Cellular mechanisms of netrin function: Long-range and short-range actions

Biochemistry and Cell Biology

Volumn 78, Issue 5, 2000, Pages 569-575

  Kennedy, T E ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NETRIN;

ANIMAL CELL; ASSOCIATION; CELL INTERACTION; CELL SURFACE; COLORECTAL CANCER; CONFERENCE PAPER; NERVE CELL DIFFERENTIATION; NERVE GROWTH; NONHUMAN; PROTEIN FAMILY; RECEPTOR BINDING;

ANIMALIA;

EID: 0033695762     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o00-079     Document Type: Conference Paper

References (60)

1. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein
2. The NTR module: Domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases
3. Multiple factors govern intraretinal axon guidance: A time lapse study
4. Unique changes of ganglion cell growth cone behavior following cell adhesion molecule perturbations: A time-lapse study of the living retina
5. UNC-40, a C. elegans homolog of DCC (Deleted in colorectal cancer), is required in motile cells responding to UNC-6 netrin cues
6. DCC: Linking tumor suppressor genes and altered cell surface interactions in cancer?
7. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons
8. Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans
9. Netrin-1 and DCC mediate axon guidance at the optic disc: Loss of function leads to optic nerve hypoplasia
10. Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC
11. DCC expression is altered by multiple mechanisms in brain tumors
12. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene
13. Identification of a chromosome 18q gene that is altered in colorectal cancers
14. The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina
15. Axon growth in embryonic chick and quail retinal whole mounts in vitro
16. Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally
17. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans
18. The DCC gene product in cellular differentiation and colorectal tumorigenesis
19. Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers
20. A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion
21. UNC-6, a laminin-related protein, guides cell and pioneer axons and mesodermal cells on the epidermis in C. elegans
22. Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1
23. Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis
24. Deleted in colorectal cancer (dcc) encodes a netrin receptor
25. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord
26. Semaphorin-mediated neuronal growth cone guidance
27. Frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance
28. Axon tracts correlate with netrin-1a expression in the zebrafish embryo
29. Vertebrate homologues of C. elgans unc-5 are candidate netrin receptors
30. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans
31. Netrin and netrin receptor expression in the embryonic mammalian nervous system suggests roles in retinal, striatal, nigral, and cerebellar development
32. Netrin-1 is expressed by neurons and oligodendrocytes in the post-natal and adult mammalian spinal cord
33. Identification and characterization of neogenin, a DCC-related gene
34. Netrin-1: Interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas
35. Genes necessary for directed axonal elongation or fasciculation in C. elegans
36. cAMP-dependent growth cone guidance by netrin-1
37. Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons
38. Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant
39. La retine des vertebres
40. Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues
41. Adhesive interactions that regulate development of the retina and primary visual projections
42. Loss of DCC expression and glioma progression
43. Distal recognition site for classical pathway convertase located in the C345C/Netrin module of complement component C5
44. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
45. Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system
46. Guidance of circumferentially growing axons by netrin-dependent and -independent floor plate chemotropism in the vertebrate brain
47. Capturing genes encoding membrane and secreted proteins important for mouse development
48. Expression and regulation of a netrin homologue in the zebrafish embryo
49. The molecular biology of axon guidance
50. Chemotropic guidance of developing axons in the mammalian central nervous system
51. The laminins
52. The NTN2L gene encoding a novel human netrin maps to the autosomal dominant polycyctic kidney disease region on chromosome 16p13.3
53. Motor axon subpopulations respond differentially to the chemorepellents netrin-1 and semaphorin D
54. Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer
55. Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans
56. Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching
57. Croissance des fibres nerveuses commissurales lors de lesions de la moelle epiniere chez de jeunes embryons de Poulet
58. Genetic analysis of the mechanisms controlling target selection: Complementary and combinatorial functions of netrins, semaphorins, and IgCMAs
59. Identification and expression of mouse netrin-4