NMDA antagonists produce site-selective impairment of accuracy in a delayed nonmatch-to-sample task in rats

Neuropharmacology

Volumn 41, Issue 8, 2001, Pages 916-927

  Willmore, Catherine B ^a,b   LaVecchia, Kari L ^a   Wiley, Jenny L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

Delayed nonmatch to sample; NMDA antagonists; Phencyclidine

Indexed keywords

2 AMINO 4,5 (1,2 CYCLOHEXYL) 7 PHOSPHONOHEPTANOIC ACID; 6,7 DICHLORO 5 NITRO 2,3 QUINOXALINEDIONE; DIZOCILPINE; ELIPRODIL; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENCYCLIDINE; SDZEAA 494; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG SELECTIVITY; MALE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE;

ANIMALS; ATAXIA; DISCRIMINATION LEARNING; EXCITATORY AMINO ACID ANTAGONISTS; MALE; PSYCHOMOTOR PERFORMANCE; RATS; RATS, LONG-EVANS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0035672936     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00143-5     Document Type: Article

References (39)

1. Processing of auditory stimuli during visual attention in patients with schizophrenia
2. The NMDA antagonist EAA 494 does not impair working memory in an operant DNMTP task in rats
3. Evaluation of the reinforcing effects of eliprodil in rhesus monkeys and its discriminative stimulus effects in rats
4. Behavioral pharmacology of two novel substituted quinoxalinedione glutamate antagonists
5. Disruption of learning by excitatory amino acid receptor antagonists
6. Pharmacological specificity of the discriminative stimulus properties of 2-amino-4, 5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid (NPC 12626), a competitive N-methyl-D-aspartate receptor antagonist
7. Prestimulus effects on human startle reflex in normals and schizophrenics
8. Effects of (+)-HA-966, CGS-197755, phencyclidine, and dizocilpine on repeated acquisition of response chains in pigeons: Systemic manipulation of central glycine sites
9. Effects of strychnine insensitive glycine receptor antagonists and sigma agents on working memory performance: Comparison with dizocilpine and scopolamine
10. Contrasting effects of the competitive NMDA antagonist CPP and the non-competitive NMDA antagonist MK 801 on performance of an operant delayed matching to position task in rats
11. NMDA receptors - Their role in long-term potentiation
12. Prepulse inhibition of the startle reflex in rats: Effects of compounds acting at various sites on the NMDA receptor complex
13. Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short term memory and on overt behaviour
14. Comparative effects of cholinergic drugs and lesions of nucleus basalis or fimbria-fornix on delayed matching in rats
15. Comparison of short-term memory deficits in animal models of ageing using an operant delayed response task in rats
16. Effects of delta-9 tetrahydrocannabinol on delayed match to sample performance in rats: Alterations in short-term memory associated with changes in task specific firing of hippocampal cells
17. Role of cortical N-methyl-D-aspartate receptors in auditory sensory memory and mismatch negativity generation: Implications for schizophrenia
18. Impaired mismatch negativity (MMN) generation in schizophrenia as a function of stimulus deviance, probability, and interstimulus/interdeviant interval
19. Schizophrenia-like deficits in auditory P1 and N1 refractoriness induced by the psychomimetic agent phencyclidine (PCP)
20. Low dose scopolamine affects discriminability but not rate of forgetting in delayed conditional discrimination
21. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
22. Effects of NMDA receptor ligands on sensorimotor gating in the rat
23. Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis
24. Evaluation of the reinforcing and discriminative stimulus effects of the N-methyl-D-aspartate competitive antagonist NPC 17742 in rhesus monkeys
25. Evaluation of the reinforcing and discriminative stimulus properties of the low-affinity N-methyl-D-aspartate channel blocker memantine
26. Lack of amnestic, psychotomimetic or impairing effect on psychomotor performance of eliprodil, a new NMDA antagonist
27. N-methyl-D-aspartate antagonists and working memory performance: Comparison with the effects of scopolamine, propranolol, diazepam, and phenylisopropyladenosine
28. Effects of the potassium channel blockers, apamin and 4-aminopyridine, on scopolamine-induced deficits in the delayed matching to position task in rats: A comparison with the cholinesterase inhibitor E2020
29. Specificity of memory measures in an adjusting delayed nonmatching-to-position task for rats
30. Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: Effects of scopolamine, 8-OH-DPAT and EAA antagonists
31. AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks
32. Effects of the NMDA antagonists CPP and MK-801 on delayed conditional discrimination
33. Attentive novelty detection in humans is governed by pre-attentive sensory memory
34. Characteristics of forgetting functions in delayed matching to sample
35. Effects of nitric oxide synthase inhibitors on timing and short-term memory in rats
36. Discriminative stimulus effects of site-selective N-methyl-D-aspartate antagonists in NPC 17742-trained rats and squirrel monkeys
37. The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats
38. Effects of site selective N-methyl-D-aspartate (NMDA) antagonists on delayed discrimination: Assessment of task accuracy and signal detection analysis to evaluate discriminability and bias