메뉴 건너뛰기




Volumn 15, Issue 10, 2004, Pages 1453-1459

New options and old dilemmas in the treatment of patients with advanced colorectal cancer

Author keywords

Bevacizumab; Capecitabine; Cetuximab; Colorectal cancer; Irinotecan; Oxaliplatin

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CELECOXIB; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; UFT; VASCULOTROPIN;

EID: 6944234851     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/annonc/mdh383     Document Type: Review
Times cited : (98)

References (50)
  • 1
    • 17744418861 scopus 로고    scopus 로고
    • Randomized phase III study of high-dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer
    • European Organization of Research and Treatment of Cancer Gastrointestinal Group Study 40952
    • Köhne C-H, Wils J, Lorenz M et al. Randomized phase III study of high-dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer: European Organization of Research and Treatment of Cancer Gastrointestinal Group Study 40952. J Clin Oncol 2003; 21: 3721-3728.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3721-3728
    • Köhne, C.-H.1    Wils, J.2    Lorenz, M.3
  • 2
    • 0041055512 scopus 로고    scopus 로고
    • Randomised multicentre trial of chronotherapy with oxatiplatin, fluorouracil, and folinic acid in metastatic colorectal cancer
    • International Organization for Cancer Chronotherapy
    • Levi F, Zidani R, Misset JL. Randomised multicentre trial of chronotherapy with oxatiplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. International Organization for Cancer Chronotherapy. Lancet 1997; 350: 681-686.
    • (1997) Lancet , vol.350 , pp. 681-686
    • Levi, F.1    Zidani, R.2    Misset, J.L.3
  • 3
    • 0028219974 scopus 로고
    • Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer
    • Advanced Colorectal Cancer Meta-Analysis Project
    • Advanced Colorectal Cancer Meta-Analysis Project. Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. J Clin Oncol 1994; 12: 960-969.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 960-969
  • 4
    • 0036231431 scopus 로고    scopus 로고
    • Integrated analysis of overall survival in two randomised studies comparing 5-fluorouracil/leucovorin with or without trimetrexate in advanced colorectal cancer
    • Punt CJA, Blanke CD, Zhang J, Hammershaimb L. Integrated analysis of overall survival in two randomised studies comparing 5-fluorouracil/leucovorin with or without trimetrexate in advanced colorectal cancer. Ann Oncol 2002; 13: 92-94.
    • (2002) Ann. Oncol. , vol.13 , pp. 92-94
    • Punt, C.J.A.1    Blanke, C.D.2    Zhang, J.3    Hammershaimb, L.4
  • 5
    • 0026721532 scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • Advanced Colorectal Cancer Meta-Analysis Project
    • Advanced Colorectal Cancer Meta-Analysis Project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J Clin Oncol 1992; 10: 896-903.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 896-903
  • 6
    • 0026762968 scopus 로고
    • Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: A randomized trial
    • The Nordic Gastrointestinal Tumor Adjuvant Therapy Group
    • The Nordic Gastrointestinal Tumor Adjuvant Therapy Group. Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: a randomized trial. J Clin Oncol 1992; 10: 904-911.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 904-911
  • 7
    • 0000598052 scopus 로고    scopus 로고
    • A meta-analysis of two randomized trials of early chemotherapy in asymptomatic metastatic colorectal cancer
    • (Abstr 526)
    • Ackland SP, Moore M, Jones M et al. A meta-analysis of two randomized trials of early chemotherapy in asymptomatic metastatic colorectal cancer. Proc Am Soc Clin Oncol 2001; 20: 132a (Abstr 526).
    • (2001) Proc. Am. Soc. Clin. Oncol. , vol.20
    • Ackland, S.P.1    Moore, M.2    Jones, M.3
  • 8
    • 0037425721 scopus 로고    scopus 로고
    • Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: A multicenter randomised trial
    • Maughan TS, James RD, Kerr DJ et al. Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicenter randomised trial. Lancet 2003; 361: 457-464.
    • (2003) Lancet , vol.361 , pp. 457-464
    • Maughan, T.S.1    James, R.D.2    Kerr, D.J.3
  • 9
    • 0042213490 scopus 로고    scopus 로고
    • FOLFOX7 compared to FOLFOX4. Preliminary results of the randomized optimox study
    • (Abstr 1016)
    • André T, Figer A, Cervantes A et al. FOLFOX7 compared to FOLFOX4. Preliminary results of the randomized optimox study. Proc Am Soc Clin Oncol 2003; 22: 253 (Abstr 1016).
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , pp. 253
    • André, T.1    Figer, A.2    Cervantes, A.3
  • 10
    • 0035871538 scopus 로고    scopus 로고
    • Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study
    • Hoff PM, Ansari R, Batist G et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol 2001; 19: 2282-2292.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 2282-2292
    • Hoff, P.M.1    Ansari, R.2    Batist, G.3
  • 11
    • 0035503151 scopus 로고    scopus 로고
    • Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
    • Van Cutsem E, Twelves C, Cassidy J et al. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol 2001; 19: 4097-4106.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 4097-4106
    • Van Cutsem, E.1    Twelves, C.2    Cassidy, J.3
  • 12
    • 0036731818 scopus 로고    scopus 로고
    • Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Douillard JY, Hoff PM, Skillings JR et al. Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2002; 20: 3605-3616.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3605-3616
    • Douillard, J.Y.1    Hoff, P.M.2    Skillings, J.R.3
  • 13
    • 0036727089 scopus 로고    scopus 로고
    • Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Carmichael J, Popiela T, Radstone D et al. Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2002; 203: 3617-3627.
    • (2002) J. Clin. Oncol. , vol.203 , pp. 3617-3627
    • Carmichael, J.1    Popiela, T.2    Radstone, D.3
  • 14
    • 11144354462 scopus 로고    scopus 로고
    • Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: Integrated efficacy data and novel analyses from two large, randomized, phase III trials
    • Van Cutsem E, Hoff PM, Harper P et al. Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomized, phase III trials. Br J Cancer 2004; 90: 1190-1197.
    • (2004) Br. J. Cancer. , vol.90 , pp. 1190-1197
    • Van Cutsem, E.1    Hoff, P.M.2    Harper, P.3
  • 15
    • 0036235128 scopus 로고    scopus 로고
    • First-line oral capecitabine therapy in metastatic colorectal cancer: A favorable safety profile compared with intravenous 5- fluorouracil/leucovorin
    • Cassidy J, Twelves C, Van Cutsem E et al. First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5- fluorouracil/leucovorin. Ann Oncol 2002; 13: 566-575.
    • (2002) Ann. Oncol. , vol.13 , pp. 566-575
    • Cassidy, J.1    Twelves, C.2    Van Cutsem, E.3
  • 16
    • 0036159485 scopus 로고    scopus 로고
    • Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and lencovorin: A randomized crossover trial in advanced colorectal cancer
    • Borner MM, Schöffski P, de Wit R et al. Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and lencovorin: a randomized crossover trial in advanced colorectal cancer. Eur J Cancer 2002; 38: 349-358.
    • (2002) Eur. J. Cancer , vol.38 , pp. 349-358
    • Borner, M.M.1    Schöffski, P.2    de Wit, R.3
  • 18
    • 0025053811 scopus 로고
    • Possible cardiotoxicity induced by orally administered fluoropyrimidines
    • Camps C, Godes M, Soler JJ. Possible cardiotoxicity induced by orally administered fluoropyrimidines. An Med Interna 1990; 7: 525-527.
    • (1990) An. Med. Interna. , vol.7 , pp. 525-527
    • Camps, C.1    Godes, M.2    Soler, J.J.3
  • 19
    • 0034016343 scopus 로고    scopus 로고
    • Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: Results of a randomized phase II study
    • Van Cutsem E, Findlay M, Osterwalder B et al. Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study. J Clin Oncol 2000; 18: 1337-1345.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1337-1345
    • Van Cutsem, E.1    Findlay, M.2    Osterwalder, B.3
  • 20
    • 0028099423 scopus 로고
    • Phase II study of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal cancer
    • Pazdur R, Passere Y, Rhodes V et al. Phase II study of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal cancer. J Clin Oncol 1994; 12: 2296-2300.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2296-2300
    • Pazdur, R.1    Passere, Y.2    Rhodes, V.3
  • 21
    • 0346984104 scopus 로고    scopus 로고
    • Combination of irinotecan and capecitabine as first-line treatment in advanced colorectal cancer (ACC): Results of a phase II trial
    • (Abstr 277)
    • Punt CJA, Nortier JW, ten Bokkel Huinink WW et al. Combination of irinotecan and capecitabine as first-line treatment in advanced colorectal cancer (ACC): results of a phase II trial. Eur J Cancer 2003; 1 (Suppl 5): S85 (Abstr 277).
    • (2003) Eur. J. Cancer , vol.1 , Issue.SUPPL. 5
    • Punt, C.J.A.1    Nortier, J.W.2    ten Bokkel Huinink, W.W.3
  • 22
    • 0141725528 scopus 로고    scopus 로고
    • Phase II study of capecitabine and oxaliplatin as first-line treatment in advanced colorectal cancer
    • Zeuli M, Nardoni C, Pino MS et al. Phase II study of capecitabine and oxaliplatin as first-line treatment in advanced colorectal cancer. Ann Oncol 2003; 14: 1378-1382.
    • (2003) Ann. Oncol. , vol.14 , pp. 1378-1382
    • Zeuli, M.1    Nardoni, C.2    Pino, M.S.3
  • 23
    • 0036533777 scopus 로고    scopus 로고
    • Phase-II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer
    • Borner MM, Dietrich D, Stupp R et al. Phase-II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer. J Clin Oncol 2002; 20: 1759-1766.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1759-1766
    • Borner, M.M.1    Dietrich, D.2    Stupp, R.3
  • 24
    • 2142730276 scopus 로고    scopus 로고
    • Capecitabine plus irinotecan (CAPIRI) vs capecitabine plus oxaliplatin (CAPOX) as first-line therapy of advanced colorectal cancer (ACRC): Updated results of a randomized phase II trial
    • (Abstr 295)
    • Grothey A, Jordan K, Kellner O et al. Capecitabine plus irinotecan (CAPIRI) vs capecitabine plus oxaliplatin (CAPOX) as first-line therapy of advanced colorectal cancer (ACRC): updated results of a randomized phase II trial. Eur J Cancer 2003; S90 (Suppl 5): S90 (Abstr 295).
    • (2003) Eur. J. Cancer , vol.S90 , Issue.SUPPL. 5
    • Grothey, A.1    Jordan, K.2    Kellner, O.3
  • 25
    • 10744229113 scopus 로고    scopus 로고
    • UFT/leucovorin and oxaliplatin alternated with UFT/leucovorin and irinotecan in metastatic colorectal cancer
    • Petrioli R, Sabatino M, Fiaschi AI et al. UFT/leucovorin and oxaliplatin alternated with UFT/leucovorin and irinotecan in metastatic colorectal cancer. Br J Cancer 2004; 90: 306-309.
    • (2004) Br. J. Cancer , vol.90 , pp. 306-309
    • Petrioli, R.1    Sabatino, M.2    Fiaschi, A.I.3
  • 26
    • 0036787579 scopus 로고    scopus 로고
    • Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer
    • Dunst J, Reese T, Sutter T et al. Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. J Clin Oncol 2002; 20: 3983-3991.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3983-3991
    • Dunst, J.1    Reese, T.2    Sutter, T.3
  • 27
    • 0041912759 scopus 로고    scopus 로고
    • Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer
    • Rodel G, Grabenbauer GG, Papadopoulos T et al. Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer. J Clin Oncol 2003; 21: 3098-3104.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3098-3104
    • Rodel, G.1    Grabenbauer, G.G.2    Papadopoulos, T.3
  • 28
    • 0032585232 scopus 로고    scopus 로고
    • Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
    • Cunningham D, Pyrhönen S, James RD et al. Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 1998; 352: 1413-1418.
    • (1998) Lancet , vol.352 , pp. 1413-1418
    • Cunningham, D.1    Pyrhönen, S.2    James, R.D.3
  • 29
    • 0037531121 scopus 로고    scopus 로고
    • Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: Interim results of a phase III trial
    • Rothenberg ML, Oza AM, Bigelow RH et al. Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial. J Clin Oncol 2003; 21: 2059-2069.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2059-2069
    • Rothenberg, M.L.1    Oza, A.M.2    Bigelow, R.H.3
  • 30
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
    • Douillard JY, Cunningham D, Roth AD et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000; 355: 1041-1047.
    • (2000) Lancet , vol.355 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3
  • 31
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
    • Irinotecan Study Group
    • Saltz LB, Cox JV, Blanke C et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343: 905-914.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 32
    • 0033807092 scopus 로고    scopus 로고
    • 'Hold the Mayo': Solid facts or pulp fiction?
    • Punt CJA. 'Hold the Mayo': solid facts or pulp fiction? Ann Oncol 2000; 11: 919-920.
    • (2000) Ann. Oncol. , vol.11 , pp. 919-920
    • Punt, C.J.A.1
  • 33
    • 2342443299 scopus 로고    scopus 로고
    • Is overall survival a realistic primary end point in advanced colorectal cancer studies? A critical assessment based on four clinical trials comparing fluorouracil plus leucovorin with the same treatment combined either with oxaliplatin or with CPT-11
    • Di Leo A, Buyse M, Bleiberg H. Is overall survival a realistic primary end point in advanced colorectal cancer studies? A critical assessment based on four clinical trials comparing fluorouracil plus leucovorin with the same treatment combined either with oxaliplatin or with CPT-11. Ann Oncol 2004; 15: 545-549.
    • (2004) Ann. Oncol. , vol.15 , pp. 545-549
    • Di Leo, A.1    Buyse, M.2    Bleiberg, H.3
  • 34
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004; 22: 23-30.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3
  • 35
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reversed sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, André T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reversed sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22: 229-237.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 229-237
    • Tournigand, C.1    André, T.2    Achille, E.3
  • 36
    • 0036928276 scopus 로고    scopus 로고
    • Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: A dose-finding study in patients with advanced gastrointestinal malignancies
    • Comella P, Casaretti R, De Rosa V et al. Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: a dose-finding study in patients with advanced gastrointestinal malignancies. Ann Oncol 2002; 13: 1874-1881.
    • (2002) Ann. Oncol. , vol.13 , pp. 1874-1881
    • Comella, P.1    Casaretti, R.2    De Rosa, V.3
  • 37
    • 12244287645 scopus 로고    scopus 로고
    • An open phase I study assessing the feasibility of the triple combination: Oxaliplatin plus irinotecan plus leucovorin-5-fluorouracil every 2 weeks in patients with advanced solid tumors
    • Ychou M, Conroy T, Seitz JF et al. An open phase I study assessing the feasibility of the triple combination: oxaliplatin plus irinotecan plus leucovorin-5-fluorouracil every 2 weeks in patients with advanced solid tumors. Ann Oncol 2003; 14: 481-489.
    • (2003) Ann. Oncol. , vol.14 , pp. 481-489
    • Ychou, M.1    Conroy, T.2    Seitz, J.F.3
  • 38
    • 0142087632 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of two different schedules of oxaliplatin, irinotecan, fluorouracil, and leucovorin in patients with solid tumors
    • Goetz MP, Erlichman C, Windebank AJ et al. Phase I and pharmacokinetic study of two different schedules of oxaliplatin, irinotecan, fluorouracil, and leucovorin in patients with solid tumors. J Clin Oncol 2003; 21: 3761-3769.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3761-3769
    • Goetz, M.P.1    Erlichman, C.2    Windebank, A.J.3
  • 39
    • 0142119280 scopus 로고    scopus 로고
    • Therapeutic strategies for metastatic colorectal cancer: Simultaneous, sequential, or specific?
    • Rothenberg ML, Berlin JD. Therapeutic strategies for metastatic colorectal cancer: simultaneous, sequential, or specific? J Clin Oncol 2003; 21: 3716-3717.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3716-3717
    • Rothenberg, M.L.1    Berlin, J.D.2
  • 40
    • 2142703727 scopus 로고    scopus 로고
    • Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
    • Grothey A, Sargent D, Goldberg RM, Schmoll HJ. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol 2004; 22: 1209-1214.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1209-1214
    • Grothey, A.1    Sargent, D.2    Goldberg, R.M.3    Schmoll, H.J.4
  • 41
    • 0141890141 scopus 로고    scopus 로고
    • Pharmacogenomics in colorectal cancer
    • Lenz HJ. Pharmacogenomics in colorectal cancer. Semin Oncol 2003; 30 (4 Suppl 15): 47-53.
    • (2003) Semin. Oncol. , vol.30 , Issue.4 SUPPL. 15 , pp. 47-53
    • Lenz, H.J.1
  • 42
    • 0036230263 scopus 로고    scopus 로고
    • Treatment of liver metastases, an update on the possibilities and results
    • Ruers T, Bleichrodt RP. Treatment of liver metastases, an update on the possibilities and results. Eur J Cancer 2002; 38: 1023-1033.
    • (2002) Eur. J. Cancer , vol.38 , pp. 1023-1033
    • Ruers, T.1    Bleichrodt, R.P.2
  • 43
    • 0032125444 scopus 로고    scopus 로고
    • Surgery for recurrent colon cancer: Strategies for identifying resectable recurrence and success rates after resection
    • Goldberg RM, Fleming TR, Tangen CM et al. Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Ann Intern Med 1998; 129: 27-35.
    • (1998) Ann. Intern. Med. , vol.129 , pp. 27-35
    • Goldberg, R.M.1    Fleming, T.R.2    Tangen, C.M.3
  • 44
    • 0038600610 scopus 로고    scopus 로고
    • Chemotherapy and surgery: New perspectives on the treatment of unresectable liver metastases
    • Adam R. Chemotherapy and surgery: new perspectives on the treatment of unresectable liver metastases. Ann Oncol 2003; 14 (Supp] 2): ii13-ii16.
    • (2003) Ann. Oncol. , vol.14 , Issue.SUPPL. 2
    • Adam, R.1
  • 45
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ Sr et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004; 22: 1201-1208.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr., P.J.3
  • 46
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351: 337-345.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 47
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 48
    • 0034596549 scopus 로고    scopus 로고
    • Palliative chemotherapy for advanced colorectal cancer: Systematic review and meta-analysis
    • Colorectal Cancer Collaborative Group
    • Colorectal Cancer Collaborative Group. Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis. BMJ 2000; 321: 531-535.
    • (2000) BMJ , vol.321 , pp. 531-535
  • 49
    • 0038167780 scopus 로고    scopus 로고
    • Who's afraid of the European Clinical Trials Directive?
    • Editorial
    • Editorial. Who's afraid of the European Clinical Trials Directive? Lancet 2003; 361: 2167.
    • (2003) Lancet , vol.361 , pp. 2167
  • 50
    • 0042967720 scopus 로고    scopus 로고
    • European Organisation for Research and Treatment of Cancer's point of view
    • Meunier F, Lacombe D. European Organisation for Research and Treatment of Cancer's point of view. Lancet 2003; 362: 663.
    • (2003) Lancet , vol.362 , pp. 663
    • Meunier, F.1    Lacombe, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.