메뉴 건너뛰기




Volumn 29, Issue 8, 2004, Pages 1529-1536

Molecular basis of anti-apoptotic effect of immunophilin ligands on hydrogen peroxide-induced apoptosis in human glioma cells

Author keywords

Antiapoptosis; BDNF; caspase; FK506; GDNF; glutathione; GPI1046; neurotrophic factor; oxidative stress; V10367

Indexed keywords

1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (3 PYRIDYL)PROPYL ESTER; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; GLUTATHIONE; HYDROGEN PEROXIDE; IMMUNOPHILIN; LIGAND; MESSENGER RNA; NEUROTROPHIC FACTOR; PROTEIN P53; TACROLIMUS; UNCLASSIFIED DRUG; V 10367;

EID: 3042739759     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000029565.92587.25     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 0027158431 scopus 로고
    • The preventive effect of cyclosporin A, an immunosuppressant, on the late onset reduction of muscarinic acetylcholine receptors in gerbil hippocampus after transient forebrain ischemia
    • Ogawa, N., Tanaka, K., Kondo, Y., Asanuma, M., Mizukawa, K., and Mori, A. 1993. The preventive effect of cyclosporin A, an immunosuppressant, on the late onset reduction of muscarinic acetylcholine receptors in gerbil hippocampus after transient forebrain ischemia. Neurosci. Lett. 152:173-176.
    • (1993) Neurosci. Lett. , vol.152 , pp. 173-176
    • Ogawa, N.1    Tanaka, K.2    Kondo, Y.3    Asanuma, M.4    Mizukawa, K.5    Mori, A.6
  • 2
    • 0027937489 scopus 로고
    • Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischemia
    • Sharkey, J. and Butcher, S. P. 1994. Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischemia. Nature 371:336-339.
    • (1994) Nature , vol.371 , pp. 336-339
    • Sharkey, J.1    Butcher, S.P.2
  • 3
    • 0031309575 scopus 로고    scopus 로고
    • FK506 and the role of immunophilins in nerve regeneration
    • Gold, B. G. 1997. FK506 and the role of immunophilins in nerve regeneration. Mol. Neurobiol. 15:285-306.
    • (1997) Mol. Neurobiol. , vol.15 , pp. 285-306
    • Gold, B.G.1
  • 4
    • 0031214457 scopus 로고    scopus 로고
    • Cyclosporin A attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine
    • Matsuura, K., Makino, H., and Ogawa, N. 1997. Cyclosporin A attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine. Exp. Neurol. 146:526-535.
    • (1997) Exp. Neurol. , vol.146 , pp. 526-535
    • Matsuura, K.1    Makino, H.2    Ogawa, N.3
  • 5
    • 0030975605 scopus 로고    scopus 로고
    • Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A
    • Steiner, J. P., Connolly, M. A., Valentine, H. L., Hamilton, G. S., Hester, L., and Snyder, S. H. 1997. Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nature Med. 3:421-428.
    • (1997) Nature Med. , vol.3 , pp. 421-428
    • Steiner, J.P.1    Connolly, M.A.2    Valentine, H.L.3    Hamilton, G.S.4    Hester, L.5    Snyder, S.H.6
  • 9
    • 0031660913 scopus 로고    scopus 로고
    • A novel immunophilin ligands: Distinct branching effects on dopaminergic neurons in culture and neurotrophic actions after oral administration in an animal model of Parkinson's disease
    • Costantini, L. C., Chaturvedi, P., Armistead, D. M., McCaffrey, P. G., Deacon, T. W., and Isacson, O. 1998. A novel immunophilin ligands: distinct branching effects on dopaminergic neurons in culture and neurotrophic actions after oral administration in an animal model of Parkinson's disease. Neurobiol. Dis. 5:97-108.
    • (1998) Neurobiol. Dis. , vol.5 , pp. 97-108
    • Costantini, L.C.1    Chaturvedi, P.2    Armistead, D.M.3    McCaffrey, P.G.4    Deacon, T.W.5    Isacson, O.6
  • 10
    • 0033581334 scopus 로고    scopus 로고
    • Systemic treatment with GPI 1046 improves spatial memory and reverses cholinergic neuron atrophy in the medial septal nucleus of aged mice
    • Sauer, H., Francis, J. M., Jiang, H., Hamilton, G. S., and Steiner, J. P. 1999. Systemic treatment with GPI 1046 improves spatial memory and reverses cholinergic neuron atrophy in the medial septal nucleus of aged mice. Brain Res. 842:109-118.
    • (1999) Brain Res. , vol.842 , pp. 109-118
    • Sauer, H.1    Francis, J.M.2    Jiang, H.3    Hamilton, G.S.4    Steiner, J.P.5
  • 11
    • 0033819704 scopus 로고    scopus 로고
    • Neuroimmunophilin ligands: Evaluation of their therapeutic potential for the treatment of neurological disorders
    • Gold, B. G. 2000. Neuroimmunophilin ligands: evaluation of their therapeutic potential for the treatment of neurological disorders. Exp. Opin. Invest. Drugs 9:2331-2342.
    • (2000) Exp. Opin. Invest. Drugs , vol.9 , pp. 2331-2342
    • Gold, B.G.1
  • 12
    • 0033963487 scopus 로고    scopus 로고
    • Immunophilin ligands as a novel treatment for neurological disorders
    • Herdegen, T., Fischer, G., and Gold, B. G. 2000. Immunophilin ligands as a novel treatment for neurological disorders. TiPS 21:3-5.
    • (2000) TiPS , vol.21 , pp. 3-5
    • Herdegen, T.1    Fischer, G.2    Gold, B.G.3
  • 13
    • 0034540749 scopus 로고    scopus 로고
    • 2-induced apoptotic cell death by increasing glutathione levels in Neuro 2A neuroblastoma cells
    • 2-induced apoptotic cell death by increasing glutathione levels in Neuro 2A neuroblastoma cells. Acta Med. Okayama 54:275-280.
    • (2000) Acta Med. Okayama , vol.54 , pp. 275-280
    • Tanaka, K.1    Fujita, N.2    Asanuma, M.3    Ogawa, N.4
  • 14
    • 0035910371 scopus 로고    scopus 로고
    • 2-induced cell damage by increasing glutathione levels in NG108-15 cells
    • 2-induced cell damage by increasing glutathione levels in NG108-15 cells. Brain Res. 889:236-239.
    • (2001) Brain Res. , vol.889 , pp. 236-239
    • Tanaka, K.1    Fujita, N.2    Yoshioka, M.3    Ogawa, N.4
  • 15
    • 0036497934 scopus 로고    scopus 로고
    • Effects of immunophilin ligands on hydrogen peroxide-induced apoptosis in C6 glioma cells
    • Tanaka, K., Fujita, N., Higashi, Y., and Ogawa, N. 2002. Effects of immunophilin ligands on hydrogen peroxide-induced apoptosis in C6 glioma cells. Synapse 43:219-222.
    • (2002) Synapse , vol.43 , pp. 219-222
    • Tanaka, K.1    Fujita, N.2    Higashi, Y.3    Ogawa, N.4
  • 16
    • 0037087049 scopus 로고    scopus 로고
    • GPI1046 prevents dopaminergic dysfunction by activating glutathione system in the mouse striatum
    • Tanaka, K., Yoshioka, M., Miyazaki, I., Fujita, N., and Ogawa, N. 2002. GPI1046 prevents dopaminergic dysfunction by activating glutathione system in the mouse striatum. Neurosci. Lett. 321:45-48.
    • (2002) Neurosci. Lett. , vol.321 , pp. 45-48
    • Tanaka, K.1    Yoshioka, M.2    Miyazaki, I.3    Fujita, N.4    Ogawa, N.5
  • 17
    • 0026754574 scopus 로고
    • Reactive oxygen species in the central nervous system
    • Halliwell, B. 1992. Reactive oxygen species in the central nervous system. J. Neurochem. 59:1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 18
    • 0032973861 scopus 로고    scopus 로고
    • Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis
    • Iwata-Ichikawa, E., Kondo, Y., Miyazaki, I., Asanuma, M., and Ogawa, N. 1999. Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis. J. Neurochem. 72:2334-2344.
    • (1999) J. Neurochem. , vol.72 , pp. 2334-2344
    • Iwata-Ichikawa, E.1    Kondo, Y.2    Miyazaki, I.3    Asanuma, M.4    Ogawa, N.5
  • 19
    • 0036830462 scopus 로고    scopus 로고
    • The p53-activated gene, PAG608, requires a zinc finger domain for nuclear localization and oxidative stress-induced apoptosis
    • Higashi, Y., Asanuma, M., Miyazaki, I., Haque, M. E., Fujita, N., Tanaka, K., and Ogawa, N. 2002. The p53-activated gene, PAG608, requires a zinc finger domain for nuclear localization and oxidative stress-induced apoptosis. J. Biol. Chem. 277:42224-42232.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42224-42232
    • Higashi, Y.1    Asanuma, M.2    Miyazaki, I.3    Haque, M.E.4    Fujita, N.5    Tanaka, K.6    Ogawa, N.7
  • 20
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze, F. 1969. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27:502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 21
    • 0035007296 scopus 로고    scopus 로고
    • Molecular mechanism in activation of glutathione system by ropinirole, a selective dopamine D2 agonist
    • Tanaka, K., Miyazaki, I., Fujita, N., Haque, M. E., Asanuma, M., and Ogawa, N. 2001. Molecular mechanism in activation of glutathione system by ropinirole, a selective dopamine D2 agonist. Neurochem. Res. 26:31-36.
    • (2001) Neurochem. Res. , vol.26 , pp. 31-36
    • Tanaka, K.1    Miyazaki, I.2    Fujita, N.3    Haque, M.E.4    Asanuma, M.5    Ogawa, N.6
  • 22
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen, D. E. 1995. Neural apoptosis. Ann. Neurol. 38:839-851.
    • (1995) Ann. Neurol. , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 23
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner, M. O. 2000. The biochemistry of apoptosis. Nature 407:770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 24
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer, G. and Reed, J. C. 2000. Mitochondrial control of cell death. Nat. Med. 6:513-519.
    • (2000) Nat. Med. , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 25
    • 0035146929 scopus 로고    scopus 로고
    • Life-or death decisions by the Bcl-2 protein family
    • Adams, J. M. and Cory, S. 2001. Life-or death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26:61-66.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 61-66
    • Adams, J.M.1    Cory, S.2
  • 26
    • 0036479054 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in acute neurodegeneration
    • Friberg, H. and Wieloch, T. 2002. Mitochondrial permeability transition in acute neurodegeneration. Biochimie 84:241-250.
    • (2002) Biochimie , vol.84 , pp. 241-250
    • Friberg, H.1    Wieloch, T.2
  • 27
    • 0033525375 scopus 로고    scopus 로고
    • Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin
    • Uberti, D., Yavin, E., Gil, S., Ayasola, K. R., Goldfinger, N., and Rotter, V. 1999. Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin. Mol. Brain Res. 65:167-175.
    • (1999) Mol. Brain Res. , vol.65 , pp. 167-175
    • Uberti, D.1    Yavin, E.2    Gil, S.3    Ayasola, K.R.4    Goldfinger, N.5    Rotter, V.6
  • 28
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra, J., Samali, A., and Orrenius, S. 2000. Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29:323-333.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 323-333
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 29
    • 0031754828 scopus 로고    scopus 로고
    • Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis
    • Peter, M. E. and Krammer, P. H. 1998. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis. Curr. Opin. Immunol. 10:545-551.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 545-551
    • Peter, M.E.1    Krammer, P.H.2
  • 30
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou, H., Li, Y., Liu, X., and Wang, X. 1999. An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274:11549-11556.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4
  • 31
    • 0033580926 scopus 로고    scopus 로고
    • Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
    • Saleh, A., Srinivasula, S. M., Acharya, S., Fishel, R., and Alnemri, E. S. 1999. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J. Biol. Chem. 274:17941-17945.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17941-17945
    • Saleh, A.1    Srinivasula, S.M.2    Acharya, S.3    Fishel, R.4    Alnemri, E.S.5
  • 32
    • 0033032444 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
    • Matsura, T., Kai, M., Fujii, Y., Ito, H., and Yamada, K. 1999. Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation. Free Radic. Res. 30:73-83.
    • (1999) Free Radic. Res. , vol.30 , pp. 73-83
    • Matsura, T.1    Kai, M.2    Fujii, Y.3    Ito, H.4    Yamada, K.5
  • 33
    • 0030792637 scopus 로고    scopus 로고
    • Multiple roles of glutathione in the central nervous system
    • Cooper, A. J. L. and Kristal, B. S. 1997. Multiple roles of glutathione in the central nervous system. Biol. Chem. 378:793-802.
    • (1997) Biol. Chem. , vol.378 , pp. 793-802
    • Cooper, A.J.L.1    Kristal, B.S.2
  • 34
    • 0033088957 scopus 로고    scopus 로고
    • The role of glutathione in the regulation of apoptosis
    • Hall, A. 1999. The role of glutathione in the regulation of apoptosis. Eur. J. Clin. Invest. 29:238-245.
    • (1999) Eur. J. Clin. Invest. , vol.29 , pp. 238-245
    • Hall, A.1
  • 35
    • 0001412747 scopus 로고    scopus 로고
    • Astrocytes provide cysteine to neurons by releasing glutathione
    • Wang, X. F. and Cynader, M. S. 2000. Astrocytes provide cysteine to neurons by releasing glutathione. J. Neurochem. 74:1434-1442.
    • (2000) J. Neurochem. , vol.74 , pp. 1434-1442
    • Wang, X.F.1    Cynader, M.S.2
  • 36
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin, L. F. H., Doherty, D. H., Lile, J. D., Bektesh, S., and Collins, F. 1993 GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.H.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 37
    • 0033769982 scopus 로고    scopus 로고
    • Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury
    • Abe, K. 2000. Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury. J. Cereb. Blood Flow Metab. 20:1393-1408.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 1393-1408
    • Abe, K.1
  • 38
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan, J. and Yanker, B. A. 2000. Apoptosis in the nervous system. Nature 407:802-809.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yanker, B.A.2
  • 40
    • 0032589586 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor prevents superoxide anion-induced death of PC12h cells stably expressing TrkB receptor via modulation of reactive oxygen species
    • Yamagata, T., Satoh, T., Ishikawa, Y., Nakatani, A., Yamada, M., Ikeuchi, T., and Hatanaka, H. 1999. Brain-derived neurotrophic factor prevents superoxide anion-induced death of PC12h cells stably expressing TrkB receptor via modulation of reactive oxygen species. Neurosci. Res. 35:9-17.
    • (1999) Neurosci. Res. , vol.35 , pp. 9-17
    • Yamagata, T.1    Satoh, T.2    Ishikawa, Y.3    Nakatani, A.4    Yamada, M.5    Ikeuchi, T.6    Hatanaka, H.7
  • 41
    • 0036708174 scopus 로고    scopus 로고
    • Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: Involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway
    • Toth, G., Yang, H., Anguelov, R. A., Vettraino, J., Wang, Y., and Acsadi, G. 2002. Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway. J. Neurosci. Res. 69:622-632.
    • (2002) J. Neurosci. Res. , vol.69 , pp. 622-632
    • Toth, G.1    Yang, H.2    Anguelov, R.A.3    Vettraino, J.4    Wang, Y.5    Acsadi, G.6
  • 42
    • 0034961705 scopus 로고    scopus 로고
    • Neuroimmunophilins: Novel neuroprotective and neuroregenerative targets
    • Guo, X., Dillman, J. F., Dawson, V. L., and Dawson, T. M. 2001. Neuroimmunophilins: novel neuroprotective and neuroregenerative targets. Ann. Neurol. 50:6-16.
    • (2001) Ann. Neurol. , vol.50 , pp. 6-16
    • Guo, X.1    Dillman, J.F.2    Dawson, V.L.3    Dawson, T.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.