Dendritic cell-T cell mixtures, isolated from the skin and mucosae of macaques, support the replication of SIV

AIDS Research and Human Retroviruses

Volumn 13, Issue 10, 1997, Pages 819-827

  Pope, Melissa ^a   Elmore, David ^b   Ho, David ^a   Marx, Preston ^a,c  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Charles River Biomedical Resources Foundation Inc   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; MITOGENIC AGENT; RNA DIRECTED DNA POLYMERASE; VIRUS ANTIGEN; VIRUS PROTEIN;

ADENOID; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOPHENOTYPING; LEUKOCYTE; MACACA; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; SKIN; T LYMPHOCYTE; TONSIL; UTERINE CERVIX MUCOSA; VAGINA MUCOSA; VIRUS INFECTION; VIRUS ISOLATION; VIRUS REPLICATION; ANIMAL; CELL SEPARATION; CYTOLOGY; FEMALE GENITAL SYSTEM; HUMAN; MONKEY DISEASE; MUCOSA; NASOPHARYNX; PATHOGENICITY; PHYSIOLOGY; VIROLOGY;

ANIMALS; CELL SEPARATION; DENDRITIC CELLS; FEMALE; GENITALIA, FEMALE; HIV-1; HUMANS; MACACA FASCICULARIS; MACACA MULATTA; MUCOUS MEMBRANE; NASOPHARYNX; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SKIN; T-LYMPHOCYTES; VIRUS REPLICATION;

EID: 0030611117     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1997.13.819     Document Type: Article

References (53)

1. Steinman RM: The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991;9:271-296.
2. Steinman RM, Hoffman L, and Pope M: Maturation and migration of cutaneous dendritic cells. J Invest Dermatol 1995;105:2S-8S.
3. Inaba K, Metlay JP, Crowley MT, and Steinman RM: Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ. J Exp Med 1990;172:631-640.
4. Liu LM and MacPherson GG: Antigen acquisition by dendritic cells: Intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo. J Exp Med 1993;177:1299-1307.
5. Sornasse T, Flamand V, DeBecker G, Bazin H, Tielemans F, Thielemans K, Urbain J, Leo O, and Moser M: Antigen-pulsed dendritic cells can efficiently induce an antibody response in vivo. J Exp Med 1992;175:15-21.
6. Austyn JM, Kupiec-Weglinski JW, Hankins DF, and Morris PJ: Migration patterns of dendritic cells in the mouse. Homing to T cell-dependent areas of spleen, and binding within marginal zone. J Exp Med 1988;167:646-651.
7. Bujdoso R, Hopkins J, Dutia BM, Young P, and McConnell I: Characterization of sheep afferent lymph dendritic cells and their role in antigen carriage. J Exp Med 1989;170:1285-1302.
8. Daniels TE: Human mucosal Langerhans cells: Postmortem identification of regional variations in oral mucosa. J Invest Dermatol 1984;82:21-24.
9. Miller CJ, McChesney M, and Moore PF: Langerhans cells, macrophages and lymphocyte subsets in the cervix and vagina of rhesus macaques. Lab Invest 1992;67:628-634.
10. Miller CJ, McGhee JR, and Gardner MB: Biology of disease. Mucosal immunity, HIV transmission, and AIDS. Lab Invest 1993;68:129-145.
11. Fawcett DW: A Textbook of Histology, 11th Ed. W.B. Saunders, Philadelphia, 1986.
12. Pavli P, Woodhams CE, Doe WF, and Hume DA: Isolation and characterization of antigen-presenting dendritic cells from the mouse intestinal lamina propria. Immunology 1990;70:40-47.
13. Pavli P, Hume DA, Van de Pol E, and Doe WF: Dendritic cells, the main antigen-presenting cells of the human colonic lamina propria. Immunology 1993;78:132-141.
14. Pavli P, Mawell L, Van de Pol E, and Doe WF: Distribution of human colonic dendritic cells and macrophages. Clin Exp Immunol 1996;104:124-132.
15. Pope M, Betjes MGH, Romani N, Hirmand H, Cameron PU, Hoffman L, Gezelter S, Schuler G, and Steinman RM: Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 1994;78:389-398.
16. Pope M, Gezelter S, Gallo N, Hoffman L, and Steinman RM: Low levels of HIV-1 in cutaneous dendritic cells initiate a productive infection upon binding to memory CD4+ T cells. J Exp Med 1995;182:2045-2056.
17. Cameron PU, Freudenthal PS, Barker JM, Gezelter S, Inaba K, and Steinman RM: Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells. Science 1992;257:383-387.
18. Weissman D, Li Y, Ananworanich J, Zhou L-J, Adelsberger J, Tedder TF, Baseler M, and Fauci AS: Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1995;92:826-830.
19. Pinchuk LM, Polacino PS, Agy MB, Klaus SJ, and Clark EA: The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection. Immunity 1994;1:317-325.
20. Cameron P, Pope M, Granelli-Piperno A, and Steinman RM: Dendritic cells and the replication of HIV-1. J Leuk Biol 1996;59: 158-171.
21. Frankel SS, Wenig BM, Burke AP, Mannan P, Thompson LDR, Abbondanzo SL, Nelson AM, Pope M, and Steinman RM: Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid. Science 1996;272:115-117.
22. Pope M, Betjes MGH, Hirmand H, Hoffman L, and Steinman RM: Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T cell conjugates. J Invest Dermatol 1995;104:11-18.
23. Spira AI, Marx PA, Patterson BK, Mahoney J, Koup RA, Wolinsky SM, and Ho DD: Cellular targets of infection and route of viral dissemination following an intravaginal inoculation of SIV into rhesus macaques. J Exp Med 1996;183:215-225.
24. Miller CJ, Alexander NJ, Sutjipto S, Lackner AA, Gettie A, Hendrickx AG, Lowenstein LJ, Jennings M, and Marx PA: Genital mucosal transmission of simian immunodeficiency virus: Animal model for heterosexual transmission of human immunodeficiency virus. J Virol 1989;63:4277-4284.
25. Miller CJ, Alexander NJ, Sutjipto S, Hendrickx AG, Jennings M, and Marx PA: Effect of virus dose and nonoxynol-9 on the genital tract transmission of SIV in rhesus macaques. J Med Primatol 1990;19:401-409.
26. Shukla RC: Demonstration of the intermediate cells of Billingham and Medawar in the epidermis of Macaca mulatta and rhesus monkey. Acta Anatomica 1979;103:119-124.
27. Ringler DJ, Hancock WW, King NW, and Murphy GF: Characterization of nonhuman primate epidermal and dermal dendritic cells with monoclonal antibodies. A study of Langerhans and intermediate cells in the rhesus monkey. Lab Invest 1987;56:313-320.
28. Mosialos G, Yamashiro S, Baughman RW, Matusdaira P, Vara L, Matsumura F, Kieff E, and Birkenbach M: Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein. J Virol 1993;68:7320-7328.
29. Mosialos G, Birkenbach M, Ayehunie S, Matsumura F, Pinkus GS, Kieff E, and Langhoff E: Circulating human dendritic cells differentially express high levels of a 55-kd actin-bundling protein. Am J Pathol 1996;148:593-600.
30. Kashihara M, Ueda M, Horiguchi Y, Furukawa F, Hanaoka M, and Imamura S: A monoclonal antibody specifically reactive to human Langerhans cells. J Invest Dermatol 1986;87:602-607.
31. Letvin NL, Daniel MD, Sehgal PK, Desrosiers RC, Hunt RD, Waldron LM, MacKoy DK, Schmidt DK, Chalifoux LV, and King NW: Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science 1985;230:71-73.
32. Lewis M, Bellah S, McKinnon K, Yalley-Ogunro J, Zack PM, Elkins WR, Desrosiers RC, and Eddy GA: Titration and characterization of two rhesus-derived SIVmac challenge stocks. AIDS Res Hum Retroviruses 1994;10:213-220.
33. Naidu YM, Kestler HW, Li Y, Butler CV, Silva DP, Schmidt DK, Troup CD, Sehgal PK, Sonigo P, Daniel MD, et al.: Characterizetion of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 1: Persistent infection of rhesus monkeys with molecularly cloned SIV-mac. J Virol 1988;62:4691-4696.
34. Luciw PA, Shaw KE, Unger RE, Planelles V, Stout MW, Lackner JE, Pratt-Lowe E, Leung NJ, Banapour B, and Marthas ML: Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses 1992;8:395-402.
35. Kestler H, Kodama T, Ringler D, Marthas M, Pedersen N, Lackner A, Regier D, Sehgal P, Daniel M, King N, et al.: Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus. Science 1990;248:1109-1112.
36. Dulbecco R: End-point method measurement of the infectious titer of a viral sample. In: Virology (Dulbecco R and Ginsberg H, eds.), 2nd Ed. Lippincott, Philadelphia, 1988, pp. 22-25.
37. Sutjipto S, Kodama T, Yee J, Gettie A, Jennings M, Desrosiers RC, and Marx PA: Characterization of monoclonal antibodies that distinguish simian immunodeficiency virus isolates from each other and from human immunodeficiency virus types 1 and 2. J Gen Virol 1990;71:247-249.
38. Miller CJ, Alexander NJ, Vogel P, Anderson J, and Marx PA: Mechanism of genital transmission of SIV: A hypothesis based on transmission studies and the location of SIV in the genital tract of chronically infected female rhesus macaques. J Med Primatol 1992;21:64-68.
39. Fithian E, Kung P, Goldstein G, Rubenfeld M, Fenoglio C, and Edelson R: Reactivity of Langerhans cells with hybridoma antibody. Proc Natl Acad Sci USA 1988;78:2541-2544.
40. Inaba K, Witmer-Pack M, Inaba M, Hathcock KS, Sakuta H, Azuma M, Yagita H, Okumura K, Linsley PS, Ikehara S, et al.: The tissue distribution of the B7-2 costimulator in mice: Abundant expression on dendritic cells in situ and during maturation in vitro. J Exp Med 1994;180:1849-1860.
41. Caux C, Vanbervliet B, Massacrier C, Azuma M, Okumura K, Lanier LL, and Banchereau J: B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J Exp Med 1994;180:1841-1847.
42. Caux C, Massacrier C, Vanbervliet B, Dubois B, Van Kooten C, Durand I, and Banchereau J: Activation of human dendritic cells through CD40 cross-linking. J Exp Med 1994;180:1263-1272.
43. Peguet-Navarro J, Dalbiez-Gauthier C, Rattis F-M, Van Kooten C, Banchereau J, and Schmitt D: Functional expression of CD40 antigen on human epidermal Langerhans cells. J Immunol 1995;155: 4241-4247.
44. Flores-Romo L, Bjorck P, Duvert V, Van Kooten C, Saeland S, and Banchereau J: CD40 ligation on human CD34+ hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J Exp Med 1997;185:341-349.
45. Zhou L-J and Tedder TF: Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J Immunol 1995;154:3821-3835.
46. Takahashi K, Yamaguchi H, Ishizeki J, Nakajima T, and Nakazata Y: Immunohistochemical and immunoelectron microscopic localization of S-100 protein in the interdigitating reticulum cells of the human lymph node. Virchows Arch Cell Pathol 1981;37:125-135.
47. Shiro BC and Siegal GP: The use of monoclonal antibodies to S100 protein in diagnostic immunochemistry. In: Monoclonal Antibodies in Diagnostic Immunohistochemistry (Wick MR and Siegal GP, eds.). Marcel Dekker, New York, 1990, pp. 455-503.
48. Gerdes J, Lemke H, Baisch H, Wacker HH, Schwabb U, and Stein H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984;133:1710-1715.
49. Schluter C, Duchrow M, Wohlenberg C, Becker MG, Key G, Flad H-D, and Gerdes J: The cell proliferation-associated antigen of antibody Ki-67: A very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J Cell Biol 1993;123:513-522.
50. Granelli-Piperno A, Pope M, Inaba K, and Steinman RM: Coexpression of REL and SP1 transcription factors in HIV-1 induced, dendritic cell-T cell syncytia. Proc Natl Acad Sci USA 1995;92: 10944-10948.
51. Phillips DM and Bourinbaiar AS: Mechanism of HIV spread from lymphocytes to epithelia. Virology 1992;186:261-273.
52. Tan X and Phillips DM: Cell-mediated infection of cervix derived epithelial cells with primary isolates of human immunodeficiency virus. Arch Virol 1996;141:1177-1189.
53. Frankel SS, Tenner-Racz K, Racz P, Wenia BM, Hansen CH, Listinsky C, Heffner D, Nelson AM, Pope M, and Steinman RM: Active replication of HIV-1 in the lymphoepithelial regions of the nasopharyngeal and palatine tonsils. Am J Pathol 1997; in press.