RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase

Oncogene

Volumn 22, Issue 28, 2003, Pages 4406-4412

  Knauf, Jeffrey A ^a   Kuroda, Hiroaki ^a   Basu, Saswata ^a   Fagin, James A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Differentiation; MEK; RAS; RET PTC; Thyroid

Indexed keywords

CELL PROTEIN; DOXYCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHOLIPASE C; PROTEIN NIS; PROTEIN RET; PROTEIN SHC; PROTEIN TG; PROTEIN TYROSINE KINASE; RAS PROTEIN; THYROTROPIN; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; ONCOPROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE; RET PTC FUSION ONCOPROTEINS, HUMAN; RET-PTC FUSION ONCOPROTEINS, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 DOMAIN CONTAINING, TRANSFORMING PROTEIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; VESICULAR TRANSPORT ADAPTOR PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSCRIPTION; NONHUMAN; ONCOGENE RET; PRIORITY JOURNAL; PROTEIN BINDING; PROTO ONCOGENE; RAT; SIGNAL TRANSDUCTION; THYROID CELL; THYROID PAPILLARY CARCINOMA; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; ONCOGENE RAS; PATHOLOGY; PHYSIOLOGY; THYROID TUMOR;

ANIMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL DIFFERENTIATION; GENES, RAS; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; ONCOGENE PROTEINS, FUSION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTEINS; RATS; SIGNAL TRANSDUCTION; THYROID NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0042303810     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206602     Document Type: Article

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