In vitro kinetics of coumarin 3,4-epoxidation: Application to species differences in toxicity and carcinogenicity

Toxicological Sciences

Volumn 58, Issue 1, 2000, Pages 23-31

  Born, Stephanie L ^a   Caudill, Douglas ^a   Smith, Bill J ^b   Lehman McKeeman, Lois D ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b PFIZER INC   (United States)

Author keywords

Coumarin; Epoxidation; Human; In vitro; Kinetics; Liver; Mouse; Rat; Toxicity

Indexed keywords

ANTIHYPERTENSIVE AGENT; CEFAZOLIN; COUMARIN; DESMOPRESSIN; DOPAMINE; EPOXIDE; FAMOTIDINE; FENTANYL; FUROSEMIDE; LIDOCAINE; MANNITOL; NITROPRUSSIDE SODIUM; PHENYTOIN; RANITIDINE; UMBELLIFERONE;

ANIMAL MODEL; ARTICLE; CHEMICAL CARCINOGENESIS; CLINICAL ARTICLE; EPOXIDATION; FEMALE; HUMAN; LIVER CANCER; LIVER CARCINOGENESIS; LIVER DISEASE; LIVER MICROSOME; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; RAT; TOXICOKINETICS;

ANIMALIA;

EID: 0033753164     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/58.1.23     Document Type: Article

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