Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer

International Journal of Radiation Oncology Biology Physics

Volumn 64, Issue 2, 2006, Pages 473-482

  Van Laarhoven, Hanneke W M ^a   Kaanders, Johannes H A M ^a   Lok, Jasper ^a   Peeters, Wenny J M ^a   Rijken, Paul F J W ^a   Wiering, Bastiaan ^a   Ruers, Theo J M ^a   Punt, Cornelis J A ^a   Heerschap, Arend ^a   Van Der Kogel, Albert J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

CA IX; GLUT; Hypoxia; Liver metastases; Pimonidazole

Indexed keywords

CELLS; GLUCOSE; PATIENT TREATMENT; RADIOTHERAPY; TUMORS;

CA-IX; GLUT; HYPOXIA; LIVER METASTASES; PIMONIDAZOLE;

ONCOLOGY;

CARBONATE DEHYDRATASE IX; GLUCOSE TRANSPORTER 1; IDOXURIDINE; PIMONIDAZOLE;

ADULT; AGED; ARTICLE; CANCER SURGERY; CELL PROLIFERATION; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOXIA; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER METASTASIS; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULARIZATION;

ADULT; AGED; CARBONIC ANHYDRASES; CELL HYPOXIA; CELL PROLIFERATION; COLORECTAL NEOPLASMS; FEMALE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; IDOXURIDINE; LIVER NEOPLASMS; MALE; MIDDLE AGED; NITROIMIDAZOLES; TUMOR MARKERS, BIOLOGICAL;

EID: 30544436804     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2005.07.982     Document Type: Article

References (55)

1. V.T. De Vita, S. Hellman Cancer principles and practice oncology 2004 J.B. Lippincott Philadelphia
2. R. Adam, E. Vinet Regional treatment of metastasis Surgery of colorectal liver metastases Ann Oncol 15 Suppl. 4 2004 iv103 iv106
3. C.J. Punt New options and old dilemmas in the treatment of patients with advanced colorectal cancer Ann Oncol 15 2004 1453 1459
4. M. Hockel, C. Knoop, K. Schlenger Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix Radiother Oncol 26 1993 45 50
5. A. Fyles, M. Milosevic, D. Hedley Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer J Clin Oncol 20 2002 680 687
6. J.A. Loncaster, A.L. Harris, S.E. Davidson Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia Correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix Cancer Res 61 2001 6394 6399
7. M. Nordsmark, M. Overgaard, J. Overgaard Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck Radiother Oncol 41 1996 31 39
8. J.H. Kaanders, K.I. Wijffels, H.A. Marres Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer Cancer Res 62 2002 7066 7074
9. M.I. Koukourakis, A. Giatromanolaki, E. Sivridis Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer Int J Radiat Oncol Biol Phys 53 2002 1192 1202
10. J.A. Raleigh, S.C. Chou, G.E. Arteel Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors Radiat Res 151 1999 580 589
11. R. Airley, J. Loncaster, S. Davidson Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix Clin Cancer Res 7 2001 928 934
12. R.E. Airley, J. Loncaster, J.A. Raleigh GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix Relationship to pimonidazole binding Int J Cancer 104 2003 85 91
13. S.K. Chia, C.C. Wykoff, P.H. Watson Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma J Clin Oncol 19 2001 3660 3668
14. A.C. Clavo, R.S. Brown, R.L. Wahl Fluorodeoxyglucose uptake in human cancer cell lines is increased by hypoxia J Nucl Med 36 1995 1625 1632
15. M.W. Pedersen, S. Holm, E.L. Lund Coregulation of glucose uptake and vascular endothelial growth factor (VEGF) in two small-cell lung cancer (SCLC) sublines in vivo and in vitro Neoplasia 3 2001 80 87
16. I. Stein, M. Neeman, D. Shweiki Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes Mol Cell Biol 15 1995 5363 5368
17. C. Chen, N. Pore, A. Behrooz Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia J Biol Chem 276 2001 9519 9525
18. R.S. Brown, R.L. Wahl Overexpression of Glut-1 glucose transporter in human breast cancer. An immunohistochemical study Cancer 72 1993 2979 2985
19. B.M. Burt, J.L. Humm, D.A. Kooby Using positron emission tomography with [(18)F]FDG to predict tumor behavior in experimental colorectal cancer Neoplasia 3 2001 189 195
20. C.C. Wykoff, N.J. Beasley, P.H. Watson Hypoxia-inducible expression of tumor-associated carbonic anhydrases Cancer Res 60 2000 7075 7083
21. K.J. Turner, J.P. Crew, C.C. Wykoff The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs. invasive bladder cancer Br J Cancer 86 2002 1276 1282
22. A. Lal, H. Peters, B. St Croix Transcriptional response to hypoxia in human tumors J Natl Cancer Inst 93 2001 1337 1343
23. R.E. Durand, J.A. Raleigh Identification of nonproliferating but viable hypoxic tumor cells in vivo Cancer Res 58 1998 3547 3550
24. G.E. Arteel, R.G. Thurman, J.M. Yates Evidence that hypoxia markers detect oxygen gradients in liver Pimonidazole and retrograde perfusion of rat liver Br J Cancer 72 1995 889 895
25. J.A. Raleigh, A.J. Franko, E.O. Treiber Covalent binding of a fluorinated 2-nitroimidazole to EMT-6 tumors in Balb/C mice Detection by F-19 nuclear magnetic resonance at 2.35 T Int J Radiat Oncol Biol Phys 12 1986 1243 1245
26. J.A. Raleigh, G.G. Miller, A.J. Franko Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours Br J Cancer 56 1987 395 400
27. P.F. Rijken, H.J. Bernsen, A.J. van der Kogel Application of an image analysis system to the quantitation of tumor perfusion and vascularity in human glioma xenografts Microvasc Res 50 1995 141 153
28. J. Bussink, J.H. Kaanders, P.F. Rijken Multiparameter analysis of vasculature, perfusion, and proliferation in human tumour xenografts Br J Cancer 77 1998 57 64
29. P.F. Rijken, H.J. Bernsen, J.P. Peters Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft A quantitative multi-parameter analysis Int J Radiat Oncol Biol Phys 48 2000 571 582
30. P. Vaupel, A. Mayer, M. Hockel Tumor hypoxia and malignant progression Methods Enzymol 381 2004 335 354
31. J. Bussink, J.H. Kaanders, A.J. van der Kogel Tumor hypoxia at the micro-regional level Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers Radiother Oncol 67 2003 3 15
32. M. Nordsmark, J. Loncaster, C. Aquino-Parsons Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas Radiother Oncol 67 2003 35 44
33. M. Nordsmark, J. Loncaster, S.C. Chou Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma Int J Radiat Oncol Biol Phys 49 2001 581 586
34. S.M. Evans, K.D. Judy, I. Dunphy Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding Cancer Res 64 2004 1886 1892
35. P.L. Olive, C. Aquino-Parsons, S.H. MacPhail Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer Cancer Res 61 2001 8924 8929
36. A.S. Ljungkvist, J. Bussink, J.H. Kaanders Hypoxic cell turnover in different solid tumor lines Int J Radiat Oncol Biol Phys 62 2005 1157 1168
37. K.I. Wijffels, J.H. Kaanders, P.F. Rijken Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas Br J Cancer 83 2000 674 683
38. A.S. Ljungkvist, J. Bussink, P.F. Rijken Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas Int J Radiat Oncol Biol Phys 54 2002 215 228
39. R.H. Thomlinson, L.H. Gray The histological structure of some human lung cancers and the possible implications for radiotherapy Br J Cancer 9 1955 539 549
40. J.M. Brown Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation Br J Radiol 52 1979 650 656
41. P.J. Hoskin, A. Sibtain, F.M. Daley GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer Relationship with vascularity and proliferation as predictors of outcome of ARCON Br J Cancer 89 2003 1290 1297
42. D. Hedley, M. Pintilie, J. Woo Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas Clin Cancer Res 9 2003 5666 5674
43. G.L. Semenza Expression of hypoxia-inducible factor 1 Mechanisms and consequences Biochem Pharmacol 59 2000 47 53
44. R.A. Medina, M.A. Maria, V.J. Carlos Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells J Endocrinol 182 2004 467 478
45. J. Hakimian, F. Ismail-Beigi Enhancement of glucose transport in clone 9 cells by exposure to alkaline pH Studies on potential mechanisms J Membr Biol 120 1991 29 39
46. A. Klip, T. Tsakiridis, A. Marette Regulation of expression of glucose transporters by glucose A review of studies in vivo and in cell cultures FASEB J 8 1994 43 53
47. S. Ivanov, S.Y. Liao, A. Ivanova Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer Am J Pathol 158 2001 905 919
48. O. Warburg On the origin of cancer cells Science 123 1956 309 314
49. J.R. Griffiths, D.J. McIntyre, F.A. Howe Why are cancers acidic? A carrier-mediated diffusion model for H+ transport in the interstitial fluid Novartis Found Symp 240 2001 46 62
50. I.J. Hoogsteen, H.A.M. Marres, K.I. Wijffels Co-localization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma Clin Cancer Res 11 2005 97 106
51. R.S. Haber, A. Rathan, K.R. Weiser GLUT1 glucose transporter expression in colorectal carcinoma A marker for poor prognosis Cancer 83 1998 34 40
52. R. Cooper, S. Sarioglu, S. Sokmen Glucose transporter-1 (GLUT-1) A potential marker of prognosis in rectal carcinoma? Br J Cancer 89 2003 870 876
53. J. Saarnio, S. Parkkila, A.K. Parkkila Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation Am J Pathol 153 1998 279 285
54. A.J. Kivela, J. Saarnio, T.J. Karttunen Differential expression of cytoplasmic carbonic anhydrases, CA I and II, and membrane-associated isozymes, CA IX and XII, in normal mucosa of large intestine and in colorectal tumors Dig Dis Sci 46 2001 2179 2186
55. A. Becker, G. Hansgen, M. Bloching Oxygenation of squamous cell carcinoma of the head and neck Comparison of primary tumors, neck node metastases, and normal tissue Int J Radiat Oncol Biol Phys 42 1998 35 41