Correction: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5 (Journal of Cell Science (2006) 119 (47-55) DOI: 10.1242/jcs.02697);FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5

Journal of Cell Science

Volumn 119, Issue 1, 2006, Pages 47-55

  Li, Weiquan ^a   Aurandt, Jennifer ^a,b   Jürgense, Claudia ^c   Rao, Yi ^c   Guan, Kun Liang ^a,b,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

DCC; Deleted in colorectal cancer; FAK; Focal adhesion kinase; Netrin signaling; Src family tyrosine kinases; Tyrosine phosphorylation; UNC5 receptor

Indexed keywords

FOCAL ADHESION KINASE; NETRIN; PROTEIN SH2; PROTEIN TYROSINE KINASE; PROTEIN UNC5; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL MIGRATION; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPINAL CORD;

ANIMALIA;

EID: 31644442908     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.230342     Document Type: Erratum

References (63)

1. Arakawa, H. (2004). Netrin-1 and its receptors in tumorigenesis. Nat. Rev. Cancer 4, 978-987.
2. Bashaw, G. J. and Goodman, C. S. (1999). Chimeric axon guidance receptors: the cytoplasmic domains of slit and nettin receptors specify attraction versus repulsion. Cell 97, 917-926.
3. Brouns, M. R., Matheson, S. F. and Settleman, J. (2001). p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat. Cell Biol. 3, 361-367.
4. Calalb, M. B., Polte, T. R. and Hanks, S. K. (1995). Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol. Cell. Biol. 15, 954-963.
5. Carter, N., Nakamoto, T., Hirai, H. and Hunter, T. (2002). EphrinA1-induced cytoskeletal re-organization requires FAK and p130 (cas). Nat. Cell Biol. 4, 565-573.
6. Cary, L. A. and Guan, J. L. (1999). Focal adhesion kinase in integrin-mediated signaling. Front Biosci. 4, D102-D113.
7. Chan, S. S., Zheng, H., Su, M. W., Wilk, R., Killeen, M. T., Hedgecock, E. M. and Culotti, J. G. (1996). UNC-40, a C. elegans homolog of DCC (deleted in colorectal cancer), is required in motile cells responding to UNC-6 netrin cues. Cell 87, 187-195.
8. Chang, C., Yu, T. W., Bargmann, C. I. and Tessier-Lavigne, M. (2004). Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase. Science 305, 103-106.
9. Cobb, B. S., Schaller, M. D., Leu, T. H. and Parsons, J. T. (1994). Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK. Mol. Cell. Biol. 14, 147-155.
10. Cooper, L. A., Shen, T. L. and Guan, J. L. (2003). Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction. Mol. Cell. Biol. 23, 8030-8041.
11. Fearon, E. R., Cho, K. R., Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A. C., Thomas, G., Kinzler, K. W. et al. (1990). Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247, 49-56.
12. Forcet, C., Ye, X., Granger, L., Corset, V., Shin, H., Bredesen, D. E. and Mehlen, P. (2001). The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation. Proc. Natl. Acad. Sci. USA 98, 3416-3421.
13. Gao, X., Honn, K. V., Grignon, D., Sakr, W. and Chen, Y. Q. (1993). Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas. Cancer Res. 53, 2723-2727.
14. Guan, J. L. (1997). Role of focal adhesion kinase in integrin signaling. Int. J. Biochem. Cell Biol. 29, 1085-1096.
15. Hamelin, M., Zhou, Y., So, M. W., Scott, I. M. and Culotti, J. G. (1993). Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally. Nature 364, 327-330.
16. Hebrok, M. and Reichardt, L. F. (2004). Brain meets pancreas: netrin, an axon guidance molecule, controls epithelial cell migration. Trends Cell. Biol. 14, 153-155.
17. Hedgecock, E. M., Culotti, J. G. and Hall, D. H. (1990). The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron 4, 61-85.
18. Hinck, L. (2004). The versatile roles of "axon guidance" cues in tissue morphogenesis. Dev. Cell 7, 783-793.
19. Hong, K., Hinck, L., Nishiyama, M., Poo, M. M., Tessier-Lavigne, M. and Stein, E. (1999). A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell 97, 927-941.
20. Ishii, N., Wadsworth, W. G., Stern, B. D., Culotti, J. G. and Hedgecock, E. M. (1992). UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans. Neuron 9, 873-881.
21. Itoh, F., Hinoda, Y., Ohe, M., Ohe, Y., Ban, T., Endo, T., Imai, K. and Yachi, A. (1993). Decreased expression of DCC mRNA in human colorectal cancers. Int. J. Cancer 53, 260-263.
22. Jarjour, A. A., Manitt, C., Moore, S. W., Thompson, K. M., Yuh, S. J. and Kennedy, T. E. (2003). Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord. J. Neurosci. 23, 3735-3744.
23. Kalia, L. V., Gingrich, J. R. and Salter, M. W. (2004). Src in synaptic transmission and plasticity. Oncogene 23, 8007-8016.
24. Keino-Masu, K., Masu, M., Hinck, L., Leonardo, E. D., Chan, S. S., Culotti, J. G. and Tessier-Lavigne, M. (1996). Deleted in colorectal cancer (DCC) encodes a netrin receptor. Cell 87, 175-185.
25. Keleman, K. and Dickson, B. J. (2001). Short- and long-range repulsion by the Drosophila Unc5 netrin receptor. Neuron 32, 605-617.
26. Kennedy, T. E. (2000). Cellular mechanisms of netrin function: long-range and short-range actions. Biochem. Cell Biol. 78, 569-575.
27. Kennedy, T. E., Serafini, T., de la Torre, J. R. and Tessier-Lavigne, M. (1994). Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78, 425-435.
28. Kikuchi-Yanoshita, R., Konishi, M., Fukunari, H., Tanaka, K. and Miyaki, M. (1992). Loss of expression of the DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis and non-familial adenomatous polyposis patients. Cancer Res. 52, 3801-3803.
29. Killeen, M., Tong, J., Krizus, A., Steven, R., Scott, I., Pawson, T. and Culotti, J. (2002). UNC-5 function requires phosphorylation of cytoplasmic tyrosine 482, but its UNC-40-independent functions also require a region between the ZU-5 and death domains. Dev. Biol. 251, 348-366.
30. Knoll, B. and Drescher, U. (2004). Src family kinases are involved in EphA receptor-mediated retinal axon guidance. J. Neurosci. 24, 6248-6257.
31. Lee, J., Li, W. and Guan, K. L. (2005). SRC-1 mediates Unc-5 signaling in Caenorhabditis elegans. Mol. Cell. Biol. 25, 6485-6495.
32. Leonardo, E. D., Hinck, L., Masu, M., Keino-Masu, K., Ackerman, S. L. and Tessier-Lavigne, M. (1997). Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors. Nature 386, 833-838.
33. Leung-Hagesteijn, C., Spence, A. M., Stern, B. D., Zhou, Y., So, M. W., Hedgecock, E. M. and Culotti, J. G. (1992). UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Cell 71, 289-299.
34. Li, W., Lee, J., Vikis, H. G., Lee, S. H., Liu, G., Aurandt, J., Shen, T. L., Fearon, E. R., Guan, J. L., Han, M. et al. (2004). Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nat. Neurosci. 7, 1213-1221.
35. Liu, G., Beggs, H., Jurgensen, C., Park, H. T., Tang, H., Gorski, J., Jones, K. R., Reichardt, L. F., Wu, J. and Rao, Y. (2004a). Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction. Nat. Neurosci. 7, 1222-1232.
36. Liu, Y., Stein, E., Oliver, T., Li, Y., Brunken, W. J., Koch, M., Tessier-Lavigne, M. and Hogan, B. L. (2004b). Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis. Curr. Biol. 14, 897-905.
37. Livesey, F. J. and Hunt, S. F. (1997). Netrin and netrin receptor expression in the embryonic mammalian nervous system suggests roles in retinal, striatal, nigral, and cerebellar development. Mol. Cell Neurosci. 8, 417-429.
38. Llambi, F., Causeret, F., Bloch-Gallego, E. and Mehlen, P. (2001). Netrin-1 acts as a survival factor via its receptors UNC5H and DCC. EMBO J. 20, 2715-2722.
39. Lowell, C. A. and Soriano, P. (1996). Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories. Genes Dev. 10, 1845-1857.
40. Lu, X., Le Noble, F., Yuan, L., Jiang, Q., De Lafarge, B., Sugiyama, D., Breant, C., Claes, F., De Smet, F., Thomas, J. L. et al. (2004). The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 432, 179-186.
41. Mazelin, L., Bernet, A., Bonod-Bidaud, C., Pays, L., Arnaud, S., Gespach, C., Bredesen, D. E., Scoazec, J. Y. and Mehlen, P. (2004). Netrin-1 controls colorectal tumorigenesis by regulating apoptosis. Nature 431, 80-84.
42. Mehlen, P. and Fearon, E. R. (2004). Role of the dependence receptor DCC in colorectal cancer pathogenesis. J. Clin. Oncol. 22, 3420-3428.
43. Mehlen, P., Rabizadeh, S., Snipas, S. J., Assa-Munt, N., Salvesen, G. S. and Bredesen, D. E. (1998). The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis. Nature 395, 801-804.
44. Meriane, M., Tcherkezian, J., Webber, C. A., Danek, E. I., Triki, I., McFarlane, S., Bloch-Gallego, E. and Lamarche-Vane, N. (2004). Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance. J. Cell Biol. 167, 687-698.
45. Merz, D. C. and Culotti, J. G. (1999). Getting directions: axon guidance receptors find the way. Sci. STKE 1999, PE1.
46. Merz, D. C., Zheng, H., Killeen, M. T., Krizus, A. and Culotti, J. G. (2001). Multiple signaling mechanisms of the UNC-6/netrin receptors UNC-5 and UNC-40/DCC in vivo. Genetics 158, 1071-1080.
47. Nikolopoulos, S. and Giancotti, F. (2005). Netrin-integrin Signaling in Epithelial Morphogenesis, Axon Guidance and Vascular Patterning. Cell Cycle 4, 131-135.
48. Palmer, A., Zimmer, M., Erdmann, K. S., Eulenburg, V., Porthin, A., Heumann, R., Deutsch, U. and Klein, R. (2002). EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol. Cell 9, 725-737.
49. Park, K. W., Crouse, D., Lee, M., Karnik, S. K., Sorensen, L. K., Murphy, K. J., Kuo, C. J. and Li, D. Y. (2004). The axonal attractant Netrin-1 is an angiogenic factor. Proc. Natl. Acad. Sci. USA 101, 16210-16215.
50. Ren, X. R., Ming, G. L., Xie, Y., Hong, Y., Sun, D. M., Zhao, Z. Q., Feng, Z., Wang, Q., Shim, S., Chen, Z. F. et al. (2004). Focal adhesion kinase in netrin-1 signaling. Nat. Neurosci. 7, 1204-1212.
51. Salminen, M., Meyer, B. I., Bober, E. and Gruss, F. (2000). Netrin 1 is required for semicircular canal formation in the mouse inner ear. Development 127, 13-22.
52. Schlaepfer, D. D., Hauck, C. R. and Sieg, D. J. (t999). Signaling through focal adhesion kinase. Prog. Biophys. Mol. Biol. 71, 435-478.
53. Serafini, T., Kennedy, T. E., Galko, M. J., Mirzayan, C., Jessell, T. M. and Tessier-Lavigne, M. (1994). The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 78, 409-424.
54. Srinivasan, K., Strickland, P., Valdes, A., Shin, G. C. and Hinck, L. (2003). Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis. Dev. Cell 4, 371-382.
55. Stein, E. and Tessier-Lavigne, M. (2001). Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex. Science 291, 1928-1938.
56. Su, M., Merz, D. C., Killeen, M. T., Zhou, Y., Zheng, H., Kramer, J. M., Hedgecock, E. M. and Culotti, J. G. (2000). Regulation of the UNC-5 netrin receptor initiates the first reorientation of migrating distal tip cells in Caenorhabditis elegans. Development 127, 585-594.
57. Takahashi, T., Fournier, A., Nakamura, F., Wang, L. H., Murakami, Y., Kalb, R. G., Fujisawa, H. and Strittmatter, S. M. (1999). Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99, 59-69.
58. Tatosyan, A. G. and Mizenina, O. A. (2000). Kinases of the Src family: structure and functions. Biochemistry (Mosc.) 65, 49-58.
59. Tessier-Lavigne, M. and Goodman, C. S. (1996). The molecular biology of axon guidance. Science 274, 1123-1133.
60. Thomas, S. M. and Brugge, J. S. (1997). Cellular functions regulated by Src family kinases. Annu. Rev. Cell Dev. Biol. 13, 513-609.
61. Tong, J., Killeen, M., Steven, R., Binns, K. L., Culotti, J. and Pawson, T. (2001). Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain. J. Biol. Chem. 276, 40917-40925.
62. Uchino, S., Tsuda, H., Noguchi, M., Yokota, J., Terada, M., Saito, T., Kobayashi, M., Sugimura, T. and Hirohashi, S. (1992). Frequent loss of heterozygosity at the DCC locus in gastric cancer. Cancer Res. 52, 3099-3102.
63. Wadsworth, W. G., Bhatt, H. and Hedgecock, E. M. (1996). Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans. Neuron 16, 35-46.