Short- and long-range repulsion by the Drosophila Unc5 Netrin receptor

Neuron

Volumn 32, Issue 4, 2001, Pages 605-617

  Keleman, Krystyna ^a   Dickson, Barry J ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

M PROTEIN; NETRIN; PROTEIN UNC5; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DROSOPHILA; NERVE CELL GROWTH; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY;

EID: 0035923748     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00505-0     Document Type: Article

References (48)

1. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein
2. The genome sequence of Drosophila melanogaster
3. Chimeric axon guidance receptors: The cytoplasmic domains of Slit and Netrin receptors specify attraction versus repulsion
4. Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects
5. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
6. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
7. UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues
8. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons
9. Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans
10. Genetic analysis of the mechanisms controlling target selection: Target-derived Fasciclin II regulates the pattern of synapse formation
11. Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo
12. Phenotype of mice lacking functional Deleted in colorectal cancer (DCC) gene
13. The Netrin receptor Frazzled is required in the target for establishment of retinal projections in the Drosophila visual system
14. Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally
15. Guidance cues at the Drosophila CNS midline: Identification and characterization of two Drosophila Netrin/UNC-6 homologs
16. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans
17. The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution
18. The death domain motif found in Fas (Apo-1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance
19. A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion
20. UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans
21. Deleted in Colorectal Cancer (DCC) encodes a netrin receptor
22. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord
23. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
24. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
25. Slit is the midline repellent for the Robo receptor in Drosophila
26. Frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance
27. Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors
28. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans
29. cAMP-dependent growth cone guidance by netrin-1
30. Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons
31. Crossing the midline: Roles and regulation of Robo receptors
32. Selecting a longitudinal pathway: Robo receptors specify the lateral position of axons in the Drosophila CNS
33. A Drosophila complementary DNA resource
34. SMART, a simple modular architecture research tool: Identification of signaling domains
35. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
36. Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system
37. Guidance of circumferentially growing axons by netrin-dependent and -independent floor plate chemotropism in the vertebrate brain
38. Short-range and long-range guidance by Slit and its Robo receptors: A combinatorial code of Robo receptors controls lateral position
39. Short-range and long-range guidance by Slit and its Robo receptors. Robo and Robo 2 play distinct roles in midline guidance
40. Mesectodermal cell fate analysis in Drosophila midline mutants
41. Hierarchical organization of guidance receptors: Silencing of netrin attraction by slit through a Robo/DCC receptor complex
42. Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation
43. Two TNF receptors
44. Commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein
45. Genes that control neuromuscular specificity in Drosophila
46. Motor axon subpopulations respond differentially to the chemorepellents netrin-1 and semaphorin D
47. Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans
48. Genetic analysis of the mechanisms controlling target selection: Complementary and combinatorial functions of Netrins, Semaphorins, and IgCAMs