Enhanced cystatin C and lysosomal protease expression following 6-hydroxydopamine exposure

NeuroToxicology

Volumn 27, Issue 2, 2006, Pages 260-276

  Lee, Daniel C ^a   Close, Fran T ^a   Goodman, Carl B ^a   Jackson, Inneke M ^a   Wight Mason, Ceceile ^a   Wells, Lateesha M ^a   Womble, Tracy A ^a   Palm, Donald E ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

6 Hydroxydopamine (6 OHDA); Apoptosis; Cystatin C; Lysosomal proteases; Parkinson's; Pheochromocytoma cells (PC12)

Indexed keywords

ACETYLASPARTYLGLUTAMINYLVALYLASPARTYL ETHYLMETHYL KETONE; ASPARTIC PROTEINASE; CA 074ME; CASPASE 3; CASPASE 3 LIKE INHIBITOR; CATHEPSIN B; CATHEPSIN B INHIBITOR; CATHEPSIN D; CYSTATIN C; CYSTEINE; ENZYME INHIBITOR; LYSOSOMAL PROTEASE; LYSOSOME ENZYME; NEUROTOXIN; OXIDOPAMINE; PEPSTATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; EXPOSURE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CATHEPSIN B; CATHEPSIN D; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CYSTATINS; CYTOCHROMES C; DNA; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; LYSOSOMES; OXIDATIVE STRESS; OXIDOPAMINE; PC12 CELLS; PEPTIDE HYDROLASES; POLY(ADP-RIBOSE) POLYMERASES; RATS; STIMULATION, CHEMICAL; SYMPATHOLYTICS;

ANIMALIA;

EID: 32244445947     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2005.11.011     Document Type: Article

References (68)

1. E. Adamec, P.S. Mohan, A.M. Cataldo, J.P. Vonsattel, and R.A. Nixon Up-regulation of the lysosomal system in experimental models of neuronal injury: implication for Alzhiemer's disease Neuroscience 100 3 2000 663 675
2. T. Akopyan Protein inhibitors of proteinases from brain Neurochem Res 16 5 1991 513 517
3. R. Andrew, D.G. Watson, S.A. Best, J.M. Midgley, H. Wenlong, and R.K.H. Petty The determination of hydroxydopamine and other trace amines in urine of parkinsonian patients and normal controls Neurochem Res 18 11 1993 1175 1177
4. E. Aronica, E. van Viliet, E. Hendriksen, D. Troost, F. Lopes da Silva, and J. Gorter Cystatin C, a cysteine protease inhibitor, is persistently up-regulated in neurons and glia in a rat model for mesial temporal lobe epilepsy Eur J Neurosci 14 2001 1485 1495
5. A. Barrett Cystatin, the egg white inhibitor of cysteine proteinases Methods Enzymol 80 1981 771 818
6. E. Bednarski, and G. Lynch Cytosolic proteolysis of tau by cathepsin D in the hippocampus following suppression of cathepsin B and L J Neurochem 67 1996 1846 1855
7. L. Benuusi, R. Ghidoni, T. Steinhoff, A. Alberci, A. Villa, and F. Mazzoli Alzheimer diseased-associated cystatin C variant undergoes impaired secretion Neurobiol Dis 13 2003 15 21
8. H.G. Bernstein, M. Jarvinen, R. Pollanen, H. Schirpe, B. Knofel, and R. Rinne Cystatin C containing neurons in human postmortem hypothalamus Neurosci Lett 88 1988 131 134
9. L. Bjorck, P. Akesson, M. Bohus, J. Trojinar, M. Abrahamson, and I. Olafsson Bacterial growth blocked by a synthetic peptide based on the structure of a human proteinase inhibitor Nature 337 1989 385 386
10. L. Bjorck, A. Grubb, and L. Kjellen Cystatin C, a human proteinase inhibitor, blocks replication of herpes simplex virus J Virol 64 1990 941 943
11. D. Blum, S. Torch, N. Lambeng, M.F. Nissou, A.L. Benabid, and R. Sadoul Exracellular toxicity of 6-hydroxydopamine on PC 12 cells Neurosci Lett 283 2000 193 196
12. D. Blum, S. Torch, N. Lambeng, M.F. Nissou, A.L. Benabid, and R. Sadoul Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease Prog Neurobiol 65 2001 135 172
13. D. Blum, Y. Wu, M.F. Nissou, S. Arnaud, A.L. Benabid, and J.M. Verna p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells Brain Res 751 1997 139 142
14. B. Boland, and V. Campbell A B-mediated activation the apoptotic cascade in cultured cortical neurons: a role for cathepsin L Neurobiol Aging 25 2004 83 91
15. C. Calkins, M. Sameni, J. Koblinski, B. Sloane, and K. Moin Differential localization of cysteine protease inhibitors and a target cysteine protease, cathepsin B, by immuno-confocal microscopy J Histochem Cytochem 46 1998 745 751
16. A.M. Cataldo, D.J. Hamilton, and R.A. Nixon Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer's disease Brain Res 640 1994 68 80
17. M.J. Del Rio, and C. Velez-Pardo Monoamine neurotoxins-induced apoptosis in lymphocytes by a common oxidative stress mechanism: involvement of hydrogen peroxide, caspase-3, and nuclear factor kappa-β, p53, c-Jun transcription factors Biochem Pharm 63 2002 677 688
18. R.C. Dodel, Y. Du, K.R. Bales, Z. Ling, P.M. Carvey, and S.M. Paul Caspase-3-like protease and 6-hydroxydopamine induced neuronal cell death Mol Brain Res 64 1999 141 148
19. C.J. Duncan, and M.F. Rudge Are lysosomal enzymes involved in rapid damage in vertebrate muscle cells? Cell Tissue Res 253 1988 447 455
20. J. Emerit, M. Edeas, and F. Bricaire Neurodegenerative diseases and oxidative stress Biomed Pharmacother 58 2004 39 46
21. U. Felbor, B. Kessler, W. Mothes, H. Goebel, H.L. Ploegh, and R.T. Bronson Neuronal loss and brain atrophy in mice lacking cathepsin B and L Proc Natl Acad Sci USA 99 12 2002 7883 7888
22. L. Foghsgaard, D. Wissing, D. Mauch, U. Lademann, L. Bastholm, and M. Boes Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor J Cell Biol 5 2001 999 1009
23. M.F. Galindo, J. Jordan, G.C. Garcia, and V. Cena Chromaffin cell death induced by 6-hydroxydopamine is independent of mitochondrial swelling and caspase activation J Neurochem 84 2003 1066 1073
24. R. Graumann, I. Paris, P. Alvarado, P. Rumanque, C. Pastene, and S. Cardenas Oxidation of dopamine to aminochrome as a mechanism for neurodegeneration of dopaminergic systems in Parkinson's disease. Possible neuroprotective role of DT-diaphorase Pol J Pharmacol 54 2002 573 579
25. A. Grubb, and H. Lofberg Human g-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis Proc Natl Acad Sci USA 79 1982 3024 3027
26. B. Han, H.S. Hong, W.S. Choi, G. Markelonis, T.H. Oh, and Y.J. Oh Caspase-dependent and independent cell death pathways in primary cultures of mesencephalic dopaminergic neurons after neurotoxin treatment J Neurosci 23 12 2003 5069 5078
27. H.K. Hawkins, J.L.E. Ericsson, P. Biberfeld, and B.F. Trump Lysosomes and phagosome stability in lethal cell injury Am J Pathol 68 1977 255 288
28. K. Isahara, Y. Ohsawa, S. Kanamori, M. Shibata, S. Waguri, and N. Sato Regulation of a novel pathway for cell death by lysosomal aspartic and cysteine proteinases Neuroscience 91 1 1999 233 249
29. H. Jung, E. Lee, and S. Lee Age-related changes in ultrastructural features cathepsin B- and D-containing neurons in rat cerebral cortex Brain Res 1-2 1999 43 54
30. H. Kikuchi, T. Yamada, H. Furuya, K. Doh-ura, Y. Ohyagi, and T. Iwaki Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis Acta Neuropathol 105 2003 462 468
31. P.J. Kingham, and J.M. Pocock Microglial secreted cathepsin B induces neuronal apoptosis J Neurochem 76 2001 1475 1484
32. J. Leung-Tack, C. Tavara, M.C. Gensac, J. Martinez, and A. Colle Modulation of phagocytosis-associated respiratory burst by human cystatin C: role of the N-terminal tetrapeptide Lys-Pro-Pro-Arg Exp Cell Res 188 1990 16 22
33. J. Leung-Tack, C. Tavara, J. Martinez, and A. Colle Neutrophil chemotactic activity is modulated by human cystatin C, an inhibitor of cysteine proteases Inflammation 14 3 1990 247 258
34. N. Lev, E. Melamed, and D. Offen Apoptosis and Parkinson's disease Prog Neuro-Psychopharmacol Biol Psychiatry 27 2003 245 250
35. E. Levy, M. Sastre, A. Kumar, G. Gallo, P. Piccardo, and B. Ghetti Co-deposition of cystatin C with amyloid-beta protein in the brain of Alzheimer disease patients J Neuropathol Exp Neurol 60 2001 94 104
36. H. Lofberg, and A.O. Grubb Quantitation of gamma-trace in human biological fluids: indication for production in the central nervous system Scand J Clin Lab Invest 39 1979 619 626
37. K.M.C.N. Luhr, K. Elin, P. Low, and K. Kristensson Cathepsin B and L are involved in degradation of Prions in GT1-1 neuronal cells Neuroreport 15 10 2004 1663 1667
38. K. Lukasiuk, T. Pirttila, and A. Pitkanen Up-regulation of cystatin C expression in the rat hippocampus during epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy Epilepsia 43 2002 137 145
39. A. Mannes, B. Martin, H. Yang, J. Keller, S. Lewin, and R. Gaiser Cystatin C as a cerebrospinal fluid biomarker for pain in humans Pain 102 2003 251 256
40. N. Marks, M.J. Berg, R.C. Makofske, and W. Danho Synthetic domains of cystatin linked to enkephalins are novel inhibitors of brain cathepsins L/B Peptides 11 1990 679 682
41. G.B. McHolm Lipofuscin in amyotrophic lateral sclerosis Arch Neurol 41 1984 1187 1188
42. T. Miyake, Y. Gahata, M. Nakayama, H. Yamada, K. Uwabe, and T. Kitamura Up-regulation of cystatin C by microglia in the rat facial nucleus following axotomy Mol Brain Res 37 1996 273 282
43. A. Nagai, J. Ryu, S. Kobayashi, and S. Kim Cystatin C induces neuronal cell death in vivo Ann NY Acad Sci 977 2002 315 321
44. H. Nakanishi, K. Tominaga, T. Amano, I. Hirotsu, T. Inoue, and K. Yamamoto Age related changes in activities and localizations of cathepsins D, E, B and L in rat brain tissues Exp Neurol 126 1994 119 128
45. C. Nishio, K. Yoshida, K. Nishiyama, H. Hatanaka, and M. Yamada Involvement of cystatin C in oxidative stress-induced apoptosis of cultured rat CNS neurons Brain Res 873 2000 252 262
46. T. Nitatori, S. Noboru, S. Waguri, Y. Karasawa, H. Araki, and K. Shibanai Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis J Neurosci 15 2 1995 1001 1011
47. R.A. Nixon, A.M. Cataldo, P.A. Paskevich, D.J. Hamilton, T.R. Wheelock, and L. Kanaley-Andrews The lysosomal system in neurons; involvement at multiple stages of Alzheimer's disease pathogenesis Ann NY Acad Sci 674 1992 65 88
48. K.H.S. Okamoto, M. Amari, M. Watanabe, and A. Sakurai Bunina bodies in amyotrophic lateral sclerosis immunostained with rabbit anti-cystatin C serum Neurosci Lett 162 1993 125 128
49. K. Ollinger Inhibition of cathepsin D prevents free radical induced apoptosis in rat myocardiocytes Arch Biochem Biophys 373 2 2000 346 351
50. D.E. Palm, N.W. Knuckey, M.J. Primiano, A.G. Spangenberger, and C.E. Johanson Cystatin C, a protease inhibitor, in degenerating rat hippocampal neurons following transient forebrain ischemia Brain Res 691 1995 1 8
51. R.J. Riese, and H.A. Chapman Cathepsin and compartmentalization in antigen presentation Curr Opin Immunol 12 2000 107 113
52. K. Roberg, U. Johansson, and K. Ollinger Lysosomal release of cathepsin D precedes relocation of cytochrome C and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress Free Radic Biol Med 27 11/12 1999 1228 1237
53. M. Rodriguez, P. Barroso-Chinea, P. Abdala, J. Obese, and T. Gonzalez-Hernandez Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: similarities with cell loss in Parkinson's disease Exp Neurol 169 2001 163 181
54. D. Seyfried, Y. Han, Z. Zheng, N. Day, K. Moin, and S. Rempel Cathepsin B and middle cerebral artery occlusion in the rat J Neurosurg 87 1997 716 723
55. M. Shibata, S. Kanamori, K. Isahara, Y. Ohsawa, A. Konishi, and S. Kametaka Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation Biochem Biophys Res Commun 251 1998 199 203
56. N. Takai, H. Nakanishi, K. Tanabe, T. Nishioku, T. Sugiyama, and M. Fujiwara Involvement of caspase-like proteinases in apoptosis of neuronal PC 12 cells and primary cultured microglial induced by 6-hydroxydopamine J Neurosci Res 54 1998 214 222
57. K. Takuma, M. Kiriu, K. Mori, E. Lee, R. Enomoto, and A. Baba Roles of cathepsins in reperfusion-induced apoptosis in cultured astrocytes Neurochem Int 1246 2002 1 7
58. C. Tavera, D. Prevot, J.P. Girolami, J. Leung-Tack, and A. Colle Tissue and biological fluid distribution of cysteine proteinases inhibitor: rat cystatin C Biol Chem Hoppe-Seyler 371 1990 187 192
59. M.S. Thibodeau, C. Giardina, D.A. Knecht, J. Helble, and A.K. Hubbard Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity Toxicol Sci 80 2004 34 48
60. K. Tieu, P.C. Ash, D.M. Zuo, and P.H. Yu Inhibition of 6-hydroxydopamine-induced p53 expression and survival of neuroblastoma cells following interaction with astrocytes Neuroscience 103 1 2001 125 132
61. A.H. Warfel, D. Sucker-Franklin, B. Frangione, and J. Ghiso Constitutive secretion of cystatin C (gamma-trace) by monocytes and macrophages and its downregulation after stimulation J Exp Med 166 1987 1912 1917
62. L. Wei, Y. Berman, E. Castano, M. Cadena, R. Beavis, and L. Devi Instability of amyloidogenic cystatin C variant of hereditary cerebral hemorrhage with amyloidosis J Biol Chem 273 1998 11806 11814
63. C. Winkler, D. Kirik, A. Bjorklund, and M.A. Cenci l-Dopa-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of Parkinson's disease: relation to motor and cellular parameter of nigrostriatal function Neurobiol Dis 10 2002 165 186
64. Y. Wu, D. Blum, M.F. Nissou, A.L. Benabid, and J.M. Verna Unlike MPP, apoptosis induced by 6-OHDA in PC12 cells is independent of mitochondrial inhibition Neurosci Lett 221 1996 69 71
65. L. Xu, J. Sheng, T. Zhongshu, X. Wu, Y. Yu, and H. Guo Cystatin C prevents degeneration of rat nigral dopaminergic neurons: in vitro and in vivo studies Neurobiol Dis 18 2005 152 165
66. R.H. Xu, J. Liu, X.W. Chen, F. Xu, Q. Xie, and H. Yu Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells Brain Res 899 2001 10 19
67. T. Yamashima Implication of cysteine protease calpain, cathepsin and caspase in ischemic neuronal death of primates Prog Neurobiol 62 2000 273 295
68. O. Yasuhara, K. Hanai, I. Ohkubo, M. Sasaki, P.L. McGreer, and H. Kimura Expression of cystatin C in rat, monkey and human brains Brain Res 628 1993 85 92