Modelling human cytochromes P450 involved in drug metabolism from the CYP2C5 crystallographic template

Journal of Inorganic Biochemistry

Volumn 91, Issue 4, 2002, Pages 502-514

  Lewis, David F V ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

CYP2C5 crystal structure; Cytochrome P450; Drug metabolism

Indexed keywords

4 TRIFLUOROMETHYL 7 ETHOXYCOUMARIN; CHLORZOXAZONE; COUMARIN; COUMARIN DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 2C; ISOENZYME; METHOXYRESORUFIN; METHYL GROUP; NIFEDIPINE; OMEPRAZOLE; PROPRANOLOL; RESORUFIN DERIVATIVE; ROSIGLITAZONE; UNCLASSIFIED DRUG; WARFARIN;

CRYSTAL STRUCTURE; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; MOLECULAR MODEL; PROTEIN FAMILY; REVIEW; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0037145065     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(02)00429-4     Document Type: Short Survey

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