Influence of naturally occuring insertions in the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and mutation frequencies in vitro

Journal of General Virology

Volumn 87, Issue 2, 2006, Pages 419-428

  Curr, Kenneth ^a,b   Tripathi, Snehlata ^c   Lennerstrand, Johan ^d   Larder, Brendan A ^e   Prasad, Vinayaka R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HIV Resistance Response Database Initiative   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA GALACTOSIDASE; RNA DIRECTED DNA POLYMERASE; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; NUCLEOSIDE; PRIMER DNA;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA SYNTHESIS; DNA TEMPLATE; ENZYME STRUCTURE; GENE FREQUENCY; GENE INSERTION; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRUS MUTANT; VIRUS MUTATION; VIRUS RECOMBINANT; VIRUS RESISTANCE; WILD TYPE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; CHEMISTRY; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MUTATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SUBSTITUTION; ANTI-HIV AGENTS; CATALYTIC DOMAIN; DNA PRIMERS; DRUG RESISTANCE, VIRAL; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MUTATION; NUCLEOSIDES;

EID: 31644432212     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81458-0     Document Type: Article

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