Molecular modelling of the mouse cytochrome P450 CYP2F2 based on the CYP102 crystal structure template and selective CYP2F2 substrate interactions

Drug Metabolism and Drug Interactions

Volumn 19, Issue 2, 2002, Pages 97-113

  Lewis, David F V ^a   Bailey, Paul T ^b   Low, Lawrence K ^b  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b EXXONMOBIL UPSTREAM RESEARCH COMPANY   (United States)

Author keywords

CYP102 structural template; Cytochrome P450; Modelling; Mouse CYP2F2; Xenobiotic metabolism and activation

Indexed keywords

2 (2 HEXADECYL)NAPHTHALENE; 2 ISOPROPYLNAPHTHALENE; CYTOCHROME P450; CYTOCHROME P450 102; CYTOCHROME P450 2F; CYTOCHROME P450 2F2; HEMOPROTEIN; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DNA TEMPLATE; DRUG BINDING; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME METABOLISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; EVALUATION; HYDROGEN BOND; MOLECULAR MODEL; MOLECULAR STABILITY; MOUSE; NONHUMAN; PREDICTION; SEQUENCE HOMOLOGY; STATISTICAL MODEL; STRUCTURE ANALYSIS; XENOBIOTIC METABOLISM;

EID: 0038753033     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: 10.1515/DMDI.2002.19.2.97     Document Type: Article

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