Cyclic AMP Inhibits Extracellular Signal-regulated Kinase and Phosphatidylinositol 3-Kinase/Akt Pathways by Inhibiting Rap1

Journal of Biological Chemistry

Volumn 276, Issue 40, 2001, Pages 37242-37249

  Wang, Lai ^a   Liu, Feng ^a,b   Adamo, Martin L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES;

PHOSPHORYLATION;

BIOCHEMISTRY;

CARRIER PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN D2; EPAC PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN; PROTEIN KINASE B; PROTEIN P27; RAP 1 GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAP PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; UNCLASSIFIED DRUG; AKT1 PROTEIN, RAT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; RAP1 PROTEIN; RAPGEF3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GLIOMA CELL; GLIOMA CELL C6; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; RAT;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIVISION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RAP1 GTP-BINDING PROTEINS; RATS; TUMOR CELLS, CULTURED;

EID: 0035813228     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105089200     Document Type: Article

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