SCOPUS 정보 검색 플랫폼

Volumn 277, Issue 25, 2002, Pages 22345-22352

Substitutions of Phe61 located in the vicinity of template 5′-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase

(2) Fisher, Timothy S a Prasad, Vinayaka R a

a ALBERT EINSTEIN COLLEGE OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; DNA; ENZYME INHIBITION; TERNARY SYSTEMS;

STRUCTURAL DETERMINANTS;

BIOCHEMISTRY;

2',3' DIDEOXYTHYMIDINE TRIPHOSPHATE; DNA POLYMERASE; NUCLEOSIDE ANALOG; PHENYLALANINE; RNA DIRECTED DNA POLYMERASE; STAVUDINE; ADENOSINE TRIPHOSPHATE; ALANINE; DNA; LEUCINE; PYRIMIDINE NUCLEOTIDE; RECOMBINANT PROTEIN; THYMIDINE 5'-TRIPHOSPHATE; THYMIDINE TRIPHOSPHATE; TRYPTOPHAN; TYROSINE;

5' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; BINDING SITE; CRYSTAL STRUCTURE; DNA TEMPLATE; ENZYME STRUCTURE; GENE MUTATION; GENETIC CONSERVATION; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTAGENESIS; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; BASE MISPAIRING; CHEMISTRY; DIMERIZATION; IC 50; KINETICS; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

ADENOSINE TRIPHOSPHATE; ALANINE; BASE PAIR MISMATCH; DIMERIZATION; DNA; HIV-1 REVERSE TRANSCRIPTASE; INHIBITORY CONCENTRATION 50; KINETICS; LEUCINE; MUTAGENESIS; MUTATION; PHENOTYPE; PHENYLALANINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; THYMINE NUCLEOTIDES; TRYPTOPHAN; TYROSINE;

EID: 0037150445 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M200282200 Document Type: Article

Times cited : (36)

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