Metabolism of coumarin by human P450s: A molecular modelling study

Toxicology in Vitro

Volumn 20, Issue 2, 2006, Pages 256-264

  Lewis, David F V ^a   Ito, Yuko ^b   Lake, Brian G ^c  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

^c BIBRA INTERNATIONAL   (United Kingdom)

Author keywords

Coumarin; Metabolism; Molecular modelling; P450

Indexed keywords

AMINO ACID; COUMARIN; CYTOCHROME P450;

AEROBIC METABOLISM; ARTICLE; CRYSTALLOGRAPHY; ENZYME STRUCTURE; MOLECULAR MODEL; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; MODELS, MOLECULAR; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 30644472081     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.08.001     Document Type: Article

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