Oxidation of dopamine to aminochrome as a mechanism for neurodegeneration of dopaminergic systems in Parkinson's disease. Possible neuroprotective role of DT-diaphorase

Polish Journal of Pharmacology

Volumn 54, Issue 6, 2002, Pages 573-579

  Graumann, Rebecca ^a   Paris, Irmgard ^a   Martinez Alvarado, Pedro ^a   Rumanque, Pamela ^a   Perez Pastene, Carolina ^a   Cardenas, Sergio P ^a   Marin, Pablo ^a   Diaz Grez, Fernando ^a   Caviedes, Raul ^a   Caviedes, Pablo ^a   Segura Aguilar, Juan ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

Dopamine; DT diaphorase; Neurotoxicity; Pakinson's disease

Indexed keywords

AMIFLAMINE; AMINE OXIDASE (FLAVIN CONTAINING); APOMORPHINE; CATECHOLAMINE; COMPLEMENTARY DNA; COPPER; CYTOSINE; DICOUMAROL; DIHYDROLIPOAMIDE DEHYDROGENASE; DOPAMINE; FREE RADICAL; MANGANESE; MONOAMINE OXIDASE INHIBITOR; SEMIQUINONE; THIAMINE;

ANTIOXIDANT ACTIVITY; DOPAMINE METABOLISM; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; DRUG EFFECT; ENZYME INHIBITION; GENE EXPRESSION; GENETIC POLYMORPHISM; GLUTATHIONE METABOLISM; HUMAN; IN VIVO STUDY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION; PARKINSON DISEASE; POINT MUTATION; REGULATORY MECHANISM; REVIEW; STRIATONIGRAL DEGENERATION; SUBSTANTIA NIGRA; SYNAPSE VESICLE;

ANIMALS; DOPAMINE; HUMANS; INDOLEQUINONES; INDOLES; NAD(P)H DEHYDROGENASE (QUINONE); NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; OXIDATION-REDUCTION; PARKINSON DISEASE;

EID: 0036968124     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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