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Volumn 4, Issue 5, 2003, Pages 331-340
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On the estimation of binding affinity (ΔGbind) for human P450 substrates (based on Km and KD values)
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Author keywords
[No Author keywords available]
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Indexed keywords
3,5 DIMETHYL 2 (3 PYRIDYL) 4 THIAZOLIDINONE;
7 ETHOXYCOUMARIN;
AMFEBUTAMONE;
AMITRIPTYLINE;
BENZPHETAMINE;
BUDESONIDE;
COUMARIN DERIVATIVE;
CYTOCHROME P450;
CYTOCHROME P450 1A2;
CYTOCHROME P450 1B1;
CYTOCHROME P450 2A6;
CYTOCHROME P450 2B6;
CYTOCHROME P450 2C19;
CYTOCHROME P450 2C8;
CYTOCHROME P450 2C9;
CYTOCHROME P450 2D6;
CYTOCHROME P450 2E1;
CYTOCHROME P450 3A4;
DIAZEPAM;
ERYTHROMYCIN;
ETHINYLESTRADIOL;
ETOPOSIDE;
MEPHENYTOIN;
MIDAZOLAM;
PHENACETIN;
PHENAZONE;
RESORUFIN DERIVATIVE;
TESTOSTERONE;
UNINDEXED DRUG;
VERAPAMIL;
BINDING AFFINITY;
CALCULATION;
ENDOPLASMIC RETICULUM;
ENERGY;
ENZYME KINETICS;
ENZYME SUBSTRATE;
ENZYME SUBSTRATE COMPLEX;
HUMAN;
HYDROGEN BOND;
LINEAR SYSTEM;
LIPOPHILICITY;
METHODOLOGY;
MOLECULAR MODEL;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
REVIEW;
SEQUENCE ALIGNMENT;
SOLVATION;
THREE DIMENSIONAL IMAGING;
AMINO ACID SEQUENCE;
CYTOCHROME P-450 ENZYME SYSTEM;
HUMANS;
ISOENZYMES;
KINETICS;
MODELS, MOLECULAR;
MOLECULAR SEQUENCE DATA;
PROTEIN BINDING;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
STRUCTURE-ACTIVITY RELATIONSHIP;
SUBSTRATE SPECIFICITY;
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EID: 0142074691
PISSN: 13892002
EISSN: None
Source Type: Journal
DOI: 10.2174/1389200033489343 Document Type: Review |
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Times cited : (27)
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References (12)
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