5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation - An effect sensitive to NMDA receptor antagonism

Neuropharmacology

Volumn 47, Issue 2, 2004, Pages 195-204

  King, M V ^a   Sleight, A J ^b   Woolley, M L ^b   Topham, I A ^a   Marsden, C A ^a   Fone, K C F ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

5 HT6 receptor; Cognition; Glutamate; Object discrimination; Ro 04 6790; SB 271046

Indexed keywords

4 AMINO N [2,6 BIS(METHYLAMINO) 4 PYRIMIDINYL]BENZENESULFONAMIDE; 5 CHLORO N (4 METHOXY 3 PIPERAZIN 1 YLPHENYL) 3 METHYL 2 BENZOTHIOPHENE SULFONAMIDE; 5 CHLORO N [4 METHOXY 3 (1 PIPERAZINYL)PHENYL] 3 METHYL 2 BENZOTHIOPHENESULFONAMIDE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; SULFONAMIDE; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR BLOCKING AGENT; DIZOCILPINE MALEATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PYRIMIDINE DERIVATIVE; RO 4 6790; RO 4-6790; SEROTONIN RECEPTOR; THIOPHENE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; DISCRIMINATION LEARNING; DRUG EFFECT; EXPOSURE; MALE; MEMORY; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; ANIMAL; COGNITION; DRUG ANTAGONISM; EXPLORATORY BEHAVIOR; PERCEPTIVE DISCRIMINATION; SYNAPTIC TRANSMISSION;

ANIMALS; COGNITION; DISCRIMINATION (PSYCHOLOGY); DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; EXPLORATORY BEHAVIOR; MALE; PYRIMIDINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SULFONAMIDES; SYNAPTIC TRANSMISSION; THIOPHENES;

EID: 3042561627     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.03.012     Document Type: Article

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