 2000; 14:647-51.
42. Gianelli-Piperno A, Delgado E, Finkel V, Paxton W, Steinman RM. Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells. J Virol 1998; 72:2733-7.
43. Pope M, Betjes MG, Romani N, et al. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 1994; 78:389-98.
44. Pope M, Frankel S, Steinman R, Elmore D, Ho D, Marx P. Cutaneous dendritic cells promote replication of immunodeficiency viruses. Adv Exp Med Biol 1997; 417:395-9.
45. Pope M, Elmore D, Ho D, Marx P. Dendrite cell-T cell mixtures, isolated from the skin and mucosae of macaques, support the replication of SIV. AIDS Res Hum Retroviruses 1997; 13:819-27.
46. Granelli-Piperno A, Moser B, Pope M, et al. Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. J Exp Med 1996; 184:2433-8.
47. Spira AI, Marx PA, Patterson BK, et al. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J Exp Med 1996; 183:215-25.
48. Blauvelt A, Asada H, Saville MW, et al. Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways. J Clin Invest 1997; 100:2043-53.
49. Bakri Y, Schiffer C, Zennou V, et al. The maturation of dendritic cells results in postintegration inhibition of HIV-1 replication. J Immunol 2001; 166:3780-8.
50. Berger R, Gartner S, Rappersberger K, Foster C, Wolff K, Stingl G. Isolation of human immunodeficiency virus type 1 from human epidermis: virus replication and transmission studies. J Invest Dermatol 1992; 99:271-7.
51. Ramazzotti E, Marconi A, Re MC, et al. In vitro infection of human epidermal Langerhans' cells with HIV-1. Immunology 1995; 85:94-8.
52. Frankel SS, Wenig BM, Burke AP, et al. Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid. Science 1996; 272:115-7.
53. Frankel SS, Tenner-Racz K, Racz P, et al. Active replication of HIV-1 at the lymphoepithelial surface of the tonsil. Am J Pathol 1997; 151:89-96.
54. Moore JP. Coreceptors: implications for HIV pathogenesis and therapy. Science 1997; 276:51-2.
55. van't Wout AB, Kootstra NA, Mulder-Kampinga GA, et al. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J Clin Invest 1994; 94:2060-7.
56. Zhu T, Mo H, Wang N, et al. Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science 1993; 261:1179-81.
57. Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med 1997; 185:621-8.
58. Zoeteweij JP, Golding H, Mostowski H, Blauvelt A. Cytokines regulate expression and function of the HIV coreceptor CXCR4 on human mature dendritic cells. J Immunol 1998; 161:3219-23.
59. Agace WW, Amara A, Roberts AI, et al. Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation. Curr Biol 2000; 10:325-8.
60. Reece JC, Handley AJ, Anstee EJ, Morrison WA, Crowe SM, Cameron PU. HIV-1 selection by epidermal dendritic cells during transmission across human skin. J Exp Med 1998; 187:1623-31.